ONTOLOGY REPORT - ANNOTATIONS


Term:chemical synaptic transmission, postsynaptic
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Accession:GO:0099565 term browser browse the term
Definition:The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.
Synonyms:related_synonym: postsynaptic process involved in chemical synaptic transmission


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evoked excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Begain brain-enriched guanylate kinase-associated JBrowse link 6 132,936,964 132,972,569 RGD:1624291
excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317911
RGD:1624291
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625443
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:5129150
G Atxn1 ataxin 1 JBrowse link 17 19,160,986 19,533,814 RGD:1624291
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1600576
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:1624291
RGD:1600115
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit JBrowse link 3 60,445,657 60,460,724 RGD:1600115
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit JBrowse link 1 167,206,722 167,212,199 RGD:1600115
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit JBrowse link 15 42,808,897 42,825,179 RGD:1600115
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit JBrowse link 8 59,594,007 59,607,122 RGD:1624291
RGD:1600115
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:1600115
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit JBrowse link 8 59,561,817 59,590,172 RGD:1600115
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit JBrowse link 16 68,860,018 68,866,718 RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600115
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit JBrowse link 14 43,883,450 43,890,171 RGD:1600115
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit JBrowse link 10 56,390,671 56,403,255 RGD:1600115
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:1600115
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit JBrowse link 16 68,876,442 68,913,628 RGD:1600115
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit JBrowse link 8 59,610,489 59,629,073 RGD:1600115
G Chrnd cholinergic receptor nicotinic delta subunit JBrowse link 9 94,286,550 94,294,968 RGD:1600115
G Chrne cholinergic receptor nicotinic epsilon subunit JBrowse link 10 57,238,960 57,246,750 RGD:1600115
G Chrng cholinergic receptor nicotinic gamma subunit JBrowse link 9 94,302,218 94,308,591 RGD:1600115
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1624291
RGD:1600115
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:1600115
G Glra1 glycine receptor, alpha 1 JBrowse link 10 40,851,955 40,954,364 RGD:1600115
G Glra2 glycine receptor, alpha 2 JBrowse link X 30,612,894 30,832,078 RGD:1600115
G Glra3 glycine receptor, alpha 3 JBrowse link 16 37,676,959 37,908,221 RGD:1600115
G Glra4 glycine receptor, alpha 4 JBrowse link X 107,416,019 107,447,253 RGD:1600115
G Glrb glycine receptor, beta JBrowse link 2 179,768,040 179,842,612 RGD:1600115
G Grid2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 4 94,068,112 95,476,864 RGD:1624291
RGD:1600115
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1600115
RGD:1624291
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:1624291
RGD:1600115
G Grik5 glutamate ionotropic receptor kainate type subunit 5 JBrowse link 1 81,885,516 81,946,731 RGD:1624291
RGD:1600115
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:1600115
RGD:1624291
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:2325882
RGD:13792537
RGD:1624291
RGD:1600115
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1624291
RGD:13792537
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:1600115
RGD:13792537
RGD:1624291
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:1624291
RGD:13792537
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:1600968
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:1624291
RGD:1600115
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1624291
RGD:1600115
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1624291
G Mpp2 membrane palmitoylated protein 2 JBrowse link 10 89,998,284 90,030,766 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Npas4 neuronal PAS domain protein 4 JBrowse link 1 220,260,310 220,278,177 RGD:1624291
RGD:1600115
G Npff neuropeptide FF-amide peptide precursor JBrowse link 7 144,127,084 144,127,873 RGD:2316571
RGD:13792537
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:2316604
G P2rx1 purinergic receptor P2X 1 JBrowse link 10 59,566,268 59,581,328 RGD:1600115
G P2rx2 purinergic receptor P2X 2 JBrowse link 12 52,397,666 52,401,005 RGD:1600115
G P2rx3 purinergic receptor P2X 3 JBrowse link 3 72,403,992 72,447,801 RGD:1600115
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:1624291
RGD:1600115
G P2rx5 purinergic receptor P2X 5 JBrowse link 10 59,725,438 59,737,126 RGD:1600115
G P2rx6 purinergic receptor P2X 6 JBrowse link 11 87,434,929 87,445,221 RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1600115
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:10043779
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1624291
RGD:1600115
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 JBrowse link 13 44,578,208 44,649,876 RGD:1624291
RGD:1600115
G Sez6 seizure related 6 homolog JBrowse link 10 64,865,802 64,915,461 RGD:1624291
RGD:1600115
G Slc17a7 solute carrier family 17 member 7 JBrowse link 1 101,161,265 101,172,292 RGD:1624291
RGD:1600115
G Slc29a1 solute carrier family 29 member 1 JBrowse link 9 17,784,468 17,799,008 RGD:1299118
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
RGD:1600115
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:1600115
inhibitory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1624291
RGD:1600115
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129137
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1624291
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:1624291
RGD:1600115
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:4891944
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:1600115
RGD:1624291
G Gabrb3 gamma-aminobutyric acid type A receptor beta 3 subunit JBrowse link 1 113,034,251 113,265,364 RGD:1624291
RGD:1600115
G Glra1 glycine receptor, alpha 1 JBrowse link 10 40,851,955 40,954,364 RGD:1600115
RGD:1624291
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1624291
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:1624291
RGD:1600115
G Insyn1 inhibitory synaptic factor 1 JBrowse link 8 63,286,841 63,297,080 RGD:1600115
RGD:1624291
G Insyn2a inhibitory synaptic factor 2A JBrowse link 1 207,116,698 207,171,885 RGD:1624291
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:1624291
RGD:8553502
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:8554851
RGD:1624291
RGD:1600115
G Npas4 neuronal PAS domain protein 4 JBrowse link 1 220,260,310 220,278,177 RGD:1600115
RGD:1624291
modulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1624291
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 JBrowse link 9 11,031,847 11,055,285 RGD:13463484
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:11535099
G Tmem108 transmembrane protein 108 JBrowse link 8 111,968,568 112,265,623 RGD:1624291
G Zmynd8 zinc finger, MYND-type containing 8 JBrowse link 3 162,480,766 162,594,145 RGD:8554267
modulation of inhibitory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398809
negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbln1 cerebellin 1 precursor JBrowse link 19 20,607,507 20,611,316 RGD:1624291
RGD:1600115
G Celf4 CUGBP, Elav-like family member 4 JBrowse link 18 17,689,090 18,079,835 RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:10044262
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:1642608
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413844
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G S1pr2 sphingosine-1-phosphate receptor 2 JBrowse link 8 21,984,914 21,995,806 RGD:1624291
RGD:1600115
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209020
positive regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baiap2 BAI1-associated protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:9684984
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:13514092
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600115
RGD:1624291
G Cux2 cut-like homeobox 2 JBrowse link 12 40,016,774 40,221,067 RGD:1624291
RGD:1600115
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398809
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554754
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:7248611
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:10449514
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:8554754
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:8554754
G Grip2 glutamate receptor interacting protein 2 JBrowse link 4 123,585,184 123,636,040 RGD:4107359
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13506836
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:4107027
G Neto1 neuropilin and tolloid like 1 JBrowse link 18 83,471,342 83,585,043 RGD:1624291
RGD:1600115
G Neto2 neuropilin and tolloid like 2 JBrowse link 19 22,450,579 22,486,530 RGD:1624291
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:10414080
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8553502
RGD:1624291
RGD:8554379
RGD:8554760
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:8554098
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8553497
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1600115
RGD:1624291
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:13524537
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
RGD:1600115
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:1600115
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:1624291
RGD:13792537
RGD:1600115
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:13792537
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1600115
RGD:13792537
RGD:1624291
RGD:7349315
G Ssh1 slingshot protein phosphatase 1 JBrowse link 12 48,403,184 48,447,964 RGD:11535133
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:1624291
RGD:1600115
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1624291
RGD:1600115
G Tbc1d24 TBC1 domain family, member 24 JBrowse link 10 13,551,100 13,576,739 RGD:11537391
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
positive regulation of inhibitory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:10047060
G Igsf9b immunoglobulin superfamily, member 9B JBrowse link 8 28,352,497 28,398,659 RGD:1624291
RGD:1600115
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:8554527
RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:8554851
G Ntsr1 neurotensin receptor 1 JBrowse link 3 175,982,313 176,046,345 RGD:9831120
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
RGD:1600115
RGD:10047275
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:1600115
G Unc13b unc-13 homolog B JBrowse link 5 58,505,449 58,714,396 RGD:10047275
positive regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1600115
RGD:1624291
G Afdn afadin, adherens junction formation factor JBrowse link 1 53,713,873 53,861,918 RGD:13838731
G Igsf11 immunoglobulin superfamily, member 11 JBrowse link 11 64,286,691 64,421,248 RGD:11085699
regulation of acetylcholine-gated cation channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:704387
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:1624291
G Dmpk DM1 protein kinase JBrowse link 1 79,988,096 79,999,358 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    signaling 7023
      cell-cell signaling 1616
        cell surface receptor signaling pathway involved in cell-cell signaling 541
          chemical synaptic transmission, postsynaptic 121
            excitatory postsynaptic potential + 112
            inhibitory postsynaptic potential + 23
Path 2
Term Annotations click to browse term
  biological_process 17941
    cellular process 16091
      cell communication 7118
        cell-cell signaling 1616
          synaptic signaling 880
            trans-synaptic signaling 860
              anterograde trans-synaptic signaling 851
                chemical synaptic transmission 851
                  chemical synaptic transmission, postsynaptic 121
                    excitatory postsynaptic potential + 112
                    inhibitory postsynaptic potential + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.