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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin receptor activity
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Accession:GO:0099589 term browser browse the term
Definition:Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.


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G protein-coupled serotonin receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Drd1 dopamine receptor D1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd4 dopamine receptor D4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Hrh1 histamine receptor H 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hrh2 histamine receptor H 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hrh3 histamine receptor H3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hrh4 histamine receptor H4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IMP
IBA
IEA
ISO
IDA
PMID:21873635
GO_REF:0000002
(MGI:MGI:1314969|PMID:9826725), (MGI:MGI:64131|PMID:8254366)
(PMID:22957663), (PMID:8393041)
InterPro
RGD
PMID:8254366, PMID:8393041, PMID:9826725, PMID:22957663, PMID:12149253, PMID:21873635, PMID:8271204 GO_REF:0000002, MGI:MGI:1314969, MGI:MGI:64131, RGD:730812, RGD:13792537, RGD:2303617 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IDA
IBA
ISO
PMID:21873635
(MGI:MGI:4821070|PMID:17325130)
(PMID:1315531)
RGD PMID:1315531, PMID:17325130, PMID:15328035, PMID:21873635 MGI:MGI:4821070, MGI:MGI:64075, RGD:1358659, RGD:13792537 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D ISO
IBA
ISS
(MGI:MGI:48584|PMID:1557407)
PMID:21873635
GO_REF:0000024
(PMID:1652050)
RGD
UniProt
PMID:1557407, PMID:1652050, PMID:21873635 GO_REF:0000024, MGI:MGI:48584, RGD:13792537 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:21422162), (PMID:8380639)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:8380639, PMID:21422162, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IDA
IBA
ISO
PMID:21873635
(PMID:15862800)
(PMID:15862800), (PMID:7582481)
RGD PMID:7582481, PMID:15862800, PMID:19016481, PMID:21873635 RGD:5133450, RGD:13792537 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO
IBA
ISS
(MGI:MGI:4821070|PMID:17325130)
(PMID:12970106), (PMID:15625277), (PMID:15862800), (PMID:7582481), (PMID:7926008)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:7582481, PMID:7926008, PMID:12970106, PMID:15625277, PMID:15862800, PMID:17325130, PMID:21873635 GO_REF:0000024, MGI:MGI:4821070, RGD:13792537 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP
ISO
IBA
IEA
IDA
(PMID:12970106), (PMID:7582481)
PMID:21873635
(MGI:MGI:5140621|PMID:21835345)
GO_REF:0000002
PMID:8626447
RGD
InterPro
PMID:7582481, PMID:12970106, PMID:21835345, PMID:15663485, PMID:21873635, PMID:8626447 GO_REF:0000002, MGI:MGI:5140621, RGD:1358734, RGD:13792537, RGD:8554296 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 IMP
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
GO_REF:0000002
(PMID:16102731)
Ensembl
InterPro
RGD
PMID:16102731, PMID:10220570, PMID:21873635, PMID:7796807 GO_REF:0000002, GO_REF:0000107, RGD:729213, RGD:13792537, RGD:729350 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A IMP
IBA
ISO
PMID:21873635
(PMID:7988681)
RGD PMID:7988681, PMID:7682702, PMID:21873635 RGD:62385, RGD:13792537 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:37,479,758...37,492,680
Ensembl chr13:37,479,758...37,492,680
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7680751, PMID:21873635 RGD:729174, RGD:13792537 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA
IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:8394362, PMID:21873635 GO_REF:0000002, RGD:625369, RGD:13792537 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G LOC100909683 olfactory receptor 63-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,722,054...15,723,428
Ensembl chr 7:15,722,177...15,723,127
JBrowse link
G LOC103693822 olfactory receptor 11H4-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,589,957...27,590,931
Ensembl chr15:27,499,024...27,499,998
Ensembl chr15:27,499,024...27,499,998
JBrowse link
G LOC103694905 5-hydroxytryptamine receptor 7 IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537
G Olr1090 olfactory receptor 1090 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,523,926...15,524,635
Ensembl chr 7:15,523,926...15,706,893
JBrowse link
G Olr1091 olfactory receptor 1091 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,628,665...15,629,600
Ensembl chr 7:15,628,665...15,629,600
JBrowse link
G Olr1095 olfactory receptor 1095 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,621,989...15,622,945
Ensembl chr 7:15,621,989...15,622,945
JBrowse link
G Olr1576 olfactory receptor 1576 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:91,481,461...91,482,390
Ensembl chr13:91,481,461...91,482,390
JBrowse link
G Olr1622 olfactory receptor 1622 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,438,853...27,439,791
Ensembl chr15:27,438,853...27,439,791
JBrowse link
G Olr1631 olfactory receptor 1631 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,484,665...27,485,639
Ensembl chr15:27,484,665...27,485,639
JBrowse link
G Olr1632 olfactory receptor 1632 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,499,024...27,499,998
Ensembl chr15:27,499,024...27,499,998
JBrowse link
G Olr1635 olfactory receptor 1635 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,548,762...27,549,748
Ensembl chr15:27,548,762...27,549,748
JBrowse link
G Olr1875 olfactory receptor 1875 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,877,048...172,878,013
Ensembl chr 1:172,877,087...172,878,013
JBrowse link
G Olr240 olfactory receptor 240 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,094,587...172,100,921
Ensembl chr 1:172,099,992...172,100,921
JBrowse link
G Olr241 olfactory receptor 241 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,129,514...172,130,446
Ensembl chr 1:172,129,514...172,130,446
JBrowse link
G Olr245 olfactory receptor 245 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,242,504...172,243,487
Ensembl chr 1:172,242,504...172,243,487
JBrowse link
G Olr515 olfactory receptor 515 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:73,988,945...73,989,910
Ensembl chr 3:73,988,945...73,989,910
JBrowse link
G Olr517 olfactory receptor 517 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:74,052,884...74,059,247
Ensembl chr 3:74,058,255...74,059,247
JBrowse link
G Olr518 olfactory receptor 518 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:74,370,435...74,379,077
Ensembl chr 3:74,370,435...74,371,385
JBrowse link
G Olr519 olfactory receptor 519 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:74,341,751...74,342,719
Ensembl chr 3:74,341,751...74,342,719
JBrowse link
Gq/11-coupled serotonin receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A ISO
IEA
(PMID:18703043)
GO_REF:0000107
RGD
Ensembl
PMID:18703043 GO_REF:0000107 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO
IEA
(PMID:18703043)
GO_REF:0000107
RGD
Ensembl
PMID:18703043 GO_REF:0000107 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO
ISS
(PMID:18703043)
GO_REF:0000024
RGD
UniProt
PMID:18703043 GO_REF:0000024 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    molecular transducer activity 2656
      signaling receptor activity 2656
        transmembrane signaling receptor activity 2499
          serotonin receptor activity 42
            G protein-coupled serotonin receptor activity + 42
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.