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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of calcineurin-mediated signaling
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Accession:GO:0106057 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling.


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negative regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:MGI:5554485|PMID:24234654) RGD PMID:24234654 MGI:MGI:5554485 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 IMP
ISO
PMID:19287093
(MGI:MGI:6368228|PMID:25147342)
(PMID:15955804), (PMID:19287093), (PMID:25147342)
RGD PMID:15955804, PMID:19287093, PMID:25147342, PMID:19287093 MGI:MGI:6368228, RGD:10047333 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 ISO
ISS
(PMID:10593895)
GO_REF:0000024
RGD
UniProt
PMID:10593895 GO_REF:0000024 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989
JBrowse link
G Cmya5 cardiomyopathy associated 5 ISO MGI:MGI:107164 (MGI:MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:MGI:5056263 NCBI chr 2:22,646,694...22,744,536
Ensembl chr 2:22,646,712...22,744,407
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 ISO (PMID:16511445) RGD PMID:16511445 NCBI chr 7:61,785,423...61,816,775
Ensembl chr 7:61,786,309...61,798,729
JBrowse link
G Fhl2 four and a half LIM domains 2 IMP
IBA
ISO
PMID:22851699
PMID:21873635
(MGI:MGI:5444535|PMID:22851699)
(PMID:22851699)
RGD PMID:22851699, PMID:22851699, PMID:21873635 MGI:MGI:5444535, RGD:13601990, RGD:13792537 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISS
ISO
IEA
GO_REF:0000024
(PMID:9072970)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9072970 GO_REF:0000024, GO_REF:0000107 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Homer2 homer scaffold protein 2 ISS
ISO
GO_REF:0000024
(PMID:18218901)
UniProt
RGD
PMID:18218901 GO_REF:0000024 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Homer3 homer scaffold protein 3 ISS
ISO
GO_REF:0000024
(PMID:18218901)
UniProt
RGD
PMID:18218901 GO_REF:0000024 NCBI chr16:20,880,447...20,890,968
Ensembl chr16:20,881,518...20,890,949
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (MGI:MGI:3795069|PMID:18347059) RGD PMID:18347059 MGI:MGI:3795069 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO (MGI:MGI:3795069|PMID:18347059) RGD PMID:18347059 MGI:MGI:3795069 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myoz1 myozenin 1 ISO (MGI:MGI:3831256|PMID:18846255) RGD PMID:18846255 MGI:MGI:3831256 NCBI chr15:4,077,066...4,084,306
Ensembl chr15:4,077,091...4,084,314
JBrowse link
G Myoz2 myozenin 2 ISO (MGI:MGI:3513659|PMID:15543153) RGD PMID:15543153 MGI:MGI:3513659 NCBI chr 2:227,180,887...227,207,629
Ensembl chr 2:227,180,886...227,207,635
JBrowse link
G Prnp prion protein ISO (MGI:MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:MGI:4943618 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Rcan1 regulator of calcineurin 1 ISS
ISO
GO_REF:0000024
(PMID:12809556)
UniProt
RGD
PMID:12809556 GO_REF:0000024 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Tbc1d10c TBC1 domain family, member 10C ISO MGI:MGI:5578034 (MGI:MGI:5576870|PMID:23109291) RGD PMID:23109291 MGI:MGI:5576870 NCBI chr 1:219,431,094...219,439,102
Ensembl chr 1:219,431,997...219,438,779
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      negative regulation of response to stimulus 1635
        negative regulation of signal transduction 1235
          negative regulation of intracellular signal transduction 542
            negative regulation of calcium-mediated signaling 21
              negative regulation of calcineurin-mediated signaling 16
                negative regulation of calcineurin-NFAT signaling cascade 16
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological process 13075
        regulation of cellular process 12561
          signal transduction 7011
            intracellular signal transduction 2594
              second-messenger-mediated signaling 467
                calcium-mediated signaling 217
                  regulation of calcium-mediated signaling 84
                    negative regulation of calcium-mediated signaling 21
                      negative regulation of calcineurin-mediated signaling 16
                        negative regulation of calcineurin-NFAT signaling cascade 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.