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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of biomineralization
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Accession:GO:0110150 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
Synonyms:exact_synonym: negative regulation of biomineralisation;   negative regulation of mineralisation;   negative regulation of mineralization
 narrow_synonym: negative regulation of biomineral formation


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negative regulation of biomineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ucma upper zone of growth plate and cartilage matrix associated ISO MGI:MGI:5314628 (MGI:MGI:6163471|PMID:29563538) RGD PMID:29563538 MGI:MGI:6163471 NCBI chr17:77,252,099...77,262,301
Ensembl chr17:77,252,100...77,261,731
JBrowse link
negative regulation of biomineral tissue development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gas6 growth arrest specific 6 ISO
ISS
(PMID:20048160)
GO_REF:0000024
RGD
UniProt
PMID:20048160 GO_REF:0000024 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO (MGI:MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:MGI:6158746 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO (MGI:MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:MGI:6158746 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Nos3 nitric oxide synthase 3 IEA
ISO
GO_REF:0000107
(MGI:MGI:6158885|PMID:23583836)
Ensembl
RGD
PMID:23583836 GO_REF:0000107, MGI:MGI:6158885 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:6158728|PMID:26491108), (MGI:MGI:6158885|PMID:23583836) RGD PMID:23583836, PMID:26491108 MGI:MGI:6158728, MGI:MGI:6158885 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO
ISS
(MGI:MGI:4947506|PMID:20056916)
(PMID:22110751)
GO_REF:0000024
RGD
UniProt
PMID:20056916, PMID:22110751 GO_REF:0000024, MGI:MGI:4947506 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (PMID:26634652)
(MGI:MGI:5921830|PMID:26634652)
RGD PMID:26634652 MGI:MGI:5921830 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein IMP
ISS
ISO
GO_REF:0000024
(MGI:MGI:3687916|PMID:12556469)
UniProt
RGD
PMID:12556469, PMID:8702833 GO_REF:0000024, MGI:MGI:3687916, RGD:1626074 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Bcor BCL6 co-repressor ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO (PMID:21403648) RGD PMID:21403648 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ecm1 extracellular matrix protein 1 ISO
ISS
(PMID:11165938)
GO_REF:0000024
RGD
UniProt
PMID:11165938 GO_REF:0000024 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:5607146|PMID:25479107), (MGI:MGI:6220772|PMID:30111653), (MGI:MGI:6294341|PMID:22510396)
UniProt
RGD
PMID:22510396, PMID:25479107, PMID:30111653 GO_REF:0000024, MGI:MGI:5607146, MGI:MGI:6220772, MGI:MGI:6294341 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Fgf23 fibroblast growth factor 23 ISO (PMID:18282132) RGD PMID:18282132 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Gata1 GATA binding protein 1 ISO MGI:MGI:2177586 (MGI:MGI:3653541|PMID:15005853) RGD PMID:15005853 MGI:MGI:3653541 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEA
MGI:MGI:1857719 (MGI:MGI:3777866|PMID:17181398)
GO_REF:0000107
RGD
Ensembl
PMID:17181398 GO_REF:0000107, MGI:MGI:3777866 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO MGI:MGI:2180017 (MGI:MGI:2178869|PMID:11790802) RGD PMID:11790802 MGI:MGI:2178869 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO MGI:MGI:2448895 (MGI:MGI:2448336|PMID:12421822), (MGI:MGI:3851320|PMID:15843468), (MGI:MGI:5431257|PMID:22766095) RGD PMID:12421822, PMID:15843468, PMID:22766095 MGI:MGI:2448336, MGI:MGI:3851320, MGI:MGI:5431257 NCBI chr14:6,782,011...6,793,561
Ensembl chr14:6,782,012...6,793,558
JBrowse link
G Nfe2 nuclear factor, erythroid 2 ISO MGI:MGI:1857224 (MGI:MGI:3653541|PMID:15005853) RGD PMID:15005853 MGI:MGI:3653541 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO
ISS
(MGI:MGI:3713957|PMID:17537919)
GO_REF:0000024
RGD
UniProt
PMID:17537919 GO_REF:0000024, MGI:MGI:3713957 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO MGI:MGI:2158693 (MGI:MGI:2135696|PMID:11371614) RGD PMID:11371614 MGI:MGI:2135696 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Srgn serglycin ISO
IBA
ISS
(PMID:16870619)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:16870619, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23081848 RGD:10003033 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Pth parathyroid hormone IMP PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rflna refilin A ISO
IBA
MGI:MGI:1923816 (MGI:MGI:5570967|PMID:24436304)
PMID:21873635
RGD PMID:24436304, PMID:21873635 MGI:MGI:5570967, RGD:13792537 NCBI chr12:37,038,732...37,047,628
Ensembl chr12:37,038,733...37,047,628
JBrowse link
G Rflnb refilin B ISO
IBA
MGI:MGI:1920371 (MGI:MGI:5570967|PMID:24436304)
PMID:21873635
RGD PMID:24436304, PMID:21873635 MGI:MGI:5570967, RGD:13792537 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380
JBrowse link
negative regulation of tooth mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspn asporin ISO (MGI:MGI:3722035|PMID:17522060) RGD PMID:17522060 MGI:MGI:3722035 NCBI chr17:14,655,958...14,681,355
Ensembl chr17:14,656,009...14,679,409
JBrowse link
G Bcor BCL6 co-repressor ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    negative regulation of biological process 5696
      negative regulation of biomineralization 30
        negative regulation of biomineral tissue development + 29
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of biomineralization 102
          negative regulation of biomineralization 30
            negative regulation of biomineral tissue development + 29
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.