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ONTOLOGY REPORT - ANNOTATIONS


Term:olefinic compound biosynthetic process
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Accession:GO:0120255 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms:exact_synonym: alkene substituted compound anabolic process;   alkene substituted compound anabolism;   alkene substituted compound biosynthesis;   alkene substituted compound biosynthetic process;   alkene substituted compound synthesis


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H IMP
IEA
ISO
PMID:19342457
GO_REF:0000107
(PMID:19342457)
Ensembl
RGD
PMID:19342457, PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IMP
IBA
PMID:19342457
PMID:21873635
UniProt
GO_Central
PMID:19342457, PMID:21873635 RGD:4891166, RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IDA
IBA
ISO
PMID:21873635
(PMID:19342457), (PMID:2256920)
RGD PMID:2256920, PMID:19342457, PMID:11832364, PMID:21873635 RGD:727991, RGD:13792537 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 ISO (PMID:1741400), (PMID:19342457), (PMID:2256920), (PMID:23322723) RGD PMID:1741400, PMID:2256920, PMID:19342457, PMID:23322723 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H IMP
IEA
ISO
PMID:19342457
GO_REF:0000107
(PMID:19342457)
Ensembl
RGD
PMID:19342457, PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IMP PMID:19342457 UniProt PMID:19342457 RGD:4891166
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 ISO (PMID:19342457), (PMID:2022736), (PMID:8506298) RGD PMID:2022736, PMID:8506298, PMID:19342457 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 NOT ISO (PMID:9703385)
(PMID:19342457)
RGD PMID:9703385, PMID:19342457 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
hepoxilin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IDA
IBA
PMID:23382512
PMID:21873635
UniProt
GO_Central
PMID:23382512, PMID:21873635 RGD:8554649, RGD:13792537 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type IDA
IBA
PMID:23382512
PMID:21873635
UniProt
GO_Central
PMID:23382512, PMID:21873635 RGD:8554649, RGD:13792537 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Alox12e arachidonate 12-lipoxygenase, epidermal IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:56,927,676...56,935,141
Ensembl chr10:56,927,676...56,935,141
JBrowse link
G Alox15 arachidonate 15-lipoxygenase IDA
IBA
PMID:21873635
PMID:23382512
RGD
GO_Central
UniProt
PMID:15123652, PMID:21873635, PMID:23382512 RGD:5509794, RGD:13792537, RGD:8554649 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B IDA
IBA
PMID:23382512
PMID:21873635
UniProt
GO_Central
PMID:23382512, PMID:21873635 RGD:8554649, RGD:13792537 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 IDA
IBA
ISO
PMID:23382512
PMID:21873635
(MGI:MGI:3694035|PMID:17045234), (MGI:MGI:5488571|PMID:22832496)
(PMID:12881489), (PMID:17045234)
RGD PMID:12881489, PMID:17045234, PMID:22832496, PMID:23382512, PMID:21873635 MGI:MGI:3694035, MGI:MGI:5488571, RGD:8554649, RGD:13792537 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISS
ISO
GO_REF:0000024
(PMID:21046276)
UniProt
RGD
PMID:21046276 GO_REF:0000024 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21046276)
UniProt
Ensembl
RGD
PMID:21046276 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISS
ISO
GO_REF:0000024
(PMID:21046276)
UniProt
RGD
PMID:21046276 GO_REF:0000024 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 ISO
IEA
(PMID:19584291)
GO_REF:0000107
RGD
Ensembl
PMID:19584291 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp5 bone morphogenetic protein 5 ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Rest RE1-silencing transcription factor IMP
ISO
PMID:19342457
(PMID:19342457)
RGD PMID:19342457, PMID:19342457 RGD:4891166 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 ISO
IEA
(PMID:19584291)
GO_REF:0000107
RGD
Ensembl
PMID:19584291 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp5 bone morphogenetic protein 5 ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Rest RE1-silencing transcription factor IMP
ISO
PMID:19342457
(PMID:19342457)
RGD PMID:19342457, PMID:19342457 RGD:4891166 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 ISO (MGI:MGI:3839065|PMID:18818293) RGD PMID:18818293 MGI:MGI:3839065 NCBI chr 1:101,205,426...101,210,675
Ensembl chr 1:101,205,426...101,210,675
JBrowse link
G Wnt4 Wnt family member 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:2675528|PMID:12949260)
(PMID:12949260)
Ensembl
RGD
PMID:12949260 GO_REF:0000107, MGI:MGI:2675528 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 ISO (PMID:16527843) RGD PMID:16527843 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Wnt4 Wnt family member 4 IEA
ISO
GO_REF:0000107
(PMID:16981135)
Ensembl
RGD
PMID:16981135 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 IEA
ISO
GO_REF:0000107
(PMID:16981135)
Ensembl
RGD
PMID:16981135 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116
G Scp2 sterol carrier protein 2 ISO (PMID:1703300) RGD PMID:1703300 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 ISO MGI:MGI:3042568 (MGI:MGI:3039987|PMID:14963026) RGD PMID:14963026 MGI:MGI:3039987 NCBI chr10:86,313,430...86,335,868
Ensembl chr10:86,313,383...86,335,923
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 ISS
ISO
GO_REF:0000024
(PMID:29403011)
UniProt
RGD
PMID:29403011 GO_REF:0000024 NCBI chr11:82,862,664...82,876,165
Ensembl chr11:83,883,879...83,897,394
JBrowse link
G LOC108348101 chloride channel protein 2 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:83,883,428...83,897,396
Ensembl chr11:83,883,879...83,897,394
JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) ISO (PMID:18628520), (PMID:23132696)
(MGI:MGI:3623644|PMID:16356929)
RGD PMID:16356929, PMID:18628520, PMID:23132696 MGI:MGI:3623644 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G Egr1 early growth response 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:82584|PMID:8703054)
Ensembl
UniProt
RGD
PMID:8703054 GO_REF:0000024, GO_REF:0000107, MGI:MGI:82584 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:79,097,208...79,097,285
Ensembl chr 5:79,097,208...79,097,285
JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 ISO (PMID:19336506) RGD PMID:19336506 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A ISO (MGI:MGI:4352991|PMID:19398553) RGD PMID:19398553 MGI:MGI:4352991 NCBI chr19:880,024...887,144
Ensembl chr19:880,024...887,144
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:22429315 RGD:7775068 NCBI chr 1:248,982,039...250,300,952 JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 ISO (PMID:16983398) RGD PMID:16983398 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:19883722 RGD:4145609 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO
IEA
MGI:MGI:2154536 (MGI:MGI:1261712|PMID:9618522)
GO_REF:0000107
RGD
Ensembl
PMID:9618522 GO_REF:0000107, MGI:MGI:1261712 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 IDA
ISO
(MGI:MGI:1267145|PMID:9658408) RGD PMID:9658408, PMID:8612487 MGI:MGI:1267145, RGD:728619 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEA GO_REF:0000041
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002, GO_REF:0000041 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:16467141 RGD:4889544
G Srd5a2 steroid 5 alpha-reductase 2 ISO
ISS
(PMID:10898110)
GO_REF:0000024
RGD
UniProt
PMID:10898110 GO_REF:0000024 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:19883722 RGD:4145609 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      biosynthetic process 6222
        olefinic compound biosynthetic process 43
          (-)-secologanin biosynthetic process 0
          abscisic acid biosynthetic process + 0
          aldosterone biosynthetic process + 13
          all-trans-neoxanthin biosynthetic process 0
          androst-4-ene-3,17-dione biosynthetic process + 0
          chalcone biosynthetic process 0
          chanoclavine-I aldehyde biosynthetic process + 0
          cinnamic acid biosynthetic process + 0
          cinnamic acid ester biosynthetic process + 0
          cortisol biosynthetic process + 11
          ferulate biosynthetic process 0
          funalenone biosynthetic process 0
          geraniol biosynthetic process 0
          helvolic acid biosynthetic process + 0
          hepoxilin biosynthetic process 11
          isopentenol biosynthetic process 0
          kojic acid biosynthetic process + 0
          olefin biosynthetic process + 0
          prenol biosynthetic process 0
          progesterone biosynthetic process + 8
          sinapate biosynthetic process 0
          terrequinone A biosynthetic process + 0
          testosterone biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        olefinic compound metabolic process 135
          olefinic compound biosynthetic process 43
            (-)-secologanin biosynthetic process 0
            abscisic acid biosynthetic process + 0
            aldosterone biosynthetic process + 13
            all-trans-neoxanthin biosynthetic process 0
            androst-4-ene-3,17-dione biosynthetic process + 0
            chalcone biosynthetic process 0
            chanoclavine-I aldehyde biosynthetic process + 0
            cinnamic acid biosynthetic process + 0
            cinnamic acid ester biosynthetic process + 0
            cortisol biosynthetic process + 11
            ferulate biosynthetic process 0
            funalenone biosynthetic process 0
            geraniol biosynthetic process 0
            helvolic acid biosynthetic process + 0
            hepoxilin biosynthetic process 11
            isopentenol biosynthetic process 0
            kojic acid biosynthetic process + 0
            olefin biosynthetic process + 0
            prenol biosynthetic process 0
            progesterone biosynthetic process + 8
            sinapate biosynthetic process 0
            terrequinone A biosynthetic process + 0
            testosterone biosynthetic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.