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ONTOLOGY REPORT - ANNOTATIONS


Term:amyloid-beta clearance by cellular catabolic process
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Accession:GO:0150094 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms:narrow_synonym: amyloid-beta clearance by phagocytosis


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amyloid-beta clearance by cellular catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 ISS
ISO
GO_REF:0000024
(MGI:MGI:6271506|PMID:27472885)
UniProt
RGD
PMID:27472885 GO_REF:0000024, MGI:MGI:6271506 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Cd36 CD36 molecule IMP
ISO
PMID:18941241
(PMID:18941241)
RGD PMID:18941241, PMID:18941241 RGD:13825436 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Ide insulin degrading enzyme IMP
ISO
PMID:18941241
(PMID:23525105)
RGD PMID:23525105, PMID:18941241 RGD:13825436 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Ldlr low density lipoprotein receptor IEA
ISO
GO_REF:0000107
(MGI:MGI:5902678|PMID:22383525)
Ensembl
RGD
PMID:22383525 GO_REF:0000107, MGI:MGI:5902678 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lrp1 LDL receptor related protein 1 ISO (PMID:23152628), (PMID:24305823)
UniProtKB:P05067|UniProtKB:P49768 (MGI:MGI:5465209|PMID:23152628), (MGI:MGI:5529723|PMID:24305823), (MGI:MGI:5897551|PMID:21289173)
RGD PMID:21289173, PMID:23152628, PMID:24305823 MGI:MGI:5465209, MGI:MGI:5529723, MGI:MGI:5897551 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Lrp4 LDL receptor related protein 4 ISO (PMID:18289866) RGD PMID:18289866 NCBI chr 3:80,362,643...80,416,684
Ensembl chr 3:80,362,858...80,416,679
JBrowse link
G Mme membrane metallo-endopeptidase IMP
ISO
PMID:18941241
UniProtKB:P05067 (PMID:15100223), (PMID:24825898)
RGD PMID:15100223, PMID:24825898, PMID:18941241 RGD:13825436 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    multicellular organismal process 9055
      amyloid-beta clearance 36
        amyloid-beta clearance by cellular catabolic process 7
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      catabolic process 2543
        cellular catabolic process 2170
          amyloid-beta clearance by cellular catabolic process 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.