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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pigbos1 PIGB opposite strand 1 JBrowse link 8 79,715,337 79,719,706 RGD:1624291
RGD:1600115
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf6b activating transcription factor 6 beta JBrowse link 20 4,414,283 4,422,283 RGD:1624291
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
RGD:10047363
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crebrf CREB3 regulatory factor JBrowse link 10 16,693,846 16,753,162 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:1624291
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:1624291
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1600115
G Pdia6 protein disulfide isomerase family A, member 6 JBrowse link 6 42,568,269 42,585,654 RGD:1624291
G Ufl1 Ufm1-specific ligase 1 JBrowse link 5 39,616,479 39,650,894 RGD:1624291
RGD:1600115
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:1624291
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1600115
RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:13792537
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cops5 COP9 signalosome subunit 5 JBrowse link 5 8,876,090 8,894,345 RGD:1624291
G Ficd FIC domain protein adenylyltransferase JBrowse link 12 48,658,283 48,663,175 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    regulation of biological process 12920
      regulation of response to stimulus 4053
        regulation of signal transduction 2971
          regulation of endoplasmic reticulum unfolded protein response 25
            negative regulation of endoplasmic reticulum unfolded protein response + 13
            positive regulation of endoplasmic reticulum unfolded protein response + 10
            regulation of ATF6-mediated unfolded protein response + 3
            regulation of IRE1-mediated unfolded protein response + 10
            regulation of PERK-mediated unfolded protein response + 7
Path 2
Term Annotations click to browse term
  biological_process 19678
    response to stimulus 10494
      cellular response to stimulus 8832
        cellular response to chemical stimulus 3491
          cellular response to organic substance 2822
            cellular response to topologically incorrect protein 122
              cellular response to unfolded protein 99
                endoplasmic reticulum unfolded protein response 72
                  regulation of endoplasmic reticulum unfolded protein response 25
                    negative regulation of endoplasmic reticulum unfolded protein response + 13
                    positive regulation of endoplasmic reticulum unfolded protein response + 10
                    regulation of ATF6-mediated unfolded protein response + 3
                    regulation of IRE1-mediated unfolded protein response + 10
                    regulation of PERK-mediated unfolded protein response + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.