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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900103 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: activation of ER unfolded protein response;   activation of erUPR;   positive regulation of ER unfolded protein response;   positive regulation of erUPR;   up regulation of erUPR;   up-regulation of ER unfolded protein response;   up-regulation of endoplasmic reticulum unfolded protein response;   upregulation of ER unfolded protein response;   upregulation of endoplasmic reticulum unfolded protein response;   upregulation of erUPR
 narrow_synonym: activation of endoplasmic reticulum unfolded protein response
 related_synonym: activation of SREBP-mediated signalling pathway;   positive regulation of SREBP-mediated signalling pathway;   up regulation of SREBP-mediated signalling pathway;   upregulation of SREBP-mediated signalling pathway


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positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1600115
RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:13792537
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:1624291
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      signal transduction 6968
        positive regulation of signal transduction 1673
          positive regulation of endoplasmic reticulum unfolded protein response 10
            positive regulation of ATF6-mediated unfolded protein response 1
            positive regulation of IRE1-mediated unfolded protein response 2
            positive regulation of PERK-mediated unfolded protein response 4
Path 2
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      cellular response to stimulus 8858
        cellular response to chemical stimulus 3497
          cellular response to organic substance 2825
            cellular response to topologically incorrect protein 122
              cellular response to unfolded protein 99
                endoplasmic reticulum unfolded protein response 72
                  regulation of endoplasmic reticulum unfolded protein response 25
                    positive regulation of endoplasmic reticulum unfolded protein response 10
                      positive regulation of ATF6-mediated unfolded protein response 1
                      positive regulation of IRE1-mediated unfolded protein response 2
                      positive regulation of PERK-mediated unfolded protein response 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.