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Term:negative regulation of interleukin-6 secretion
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Accession:GO:1900165 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion.
Synonyms:exact_synonym: down regulation of IL-6 secretion;   down regulation of interleukin-6 secretion;   downregulation of IL-6 secretion;   downregulation of interleukin-6 secretion;   negative regulation of IL-6 secretion
 narrow_synonym: inhibition of IL-6 secretion;   inhibition of interleukin-6 secretion

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negative regulation of interleukin-6 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bank1 B-cell scaffold protein with ankyrin repeats 1 JBrowse link 2 241,273,763 241,545,527 RGD:1624291
G C1qtnf3 C1q and TNF related 3 JBrowse link 2 60,920,160 60,942,586 RGD:1624291
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:1624291
G Cd200 Cd200 molecule JBrowse link 11 60,371,617 60,398,450 RGD:13792521
G Cd200r1 CD200 receptor 1 JBrowse link 11 60,848,161 60,882,470 RGD:13792521
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1600115
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    multicellular organismal process 8629
      cytokine production 781
        negative regulation of cytokine production 270
          negative regulation of interleukin-6 production 50
            negative regulation of interleukin-6 secretion 12
Path 2
Term Annotations click to browse term
  biological_process 18166
    localization 6061
      establishment of localization 4655
        transport 4517
          nitrogen compound transport 2185
            amide transport 1867
              peptide transport 1834
                peptide secretion 687
                  protein secretion 634
                    cytokine secretion 260
                      regulation of cytokine secretion 230
                        negative regulation of cytokine secretion 68
                          negative regulation of interleukin-6 secretion 12
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.