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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of amyloid-beta clearance
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Accession:GO:1900221 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of amyloid-beta clearance.


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regulation of amyloid-beta clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO
IBA
IEA
(PMID:24446231)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:24446231, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Clu clusterin ISO
ISS
IEA
(PMID:24446231)
GO_REF:0000024
GO_REF:0000107
RGD
Alzheimers_University_of_Toronto
Ensembl
PMID:24446231 GO_REF:0000024, GO_REF:0000107 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
negative regulation of amyloid-beta clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 ISO (MGI:6270905|PMID:20876579) RGD PMID:20876579 MGI:6270905 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO (MGI:6270905|PMID:20876579) RGD PMID:20876579 MGI:6270905 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Ifng interferon gamma ISO UniProtKB:P06804|UniProtKB:P15261 (MGI:3697769|PMID:17255335), (MGI:6304699|PMID:29061364) RGD PMID:17255335, PMID:29061364 MGI:3697769, MGI:6304699 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO UniProtKB:P01580|UniProtKB:P06804 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 ISO UniProtKB:Q07954 (PMID:19098903) RGD PMID:19098903 NCBI chr14:80,911,281...80,923,290
Ensembl chr14:80,911,270...80,924,831
JBrowse link
G Myocd myocardin ISO
IEA
(PMID:19098903)
GO_REF:0000107
RGD
Ensembl
PMID:19098903 GO_REF:0000107 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Pla2g3 phospholipase A2, group III ISO (MGI:5912601|PMID:26637123) RGD PMID:26637123 MGI:5912601 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Srf serum response factor ISO (PMID:19098903) RGD PMID:19098903 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tnf tumor necrosis factor ISO UniProtKB:P01580|UniProtKB:P15261 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
positive regulation of amyloid-beta clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 ISS
ISO
GO_REF:0000024
(MGI:5487687|PMID:23467355)
Alzheimers_University_of_Toronto
RGD
PMID:23467355 GO_REF:0000024, MGI:5487687 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Apoe apolipoprotein E ISS
ISO
GO_REF:0000024
(MGI:3621689|PMID:14741101)
UniProt
RGD
PMID:14741101 GO_REF:0000024, MGI:3621689 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Il4 interleukin 4 IDA
ISO
IBA
PMID:18941241
(MGI:6272248|PMID:18941241)
PMID:21873635
RGD PMID:18941241, PMID:18941241, PMID:21873635 MGI:6272248, RGD:13825436, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Lrp1 LDL receptor related protein 1 ISO (MGI:5754651|PMID:26619118) RGD PMID:26619118 MGI:5754651 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 ISO
IEA
UniProtKB:Q14457 (PMID:27853422)
GO_REF:0000107
RGD
Ensembl
PMID:27853422 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 ISO (MGI:5906931|PMID:28802038), (MGI:6254954|PMID:26949937) RGD PMID:26949937, PMID:28802038 MGI:5906931, MGI:6254954 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
G Ttpa alpha tocopherol transfer protein ISO MGI:2386172 (MGI:5912601|PMID:26637123) RGD PMID:26637123 MGI:5912601 NCBI chr 5:34,007,926...34,029,315
Ensembl chr 5:34,007,920...34,028,452
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      regulation of multicellular organismal process 2916
        regulation of amyloid-beta clearance 17
          negative regulation of amyloid-beta clearance 9
          positive regulation of amyloid-beta clearance 7
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of multicellular organismal process 2916
          regulation of amyloid-beta clearance 17
            negative regulation of amyloid-beta clearance 9
            positive regulation of amyloid-beta clearance 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.