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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of NLRP3 inflammasome complex assembly
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Accession:GO:1900226 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
Synonyms:exact_synonym: down regulation of NALP3 inflammasome complex assembly;   down regulation of NLRP3 inflammasome complex assembly;   downregulation of NALP3 inflammasome complex assembly;   downregulation of NLRP3 inflammasome complex assembly;   inhibition of NALP3 inflammasome complex assembly;   negative regulation of NALP3 inflammasome complex assembly
 narrow_synonym: inhibition of NLRP3 inflammasome complex assembly
 related_synonym: down regulation of NLRP3 inflammasome activation;   downregulation of NLRP3 inflammasome activation;   inhibition of NLRP3 inflammasome activation;   negative regulation of NLRP3 inflammasome activation


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negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cptp ceramide-1-phosphate transfer protein ISS
ISO
GO_REF:0000024
(PMID:29164996)
UniProt
RGD
PMID:29164996 GO_REF:0000024 NCBI chr 5:173,314,219...173,318,384
Ensembl chr 5:173,314,228...173,318,313
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO
ISS
(PMID:26347139)
GO_REF:0000024
RGD
UniProt
PMID:26347139 GO_REF:0000024 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,809,531...11,844,184
Ensembl chr10:11,810,926...11,842,482
JBrowse link
G Sirt2 sirtuin 2 ISO
IEA
(MGI:MGI:5488534|PMID:23502856)
GO_REF:0000107
RGD
Ensembl
PMID:23502856 GO_REF:0000107, MGI:MGI:5488534 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    negative regulation of biological process 5686
      negative regulation of cellular process 5156
        negative regulation of cellular component organization 781
          negative regulation of protein-containing complex assembly 157
            negative regulation of NLRP3 inflammasome complex assembly 4
Path 2
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          cellular component assembly 2983
            protein-containing complex assembly 1608
              cellular protein-containing complex assembly 1134
                NLRP3 inflammasome complex assembly 16
                  regulation of NLRP3 inflammasome complex assembly 14
                    negative regulation of NLRP3 inflammasome complex assembly 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.