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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of calcium ion transmembrane transporter activity
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Accession:GO:1901020 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.
Synonyms:exact_synonym: down regulation of calcium ion transmembrane transporter activity;   downregulation of calcium ion transmembrane transporter activity
 narrow_synonym: inhibition of calcium ion transmembrane transporter activity


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negative regulation of calcium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A ISO (PMID:1354394) RGD PMID:1354394 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Pln phospholamban ISO (PMID:19708671)
(PMID:8349590)
RGD PMID:8349590, PMID:19708671 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:15728831 RGD:8554004 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO (PMID:18029012) RGD PMID:18029012 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
negative regulation of ATPase-coupled calcium transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC691807 hypothetical protein LOC691807 ISO (MGI:MGI:6140721|PMID:27923914) RGD PMID:27923914 MGI:MGI:6140721 NCBI chr 2:227,095,487...227,097,247
Ensembl chr 2:227,095,487...227,097,246
JBrowse link
G Mrln myoregulin ISO (MGI:MGI:6140721|PMID:27923914) RGD PMID:27923914 MGI:MGI:6140721 NCBI chr20:19,703,628...19,720,596 JBrowse link
G Pln phospholamban ISO
ISS
(PMID:19708671)
(MGI:MGI:6140721|PMID:27923914), (MGI:MGI:6304509|PMID:30299255)
GO_REF:0000024
RGD
UniProt
PMID:19708671, PMID:27923914, PMID:30299255 GO_REF:0000024, MGI:MGI:6140721, MGI:MGI:6304509 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Sln sarcolipin ISO (MGI:MGI:6140721|PMID:27923914) RGD PMID:27923914 MGI:MGI:6140721 NCBI chr 8:58,431,407...58,435,654
Ensembl chr 8:58,431,407...58,435,654
JBrowse link
G Smim6 small integral membrane protein 6 ISO (MGI:MGI:6140721|PMID:27923914) RGD PMID:27923914 MGI:MGI:6140721 NCBI chr10:104,461,510...104,470,238 JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:24610369) RGD PMID:24610369 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
negative regulation of calcium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 IMP PMID:17442282 BHF-UCL PMID:17442282 RGD:6903343 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 ISO
ISS
IEA
(PMID:31454269)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:31454269 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 ISO
ISS
IEA
(PMID:31454269)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:31454269 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 ISO
ISS
IEA
(PMID:31454269)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:31454269 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Dysf dysferlin ISO MGI:MGI:3055150 (MGI:MGI:5545678|PMID:24302765) RGD PMID:24302765 MGI:MGI:5545678 NCBI chr 4:115,700,942...115,901,873
Ensembl chr 4:115,712,850...115,901,873
JBrowse link
G Rem1 RRAD and GEM like GTPase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:148,108,500...148,116,992
Ensembl chr 3:148,108,539...148,116,991
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 ISO
ISS
(PMID:26164367)
GO_REF:0000024
RGD
UniProt
PMID:26164367 GO_REF:0000024 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 ISS
ISO
GO_REF:0000024
(PMID:26164367)
UniProt
RGD
PMID:26164367 GO_REF:0000024 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 ISO
ISS
(PMID:26164367)
GO_REF:0000024
RGD
UniProt
PMID:26164367 GO_REF:0000024 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Casq2 calsequestrin 2 ISO
IEA
IMP
(PMID:16601229)
(PMID:15041652)
GO_REF:0000107
PMID:17569730
RGD
Ensembl
PMID:15041652, PMID:16601229, PMID:17569730 GO_REF:0000107, RGD:2314601 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Clic2 chloride intracellular channel 2 ISO (PMID:15147738), (PMID:15916532) RGD PMID:15147738, PMID:15916532 NCBI chr20:295,338...310,363
Ensembl chr20:295,250...310,380
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A NOT ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO
IEA
(PMID:17023043), (PMID:22406107)
GO_REF:0000107
RGD
Ensembl
PMID:17023043, PMID:22406107 GO_REF:0000107 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO
IEA
(PMID:11035031)
GO_REF:0000107
RGD
Ensembl
PMID:11035031 GO_REF:0000107 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (MGI:MGI:3708075|PMID:17404231) RGD PMID:17404231 MGI:MGI:3708075 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Sri sorcin ISO (PMID:17699613) RGD PMID:17699613 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983
JBrowse link
negative regulation of store-operated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubqln1 ubiquilin 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:23307288)
Ensembl
UniProt
RGD
PMID:23307288 GO_REF:0000024, GO_REF:0000107 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17960496 RGD:7207144 NCBI chr12:47,185,449...47,209,785
Ensembl chr12:47,179,664...47,209,784
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F ISO (PMID:27226626) RGD PMID:27226626 NCBI chr  X:15,712,709...15,741,135
Ensembl chr  X:15,712,713...15,741,103
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein IMP
IBA
ISO
PMID:21873635
(MGI:MGI:5607190|PMID:24751537)
RGD PMID:24751537, PMID:24751537, PMID:21873635 MGI:MGI:5607190, RGD:10047103, RGD:13792537 NCBI chr 7:12,433,422...12,441,048
Ensembl chr 7:12,433,933...12,441,048
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO (PMID:18292205) RGD PMID:18292205 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Drd2 dopamine receptor D2 ISO
IBA
IDA
(PMID:7921596)
PMID:21873635
PMID:2162345
RGD PMID:7921596, PMID:21873635, PMID:2162345 RGD:13792537, RGD:8554169 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 ISO
IEA
(PMID:7921596)
GO_REF:0000107
RGD
Ensembl
PMID:7921596 GO_REF:0000107 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Gnb5 G protein subunit beta 5 IEA
ISO
ISS
GO_REF:0000107
(PMID:11007869), (PMID:12606627)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11007869, PMID:12606627 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:82,248,951...82,286,493
Ensembl chr 8:82,257,849...82,285,184
JBrowse link
G Gpr35 G protein-coupled receptor 35 ISO (PMID:17940199) RGD PMID:17940199 NCBI chr 9:100,129,428...100,141,269
Ensembl chr 9:100,137,881...100,138,801
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:15937148 RGD:9835002 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of transport 530
        negative regulation of transporter activity 91
          negative regulation of ion transmembrane transporter activity 82
            negative regulation of calcium ion transmembrane transporter activity 38
              negative regulation of ATPase-coupled calcium transmembrane transporter activity 6
              negative regulation of calcium:sodium antiporter activity 1
              negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
              negative regulation of ryanodine-sensitive calcium-release channel activity 12
              negative regulation of store-operated calcium channel activity 1
              negative regulation of voltage-gated calcium channel activity + 18
Path 2
Term Annotations click to browse term
  biological_process 20027
    localization 6496
      establishment of localization 4911
        transport 4759
          ion transport 1787
            cation transport 1283
              metal ion transport 952
                divalent metal ion transport 502
                  calcium ion transport 456
                    regulation of calcium ion transport 296
                      regulation of calcium ion transmembrane transport 179
                        regulation of calcium ion transmembrane transporter activity 91
                          negative regulation of calcium ion transmembrane transporter activity 38
                            negative regulation of ATPase-coupled calcium transmembrane transporter activity 6
                            negative regulation of calcium:sodium antiporter activity 1
                            negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
                            negative regulation of ryanodine-sensitive calcium-release channel activity 12
                            negative regulation of store-operated calcium channel activity 1
                            negative regulation of voltage-gated calcium channel activity + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.