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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of signal transduction in absence of ligand
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Accession:GO:1901099 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.
Synonyms:exact_synonym: down regulation of signal transduction in absence of agonist;   down regulation of signal transduction in absence of ligand;   downregulation of signal transduction in absence of agonist;   downregulation of signal transduction in absence of ligand;   negative regulation of signal transduction in absence of agonist
 narrow_synonym: down regulation of basal signaling;   downregulation of basal signaling;   inhibition of signal transduction in absence of ligand
 broad_synonym: down regulation of non-classical signal transduction;   downregulation of non-classical signal transduction;   negative regulation of non-classical signal transduction


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negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 7 70,360,199 70,377,422 RGD:8553892
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Bcl2l10 BCL2 like 10 JBrowse link 8 82,288,705 82,294,750 RGD:1624291
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:1624291
RGD:1600115
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:1624291
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:1624291
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:1600115
RGD:1624291
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1624291
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
RGD:13792537
G Eya2 EYA transcriptional coactivator and phosphatase 2 JBrowse link 3 162,285,275 162,470,642 RGD:13792537
G Eya3 EYA transcriptional coactivator and phosphatase 3 JBrowse link 5 150,833,754 150,915,390 RGD:13792537
G Eya4 EYA transcriptional coactivator and phosphatase 4 JBrowse link 1 23,237,617 23,611,580 RGD:13792537
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:8553892
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
G Gata1 GATA binding protein 1 JBrowse link X 15,273,937 15,281,759 RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1600115
RGD:1624291
G Gfral GDNF family receptor alpha like JBrowse link 8 83,235,647 83,282,635 RGD:1624291
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Il7 interleukin 7 JBrowse link 2 96,427,884 96,474,979 RGD:1624291
RGD:1600115
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:1624291
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:1624291
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
G Pf4 platelet factor 4 JBrowse link 14 18,848,549 18,849,258 RGD:1624291
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
RGD:1600115
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 JBrowse link 5 9,046,889 9,094,740 RGD:1624291
RGD:1600115
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Stradb STE20 related adaptor beta JBrowse link 9 65,763,437 65,782,513 RGD:1624291
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Unc5b unc-5 netrin receptor B JBrowse link 20 30,339,680 30,406,593 RGD:1600115
RGD:1624291
G Zc3hc1 zinc finger, C3HC-type containing 1 JBrowse link 4 57,684,678 57,706,613 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      negative regulation of signaling 1396
        negative regulation of signal transduction 1232
          negative regulation of signal transduction in absence of ligand 36
            negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 36
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            regulation of signal transduction 2973
              negative regulation of signal transduction 1232
                negative regulation of signal transduction in absence of ligand 36
                  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.