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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of NIK/NF-kappaB signaling
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Accession:GO:1901223 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
Synonyms:narrow_synonym: down regulation of p52-dependent NF-kappaB signaling;   downregulation of p52-dependent NF-kappaB signaling;   inhibition of NIK/NF-kappaB cascade;   inhibition of p52-dependent NF-kappaB signaling;   negative regulation of NF-kappaB import into nucleus;   negative regulation of p52-dependent NF-kappaB signaling
 broad_synonym: down regulation of non-canonical NF-KB signaling;   down regulation of noncanonical NF-kappaB signaling;   down regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway;   downregulation of non-canonical NF-KB signaling;   downregulation of noncanonical NF-kappaB signaling;   downregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway;   inhibition of non-canonical NF-KB signaling;   inhibition of noncanonical NF-kappaB signaling;   inhibition of noncanonical nuclear factor kappaB (NF-kappaB) pathway;   negative regulation of non-canonical NF-KB signaling;   negative regulation of noncanonical NF-kappaB signaling;   negative regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway
 related_synonym: down regulation of NIK/NF-kappaB cascade;   downregulation of NIK/NF-kappaB cascade;   negative regulation of NIK/NF-kappaB cascade
 alt_id: GO:0042347


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negative regulation of NIK/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgrg3 adhesion G protein-coupled receptor G3 JBrowse link 19 10,392,001 10,422,606 RGD:1624291
G Adipor1 adiponectin receptor 1 JBrowse link 13 51,240,470 51,260,233 RGD:1624291
G C1qtnf3 C1q and TNF related 3 JBrowse link 2 60,920,160 60,942,586 RGD:1624291
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:13792556
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:1600115
RGD:1624291
G Cpne1 copine 1 JBrowse link 3
3
151,617,733
152,150,143
151,625,448
152,192,936
RGD:1624291
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:1600115
RGD:1624291
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
G Fbxw11 F-box and WD repeat domain containing 11 JBrowse link 10 17,542,374 17,640,718 RGD:1624291
G Hdac7 histone deacetylase 7 JBrowse link 7 139,280,396 139,319,108 RGD:1600115
RGD:1624291
G Litaf lipopolysaccharide-induced TNF factor JBrowse link 10 4,753,546 4,763,272 RGD:1624291
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 1 162,369,801 162,376,024 RGD:11040458
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
G Nlrp12 NLR family, pyrin domain containing 12 JBrowse link 1 64,506,750 64,543,908 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
RGD:13792537
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A JBrowse link 6 94,433,658 94,484,979 RGD:1600115
RGD:1624291
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B JBrowse link 6 8,219,385 8,280,127 RGD:1600115
RGD:1624291
G Rassf2 Ras association domain family member 2 JBrowse link 3 124,574,088 124,610,267 RGD:1624291
RGD:1600115
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:1624291
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:1624291
G Tspan6 tetraspanin 6 JBrowse link X 104,719,930 104,729,606 RGD:1624291
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats JBrowse link 8 65,686,586 65,774,940 RGD:1624291
RGD:13792537
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    negative regulation of biological process 5617
      negative regulation of signaling 1396
        negative regulation of signal transduction 1232
          negative regulation of intracellular signal transduction 546
            negative regulation of NIK/NF-kappaB signaling 23
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            intracellular signal transduction 2597
              NIK/NF-kappaB signaling 140
                regulation of NIK/NF-kappaB signaling 131
                  negative regulation of NIK/NF-kappaB signaling 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.