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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of histone H2A K63-linked ubiquitination
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Accession:GO:1901315 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.
Synonyms:exact_synonym: down regulation of histone H2A K63-linked ubiquitination;   downregulation of histone H2A K63-linked ubiquitination
 narrow_synonym: inhibition of histone H2A K63-linked ubiquitination


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negative regulation of histone H2A K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 ISO
ISS
IBA
(PMID:20725033)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:20725033, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:222,451,674...222,459,952
Ensembl chr 1:222,451,674...222,459,952
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:22884692)
Ensembl
UniProt
RGD
PMID:22884692, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 9:92,305,059...92,435,388
Ensembl chr 9:92,305,051...92,435,365
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:22884692)
Ensembl
UniProt
RGD
PMID:22884692, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 7:76,789,110...76,835,517
NCBI chr 7:76,839,661...76,907,441
Ensembl chr 7:76,789,531...76,853,840
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      negative regulation of metabolic process 3316
        negative regulation of cellular metabolic process 2780
          negative regulation of cellular protein metabolic process 1137
            negative regulation of protein modification process 638
              negative regulation of histone modification 53
                negative regulation of histone ubiquitination 4
                  negative regulation of histone H2A K63-linked ubiquitination 4
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      organic substance metabolic process 11639
        macromolecule metabolic process 10084
          protein metabolic process 6217
            protein modification process 3939
              cellular protein modification process 3939
                protein modification by small protein conjugation or removal 954
                  protein modification by small protein conjugation 818
                    protein ubiquitination 769
                      protein polyubiquitination 240
                        protein K63-linked ubiquitination 58
                          regulation of protein K63-linked ubiquitination 12
                            regulation of histone H2A K63-linked ubiquitination 4
                              negative regulation of histone H2A K63-linked ubiquitination 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.