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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of histone H2A K63-linked ubiquitination
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Accession:GO:1901315 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.
Synonyms:exact_synonym: down regulation of histone H2A K63-linked ubiquitination;   downregulation of histone H2A K63-linked ubiquitination
 narrow_synonym: inhibition of histone H2A K63-linked ubiquitination


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negative regulation of histone H2A K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 ISO (PMID:20725033) UniProtKB PMID:20725033 NCBI chr11:59,342,820...59,355,386
Ensembl chr11:62,690,542...62,706,542
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G TRIP12 thyroid hormone receptor interactor 12 ISO (PMID:22884692) UniProtKB PMID:22884692 NCBI chr2B:117,013,343...117,175,296
Ensembl chr2B:235,820,182...235,979,780
JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ISO (PMID:22884692) UniProtKB PMID:22884692 NCBI chr 8:98,904,557...99,064,121
Ensembl chr 8:101,067,435...101,224,913
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    cellular process 11665
      negative regulation of cellular process 4407
        negative regulation of cellular component organization 685
          negative regulation of chromatin organization 53
            negative regulation of histone modification 48
              negative regulation of histone ubiquitination 3
                negative regulation of histone H2A K63-linked ubiquitination 3
Path 2
Term Annotations click to browse term
  biological_process 12561
    metabolic process 7977
      organic substance metabolic process 7668
        macromolecule metabolic process 6621
          protein metabolic process 4007
            protein modification process 2973
              cellular protein modification process 2973
                protein modification by small protein conjugation or removal 662
                  protein modification by small protein conjugation 566
                    protein ubiquitination 511
                      protein polyubiquitination 184
                        protein K63-linked ubiquitination 49
                          regulation of protein K63-linked ubiquitination 11
                            regulation of histone H2A K63-linked ubiquitination 3
                              negative regulation of histone H2A K63-linked ubiquitination 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.