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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transforming growth factor beta activation
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Accession:GO:1901389 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation.
Synonyms:exact_synonym: down regulation of L-TGF-beta activation;   down regulation of TGF-B activation;   down regulation of TGF-beta activation;   down regulation of TGFB activation;   down regulation of TGFbeta activation;   down regulation of latent TGF-beta activation;   down regulation of transforming growth factor beta activation;   downregulation of L-TGF-beta activation;   downregulation of TGF-B activation;   downregulation of TGF-beta activation;   downregulation of TGFB activation;   downregulation of TGFbeta activation;   downregulation of latent TGF-beta activation;   downregulation of transforming growth factor beta activation;   inhibition of L-TGF-beta activation;   inhibition of TGF-B activation;   inhibition of TGF-beta activation;   inhibition of TGFB activation;   inhibition of TGFbeta activation;   inhibition of latent TGF-beta activation;   negative regulation of L-TGF-beta activation;   negative regulation of TGF-B activation;   negative regulation of TGF-beta activation;   negative regulation of TGFB activation;   negative regulation of TGFbeta activation;   negative regulation of latent TGF-beta activation
 narrow_synonym: inhibition of transforming growth factor beta activation


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negative regulation of transforming growth factor beta activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B ISO RGD DOI:10.1016/j.procbio.2011.10.027 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO
ISS
(PMID:20599762)
GO_REF:0000024
RGD
UniProt
PMID:20599762 GO_REF:0000024 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
negative regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    multicellular organismal process 9046
      transforming growth factor beta activation 11
        negative regulation of transforming growth factor beta activation 3
          negative regulation of transforming growth factor beta1 activation 1
          negative regulation of transforming growth factor beta2 activation 0
          negative regulation of transforming growth factor beta3 activation 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        macromolecule metabolic process 10086
          gene expression 6304
            cytokine production 764
              regulation of cytokine production 753
                regulation of transforming growth factor beta production 42
                  negative regulation of transforming growth factor beta production 15
                    negative regulation of transforming growth factor beta activation 3
                      negative regulation of transforming growth factor beta1 activation 1
                      negative regulation of transforming growth factor beta2 activation 0
                      negative regulation of transforming growth factor beta3 activation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.