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ONTOLOGY REPORT - ANNOTATIONS


Term:fatty acid derivative biosynthetic process
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Accession:GO:1901570 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of fatty acid derivative.
Synonyms:exact_synonym: fatty acid derivative anabolism;   fatty acid derivative biosynthesis;   fatty acid derivative formation;   fatty acid derivative synthesis


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cyclooxygenase pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:1624291
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:1624291
RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1600115
RGD:1624291
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:2311353
fatty acid primary amide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pam peptidylglycine alpha-amidating monooxygenase JBrowse link 9 111,028,543 111,177,588 RGD:14390048
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcdh glutaryl-CoA dehydrogenase JBrowse link 19 26,000,497 26,006,970 RGD:1598697
RGD:13792537
icosanoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:5509794
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:14402444
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 JBrowse link 1 263,778,510 263,803,166 RGD:14402444
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:1624291
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 JBrowse link 5 134,492,734 134,507,158 RGD:1625451
RGD:13792537
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 JBrowse link 5 134,196,910 134,207,888 RGD:1625451
RGD:13792537
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 JBrowse link 5 134,468,666 134,484,851 RGD:1625451
RGD:13792537
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 JBrowse link 5 133,978,953 134,008,255 RGD:13792537
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1624291
ketone body biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link 5 154,294,841 154,308,582 RGD:1599519
RGD:13792537
RGD:1624291
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 JBrowse link 8 83,069,837 83,204,778 RGD:1600115
RGD:13792537
RGD:1624291
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:728598
RGD:1624291
RGD:2326121
G Slc27a5 solute carrier family 27 member 5 JBrowse link 1 65,576,599 65,587,192 RGD:1624291
RGD:13792537
leukotriene A4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:1624291
RGD:1600115
leukotriene biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:632194
RGD:1624291
RGD:1600115
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link 12 6,854,930 6,879,112 RGD:69749
RGD:13792537
RGD:1624291
RGD:2313889
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1624291
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:1600115
RGD:13792537
RGD:1624291
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:724432
RGD:13792537
RGD:2302289
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link 2 140,708,396 140,727,381 RGD:1624291
RGD:13792537
G Mgst3 microsomal glutathione S-transferase 3 JBrowse link 13 85,601,499 85,622,392 RGD:1624291
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1624291
RGD:1600115
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:2303037
RGD:1624291
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1624291
RGD:1600115
leukotriene D4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07044631.2 RGD:13792537
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:1624291
G Ggt5 gamma-glutamyltransferase 5 JBrowse link 20 13,988,444 14,001,296 RGD:1624291
RGD:13792537
lipoxin A4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:1624291
RGD:1600115
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:1624291
RGD:1600115
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:1600115
RGD:1624291
lipoxin B4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:1624291
RGD:1600115
lipoxin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:1600115
RGD:1624291
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:2312800
RGD:13792537
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:2312800
G Acsl5 acyl-CoA synthetase long-chain family member 5 JBrowse link 1 276,240,703 276,290,012 RGD:2312800
RGD:13792537
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:2312800
RGD:13792537
G Elovl1 ELOVL fatty acid elongase 1 JBrowse link 5 137,255,868 137,260,486 RGD:1600115
G Elovl3 ELOVL fatty acid elongase 3 JBrowse link 1 265,883,353 265,887,181 RGD:1600115
G Elovl4 ELOVL fatty acid elongase 4 JBrowse link 8 91,310,690 91,338,625 RGD:1600115
G Elovl5 ELOVL fatty acid elongase 5 JBrowse link 8 85,220,941 85,287,449 RGD:1600115
G Elovl6 ELOVL fatty acid elongase 6 JBrowse link 2 234,187,490 234,296,124 RGD:1600115
G Elovl7 ELOVL fatty acid elongase 7 JBrowse link 2 40,373,211 40,386,643 RGD:1600115
G LOC102549542 elongation of very long chain fatty acids protein 6-like JBrowse link 2 234,375,172 234,486,639 RGD:1600115
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:2306959
RGD:13792537
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:2300349
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:2300349
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304243
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642461
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
propionyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034131.1 RGD:13792537
G AABR07054614.1 RGD:1600115
RGD:13792537
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:1600115
RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1624291
RGD:1600115
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:68838
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1624291
RGD:1600115
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 6 64,224,870 64,288,465 RGD:1624291
G Prxl2b peroxiredoxin like 2B JBrowse link 5 172,304,799 172,307,402 RGD:1624291
RGD:8552775
RGD:1600115
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:8553429
RGD:1624291
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:67929
RGD:13792537
RGD:1624291
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:5688071
RGD:13792537
RGD:1600115
RGD:1624291
G Ptges3l1 prostaglandin E synthase 3-like 1 JBrowse link X 45,410,545 45,419,817 RGD:13792537
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:727270
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8693629
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:2300259
RGD:1600115
RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300259
RGD:1624291
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:1624291
regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:1624291
wax biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Awat2 acyl-CoA wax alcohol acyltransferase 2 JBrowse link X 70,224,761 70,233,021 RGD:1624291
G Far1 fatty acyl CoA reductase 1 JBrowse link 1 178,351,674 178,412,838 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      organic substance metabolic process 11495
        fatty acid derivative metabolic process 169
          fatty acid derivative biosynthetic process 76
            fatty acid primary amide biosynthetic process 1
            fatty-acyl-CoA biosynthetic process + 13
            icosanoid biosynthetic process + 56
            ketone body biosynthetic process + 4
            wax biosynthetic process + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.