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ONTOLOGY REPORT - ANNOTATIONS


Term:alpha-amino acid catabolic process
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Accession:GO:1901606 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.
Synonyms:exact_synonym: alpha-amino acid breakdown;   alpha-amino acid catabolism;   alpha-amino acid degradation


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4-hydroxyproline catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 JBrowse link 1 261,291,742 261,319,743 RGD:1624291
arginine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:1624291
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 20 5,049,260 5,052,573 RGD:1600115
G Fah fumarylacetoacetate hydrolase JBrowse link 1 146,713,663 146,736,339 RGD:1624291
RGD:1600115
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:8553334
RGD:13792537
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1624291
RGD:13792537
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1600115
RGD:13792537
RGD:1624291
arginine catabolic process to glutamate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:13792537
arginine catabolic process to ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:8693655
RGD:13792537
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1358311
RGD:13792537
RGD:8693655
arginine catabolic process to proline via ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:13792537
arginine deiminase pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Padi3 peptidyl arginine deiminase 3 JBrowse link 5 159,309,000 159,336,429 RGD:69926
asparagine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspg asparaginase JBrowse link 6 136,682,279 136,701,673 RGD:13792537
asparagine catabolic process via L-aspartate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asrgl1 asparaginase and isoaspartyl peptidase 1 JBrowse link 1 225,309,737 225,329,743 RGD:1299508
RGD:13792537
RGD:1624291
aspartate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddo D-aspartate oxidase JBrowse link 20 48,739,812 48,758,958 RGD:1624291
RGD:13792537
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1624291
RGD:13792537
D-alanine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:1600115
RGD:13792537
RGD:1624291
D-amino acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddo D-aspartate oxidase JBrowse link 20 48,739,812 48,758,958 RGD:1624291
D-serine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:1600115
RGD:13792537
RGD:1624291
glutamate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1601355
RGD:13792537
RGD:1624291
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
RGD:13504861
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1624291
RGD:13504861
glutamate catabolic process to aspartate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1624291
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adhfe1 alcohol dehydrogenase, iron containing, 1 JBrowse link 5 9,403,194 9,429,783 RGD:1600115
RGD:1624291
glutamate decarboxylation to succinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:1625237
glutamine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:728510
RGD:13792537
RGD:1624291
RGD:1600115
G Gls2 glutaminase 2 JBrowse link 7 2,605,679 2,621,853 RGD:13792537
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:633710
glycine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gldc glycine decarboxylase JBrowse link 1 248,295,140 248,377,122 RGD:1624291
glycine decarboxylation via glycine cleavage system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07007134.1 RGD:1600115
G AABR07067762.1 RGD:1600115
G Amt aminomethyltransferase JBrowse link 8 117,068,388 117,078,633 RGD:1624291
RGD:13792537
G Gcsh glycine cleavage system protein H JBrowse link 19 49,522,054 49,532,811 RGD:1598699
G Gldc glycine decarboxylase JBrowse link 1 248,295,140 248,377,122 RGD:1642728
RGD:13792537
histidine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amdhd1 amidohydrolase domain containing 1 JBrowse link 7 34,362,635 34,406,282 RGD:13792537
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:1624291
RGD:13792537
G Hdc histidine decarboxylase JBrowse link 3 119,057,524 119,075,599 RGD:1624291
RGD:1600115
G Uroc1 urocanate hydratase 1 JBrowse link 4 122,244,744 122,276,357 RGD:1624291
RGD:13792537
histidine catabolic process to glutamate and formamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amdhd1 amidohydrolase domain containing 1 JBrowse link 7 34,362,635 34,406,282 RGD:1600115
G Ftcd formimidoyltransferase cyclodeaminase JBrowse link 20 12,806,957 12,820,466 RGD:1600115
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:1600115
histidine catabolic process to glutamate and formate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ftcd formimidoyltransferase cyclodeaminase JBrowse link 20 12,806,957 12,820,466 RGD:1600115
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:1600115
homocysteine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blmh bleomycin hydrolase JBrowse link 10 63,197,367 63,240,447 RGD:13792537
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1600115
RGD:1624291
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 1 37,743,089 37,774,485 RGD:1624291
isoleucine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1582175
RGD:1600115
RGD:1624291
L-alanine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase JBrowse link 9 100,281,339 100,291,292 RGD:1624291
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:1600115
L-alanine catabolic process, by transamination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:1624291
RGD:13792537
L-cysteine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase JBrowse link 9 100,281,339 100,291,292 RGD:1624291
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1624291
G Cdo1 cysteine dioxygenase type 1 JBrowse link 18 40,702,027 40,716,901 RGD:2301357
RGD:13792537
L-cysteine catabolic process to hypotaurine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csad cysteine sulfinic acid decarboxylase JBrowse link 7 143,781,520 143,810,880 RGD:13800536
L-cysteine catabolic process to taurine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csad cysteine sulfinic acid decarboxylase JBrowse link 7 143,781,520 143,810,880 RGD:13800536
L-kynurenine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kyat1 kynurenine aminotransferase 1 JBrowse link 3 8,752,289 8,785,617 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1600115
L-lysine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aass aminoadipate-semialdehyde synthase JBrowse link 4 50,152,005 50,208,935 RGD:1624291
RGD:1600115
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pipox pipecolic acid and sarcosine oxidase JBrowse link 10 64,951,986 64,964,865 RGD:1624291
RGD:13792537
L-lysine catabolic process to acetyl-CoA via saccharopine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadat aminoadipate aminotransferase JBrowse link 16 32,832,001 32,868,680 RGD:1600115
G Aass aminoadipate-semialdehyde synthase JBrowse link 4 50,152,005 50,208,935 RGD:1600115
G Dlst dihydrolipoamide S-succinyltransferase JBrowse link 6 108,936,534 108,961,322 RGD:1600115
L-phenylalanine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fah fumarylacetoacetate hydrolase JBrowse link 1 146,713,663 146,736,339 RGD:1600115
RGD:13792537
G Gstz1 glutathione S-transferase zeta 1 JBrowse link 6 111,176,798 111,187,246 RGD:1600115
RGD:13792537
G Hgd homogentisate 1, 2-dioxygenase JBrowse link 11 65,983,221 66,034,555 RGD:13792537
G Hpd 4-hydroxyphenylpyruvate dioxygenase JBrowse link 12 38,828,606 38,839,956 RGD:1600115
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:1600115
G Qdpr quinoid dihydropteridine reductase JBrowse link 14 70,164,682 70,178,284 RGD:5128604
RGD:13792537
G Tat tyrosine aminotransferase JBrowse link 19 41,675,639 41,686,195 RGD:1600115
L-serine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1624291
G Sds serine dehydratase JBrowse link 12 41,620,429 41,627,741 RGD:1600115
RGD:13792537
RGD:1624291
G Sdsl serine dehydratase-like JBrowse link 12 41,636,994 41,647,205 RGD:13792537
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:13792537
leucine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Auh AU RNA binding methylglutaconyl-CoA hydratase JBrowse link 17 12,310,178 12,405,224 RGD:1600115
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link 5 154,294,841 154,308,582 RGD:13792537
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 JBrowse link 8 83,069,837 83,204,778 RGD:13792537
G Ivd isovaleryl-CoA dehydrogenase JBrowse link 3 110,669,355 110,689,789 RGD:1600115
RGD:1624291
RGD:8554099
G Mccc1 methylcrotonoyl-CoA carboxylase 1 JBrowse link 2 122,550,777 122,690,540 RGD:1600115
G Mccc2 methylcrotonoyl-CoA carboxylase 2 JBrowse link 2 30,175,017 30,246,028 RGD:1600115
RGD:13792537
methionine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mat1a methionine adenosyltransferase 1A JBrowse link 16 18,690,649 18,709,135 RGD:1600115
RGD:1624291
negative regulation of arginine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
ornithine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Otc ornithine carbamoyltransferase JBrowse link X 13,524,804 13,601,074 RGD:1624291
proline catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:1600115
RGD:13792537
RGD:1624291
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:1600115
proline catabolic process to glutamate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 JBrowse link 5 158,090,238 158,115,725 RGD:1600115
G Iffo2 intermediate filament family orphan 2 JBrowse link 5 158,042,587 158,083,311 RGD:1600115
G Prodh1 proline dehydrogenase 1 JBrowse link 11 87,058,478 87,075,785 RGD:13792537
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:13792537
G Tas1r2 taste 1 receptor member 2 JBrowse link 5 158,119,894 158,135,733 RGD:1600115
S-adenosylhomocysteine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahcy adenosylhomocysteinase JBrowse link 3 150,587,833 150,603,057 RGD:730275
RGD:1624291
sarcosine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sardh sarcosine dehydrogenase JBrowse link 3 5,737,203 5,802,153 RGD:13792537
selenocysteine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scly selenocysteine lyase JBrowse link 9 98,438,408 98,459,075 RGD:12793035
serine family amino acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Thnsl2 threonine synthase-like 2 JBrowse link 4 98,976,559 98,997,187 RGD:1624291
RGD:13792537
threonine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcat glycine C-acetyltransferase JBrowse link 7 120,263,068 120,269,365 RGD:1600115
G LOC688286 similar to threonine aldolase 1 JBrowse link 10 106,877,585 106,883,706 RGD:13792537
G Sds serine dehydratase JBrowse link 12 41,620,429 41,627,741 RGD:13792537
G Sdsl serine dehydratase-like JBrowse link 12 41,636,994 41,647,205 RGD:13792537
G Tdh L-threonine dehydrogenase JBrowse link 15 46,667,926 46,682,752 RGD:1624291
RGD:13792537
tryptophan catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:70243
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:1600115
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1624291
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:2303721
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2303721
RGD:13792537
tryptophan catabolic process to kynurenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1624291
RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:2290190
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2290543
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:1600115
RGD:13792537
RGD:1624291
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:13792537
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:1600115
RGD:1624291
tyrosine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fah fumarylacetoacetate hydrolase JBrowse link 1 146,713,663 146,736,339 RGD:13792537
RGD:1600115
G Gstz1 glutathione S-transferase zeta 1 JBrowse link 6 111,176,798 111,187,246 RGD:1600115
G Hpd 4-hydroxyphenylpyruvate dioxygenase JBrowse link 12 38,828,606 38,839,956 RGD:632936
RGD:13792537
RGD:8554707
G Tat tyrosine aminotransferase JBrowse link 19 41,675,639 41,686,195 RGD:1624291
RGD:1600115
valine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 JBrowse link 6 108,146,552 108,167,185 RGD:1599052
RGD:13792537
RGD:1600115
RGD:1624291
G Hibadh 3-hydroxyisobutyrate dehydrogenase JBrowse link 4 82,604,369 82,702,429 RGD:1600115
RGD:13792537
RGD:1624291
G Hibch 3-hydroxyisobutyryl-CoA hydrolase JBrowse link 9 53,446,185 53,526,727 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19404
    metabolic process 11621
      primary metabolic process 10463
        cellular amino acid metabolic process 267
          alpha-amino acid metabolic process 193
            alpha-amino acid catabolic process 90
              1-aminocyclopropane-1-carboxylate catabolic process 0
              3-cyano-L-alanine catabolic process 0
              4-hydroxyproline catabolic process 1
              D-amino acid catabolic process + 2
              L-kynurenine catabolic process 2
              N(omega),N(omega)-dimethyl-L-arginine catabolic process 0
              N(omega)-methyl-L-arginine catabolic process 0
              N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process + 0
              S-adenosylhomocysteine catabolic process 1
              aspartate family amino acid catabolic process + 15
              citrulline catabolic process 0
              discadenine catabolic process 0
              erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process + 7
              glutamine family amino acid catabolic process + 27
              histidine catabolic process + 5
              homocysteine catabolic process 3
              isoleucine catabolic process 2
              leucine catabolic process + 6
              nopaline catabolic process + 0
              ornithine catabolic process + 1
              phosphoarginine catabolic process 0
              pyruvate family amino acid catabolic process + 4
              sarcosine catabolic process 1
              serine family amino acid catabolic process + 16
              stachydrine catabolic process 0
              tryptophan catabolic process + 8
              tyrosine catabolic process + 4
              valine catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 19404
    metabolic process 11621
      organic substance metabolic process 11012
        organic acid metabolic process 1041
          oxoacid metabolic process 1014
            carboxylic acid metabolic process 970
              carboxylic acid catabolic process 233
                cellular amino acid catabolic process 104
                  alpha-amino acid catabolic process 90
                    1-aminocyclopropane-1-carboxylate catabolic process 0
                    3-cyano-L-alanine catabolic process 0
                    4-hydroxyproline catabolic process 1
                    D-amino acid catabolic process + 2
                    L-kynurenine catabolic process 2
                    N(omega),N(omega)-dimethyl-L-arginine catabolic process 0
                    N(omega)-methyl-L-arginine catabolic process 0
                    N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process + 0
                    S-adenosylhomocysteine catabolic process 1
                    aspartate family amino acid catabolic process + 15
                    citrulline catabolic process 0
                    discadenine catabolic process 0
                    erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process + 7
                    glutamine family amino acid catabolic process + 27
                    histidine catabolic process + 5
                    homocysteine catabolic process 3
                    isoleucine catabolic process 2
                    leucine catabolic process + 6
                    nopaline catabolic process + 0
                    ornithine catabolic process + 1
                    phosphoarginine catabolic process 0
                    pyruvate family amino acid catabolic process + 4
                    sarcosine catabolic process 1
                    serine family amino acid catabolic process + 16
                    stachydrine catabolic process 0
                    tryptophan catabolic process + 8
                    tyrosine catabolic process + 4
                    valine catabolic process + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.