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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of signal transduction by p53 class mediator
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Accession:GO:1901796 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.


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regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bop1 BOP1 ribosomal biogenesis factor JBrowse link NW_004955454 2,882,694 2,907,177 RGD:9068941
G Hipk4 homeodomain interacting protein kinase 4 JBrowse link NW_004955578 876,022 884,098 RGD:9068941
G Nop2 NOP2 nucleolar protein JBrowse link NW_004955413 4,180,463 4,190,827 RGD:9068941
G Nop53 NOP53 ribosome biogenesis factor JBrowse link NW_004955574 1,505,997 1,514,680 RGD:9068941
G Pak1ip1 PAK1 interacting protein 1 JBrowse link NW_004955465 3,635,004 3,644,638 RGD:9068941
G Prmt6 protein arginine methyltransferase 6 JBrowse link NW_004955435 10,816,787 10,818,047 RGD:9068941
G Rpf2 ribosome production factor 2 homolog JBrowse link NW_004955411 35,627,127 35,663,903 RGD:9068941
G Rpl11 ribosomal protein L11 JBrowse link NW_004955452 3,626,609 3,630,911 RGD:9068941
G Rpl5 ribosomal protein L5 JBrowse link NW_004955423 1,748,809 1,758,622 RGD:9068941
G Rrs1 ribosome biogenesis regulator 1 homolog JBrowse link NW_004955444 12,740,172 12,751,674 RGD:9068941
G Trim24 tripartite motif containing 24 JBrowse link NW_004955494 4,308,924 4,421,588 RGD:9068941
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd44 CD44 molecule (Indian blood group) JBrowse link NW_004955422 11,106,061 11,189,951 RGD:9068941
G Cd74 CD74 molecule JBrowse link NW_004955415 4,129,151 4,138,336 RGD:9068941
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link NW_004955407 36,456,628 36,588,940 RGD:9068941
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link NW_004955406 42,190,043 42,199,323 RGD:9068941
G Kdm1a lysine demethylase 1A JBrowse link NW_004955452 3,044,042 3,104,650 RGD:9068941
G Marchf7 membrane associated ring-CH-type finger 7 JBrowse link NW_004955449 13,834,561 13,875,864 RGD:9068941
G Mdm2 MDM2 proto-oncogene JBrowse link NW_004955458 15,264,028 15,287,290 RGD:9068941
G Mif macrophage migration inhibitory factor JBrowse link NW_004955455 8,367,566 8,368,460 RGD:9068941
G Psmd10 proteasome 26S subunit, non-ATPase 10 JBrowse link NW_004955490 7,825,202 7,832,347 RGD:9068941
G Pttg1ip PTTG1 interacting protein JBrowse link NW_004955407 41,753,855 41,769,107 RGD:9068941
G Senp2 SUMO specific peptidase 2 JBrowse link NW_004955420 21,969,537 22,005,094 RGD:9068941
G Sirt1 sirtuin 1 JBrowse link NW_004955425 20,280,725 20,307,663 RGD:9068941
G Snai1 snail family transcriptional repressor 1 JBrowse link NW_004955445 8,232,084 8,237,893 RGD:9068941
G Snai2 snail family transcriptional repressor 2 JBrowse link NW_004955454 8,759,860 8,763,603 RGD:9068941
G Twist1 twist family bHLH transcription factor 1 JBrowse link NW_004955410 22,003,981 22,005,483 RGD:9068941
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcbp4 poly(rC) binding protein 4 JBrowse link NW_004955532 3,604,720 3,615,112 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc10 armadillo repeat containing 10 JBrowse link NW_004955410 8,203,127 8,217,421 RGD:9068941
G Cep63 centrosomal protein 63 JBrowse link NW_004955501 4,032,281 4,095,990 RGD:9068941
G Mdm2 MDM2 proto-oncogene JBrowse link NW_004955458 15,264,028 15,287,290 RGD:9068941
G Mdm4 MDM4 regulator of p53 JBrowse link NW_004955406 40,346,617 40,387,977 RGD:9068941
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link NW_004955439 18,664,230 19,953,358 RGD:9068941
G Pttg1ip PTTG1 interacting protein JBrowse link NW_004955407 41,753,855 41,769,107 RGD:9068941
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link NW_004955417 26,949,686 26,976,976 RGD:9068941
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link NW_004955442 129,106 166,258 RGD:9068941
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link NW_004955423 7,393,186 7,414,199 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family AAA domain containing 5 JBrowse link NW_004955481 6,986,128 7,031,113 RGD:9068941
G Bcl2l12 BCL2 like 12 JBrowse link NW_004955559 1,217,797 1,224,875 RGD:9068941
G Cd44 CD44 molecule (Indian blood group) JBrowse link NW_004955422 11,106,061 11,189,951 RGD:9068941
G Cd74 CD74 molecule JBrowse link NW_004955415 4,129,151 4,138,336 RGD:9068941
G Ell3 elongation factor for RNA polymerase II 3 JBrowse link NW_004955416 10,223,213 10,226,978 RGD:9068941
G Kdm1a lysine demethylase 1A JBrowse link NW_004955452 3,044,042 3,104,650 RGD:9068941
G Marchf7 membrane associated ring-CH-type finger 7 JBrowse link NW_004955449 13,834,561 13,875,864 RGD:9068941
G Mif macrophage migration inhibitory factor JBrowse link NW_004955455 8,367,566 8,368,460 RGD:9068941
G Muc1 mucin 1, cell surface associated JBrowse link NW_004955545 1,657,728 1,662,112 RGD:9068941
G Sirt1 sirtuin 1 JBrowse link NW_004955425 20,280,725 20,307,663 RGD:9068941
G Triap1 TP53 regulated inhibitor of apoptosis 1 JBrowse link NW_004955455 11,195,399 11,198,402 RGD:9068941
G Znf385a zinc finger protein 385A JBrowse link NW_004955458 1,610,245 1,631,639 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb2 bradykinin receptor B2 JBrowse link NW_004955438 16,514,300 16,537,160 RGD:9068941
negative regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ell3 elongation factor for RNA polymerase II 3 JBrowse link NW_004955416 10,223,213 10,226,978 RGD:9068941
G Mdm2 MDM2 proto-oncogene JBrowse link NW_004955458 15,264,028 15,287,290 RGD:9068941
G Nop53 NOP53 ribosome biogenesis factor JBrowse link NW_004955574 1,505,997 1,514,680 RGD:9068941
G Rffl ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link NW_004955481 9,718,369 9,788,048 RGD:9068941
G Rnf34 ring finger protein 34 JBrowse link NW_004955482 6,889,112 6,905,139 RGD:9068941
G Senp2 SUMO specific peptidase 2 JBrowse link NW_004955420 21,969,537 22,005,094 RGD:9068941
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd1 ankyrin repeat domain 1 JBrowse link NW_004955425 2,258,554 2,267,699 RGD:9068941
G Atm ATM serine/threonine kinase JBrowse link NW_004955412 10,422,753 10,531,406 RGD:9068941
G Atr ATR serine/threonine kinase JBrowse link NW_004955508 3,337,036 3,440,313 RGD:9068941
G Ddx5 DEAD-box helicase 5 JBrowse link NW_004955478 7,367,049 7,375,043 RGD:9068941
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 JBrowse link NW_004955465 5,878,055 5,895,232 RGD:9068941
G Hic1 HIC ZBTB transcriptional repressor 1 JBrowse link NW_004955481 1,179,015 1,182,936 RGD:9068941
G Pla2r1 phospholipase A2 receptor 1 JBrowse link NW_004955449 13,542,458 13,653,907 RGD:9068941
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link NW_004955402 44,005,517 44,010,722 RGD:9068941
G Spred1 sprouty related EVH1 domain containing 1 JBrowse link NW_004955416 5,288,779 5,376,861 RGD:9068941
G Spred2 sprouty related EVH1 domain containing 2 JBrowse link NW_004955424 19,133,568 19,250,118 RGD:9068941
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpl26 ribosomal protein L26 JBrowse link NW_004955467 8,519,760 8,525,514 RGD:9068941
G Znf385a zinc finger protein 385A JBrowse link NW_004955458 1,610,245 1,631,639 RGD:9068941
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msx1 msh homeobox 1 JBrowse link NW_004955514 4,923,552 4,927,471 RGD:9068941
G Rpl11 ribosomal protein L11 JBrowse link NW_004955452 3,626,609 3,630,911 RGD:9068941
G Rps7 ribosomal protein S7 JBrowse link NW_004955487 3,793,168 3,798,007 RGD:9068941
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link NW_004955423 7,393,186 7,414,199 RGD:9068941
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpl26 ribosomal protein L26 JBrowse link NW_004955467 8,519,760 8,525,514 RGD:9068941
G Steap3 STEAP3 metalloreductase JBrowse link NW_004955459 10,441,906 10,485,235 RGD:9068941
G Tp73 tumor protein p73 JBrowse link NW_004955486 7,914,608 7,961,992 RGD:9068941
positive regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link NW_004955451 13,160,811 13,170,012 RGD:9068941
G Chd5 chromodomain helicase DNA binding protein 5 JBrowse link NW_004955486 6,320,380 6,369,020 RGD:9068941
G Rpl11 ribosomal protein L11 JBrowse link NW_004955452 3,626,609 3,630,911 RGD:9068941
G Rpl23 ribosomal protein L23 JBrowse link NW_004955451 13,892,880 13,898,079 RGD:9068941
regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kmt5a lysine methyltransferase 5A JBrowse link NW_004955482 5,488,151 5,500,764 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Smyd2 SET and MYND domain containing 2 JBrowse link NW_004955406 3,467,123 3,509,156 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004955467 9,241,391 9,256,716 RGD:9068941
G Zmpste24 zinc metallopeptidase STE24 JBrowse link NW_004955537 82,724 134,609 RGD:9068941
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd2 ankyrin repeat domain 2 JBrowse link NW_004955507 3,678,009 3,686,967 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004955467 9,241,391 9,256,716 RGD:9068941
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link NW_004955432 3,246,090 3,257,774 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11825
    signaling 4134
      signal transduction 3654
        intracellular signal transduction 1964
          regulation of intracellular signal transduction 1435
            regulation of signal transduction by p53 class mediator 68
              negative regulation of signal transduction by p53 class mediator + 33
              positive regulation of signal transduction by p53 class mediator + 21
              regulation of DNA damage response, signal transduction by p53 class mediator + 33
              regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 31
Path 2
Term Annotations click to browse term
  biological_process 11825
    biological regulation 8660
      regulation of biological process 8225
        regulation of cellular process 7809
          signal transduction 3654
            regulation of signal transduction 2500
              regulation of intracellular signal transduction 1435
                regulation of signal transduction by p53 class mediator 68
                  negative regulation of signal transduction by p53 class mediator + 33
                  positive regulation of signal transduction by p53 class mediator + 21
                  regulation of DNA damage response, signal transduction by p53 class mediator + 33
                  regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 31
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.