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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of signal transduction by p53 class mediator
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Accession:GO:1901796 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.


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regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BOP1 BOP1 ribosomal biogenesis factor JBrowse link 13 37,698,635 37,723,803 RGD:9068941
G HIPK4 homeodomain interacting protein kinase 4 JBrowse link 1 113,297,079 113,304,399 RGD:13508589
G NOP2 NOP2 nucleolar protein JBrowse link 27 38,441,259 38,453,946 RGD:13508589
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 1 108,307,039 108,315,732 RGD:9068941
G PAK1IP1 PAK1 interacting protein 1 JBrowse link 35 10,436,179 10,446,078 RGD:13508589
G PRMT6 protein arginine methyltransferase 6 JBrowse link 6 44,475,829 44,478,215 RGD:13508589
G RPF2 ribosome production factor 2 homolog JBrowse link 12 67,516,991 67,566,287 RGD:9068941
G RPL11 ribosomal protein L11 JBrowse link 2 75,781,210 75,785,614 RGD:9068941
G RPL5 ribosomal protein L5 JBrowse link 6 56,207,171 56,216,030 RGD:9068941
G RRS1 ribosome biogenesis regulator 1 homolog JBrowse link 29 16,016,134 16,018,046 RGD:13508589
G TRIM24 tripartite motif containing 24 JBrowse link 16 10,033,993 10,133,450 RGD:13508589
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD44 CD44 molecule JBrowse link 18 32,735,493 32,826,483 RGD:9068941
G CD74 CD74 molecule JBrowse link 4 58,689,745 58,698,421 RGD:13508589
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link 31 32,564,970 32,655,232 RGD:13508589
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 7 5,816,839 5,826,194 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 2 76,313,742 76,375,716 RGD:9068941
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 36 5,481,449 5,533,139 RGD:13508589
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 81,625,288 81,632,175 RGD:13508589
G PTTG1IP PTTG1 interacting protein JBrowse link 31 38,494,608 38,513,997 RGD:9068941
G SENP2 SUMO specific peptidase 2 JBrowse link 34 18,325,373 18,357,152 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G SNAI1 snail family transcriptional repressor 1 JBrowse link 24 36,498,343 36,503,623 RGD:13508589
G SNAI2 snail family transcriptional repressor 2 JBrowse link 29 1,154,132 1,156,653 RGD:13508589
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCBP4 poly(rC) binding protein 4 JBrowse link 20 37,748,854 37,759,072 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMC10 armadillo repeat containing 10 JBrowse link 18 16,994,583 17,020,417 RGD:9068941
G CEP63 centrosomal protein 63 JBrowse link 23 31,249,517 31,303,145 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G MDM4 MDM4 regulator of p53 JBrowse link 38 1,055,978 1,122,348 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
G PTTG1IP PTTG1 interacting protein JBrowse link 31 38,494,608 38,513,997 RGD:9068941
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 13 3,774,725 3,838,576 RGD:13508589
G RRN3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 6 28,478,770 28,507,722 RGD:13508589
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 6 61,439,414 61,471,414 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:13508589
G BCL2L12 BCL2 like 12 JBrowse link 1 106,865,346 106,873,329 RGD:9068941
G CD44 CD44 molecule JBrowse link 18 32,735,493 32,826,483 RGD:9068941
G CD74 CD74 molecule JBrowse link 4 58,689,745 58,698,421 RGD:13508589
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 30 10,514,633 10,517,963 RGD:13508589
G KDM1A lysine demethylase 1A JBrowse link 2 76,313,742 76,375,716 RGD:9068941
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 36 5,481,449 5,533,139 RGD:13508589
G MUC1 mucin 1, cell surface associated JBrowse link 7 42,338,939 42,344,690 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 26 16,349,513 16,352,805 RGD:9068941
G ZNF385A zinc finger protein 385A JBrowse link 27 928,250 948,275 RGD:13508589
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BDKRB2 bradykinin receptor B2 JBrowse link 8 64,974,588 65,005,682 RGD:13508589
negative regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 30 10,514,633 10,517,963 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 1 108,307,039 108,315,732 RGD:13508589
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 9 38,271,419 38,346,103 RGD:9068941
G RNF34 ring finger protein 34 JBrowse link 26 7,746,460 7,767,967 RGD:13508589
G SENP2 SUMO specific peptidase 2 JBrowse link 34 18,325,373 18,357,152 RGD:9068941
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANKRD1 ankyrin repeat domain 1 JBrowse link 28 5,569,120 5,578,393 RGD:9068941
G ATM ATM serine/threonine kinase JBrowse link 5 24,180,129 24,297,207 RGD:13508589
G ATR ATR serine/threonine kinase JBrowse link 23 38,131,956 38,223,888 RGD:13508589
G DDX5 DEAD-box helicase 5 JBrowse link 9 12,300,706 12,307,931 RGD:13508589
G EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 JBrowse link 35 8,012,304 8,035,176 RGD:13508589
G HIC1 HIC ZBTB transcriptional repressor 1 JBrowse link 9 46,156,909 46,162,849 RGD:9068941
G PLA2R1 phospholipase A2 receptor 1 JBrowse link 36 5,696,733 5,793,599 RGD:13508589
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 1 16,469,793 16,472,910 RGD:13508589
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 1 114,619,478 114,626,082 RGD:13508589
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 30 5,594,327 5,716,082 RGD:13508589
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 10 64,764,275 64,815,937 RGD:13508589
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 1 114,604,265 114,614,764 RGD:13508589
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RPL26 ribosomal protein L26 JBrowse link 5 33,152,114 33,158,237 RGD:9068941
G ZNF385A zinc finger protein 385A JBrowse link 27 928,250 948,275 RGD:13508589
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MSX1 msh homeobox 1 JBrowse link 3 70,232,790 70,236,295 RGD:13508589
G RPL11 ribosomal protein L11 JBrowse link 2 75,781,210 75,785,614 RGD:9068941
G RPS7 ribosomal protein S7 JBrowse link 17 2,139,011 2,143,160 RGD:9068941
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 6 61,439,414 61,471,414 RGD:9068941
G UBB ubiquitin B JBrowse link 5 39,533,365 39,535,120 RGD:9068941
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RPL26 ribosomal protein L26 JBrowse link 5 33,152,114 33,158,237 RGD:9068941
G STEAP3 STEAP3 metalloreductase JBrowse link 19 30,745,910 30,795,310 RGD:9068941
G TP73 tumor protein p73 JBrowse link 5 58,194,385 58,241,159 RGD:9068941
positive regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 JBrowse link 9 24,276,660 24,286,273 RGD:13508589
G CHD5 chromodomain helicase DNA binding protein 5 JBrowse link 5 60,022,451 60,080,663 RGD:9068941
G HEXIM1 HEXIM P-TEFb complex subunit 1 JBrowse link 9 18,384,811 18,387,981 RGD:9068941
G HEXIM1 HEXIM P-TEFb complex subunit 1 RGD:13508589
G RPL11 ribosomal protein L11 JBrowse link 2 75,781,210 75,785,614 RGD:9068941
G RPL23 ribosomal protein L23 JBrowse link 9 23,397,143 23,403,060 RGD:9068941
regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NPM1 nucleophosmin 1 JBrowse link 4 40,756,464 40,770,174 RGD:9068941
G SMYD2 SET and MYND domain containing 2 JBrowse link 7 12,281,581 12,331,294 RGD:13508589
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:13508589
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 15 2,669,546 2,708,480 RGD:13508589
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANKRD2 ankyrin repeat domain 2 JBrowse link 28 10,838,677 10,848,406 RGD:13508589
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:13508589
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HNRNPK heterogeneous nuclear ribonucleoprotein K JBrowse link 1 75,499,334 75,511,525 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16041
    signaling 5936
      signal transduction 5380
        intracellular signal transduction 2457
          regulation of intracellular signal transduction 1614
            regulation of signal transduction by p53 class mediator 70
              negative regulation of signal transduction by p53 class mediator + 31
              positive regulation of signal transduction by p53 class mediator + 26
              regulation of DNA damage response, signal transduction by p53 class mediator + 32
              regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 31
Path 2
Term Annotations click to browse term
  biological_process 16041
    biological regulation 11410
      regulation of biological process 10829
        regulation of cellular process 10367
          signal transduction 5380
            regulation of signal transduction 2794
              regulation of intracellular signal transduction 1614
                regulation of signal transduction by p53 class mediator 70
                  negative regulation of signal transduction by p53 class mediator + 31
                  positive regulation of signal transduction by p53 class mediator + 26
                  regulation of DNA damage response, signal transduction by p53 class mediator + 32
                  regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 31
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.