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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of signal transduction by p53 class mediator
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Accession:GO:1901798 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.
Synonyms:exact_synonym: up-regulation of signal transduction by p53 class mediator;   upregulation of signal transduction by p53 class mediator
 narrow_synonym: activation of signal transduction by p53 class mediator


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positive regulation of signal transduction by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 ISO (PMID:16173922) UniProtKB PMID:16173922 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (PMID:16173922) UniProtKB PMID:16173922 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CHD5 chromodomain helicase DNA binding protein 5 ISO (MGI:MGI:3711389|PMID:17289567) UniProtKB PMID:17289567 MGI:MGI:3711389 NCBI chr 1:4,867,636...4,947,401
Ensembl chr 1:6,125,525...6,191,991
JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 ISO (PMID:22948151) CACAO PMID:22948151 NCBI chr17:12,175,544...12,180,077
Ensembl chr17:12,353,590...12,354,669
JBrowse link
G RPL11 ribosomal protein L11 ISO (MGI:MGI:5897550|PMID:21804542) UniProtKB PMID:21804542 MGI:MGI:5897550 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313
JBrowse link
G RPL23 ribosomal protein L23 ISO (PMID:15314173) CAFA PMID:15314173 NCBI chr17:18,417,964...18,421,708
Ensembl chr17:18,690,682...18,698,253
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD1 ankyrin repeat domain 1 ISO (PMID:20599664) BHF-UCL PMID:20599664 NCBI chr10:87,652,254...87,661,173
Ensembl chr10:91,180,034...91,188,165
JBrowse link
G ATM ATM serine/threonine kinase ISO (PMID:9733515) BHF-UCL PMID:9733515 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G ATR ATR serine/threonine kinase ISO (PMID:9925639) BHF-UCL PMID:9925639 NCBI chr 3:139,482,606...139,612,274
Ensembl chr 3:147,075,185...147,196,261
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (PMID:9529249) BHF-UCL PMID:9529249 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G DDX5 DEAD-box helicase 5 ISO (PMID:15660129) UniProtKB PMID:15660129 NCBI chr17:58,594,956...58,603,570
Ensembl chr17:63,689,082...63,696,142
JBrowse link
G EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 ISO (MGI:MGI:3573962|PMID:15680327) MGI PMID:15680327 MGI:MGI:3573962 NCBI chr 6:7,911,807...7,940,918
Ensembl chr 6:8,192,997...8,222,056
JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 ISO (MGI:MGI:5297787|PMID:16269335) UniProtKB PMID:16269335 MGI:MGI:5297787 NCBI chr17:2,045,960...2,051,483 JBrowse link
G PLA2R1 phospholipase A2 receptor 1 ISO (PMID:19197340) UniProtKB PMID:19197340 NCBI chr2B:47,226,791...47,355,831
Ensembl chr2B:164,605,440...164,726,017
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 ISO (MGI:MGI:2679929|PMID:14500851)
(PMID:15102863)
UniProtKB PMID:14500851, PMID:15102863 MGI:MGI:2679929 NCBI chr18:53,286,590...53,290,913 JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 ISO (MGI:MGI:5318016|PMID:20736167) BHF-UCL PMID:20736167 MGI:MGI:5318016 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 ISO (MGI:MGI:5318016|PMID:20736167) BHF-UCL PMID:20736167 MGI:MGI:5318016 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PYHIN1 pyrin and HIN domain family member 1 ISO (PMID:16479015) UniProtKB PMID:16479015 NCBI chr 1:134,283,998...134,329,531
Ensembl chr 1:138,081,611...138,127,115
JBrowse link
G RPL26 ribosomal protein L26 ISO (PMID:16213212) CAFA PMID:16213212 NCBI chr17:43,274,839...43,282,606
Ensembl chr17:48,009,198...48,015,977
JBrowse link
G ZNF385A zinc finger protein 385A ISO (PMID:17719541) UniProtKB PMID:17719541 NCBI chr12:34,353,975...34,376,172
Ensembl chr12:35,080,820...35,102,248
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSX1 msh homeobox 1 ISO (PMID:15705871) BHF-UCL PMID:15705871 Ensembl chr 4:4,935,600...4,939,079 JBrowse link
G RPL11 ribosomal protein L11 ISO (MGI:MGI:5883206|PMID:22262176) CAFA PMID:22262176 MGI:MGI:5883206 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313
JBrowse link
G RPS7 ribosomal protein S7 ISO (PMID:17310983) CAFA PMID:17310983 NCBI chr2A:3,593,350...3,599,106 JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 ISO (MGI:MGI:5553386|PMID:24523556) UniProtKB PMID:24523556 MGI:MGI:5553386 NCBI chr 1:119,224,304...119,267,986
Ensembl chr 1:88,077,420...88,121,056
JBrowse link
G UBB ubiquitin B ISO (PMID:17571083) MGI PMID:17571083 NCBI chr17:35,286,699...35,288,429 JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL26 ribosomal protein L26 ISO (PMID:16213212)
(MGI:MGI:5882892|PMID:16213212)
CAFA PMID:16213212 MGI:MGI:5882892 NCBI chr17:43,274,839...43,282,606
Ensembl chr17:48,009,198...48,015,977
JBrowse link
G STEAP3 STEAP3 metalloreductase ISO (MGI:MGI:4367682|PMID:18617898) MGI PMID:18617898 MGI:MGI:4367682 NCBI chr2B:6,166,296...6,208,338
Ensembl chr2B:119,752,363...119,787,051
JBrowse link
G TP73 tumor protein p73 ISO (MGI:MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:MGI:3584078 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    positive regulation of biological process 5633
      positive regulation of signaling 1729
        positive regulation of signal transduction 1493
          positive regulation of intracellular signal transduction 955
            positive regulation of signal transduction by p53 class mediator 25
              positive regulation of DNA damage response, signal transduction by p53 class mediator + 14
              positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 8
Path 2
Term Annotations click to browse term
  biological_process 12524
    biological regulation 9129
      regulation of biological process 8652
        regulation of cellular process 8181
          signal transduction 3809
            intracellular signal transduction 2043
              signal transduction by p53 class mediator 142
                regulation of signal transduction by p53 class mediator 72
                  positive regulation of signal transduction by p53 class mediator 25
                    positive regulation of DNA damage response, signal transduction by p53 class mediator + 14
                    positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.