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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cell cycle checkpoint
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Accession:GO:1901976 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cell cycle checkpoint.
Comment:Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
Synonyms:related_synonym: regulation of G1/S checkpoint;   regulation of G1/S transition checkpoint
 alt_id: GO:2001047


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdt1 chromatin licensing and DNA replication factor 1 JBrowse link 19 55,381,565 55,386,511 RGD:1624291
negative regulation of DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brd4 bromodomain containing 4 JBrowse link 7 14,222,101 14,303,055 RGD:1624291
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:10401658
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Ddx39b DExD-box helicase 39B JBrowse link 20 4,806,103 4,818,600 RGD:1624291
RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
G Thoc5 THO complex 5 JBrowse link 14 85,138,219 85,171,729 RGD:1624291
RGD:1600115
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 JBrowse link 20 3,329,677 3,344,286 RGD:1600115
RGD:1624291
positive regulation of cell cycle checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
positive regulation of DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccar2 cell cycle and apoptosis regulator 2 JBrowse link 15 51,818,887 51,834,443 RGD:1624291
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:1600115
RGD:1624291
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1624291
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:1624291
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
G Pcid2 PCI domain containing 2 JBrowse link 16 81,757,582 81,783,047 RGD:1624291
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1600115
RGD:1624291
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
regulation of DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cry1 cryptochrome circadian regulator 1 JBrowse link 7 24,534,593 24,634,098 RGD:1624291
RGD:1600115
G Cul4a cullin 4A JBrowse link 16 81,718,784 81,756,653 RGD:1624291
G Etaa1 ETAA1 activator of ATR kinase JBrowse link 14 102,290,655 102,293,674 RGD:1624291
RGD:13792537
G Fbxo4 F-box protein 4 JBrowse link 2 53,797,954 53,811,134 RGD:1624291
G Fem1b fem-1 homolog B JBrowse link 8 67,695,041 67,708,313 RGD:1624291
RGD:1600115
G Nek1 NIMA-related kinase 1 JBrowse link 16 32,321,010 32,439,421 RGD:1624291
G Rfwd3 ring finger and WD repeat domain 3 JBrowse link 19 42,960,597 42,971,894 RGD:1624291
G Rnaseh2b ribonuclease H2, subunit B JBrowse link 15 45,422,010 45,472,792 RGD:1624291
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:1624291
RGD:1600115
G Wdr76 WD repeat domain 76 JBrowse link 3 113,445,498 113,479,483 RGD:13792537
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anapc15 anaphase promoting complex subunit 15 JBrowse link 1 166,981,738 166,985,363 RGD:1624291
RGD:13792537
RGD:1600115
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1624291
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
G Lcmt1 leucine carboxyl methyltransferase 1 JBrowse link 1 193,335,629 193,391,620 RGD:1624291
RGD:1600115
G Usp44 ubiquitin specific peptidase 44 JBrowse link 7 34,714,293 34,759,352 RGD:1624291
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rint1 RAD50 interactor 1 JBrowse link 4 7,851,602 7,885,446 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cell cycle checkpoint 188
        regulation of cell cycle checkpoint 34
          negative regulation of cell cycle checkpoint + 8
          positive regulation of cell cycle checkpoint + 9
          regulation of DNA damage checkpoint + 19
          regulation of spindle checkpoint + 14
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          negative regulation of cellular process 5079
            negative regulation of cell cycle 461
              cell cycle checkpoint 188
                regulation of cell cycle checkpoint 34
                  negative regulation of cell cycle checkpoint + 8
                  positive regulation of cell cycle checkpoint + 9
                  regulation of DNA damage checkpoint + 19
                  regulation of spindle checkpoint + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.