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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell cycle checkpoint
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Accession:GO:1901977 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.
Comment:Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
Synonyms:exact_synonym: down regulation of cell cycle checkpoint;   downregulation of cell cycle checkpoint
 narrow_synonym: inhibition of cell cycle checkpoint
 related_synonym: negative regulation of G1/S checkpoint;   negative regulation of G1/S transition checkpoint
 alt_id: GO:2001048


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 ISO (PMID:23728299) RGD PMID:23728299 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:20637979 RGD:10401658 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Da2-19 uncharacterized LOC302729 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:48,196,789...48,213,506
Ensembl chr  X:48,196,916...48,213,505
JBrowse link
G Ddx39b DExD-box helicase 39B ISO
ISS
(PMID:22144908)
GO_REF:0000024
RGD
UniProt
PMID:22144908 GO_REF:0000024 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568
JBrowse link
G Thoc1 THO complex 1 ISO (PMID:22144908) RGD PMID:22144908 NCBI chr18:1,142,540...1,177,084
Ensembl chr18:1,142,782...1,176,974
JBrowse link
G Thoc5 THO complex 5 ISO
ISS
(PMID:22144908)
GO_REF:0000024
RGD
UniProt
PMID:22144908 GO_REF:0000024 NCBI chr14:85,138,219...85,171,729
Ensembl chr14:85,142,279...85,171,726
JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 IEA
ISO
GO_REF:0000107
UniProtKB:Q15554 (PMID:23426265)
Ensembl
RGD
PMID:23426265 GO_REF:0000107 NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      negative regulation of cellular process 5144
        negative regulation of cell cycle checkpoint 8
          negative regulation of DNA damage checkpoint + 7
          negative regulation of spindle checkpoint + 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of cellular process 12560
          regulation of cell cycle 1018
            negative regulation of cell cycle 444
              cell cycle checkpoint 166
                regulation of cell cycle checkpoint 34
                  negative regulation of cell cycle checkpoint 8
                    negative regulation of DNA damage checkpoint + 7
                    negative regulation of spindle checkpoint + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.