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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of hematopoietic stem cell differentiation
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Accession:GO:1902036 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
Synonyms:exact_synonym: regulation of haematopoietic stem cell differentiation;   regulation of haemopoietic stem cell differentiation;   regulation of hemopoietic stem cell differentiation


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regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,713,881 130,887,675 RGD:2290271
G M Ap2a2 adaptor-related protein complex 2, alpha 2 subunit JBrowse link 7 141,562,180 141,633,011 RGD:2290270
G H CBFB core-binding factor subunit beta JBrowse link 16 67,029,149 67,101,058 RGD:2290271
G M Cdk6 cyclin dependent kinase 6 RGD:9068941
G V CDK6 cyclin dependent kinase 6 JBrowse link 21 56,167,731 56,403,976 RGD:9068941
G P CDK6 cyclin dependent kinase 6 JBrowse link 9 72,510,858 72,765,631 RGD:14298760
G S Cdk6 cyclin dependent kinase 6 JBrowse link NW_004936803 1,025,047 1,229,396 RGD:9068941
G D CDK6 cyclin dependent kinase 6 JBrowse link 14 18,178,352 18,413,869 RGD:13508589
G B CDK6 cyclin dependent kinase 6 JBrowse link 7 84,603,419 84,835,082 RGD:9068941
G C Cdk6 cyclin dependent kinase 6 JBrowse link NW_004955432 9,521,794 9,727,772 RGD:9068941
G R Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:1624291
G M Cdk6 cyclin-dependent kinase 6 JBrowse link 5 3,341,004 3,531,008 RGD:2290270
G H CDK6 cyclin dependent kinase 6 JBrowse link 7 92,604,921 92,836,573 RGD:2290271
G M Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 RGD:9068941
G V EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 14 70,246,081 70,290,851 RGD:9068941
G P EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 3 103,041,029 103,096,741 RGD:14298760
G S Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link NW_004936663 1,127,047 1,157,263 RGD:9068941
G D EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 17 29,494,641 29,537,933 RGD:13508589
G B EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 2A 37,130,386 37,184,587 RGD:9068941
G C Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link NW_004955441 4,908,318 4,944,343 RGD:9068941
G R Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 JBrowse link 6 1,428,845 1,466,193 RGD:1624291
RGD:1600115
G M Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 JBrowse link 17 78,850,504 78,882,572 RGD:2290270
G H EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 2 37,099,210 37,157,065 RGD:2290271
G H GATA1 GATA binding protein 1 JBrowse link X 48,786,540 48,794,311 RGD:2290271
G H GATA2 GATA binding protein 2 JBrowse link 3 128,479,422 128,493,201 RGD:2290271
G H GATA3 GATA binding protein 3 JBrowse link 10 8,045,420 8,075,198 RGD:2290271
G H ITCH itchy E3 ubiquitin protein ligase JBrowse link 20 34,363,273 34,511,773 RGD:2290271
G H KMT2A lysine methyltransferase 2A JBrowse link 11 118,436,492 118,526,832 RGD:2290271
G H LDB1 LIM domain binding 1 JBrowse link 10 102,102,100 102,120,368 RGD:2290271
G H LMO1 LIM domain only 1 JBrowse link 11 8,224,304 8,268,787 RGD:2290271
G H LMO2 LIM domain only 2 JBrowse link 11 33,858,576 33,892,076 RGD:2290271
G H METTL3 methyltransferase like 3 JBrowse link 14 21,498,138 21,511,340 RGD:2290271
G H MYB MYB proto-oncogene, transcription factor JBrowse link 6 135,181,308 135,219,172 RGD:2290271
G H OSM oncostatin M JBrowse link 22 30,262,829 30,266,851 RGD:2290271
G M Prkdc protein kinase, DNA-activated, catalytic subunit RGD:9068941
G V PRKDC protein kinase, DNA-activated, catalytic subunit JBrowse link 8 43,915,226 44,119,547 RGD:9068941
G P PRKDC protein kinase, DNA-activated, catalytic subunit JBrowse link 4 79,687,375 79,850,146 RGD:9068941
G S Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link NW_004936590 4,722,914 4,887,615 RGD:9068941
G D PRKDC protein kinase, DNA-activated, catalytic subunit JBrowse link 29 24,904 243,926 RGD:13508589
G B PRKDC protein kinase, DNA-activated, catalytic subunit JBrowse link 8 44,201,391 44,386,803 RGD:9068941
G C Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link NW_004955454 7,733,697 7,890,896 RGD:9068941
G R Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G M Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 16 15,637,444 15,842,239 RGD:2290270
G H PRKDC protein kinase, DNA-activated, catalytic subunit JBrowse link 8 47,773,111 47,960,136 RGD:2290271
G H PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:2290271
G H PSMA2 proteasome 20S subunit alpha 2 JBrowse link 7 42,916,861 42,932,174 RGD:2290271
G H PSMA3 proteasome 20S subunit alpha 3 JBrowse link 14 58,244,805 58,272,009 RGD:2290271
G H PSMA4 proteasome 20S subunit alpha 4 JBrowse link 15 78,540,405 78,552,417 RGD:2290271
G H PSMA5 proteasome 20S subunit alpha 5 JBrowse link 1 109,399,042 109,426,448 RGD:2290271
G H PSMA6 proteasome 20S subunit alpha 6 JBrowse link 14 35,278,558 35,317,493 RGD:2290271
G H PSMA7 proteasome 20S subunit alpha 7 JBrowse link 20 62,136,733 62,143,394 RGD:2290271
G H PSMA8 proteasome 20S subunit alpha 8 JBrowse link 18 26,133,869 26,193,355 RGD:2290271
G H PSMB1 proteasome 20S subunit beta 1 JBrowse link 6 170,535,120 170,553,307 RGD:2290271
G H PSMB10 proteasome 20S subunit beta 10 JBrowse link 16 67,934,506 67,936,850 RGD:2290271
G H PSMB11 proteasome subunit beta 11 JBrowse link 14 23,042,212 23,044,060 RGD:2290271
G H PSMB2 proteasome 20S subunit beta 2 JBrowse link 1 35,599,541 35,641,526 RGD:2290271
G H PSMB3 proteasome 20S subunit beta 3 JBrowse link 17 38,752,741 38,764,225 RGD:2290271
G H PSMB4 proteasome 20S subunit beta 4 JBrowse link 1 151,399,573 151,401,937 RGD:2290271
G H PSMB5 proteasome 20S subunit beta 5 JBrowse link 14 23,025,851 23,035,220 RGD:2290271
G H PSMB6 proteasome 20S subunit beta 6 JBrowse link 17 4,796,144 4,798,503 RGD:2290271
G H PSMB7 proteasome 20S subunit beta 7 JBrowse link 9 124,353,465 124,415,442 RGD:2290271
G H PSMB8 proteasome 20S subunit beta 8 JBrowse link 6 32,840,717 32,844,679 RGD:2290271
G H PSMB9 proteasome 20S subunit beta 9 JBrowse link 6 32,854,192 32,859,851 RGD:2290271
G H PSMC1 proteasome 26S subunit, ATPase 1 JBrowse link 14 90,256,553 90,275,429 RGD:2290271
G H PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 7 103,344,405 103,369,395 RGD:2290271
G H PSMC3 proteasome 26S subunit, ATPase 3 JBrowse link 11 47,418,769 47,426,473 RGD:2290271
G H PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 19 39,971,005 39,981,764 RGD:2290271
G H PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 63,827,431 63,832,027 RGD:2290271
G H PSMC6 proteasome 26S subunit, ATPase 6 JBrowse link 14 52,707,163 52,728,590 RGD:2290271
G H PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 2 231,056,864 231,172,827 RGD:2290271
G H PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 108,084,205 108,091,644 RGD:2290271
G H PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 17 32,444,510 32,483,319 RGD:2290271
G H PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 17 67,337,916 67,366,598 RGD:2290271
G H PSMD13 proteasome 26S subunit, non-ATPase 13 JBrowse link 11 236,972 252,984 RGD:2290271
G H PSMD14 proteasome 26S subunit, non-ATPase 14 JBrowse link 2 161,308,425 161,411,717 RGD:2290271
G H PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 3 184,299,241 184,309,050 RGD:2290271
G H PSMD3 proteasome 26S subunit, non-ATPase 3 JBrowse link 17 39,980,807 39,997,959 RGD:2290271
G H PSMD4 proteasome 26S subunit, non-ATPase 4 JBrowse link 1 151,254,734 151,267,479 RGD:2290271
G H PSMD5 proteasome 26S subunit, non-ATPase 5 JBrowse link 9 120,816,053 120,842,922 RGD:2290271
G H PSMD6 proteasome 26S subunit, non-ATPase 6 JBrowse link 3 64,010,549 64,024,010 RGD:2290271
G H PSMD7 proteasome 26S subunit, non-ATPase 7 JBrowse link 16 74,296,814 74,306,288 RGD:2290271
G H PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 19 38,374,550 38,383,824 RGD:2290271
G H PSMD9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 121,888,790 121,918,297 RGD:2290271
G H PSME1 proteasome activator subunit 1 JBrowse link 14 24,136,158 24,138,967 RGD:2290271
G H PSME2 proteasome activator subunit 2 JBrowse link 14 24,143,365 24,146,646 RGD:2290271
G H PSME3 proteasome activator subunit 3 JBrowse link 17 42,833,397 42,843,760 RGD:2290271
G H PSME4 proteasome activator subunit 4 JBrowse link 2 53,864,069 53,970,993 RGD:2290271
G H PSMF1 proteasome inhibitor subunit 1 JBrowse link 20 1,113,229 1,172,246 RGD:2290271
G M Pus7 pseudouridine synthase 7 RGD:9068941
G V PUS7 pseudouridine synthase 7 JBrowse link 21 74,381,482 74,447,531 RGD:9068941
G P PUS7 pseudouridine synthase 7 JBrowse link 9 105,325,762 105,388,972 RGD:14298760
G S Pus7 pseudouridine synthase 7 JBrowse link NW_004936479 18,354,009 18,395,765 RGD:9068941
G D PUS7 pseudouridine synthase 7 JBrowse link 18 14,882,276 14,939,070 RGD:13508589
G B PUS7 pseudouridine synthase 7 JBrowse link 7 97,447,332 97,512,812 RGD:9068941
G C Pus7 pseudouridine synthase 7 JBrowse link NW_004955410 10,062,768 10,119,751 RGD:9068941
G R Pus7 pseudouridine synthase 7 JBrowse link 4 7,889,727 7,931,357 RGD:1624291
G M Pus7 pseudouridylate synthase 7 JBrowse link 5 23,740,165 23,783,711 RGD:2290270
G H PUS7 pseudouridine synthase 7 JBrowse link 7 105,456,501 105,522,271 RGD:2290271
G H RUNX1 RUNX family transcription factor 1 JBrowse link 21 34,787,801 35,049,334 RGD:2290271
G H SEM1 SEM1 26S proteasome complex subunit JBrowse link 7 96,481,626 96,709,891 RGD:2290271
G M Setd1a SET domain containing 1A, histone lysine methyltransferase RGD:9068941
G V SETD1A SET domain containing 1A, histone lysine methyltransferase JBrowse link 5 27,645,908 27,675,500 RGD:9068941
G P SETD1A SET domain containing 1A, histone lysine methyltransferase JBrowse link 3 17,463,768 17,490,397 RGD:14298760
G S Setd1a SET domain containing 1A, histone lysine methyltransferase JBrowse link NW_004936501 13,339,426 13,363,551 RGD:9068941
G D SETD1A SET domain containing 1A, histone lysine methyltransferase JBrowse link 6 17,224,107 17,246,527 RGD:13508589
G B SETD1A SET domain containing 1A, histone lysine methyltransferase JBrowse link 16 23,984,260 24,019,579 RGD:9068941
G C Setd1a SET domain containing 1A, histone lysine methyltransferase JBrowse link NW_004955493 7,808,652 7,834,886 RGD:9068941
G R Setd1a SET domain containing 1A, histone lysine methyltransferase JBrowse link 1 199,222,584 199,247,993 RGD:1624291
G M Setd1a SET domain containing 1A JBrowse link 7 127,777,389 127,800,122 RGD:2290270
G H SETD1A SET domain containing 1A, histone lysine methyltransferase JBrowse link 16 30,956,618 30,984,664 RGD:2290271
G H TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor JBrowse link 1 47,216,290 47,232,389 RGD:2290271
G H TCF12 transcription factor 12 JBrowse link 15 56,918,090 57,292,595 RGD:2290271
G H TCF3 transcription factor 3 JBrowse link 19 1,609,292 1,652,615 RGD:2290271
G H TP73 tumor protein p73 JBrowse link 1 3,652,516 3,736,201 RGD:2290271
G H YAP1 Yes1 associated transcriptional regulator JBrowse link 11 102,109,957 102,233,424 RGD:2290271
G M Ythdf2 YTH N6-methyladenosine RNA binding protein 2 RGD:9068941
G V YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 20 104,041,657 104,078,705 RGD:9068941
G P YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 6 85,717,147 85,756,750 RGD:14298760
G S Ythdf2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link NW_004936474 12,791,121 12,827,122 RGD:9068941
G D YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 2 71,760,232 71,791,420 RGD:13508589
G B YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 1 28,007,592 28,041,179 RGD:9068941
G C Ythdf2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link NW_004955452 7,783,398 7,815,468 RGD:9068941
G R Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
G M Ythdf2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 4 132,184,916 132,212,256 RGD:2290270
G H YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 1 28,736,621 28,769,775 RGD:2290271
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G M Hspa9 heat shock protein family A (Hsp70) member 9 RGD:9068941
G V HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 23 41,230,675 41,251,177 RGD:9068941
G P HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 2 140,515,239 140,532,164 RGD:14298760
G S Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link NW_004936531 7,702,186 7,716,428 RGD:9068941
G D HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 11 26,122,917 26,142,458 RGD:13508589
G B HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 5 133,934,859 133,955,048 RGD:9068941
G C Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link NW_004955418 1,915,985 1,931,017 RGD:9068941
G R Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:1600115
RGD:1624291
G M Hspa9 heat shock protein 9 JBrowse link 18 34,937,414 34,954,351 RGD:2290270
G H HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 5 138,553,756 138,575,401 RGD:2290271
G M N4bp2l2 NEDD4 binding protein 2 like 2 RGD:9068941
G V N4BP2L2 NEDD4 binding protein 2 like 2 JBrowse link 3 11,191,215 11,287,434 RGD:9068941
G P N4BP2L2 NEDD4 binding protein 2 like 2 JBrowse link 11 8,891,053 8,997,810 RGD:9068941
G S N4bp2l2 NEDD4 binding protein 2 like 2 JBrowse link NW_004936472 27,045,052 27,134,170 RGD:9068941
G D N4BP2L2 NEDD4 binding protein 2 like 2 JBrowse link 25 7,622,032 7,694,396 RGD:9068941
G B N4BP2L2 NEDD4 binding protein 2 like 2 JBrowse link 13 13,691,326 13,803,162 RGD:9068941
G C N4bp2l2 NEDD4 binding protein 2 like 2 JBrowse link NW_004955431 13,314,075 13,418,090 RGD:9068941
G R N4bp2l2 NEDD4 binding protein 2-like 2 JBrowse link 12 627,128 650,604 RGD:1624291
G M N4bp2l2 NEDD4 binding protein 2-like 2 JBrowse link 5 150,599,931 150,665,748 RGD:2290270
G H N4BP2L2 NEDD4 binding protein 2 like 2 JBrowse link 13 32,432,417 32,542,710 RGD:2290271
G M Nfe2l2 nuclear factor, erythroid 2 like 2 RGD:9068941
G V NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 10 62,789,647 62,825,651 RGD:9068941
G P NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 15 82,967,485 83,146,185 RGD:9068941
G S Nfe2l2 nuclear factor, erythroid 2 like 2 JBrowse link NW_004936509 6,589,967 6,621,171 RGD:9068941
G D NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 36 20,989,205 21,087,044 RGD:13508589
G B NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2B 64,509,446 64,544,600 RGD:9068941
G C Nfe2l2 nuclear factor, erythroid 2 like 2 JBrowse link NW_004955403 19,510,122 19,536,428 RGD:9068941
G R Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
G M Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:2290270
G H NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:2290271
positive regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G M Foxc1 forkhead box C1 RGD:9068941
G V FOXC1 forkhead box C1 JBrowse link 17 70,533,048 70,536,555 RGD:9068941
G P FOXC1 forkhead box C1 JBrowse link 7 837,088 840,593 RGD:14298760
G B FOXC1 forkhead box C1 JBrowse link 6 1,429,051 1,433,180 RGD:9068941
G R Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G M Foxc1 forkhead box C1 JBrowse link 13 31,806,646 31,810,635 RGD:2290270
G H FOXC1 forkhead box C1 JBrowse link 6 1,609,915 1,613,897 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 130409
    developmental process 50443
      regulation of developmental process 21978
        regulation of cell differentiation 15647
          regulation of hematopoietic progenitor cell differentiation 280
            regulation of hematopoietic stem cell differentiation 142
              negative regulation of hematopoietic stem cell differentiation 24
              positive regulation of hematopoietic stem cell differentiation 5
Path 2
Term Annotations click to browse term
  biological_process 130409
    developmental process 50443
      anatomical structure development 46757
        multicellular organism development 42799
          system development 39750
            immune system development 8139
              hematopoietic or lymphoid organ development 7649
                hemopoiesis 7264
                  hematopoietic progenitor cell differentiation 1230
                    regulation of hematopoietic progenitor cell differentiation 280
                      regulation of hematopoietic stem cell differentiation 142
                        negative regulation of hematopoietic stem cell differentiation 24
                        positive regulation of hematopoietic stem cell differentiation 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.