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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
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Accession:GO:1902042 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
Synonyms:exact_synonym: down regulation of extrinsic apoptotic signaling pathway via death domain receptors;   downregulation of extrinsic apoptotic signaling pathway via death domain receptors
 narrow_synonym: down regulation of death receptor-mediated apoptosis;   downregulation of death receptor-mediated apoptosis;   inhibition of death receptor-mediated apoptosis;   inhibition of extrinsic apoptotic signaling pathway via death domain receptors;   negative regulation of death receptor-mediated apoptosis


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negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 ISO (PMID:22711822) BHF-UCL PMID:22711822 NCBI chr 4:94,026,391...94,082,206
Ensembl chr 4:94,026,385...94,080,422
JBrowse link
G BCL2L1 BCL2 like 1 IEA Ensembl GO_REF:0000107 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,141...35,415,359
JBrowse link
G BRCA1 BRCA1 DNA repair associated IEA Ensembl GO_REF:0000107 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,855,570
JBrowse link
G CAPS calcyphosine ISO (MGI:2450205|PMID:12466268) MGI PMID:12466268 MGI:2450205 NCBI chr 2:73,122,784...73,124,979
Ensembl chr 2:73,123,191...73,130,030
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,615...104,844,921
JBrowse link
G DAPK1 death associated protein kinase 1 ISO (MGI:2152512|PMID:11485996) MGI PMID:11485996 MGI:2152512 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,644...27,954,350
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,044,769
JBrowse link
G FAIM Fas apoptotic inhibitory molecule IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:79,397,647...79,411,917
Ensembl chr13:79,397,319...79,411,913
JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:15,779,329...15,813,029
Ensembl chr 5:15,779,334...15,812,547
JBrowse link
G FGA fibrinogen alpha chain IEA Ensembl GO_REF:0000107 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202
JBrowse link
G FGB fibrinogen beta chain IEA Ensembl GO_REF:0000107 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,594,255...74,607,360
JBrowse link
G FGG fibrinogen gamma chain IEA Ensembl GO_REF:0000107 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,686,118
JBrowse link
G GPX1 glutathione peroxidase 1 IEA Ensembl GO_REF:0000107 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
G GSK3B glycogen synthase kinase 3 beta IEA Ensembl GO_REF:0000107 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,574
JBrowse link
G HGF hepatocyte growth factor IEA Ensembl GO_REF:0000107 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,437,087...98,513,156
JBrowse link
G HMGB2 high mobility group box 2 ISS AgBase GO_REF:0000024 NCBI chr14:16,709,966...16,712,288
Ensembl chr14:16,710,047...16,717,126
JBrowse link
G HMOX1 heme oxygenase 1 ISS
IEA
AgBase
Ensembl
GO_REF:0000024 GO_REF:0000107
G ICAM1 intercellular adhesion molecule 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein IEA Ensembl GO_REF:0000107 NCBI chr14:115,243,035...115,278,137
Ensembl chr14:115,252,517...115,277,672
JBrowse link
G PEA15 proliferation and apoptosis adaptor protein 15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:90,263,600...90,276,142
Ensembl chr 4:90,263,584...90,274,144
JBrowse link
G PSEN2 presenilin 2 ISO (MGI:1099227|PMID:9353287) MGI PMID:9353287 MGI:1099227 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,550...14,561,858
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase IEA Ensembl GO_REF:0000107 NCBI chr13:68,581,128...68,657,911
Ensembl chr13:68,580,812...68,657,829
JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:40,075,259...40,151,034 JBrowse link
G RNF34 ring finger protein 34 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:31,202,030...31,229,529
Ensembl chr14:31,200,373...31,229,484
JBrowse link
G SERPINE1 serpin family E member 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,133...75,345,926
JBrowse link
G TMBIM1 transmembrane BAX inhibitor motif containing 1 ISO (PMID:21107705) UniProtKB PMID:21107705 NCBI chr15:120,348,740...120,365,055
Ensembl chr15:120,348,735...120,365,007
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822
JBrowse link
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase IEA Ensembl GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,520
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16552
    cellular process 15783
      signal transduction 5927
        cell surface receptor signaling pathway 2487
          extrinsic apoptotic signaling pathway 230
            extrinsic apoptotic signaling pathway via death domain receptors 77
              negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 29
                negative regulation of TRAIL-activated apoptotic signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 16552
    biological regulation 12014
      regulation of biological process 11424
        regulation of cellular process 10975
          regulation of cell death 1701
            regulation of programmed cell death 1531
              regulation of apoptotic process 1497
                regulation of apoptotic signaling pathway 398
                  regulation of extrinsic apoptotic signaling pathway 167
                    regulation of extrinsic apoptotic signaling pathway via death domain receptors 49
                      negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 29
                        negative regulation of TRAIL-activated apoptotic signaling pathway 1
paths to the root