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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of hypoxia-inducible factor-1alpha signaling pathway
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Accession:GO:1902073 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
Synonyms:exact_synonym: activation of HIF1alpha pathway;   activation of hypoxia-inducible factor-1alpha signalling pathway;   positive regulation of HIF1alpha pathway;   positive regulation of hypoxia-inducible factor-1alpha signalling pathway;   up regulation of HIF1alpha pathway;   up regulation of hypoxia-inducible factor-1alpha signaling pathway;   up regulation of hypoxia-inducible factor-1alpha signalling pathway;   upregulation of HIF1alpha pathway;   upregulation of hypoxia-inducible factor-1alpha signaling pathway;   upregulation of hypoxia-inducible factor-1alpha signalling pathway
 narrow_synonym: activation of hypoxia-inducible factor-1alpha signaling pathway;   hypoxic stabilization of HIF1A


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positive regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RWDD3 RWD domain containing 3 IEA Ensembl
InterPro
GO_REF:0000002, GO_REF:0000107 NCBI chr 4:122,187,949...122,203,146
Ensembl chr 4:122,187,949...122,203,115
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    cellular process 15756
      signal transduction 5920
        positive regulation of signal transduction 1591
          positive regulation of hypoxia-inducible factor-1alpha signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8965
      response to abiotic stimulus 1463
        response to oxygen levels 518
          response to decreased oxygen levels 453
            response to hypoxia 422
              cellular response to hypoxia 175
                regulation of cellular response to hypoxia 17
                  positive regulation of cellular response to hypoxia 2
                    positive regulation of hypoxia-inducible factor-1alpha signaling pathway 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.