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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of metaphase/anaphase transition of cell cycle
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Accession:GO:1902100 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
Synonyms:exact_synonym: down regulation of metaphase/anaphase transition of cell cycle;   downregulation of metaphase/anaphase transition of cell cycle
 narrow_synonym: inhibition of metaphase/anaphase transition of cell cycle


show annotations for term's descendants           Sort by:
 
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
meiotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase ISO
IBA
MGI:MGI:5056148 (MGI:MGI:5049806|PMID:21558374)
PMID:21873635
RGD PMID:21558374, PMID:21873635 MGI:MGI:5049806, RGD:13792537 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO
IEA
(PMID:17227893)
GO_REF:0000107
RGD
Ensembl
PMID:17227893 GO_REF:0000107 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Atm ATM serine/threonine kinase ISO (PMID:11943150) RGD PMID:11943150 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Aurkb aurora kinase B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISS
ISO
GO_REF:0000024
(PMID:12805209)
UniProt
RGD
PMID:12805209 GO_REF:0000024 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G Cenpe centromere protein E ISO (MGI:MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:MGI:2673075 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Ik IK cytokine ISO
ISS
(PMID:22351768)
GO_REF:0000024
RGD
UniProt
PMID:22351768 GO_REF:0000024 NCBI chr18:29,587,901...29,602,705
Ensembl chr18:29,587,901...29,608,338
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member ISO MGI:MGI:3844604 (MGI:MGI:3844372|PMID:19376971) RGD PMID:19376971 MGI:MGI:3844372 NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592
JBrowse link
G Klhl22 kelch-like family member 22 ISO
IBA
ISS
(PMID:23455478)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23455478, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:87,646,489...87,718,808
Ensembl chr11:87,677,966...87,718,826
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 ISO
IBA
(PMID:18981471)
PMID:21873635
RGD PMID:18981471, PMID:21873635 RGD:13792537 NCBI chr12:16,410,083...16,721,232
Ensembl chr12:16,410,083...16,719,824
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO
IBA
MGI:MGI:2178781 (MGI:MGI:1930685|PMID:11201745)
PMID:21873635
(PMID:18981471)
RGD PMID:11201745, PMID:18981471, PMID:21873635 MGI:MGI:1930685, RGD:13792537 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Plk1 polo-like kinase 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:23455478)
Ensembl
UniProt
RGD
PMID:23455478 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Psmg2 proteasome assembly chaperone 2 ISO (MGI:MGI:2388532|PMID:12147697) RGD PMID:12147697 MGI:MGI:2388532 NCBI chr18:63,394,991...63,420,491
Ensembl chr18:63,394,900...63,409,600
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:19,628,070...19,652,914
Ensembl chr10:19,628,258...19,652,898
JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(MGI:MGI:5318128|PMID:22405274)
Ensembl
UniProt
RGD
PMID:22405274, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5318128, RGD:13792537 NCBI chr10:74,724,070...74,849,172
Ensembl chr10:74,724,549...74,849,194
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISS
ISO
GO_REF:0000024
(PMID:20133940)
UniProt
RGD
PMID:20133940 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 ISO
ISS
(PMID:28553959)
GO_REF:0000024
RGD
UniProt
PMID:28553959 GO_REF:0000024 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919
JBrowse link
G Ttk Ttk protein kinase ISO
IBA
MGI:MGI:5056148 (MGI:MGI:5608719|PMID:25197064)
PMID:21873635
RGD PMID:25197064, PMID:21873635 MGI:MGI:5608719, RGD:13792537 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Zfp207 zinc finger protein 207 ISO
IBA
(PMID:24462186), (PMID:24462187)
PMID:21873635
RGD PMID:24462186, PMID:24462187, PMID:21873635 RGD:13792537 NCBI chr10:67,762,970...67,784,854
Ensembl chr10:67,762,995...67,774,787
JBrowse link
G Zw10 zw10 kinetochore protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:53,365,881...53,390,742
Ensembl chr 8:53,365,857...53,390,930
JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mos MOS proto-oncogene, serine/threonine kinase ISS
ISO
IEA
IBA
GO_REF:0000024
(MGI:MGI:67285|PMID:8015610), (MGI:MGI:67286|PMID:8015609)
GO_REF:0000107
(PMID:12533425)
PMID:21873635
UniProt
RGD
Ensembl
PMID:8015609, PMID:8015610, PMID:12533425, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:67285, MGI:MGI:67286, RGD:13792537 NCBI chr 5:16,746,085...16,747,392
Ensembl chr 5:16,746,197...16,747,222
JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 ISO (PMID:11988738), (PMID:16921029) RGD PMID:11988738, PMID:16921029 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Rad21 RAD21 cohesin complex component ISO (MGI:MGI:1340883|PMID:10375619) RGD PMID:10375619 MGI:MGI:1340883 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673
JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19229290)
Ensembl
UniProt
RGD
PMID:19229290 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO (PMID:20870947)
(MGI:MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:MGI:4839685 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Ndc80 NDC80 kinetochore complex component ISO (PMID:25743205) RGD PMID:25743205 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Pcid2 PCI domain containing 2 ISO (PMID:20870947)
(MGI:MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:MGI:4839685 NCBI chr16:81,757,582...81,783,047
Ensembl chr16:81,756,971...81,783,047
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISS
ISO
GO_REF:0000024
(PMID:18981471), (PMID:19273613)
UniProt
RGD
PMID:18981471, PMID:19273613 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 ISO
IBA
ISS
(PMID:21926987)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:21926987, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:166,981,738...166,985,363
Ensembl chr 1:166,983,175...166,985,054
JBrowse link
G Ccnb1 cyclin B1 ISO (PMID:18195732) RGD PMID:18195732 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 ISS
ISO
IEA
GO_REF:0000024
(PMID:19282672)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19282672 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 ISO
IEA
(PMID:17724024)
GO_REF:0000107
RGD
Ensembl
PMID:17724024 GO_REF:0000107 NCBI chr 1:193,335,629...193,391,620
Ensembl chr 1:193,335,645...193,391,638
JBrowse link
G Usp44 ubiquitin specific peptidase 44 ISO (MGI:MGI:5448515|PMID:21853124) RGD PMID:21853124 MGI:MGI:5448515 NCBI chr 7:34,714,293...34,759,352
Ensembl chr 7:34,744,483...34,759,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell cycle process 1210
        cell cycle phase transition 431
          metaphase/anaphase transition of cell cycle 57
            negative regulation of metaphase/anaphase transition of cell cycle 37
              negative regulation of metaphase/anaphase transition of meiotic cell cycle + 2
              negative regulation of mitotic metaphase/anaphase transition + 36
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          organelle organization 4101
            chromosome organization 1251
              sister chromatid segregation 186
                regulation of sister chromatid segregation 62
                  metaphase/anaphase transition of cell cycle 57
                    regulation of metaphase/anaphase transition of cell cycle 54
                      negative regulation of metaphase/anaphase transition of cell cycle 37
                        negative regulation of metaphase/anaphase transition of meiotic cell cycle + 2
                        negative regulation of mitotic metaphase/anaphase transition + 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.