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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
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Accession:GO:1902165 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
Synonyms:related_synonym: regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis


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regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO (MGI:MGI:4881379|PMID:20673990) MGI PMID:20673990 MGI:MGI:4881379 NCBI chrNW_004955432:3,246,090...3,257,774 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 ISO (MGI:MGI:3584078|PMID:15983387) UniProtKB PMID:15983387 MGI:MGI:3584078 NCBI chrNW_004955481:6,986,128...7,031,113 JBrowse link
G Bcl2l12 BCL2 like 12 ISO (MGI:MGI:4834958|PMID:20837658) MGI PMID:20837658 MGI:MGI:4834958 NCBI chrNW_004955559:1,217,797...1,224,875 JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO (MGI:MGI:3690285|PMID:17045821)
(PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Cd74 CD74 molecule ISO (MGI:MGI:3690285|PMID:17045821)
(PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chrNW_004955415:4,129,151...4,138,336 JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO (MGI:MGI:5438719|PMID:22768269) MGI PMID:22768269 MGI:MGI:5438719 NCBI chrNW_004955416:10,223,213...10,226,978 JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:17805299) BHF-UCL PMID:17805299 NCBI chrNW_004955452:3,044,042...3,104,650 JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chrNW_004955449:13,834,561...13,875,864 JBrowse link
G Mif macrophage migration inhibitory factor ISO (PMID:17045821) BHF-UCL PMID:17045821 NCBI chrNW_004955455:8,367,566...8,368,460 JBrowse link
G Muc1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:2152474|PMID:11672522) BHF-UCL PMID:11672522 MGI:MGI:2152474 NCBI chrNW_004955425:20,280,725...20,307,663 JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 ISO (PMID:15735003) BHF-UCL PMID:15735003 NCBI chrNW_004955455:11,195,399...11,198,402 JBrowse link
G Znf385a zinc finger protein 385A ISO (PMID:17719541) UniProtKB PMID:17719541 NCBI chrNW_004955458:1,610,245...1,631,639 JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 ISO (PMID:16213212)
(MGI:MGI:5882892|PMID:16213212)
CAFA PMID:16213212 MGI:MGI:5882892 NCBI chrNW_004955467:8,519,760...8,525,514 JBrowse link
G Steap3 STEAP3 metalloreductase ISO (MGI:MGI:4367682|PMID:18617898) MGI PMID:18617898 MGI:MGI:4367682 NCBI chrNW_004955459:10,441,906...10,485,235 JBrowse link
G Tp73 tumor protein p73 ISO (MGI:MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:MGI:3584078 NCBI chrNW_004955486:7,914,608...7,961,992 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    cellular process 11058
      regulation of cellular process 7832
        regulation of cellular response to stress 668
          regulation of response to DNA damage stimulus 208
            regulation of intrinsic apoptotic signaling pathway in response to DNA damage 38
              regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16
                negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3
Path 2
Term Annotations click to browse term
  biological_process 11857
    biological regulation 8688
      regulation of biological process 8250
        regulation of cellular process 7832
          regulation of cell death 1564
            regulation of programmed cell death 1411
              regulation of apoptotic process 1385
                regulation of apoptotic signaling pathway 403
                  regulation of intrinsic apoptotic signaling pathway 168
                    regulation of intrinsic apoptotic signaling pathway by p53 class mediator 31
                      regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16
                        negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                        positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.