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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
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Accession:GO:1902166 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
Synonyms:exact_synonym: down regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
 narrow_synonym: inhibition of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
 related_synonym: down regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;   downregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;   inhibition of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;   negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis


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negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 ISO (MGI:MGI:3584078|PMID:15983387) UniProtKB PMID:15983387 MGI:MGI:3584078 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G BCL2L12 BCL2 like 12 ISO (MGI:MGI:4834958|PMID:20837658) MGI PMID:20837658 MGI:MGI:4834958 NCBI chr19:46,679,749...46,688,539 JBrowse link
G CD44 CD44 molecule (Indian blood group) ISO (PMID:17045821)
(MGI:MGI:3690285|PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009
JBrowse link
G CD74 CD74 molecule ISO (PMID:17045821)
(MGI:MGI:3690285|PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334
JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 ISO (MGI:MGI:5438719|PMID:22768269) MGI PMID:22768269 MGI:MGI:5438719 NCBI chr15:22,732,742...22,737,522
Ensembl chr15:40,821,759...40,827,070
JBrowse link
G KDM1A lysine demethylase 1A ISO (PMID:17805299) BHF-UCL PMID:17805299 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692
JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chr2B:47,004,211...47,059,901
Ensembl chr2B:164,377,605...164,432,907
JBrowse link
G MIF macrophage migration inhibitory factor ISO (PMID:17045821) BHF-UCL PMID:17045821 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G SIRT1 sirtuin 1 ISO (MGI:MGI:2152474|PMID:11672522) BHF-UCL PMID:11672522 MGI:MGI:2152474 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 ISO (PMID:15735003) BHF-UCL PMID:15735003 NCBI chr12:118,025,599...118,028,045
Ensembl chr12:121,400,063...121,402,506
JBrowse link
G ZNF385A zinc finger protein 385A ISO (PMID:17719541) UniProtKB PMID:17719541 NCBI chr12:34,353,975...34,376,172
Ensembl chr12:35,080,820...35,102,248
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    cellular process 11625
      negative regulation of cellular process 4413
        negative regulation of response to DNA damage stimulus 77
          negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 27
            negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
Path 2
Term Annotations click to browse term
  biological_process 12529
    biological regulation 9138
      regulation of biological process 8652
        regulation of cellular process 8181
          regulation of cell death 1641
            regulation of programmed cell death 1484
              regulation of apoptotic process 1457
                regulation of apoptotic signaling pathway 417
                  regulation of intrinsic apoptotic signaling pathway 173
                    regulation of intrinsic apoptotic signaling pathway in response to DNA damage 39
                      regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16
                        negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.