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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
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Accession:GO:1902254 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
Synonyms:exact_synonym: down regulation of intrinsic apoptotic signaling pathway by p53 class mediator;   down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator;   negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 narrow_synonym: inhibition of intrinsic apoptotic signaling pathway by p53 class mediator;   inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 related_synonym: down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis;   downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis;   inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis;   negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis


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negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc10 armadillo repeat containing 10 JBrowse link 4 10,004,846 10,020,017 RGD:1624291
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1624291
G Mdm4 MDM4 regulator of p53 JBrowse link 13 49,786,776 49,828,780 RGD:1624291
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
G Pttg1ip PTTG1 interacting protein JBrowse link 20 11,746,369 11,764,097 RGD:1624291
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 7 76,750,045 76,780,817 RGD:1624291
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 10 3,170,387 3,214,648 RGD:1624291
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 JBrowse link 2 250,709,812 250,744,216 RGD:1624291
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Bcl2l12 BCL2 like 12 JBrowse link 1 100,984,550 100,993,269 RGD:1624291
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
RGD:1600115
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:13792537
RGD:1600115
G Ell3 elongation factor for RNA polymerase II 3 JBrowse link 3 113,400,395 113,405,869 RGD:1624291
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Marchf7 membrane associated ring-CH-type finger 7 JBrowse link 3 46,284,961 46,325,230 RGD:1624291
RGD:1600115
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Triap1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 12 46,987,404 46,989,906 RGD:1624291
G Zfp385a zinc finger protein 385A JBrowse link 7 144,939,616 144,966,364 RGD:1624291
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      signal transduction 6968
        intracellular signal transduction 2597
          signal transduction by p53 class mediator 140
            intrinsic apoptotic signaling pathway by p53 class mediator 79
              negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 22
                negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          regulation of cell death 1790
            regulation of programmed cell death 1617
              regulation of apoptotic process 1590
                regulation of apoptotic signaling pathway 430
                  regulation of intrinsic apoptotic signaling pathway 176
                    regulation of intrinsic apoptotic signaling pathway by p53 class mediator 32
                      negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 22
                        negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                        negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.