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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
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Accession:GO:1902254 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
Synonyms:exact_synonym: down regulation of intrinsic apoptotic signaling pathway by p53 class mediator;   down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator;   negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 narrow_synonym: inhibition of intrinsic apoptotic signaling pathway by p53 class mediator;   inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 related_synonym: down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis;   downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis;   inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis;   negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis


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negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:21,646,006...21,662,699
Ensembl chr 5:21,645,813...21,662,694
JBrowse link
G Cep63 centrosomal protein 63 IGI (MGI:MGI:5662131|PMID:26158450) MGI PMID:26158450 MGI:MGI:5662131 NCBI chr 9:102,586,578...102,626,564
Ensembl chr 9:102,584,588...102,626,534
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Mdm4 transformed mouse 3T3 cell double minute 4 IMP (MGI:MGI:2182884|PMID:12101245) UniProt PMID:12101245 MGI:MGI:2182884 NCBI chr 1:132,986,105...133,030,587
Ensembl chr 1:132,959,484...133,030,561
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr17:10,840,359...12,063,370
Ensembl chr17:10,840,384...12,063,361
JBrowse link
G Pttg1ip pituitary tumor-transforming 1 interacting protein ISO MGI GO_REF:0000008, MGI:MGI:2154458 NCBI chr10:77,581,655...77,598,732
Ensembl chr10:77,581,720...77,598,732
JBrowse link
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) IMP (MGI:MGI:2670318|PMID:12858174) MGI PMID:12858174 MGI:MGI:2670318 NCBI chr15:37,923,952...37,961,119
Ensembl chr15:37,923,952...37,961,318
JBrowse link
G Rrn3 RRN3 RNA polymerase I transcription factor homolog (yeast) IMP (MGI:MGI:3583493|PMID:15989966) MGI PMID:15989966 MGI:MGI:3583493 NCBI chr16:13,780,699...13,814,841
Ensembl chr16:13,780,708...13,814,839
JBrowse link
G Sh3glb1 SH3-domain GRB2-like B1 (endophilin) IMP (MGI:MGI:5553386|PMID:24523556) UniProtKB PMID:24523556 MGI:MGI:5553386 NCBI chr 3:144,683,665...144,720,408
Ensembl chr 3:144,683,678...144,720,335
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 IMP (MGI:MGI:3584078|PMID:15983387) UniProtKB PMID:15983387 MGI:MGI:3584078 NCBI chr11:80,089,379...80,135,797
Ensembl chr11:80,089,400...80,135,794
JBrowse link
G Bcl2l12 BCL2-like 12 (proline rich) IDA (MGI:MGI:4834958|PMID:20837658) MGI PMID:20837658 MGI:MGI:4834958 NCBI chr 7:44,991,222...44,997,638
Ensembl chr 7:44,991,222...44,998,712
JBrowse link
G Cd44 CD44 antigen IMP
ISO
(MGI:MGI:3690285|PMID:17045821) BHF-UCL
MGI
PMID:17045821 GO_REF:0000096, MGI:MGI:3690285, MGI:MGI:4834177 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) IMP
IBA
ISO
(MGI:MGI:3690285|PMID:17045821)
(MGI:MGI:6201960|PMID:21873635)
BHF-UCL
GO_Central
MGI
PMID:17045821, PMID:21873635 GO_REF:0000096, MGI:MGI:3690285, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr18:60,803,849...60,812,652
Ensembl chr18:60,803,848...60,812,652
JBrowse link
G Ell3 elongation factor RNA polymerase II-like 3 IMP (MGI:MGI:5438719|PMID:22768269) MGI PMID:22768269 MGI:MGI:5438719 NCBI chr 2:121,439,027...121,442,601
Ensembl chr 2:121,439,010...121,444,278
JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:136,550,533...136,602,787
Ensembl chr 4:136,550,540...136,602,723
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 2:60,209,936...60,248,385
Ensembl chr 2:60,209,887...60,250,676
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:75,859,353...75,860,277
Ensembl chr10:75,859,353...75,860,240
JBrowse link
G Muc1 mucin 1, transmembrane ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 3:89,229,056...89,233,381
Ensembl chr 3:89,229,057...89,233,381
JBrowse link
G Sirt1 sirtuin 1 IMP (MGI:MGI:2152474|PMID:11672522) BHF-UCL PMID:11672522 MGI:MGI:2152474 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:115,341,231...115,343,553
Ensembl chr 5:115,341,225...115,343,569
JBrowse link
G Zfp385a zinc finger protein 385A ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:103,313,895...103,340,086
Ensembl chr15:103,313,895...103,340,093
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor, beta 2 IGI (MGI:MGI:3654719|PMID:16571598) MGI PMID:16571598 MGI:MGI:3654719 NCBI chr12:105,563,172...105,595,244
Ensembl chr12:105,563,226...105,595,237
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23366
    cellular process 17362
      signal transduction 6321
        intracellular signal transduction 2562
          signal transduction by p53 class mediator 142
            intrinsic apoptotic signaling pathway by p53 class mediator 80
              negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 22
                negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
Path 2
Term Annotations click to browse term
  biological_process 23366
    biological regulation 13064
      regulation of biological process 12440
        regulation of cellular process 11888
          regulation of cell death 1774
            regulation of programmed cell death 1605
              regulation of apoptotic process 1578
                regulation of apoptotic signaling pathway 430
                  regulation of intrinsic apoptotic signaling pathway 178
                    regulation of intrinsic apoptotic signaling pathway by p53 class mediator 32
                      negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 22
                        negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                        negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.