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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
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Accession:GO:1902254 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
Synonyms:exact_synonym: down regulation of intrinsic apoptotic signaling pathway by p53 class mediator;   down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway by p53 class mediator;   downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator;   negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 narrow_synonym: inhibition of intrinsic apoptotic signaling pathway by p53 class mediator;   inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 related_synonym: down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis;   downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis;   inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis;   negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis


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negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 ISO (PMID:17904127) RGD PMID:17904127 NCBI chr 4:10,004,846...10,020,017
Ensembl chr 4:10,004,848...10,020,022
JBrowse link
G Cep63 centrosomal protein 63 ISO MGI:MGI:98834 (MGI:MGI:5662131|PMID:26158450) RGD PMID:26158450 MGI:MGI:5662131 NCBI chr 8:111,063,988...111,116,014
Ensembl chr 8:111,064,049...111,116,014
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mdm4 MDM4 regulator of p53 ISO (MGI:MGI:2182884|PMID:12101245) RGD PMID:12101245 MGI:MGI:2182884 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:23985028) RGD PMID:23985028 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Pttg1ip PTTG1 interacting protein ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,746,369...11,764,097
Ensembl chr20:11,746,370...11,764,233
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B ISO MGI:MGI:2672883 (MGI:MGI:2670318|PMID:12858174) RGD PMID:12858174 MGI:MGI:2670318 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor ISO MGI:MGI:3584037 (MGI:MGI:3583493|PMID:15989966) RGD PMID:15989966 MGI:MGI:3583493 NCBI chr10:3,170,387...3,214,648
Ensembl chr10:3,170,742...3,214,655
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 ISO (MGI:MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:MGI:5553386 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 ISO (MGI:MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:MGI:3584078 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Bcl2l12 BCL2 like 12 ISO (MGI:MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:MGI:4834958 NCBI chr 1:100,984,550...100,993,269
Ensembl chr 1:100,984,550...100,993,269
JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO
IEA
(PMID:17045821)
GO_REF:0000107
(MGI:MGI:3690285|PMID:17045821)
RGD
Ensembl
PMID:17045821 GO_REF:0000107, MGI:MGI:3690285 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd74 CD74 molecule ISO
IBA
ISS
(MGI:MGI:3690285|PMID:17045821)
PMID:21873635
GO_REF:0000024
(PMID:17045821)
RGD
BHF-UCL
PMID:17045821, PMID:21873635 GO_REF:0000024, MGI:MGI:3690285, RGD:13792537 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO (MGI:MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:MGI:5438719 NCBI chr 3:113,400,395...113,405,869
Ensembl chr 3:113,401,734...113,405,829
JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO
ISS
(PMID:29295817)
GO_REF:0000024
RGD
UniProt
PMID:29295817 GO_REF:0000024 NCBI chr 3:46,284,961...46,325,230
Ensembl chr 3:46,286,712...46,324,057
JBrowse link
G Mif macrophage migration inhibitory factor ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Muc1 mucin 1, cell surface associated ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:2152474|PMID:11672522) RGD PMID:11672522 MGI:MGI:2152474 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
G Zfp385a zinc finger protein 385A ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:144,939,616...144,966,364
Ensembl chr 7:144,939,619...144,966,370
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 ISO
IEA
MGI:MGI:98834|MGI:MGI:99702 (MGI:MGI:3654719|PMID:16571598)
GO_REF:0000107
RGD
Ensembl
PMID:16571598 GO_REF:0000107, MGI:MGI:3654719 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      signal transduction 7015
        intracellular signal transduction 2615
          signal transduction by p53 class mediator 140
            intrinsic apoptotic signaling pathway by p53 class mediator 79
              negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 22
                negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of cellular process 12570
          regulation of cell death 1800
            regulation of programmed cell death 1626
              regulation of apoptotic process 1599
                regulation of apoptotic signaling pathway 432
                  regulation of intrinsic apoptotic signaling pathway 179
                    regulation of intrinsic apoptotic signaling pathway by p53 class mediator 32
                      negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 22
                        negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 12
                        negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.