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ONTOLOGY REPORT - ANNOTATIONS


Term:deactivation of mitotic spindle assembly checkpoint
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Accession:GO:1902426 term browser browse the term
Definition:A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
Comment:A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known.
Synonyms:exact_synonym: down regulation of mitotic cell cycle spindle assembly checkpoint;   down regulation of mitotic spindle assembly checkpoint;   downregulation of mitotic cell cycle spindle assembly checkpoint;   downregulation of mitotic spindle assembly checkpoint;   mitotic spindle assembly checkpoint silencing;   mitotic spindle assembly deactivation;   negative regulation of mitotic cell cycle spindle assembly checkpoint
 broad_synonym: negative regulation of mitotic spindle assembly checkpoint
 related_synonym: down regulation of Mad2-dependent checkpoint;   downregulation of Mad2-dependent checkpoint;   inhibition of Mad2-dependent checkpoint;   inhibition of mitotic cell cycle spindle assembly checkpoint;   inhibition of mitotic spindle assembly checkpoint;   negative regulation of Mad2-dependent checkpoint


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 ISO (PMID:22581055) CAFA PMID:22581055 NCBI chr 5:64,566,035...64,570,361
Ensembl chr 5:64,566,043...64,570,748
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    cellular process 15442
      cell cycle process 1164
        negative regulation of cell cycle process 226
          deactivation of mitotic spindle assembly checkpoint 1
Path 2
Term Annotations click to browse term
  biological_process 16162
    cellular process 15442
      cellular component organization or biogenesis 6021
        cellular component organization 5852
          organelle organization 3698
            organelle fission 478
              nuclear division 423
                mitotic nuclear division 276
                  mitotic sister chromatid segregation 159
                    regulation of mitotic sister chromatid segregation 68
                      regulation of mitotic sister chromatid separation 57
                        metaphase/anaphase transition of mitotic cell cycle 56
                          regulation of mitotic metaphase/anaphase transition 53
                            negative regulation of mitotic metaphase/anaphase transition 37
                              mitotic spindle assembly checkpoint 35
                                regulation of mitotic cell cycle spindle assembly checkpoint 13
                                  deactivation of mitotic spindle assembly checkpoint 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.