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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of apoptotic DNA fragmentation
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Accession:GO:1902510 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.
Comment:DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).
Synonyms:exact_synonym: regulation of DNA catabolic process during apoptosis;   regulation of DNA catabolism during apoptosis;   regulation of DNA fragmentation involved in apoptotic nuclear change;   regulation of endonucleolytic DNA catabolic process involved in apoptosis
 broad_synonym: regulation of DNA fragmentation;   regulation of chromatinolysis


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regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:1624291
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cidea cell death-inducing DFFA-like effector a JBrowse link 18 63,082,861 63,108,450 RGD:1624291
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:1624291
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 JBrowse link 5 166,409,460 166,430,291 RGD:13781945
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:13462066
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:9685355
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10403035
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:10402776
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    regulation of biological process 12959
      regulation of cellular process 12442
        regulation of cellular component organization 2611
          regulation of apoptotic DNA fragmentation 12
            negative regulation of apoptotic DNA fragmentation 3
            positive regulation of apoptotic DNA fragmentation 5
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              DNA metabolic process 911
                DNA catabolic process 35
                  DNA catabolic process, endonucleolytic 27
                    apoptotic DNA fragmentation 19
                      regulation of apoptotic DNA fragmentation 12
                        negative regulation of apoptotic DNA fragmentation 3
                        positive regulation of apoptotic DNA fragmentation 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.