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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intracellular signal transduction
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Accession:GO:1902532 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
Synonyms:exact_synonym: down regulation of intracellular signal transduction;   down regulation of intracellular signaling chain;   downregulation of intracellular signal transduction;   downregulation of intracellular signaling chain;   negative regulation of intracellular protein kinase cascade;   negative regulation of intracellular signaling cascade;   negative regulation of intracellular signaling chain
 narrow_synonym: down regulation of intracellular signal transduction pathway;   downregulation of intracellular signal transduction pathway;   downregulation of intracellular signaling cascade;   downregulation of signal transmission via intracellular cascade;   inhibition of intracellular signal transduction;   inhibition of intracellular signal transduction pathway;   inhibition of intracellular signaling cascade;   inhibition of intracellular signaling chain;   inhibition of signal transmission via intracellular cascade;   negative regulation of intracellular signal transduction pathway;   negative regulation of signal transmission via intracellular cascade
 related_synonym: down regulation of intracellular signaling pathway;   down regulation of signal transduction via intracellular signaling cascade;   down-regulation of intracellular signaling cascade;   down-regulation of signal transmission via intracellular cascade;   downregulation of intracellular signaling pathway;   downregulation of signal transduction via intracellular signaling cascade;   inhibition of intracellular signaling pathway;   inhibition of signal transduction via intracellular signaling cascade;   negative regulation of intracellular signaling pathway;   negative regulation of signal transduction via intracellular signaling cascade
 alt_id: GO:0010741


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negative regulation of intracellular signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDIT4 DNA damage inducible transcript 4 JBrowse link 10 68,796,712 68,798,840 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 52,318,497 52,455,741 RGD:9068941
inactivation of MAPK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 7 108,497,125 108,533,090 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 197,293,039 197,333,828 RGD:9068941
G DUSP16 dual specificity phosphatase 16 JBrowse link 12 12,497,185 12,585,591 RGD:9068941
G DUSP19 dual specificity phosphatase 19 JBrowse link 2B 70,347,712 70,371,852 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 17 13,618,860 13,631,743 RGD:9068941
G DUSP4 dual specificity phosphatase 4 JBrowse link 8 28,623,777 28,641,432 RGD:9068941
G DUSP6 dual specificity phosphatase 6 JBrowse link 12 86,875,289 86,879,731 RGD:9068941
G DUSP8 dual specificity phosphatase 8 JBrowse link 11 1,592,858 1,611,740 RGD:9068941
G DUSP9 dual specificity phosphatase 9 JBrowse link X 143,192,599 143,201,647 RGD:9068941
G LAX1 lymphocyte transmembrane adaptor 1 JBrowse link 1 179,370,097 179,379,618 RGD:9068941
G PRKCA protein kinase C alpha JBrowse link 17 60,246,485 60,747,158 RGD:9068941
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 15 17,182,976 17,286,566 RGD:9068941
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 2A 65,380,608 65,503,139 RGD:9068941
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 19 35,482,436 35,490,745 RGD:9068941
inactivation of MAPKK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EPHB2 EPH receptor B2 JBrowse link 1 21,895,961 22,107,649 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 77,332,926 77,648,474 RGD:9068941
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARRDC3 arrestin domain containing 3 JBrowse link 5 23,991,325 24,005,913 RGD:9068941
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 1 179,231,712 179,348,759 RGD:9068941
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,154,731 50,187,948 RGD:9068941
G PDE4B phosphodiesterase 4B JBrowse link 1 65,038,120 65,620,764 RGD:9068941
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLP1 amyloid beta precursor like protein 1 JBrowse link 19 32,786,362 32,797,728 RGD:9068941
G GRK2 G protein-coupled receptor kinase 2 JBrowse link 11 62,624,647 62,644,846 RGD:9068941
G GRK5 G protein-coupled receptor kinase 5 JBrowse link 10 115,776,236 116,026,221 RGD:9068941
G MRAP melanocortin 2 receptor accessory protein JBrowse link 21 18,665,550 18,679,537 RGD:9068941
G MRAP2 melanocortin 2 receptor accessory protein 2 JBrowse link 6 81,914,767 82,041,579 RGD:9068941
G OPRL1 opioid related nociceptin receptor 1 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 6 151,827,323 151,937,658 RGD:9068941
G PTGER3 prostaglandin E receptor 3 JBrowse link 1 70,076,610 70,271,475 RGD:9068941
G SSTR4 somatostatin receptor 4 JBrowse link 20 22,982,009 22,986,058 RGD:9068941
negative regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GIT1 GIT ArfGAP 1 JBrowse link 17 27,185,025 27,201,146 RGD:9068941
negative regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTN3 actinin alpha 3 JBrowse link 11 61,905,722 61,922,227 RGD:9068941
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 1 179,231,712 179,348,759 RGD:9068941
G CHP1 calcineurin like EF-hand protein 1 JBrowse link 15 20,172,874 20,223,382 RGD:9068941
G CMYA5 cardiomyopathy associated 5 JBrowse link 5 35,515,463 35,620,430 RGD:9068941
G DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 JBrowse link 12 21,241,325 21,260,321 RGD:9068941
G FHL2 four and a half LIM domains 2 JBrowse link 2A 96,391,513 96,469,267 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 116,943,205 117,215,001 RGD:9068941
G HOMER2 homer scaffold protein 2 JBrowse link 15 62,617,905 62,762,903 RGD:9068941
G HOMER3 homer scaffold protein 3 JBrowse link 19 18,367,191 18,379,454 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 17 31,729,429 31,736,216 RGD:9068941
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 9,871,700 10,028,704 RGD:9068941
G MYOZ1 myozenin 1 JBrowse link 10 70,179,020 70,194,885 RGD:9068941
G MYOZ2 myozenin 2 JBrowse link 4 111,330,427 111,382,323 RGD:9068941
G PRNP prion protein JBrowse link 20 4,713,616 4,728,847 RGD:9068941
G RCAN1 regulator of calcineurin 1 JBrowse link 21 20,889,123 20,987,964 RGD:9068941
G TBC1D10C TBC1 domain family member 10C JBrowse link 11 62,762,075 62,768,569 RGD:9068941
negative regulation of calcium-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD22 CD22 molecule JBrowse link 19 32,265,278 32,294,122 RGD:9068941
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 JBrowse link 3 4,448,574 4,802,545 RGD:9068941
G SIGLEC11 sialic acid binding Ig like lectin 11 JBrowse link 19 46,961,548 46,974,158 RGD:9068941
G SLA2 Src like adaptor 2 JBrowse link 20 32,945,409 32,978,966 RGD:9068941
negative regulation of CAMKK-AMPK signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGLN1 egl-9 family hypoxia inducible factor 1 JBrowse link 1 206,915,541 206,976,656 RGD:9068941
negative regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLNR apelin receptor JBrowse link 11 52,475,088 52,479,102 RGD:9068941
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme JBrowse link 19 592,856 602,811 RGD:9068941
G CRHR2 corticotropin releasing hormone receptor 2 JBrowse link 7 31,265,619 31,313,902 RGD:9068941
G CRTC3 CREB regulated transcription coactivator 3 JBrowse link 15 69,217,679 69,333,897 RGD:9068941
G LPAR1 lysophosphatidic acid receptor 1 JBrowse link 9 82,013,960 82,179,227 RGD:9068941
G MGRN1 mahogunin ring finger 1 JBrowse link 16 3,550,352 3,615,693 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 4 147,542,551 147,586,397 RGD:9068941
G NUCB2 nucleobindin 2 JBrowse link 11 17,331,742 17,404,682 RGD:9068941
G OPRL1 opioid related nociceptin receptor 1 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 6 151,827,323 151,937,658 RGD:9068941
G PDE10A phosphodiesterase 10A JBrowse link 6 163,274,252 163,612,749 RGD:9068941
G PDE11A phosphodiesterase 11A JBrowse link 2B 64,903,170 65,332,922 RGD:9068941
G PDE2A phosphodiesterase 2A JBrowse link 11 67,653,335 67,753,450 RGD:9068941
G PDE3A phosphodiesterase 3A JBrowse link 12 20,380,213 20,690,540 RGD:9068941
G PDE3B phosphodiesterase 3B JBrowse link 11 14,746,301 14,961,316 RGD:9068941
G PDE4D phosphodiesterase 4D JBrowse link 5 53,510,287 55,039,181 RGD:9068941
G RGS2 regulator of G protein signaling 2 JBrowse link 1 168,273,112 168,276,348 RGD:9068941
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 5 129,775,011 129,794,853 RGD:9068941
negative regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTNR1B melatonin receptor 1B JBrowse link 11 87,996,805 88,009,865 RGD:9068941
G PDE10A phosphodiesterase 10A JBrowse link 6 163,274,252 163,612,749 RGD:9068941
G PDE11A phosphodiesterase 11A JBrowse link 2B 64,903,170 65,332,922 RGD:9068941
G PDE2A phosphodiesterase 2A JBrowse link 11 67,653,335 67,753,450 RGD:9068941
G PDZD3 PDZ domain containing 3 JBrowse link 11 114,024,150 114,028,884 RGD:9068941
G THBS1 thrombospondin 1 JBrowse link 15 18,521,802 18,538,172 RGD:9068941
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD44 CD44 molecule (Indian blood group) JBrowse link 11 35,110,732 35,258,238 RGD:9068941
G CD74 CD74 molecule JBrowse link 5 145,825,635 145,836,916 RGD:9068941
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link 21 23,729,204 23,878,820 RGD:9068941
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 1 182,237,556 182,255,984 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 1 22,205,624 22,269,571 RGD:9068941
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 2B 47,004,211 47,059,901 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 66,322,340 66,357,010 RGD:9068941
G MIF macrophage migration inhibitory factor JBrowse link 22 4,646,986 4,647,831 RGD:9068941
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 97,182,090 97,189,523 RGD:9068941
G PTTG1IP PTTG1 interacting protein JBrowse link 21 31,143,600 31,169,231 RGD:9068941
G SENP2 SUMO specific peptidase 2 JBrowse link 3 182,606,922 182,655,518 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G SNAI1 snail family transcriptional repressor 1 JBrowse link 20 46,321,075 46,328,865 RGD:9068941
G SNAI2 snail family transcriptional repressor 2 JBrowse link 8 45,341,857 45,345,544 RGD:9068941
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 7 19,761,041 19,765,665 RGD:9068941
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCBP4 poly(rC) binding protein 4 JBrowse link 3 51,898,857 51,908,932 RGD:9068941
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2L1 BCL2 like 1 JBrowse link 20 27,955,688 28,015,950 RGD:9068941
G CREB3 cAMP responsive element binding protein 3 JBrowse link 9 35,583,351 35,587,870 RGD:9068941
G CREB3L1 cAMP responsive element binding protein 3 like 1 JBrowse link 11 46,236,384 46,280,145 RGD:9068941
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 16 37,210,170 37,221,961 RGD:9068941
G HSPA1A heat shock protein family A (Hsp70) member 1A JBrowse link 6 31,476,710 31,491,411 RGD:9068941
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 143,988,720 144,010,078 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 12 48,343,621 48,488,337 RGD:9068941
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 3 190,890,242 190,995,133 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 6,722,260 6,745,915 RGD:9068941
G PDX1 pancreatic and duodenal homeobox 1 JBrowse link 13 9,199,572 9,206,202 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 46,854,918 46,929,509 RGD:9068941
G SELENOS selenoprotein S JBrowse link 15 79,995,678 80,002,159 RGD:9068941
G SYVN1 synoviolin 1 JBrowse link 11 60,489,626 60,496,945 RGD:9068941
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 12 38,986,844 39,010,307 RGD:9068941
G TXNDC12 thioredoxin domain containing 12 JBrowse link 1 51,271,206 51,307,248 RGD:9068941
G WFS1 wolframin ER transmembrane glycoprotein RGD:9068941
G XBP1 X-box binding protein 1 JBrowse link 22 9,863,479 9,869,491 RGD:9068941
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HYOU1 hypoxia up-regulated 1 JBrowse link 11 113,882,418 113,895,438 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
negative regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 101,834,189 102,005,811 RGD:9068941
G ACE2 angiotensin I converting enzyme 2 JBrowse link X 8,189,267 8,229,415 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 183,876,051 183,889,723 RGD:9068941
G ANKRD26 ankyrin repeat domain 26 JBrowse link 10 27,111,909 27,210,001 RGD:9068941
G ARRB1 arrestin beta 1 JBrowse link 11 70,319,935 70,411,276 RGD:9068941
G ATF3 activating transcription factor 3 JBrowse link 1 188,176,728 188,188,842 RGD:9068941
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,215,215 26,227,261 RGD:9068941
G C1QL4 complement C1q like 4 JBrowse link 12 39,414,635 39,419,422 RGD:9068941
G C3H3orf33 chromosome 3 C3orf33 homolog JBrowse link 3 152,818,445 152,861,945 RGD:9068941
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 JBrowse link 1 19,437,761 19,441,573 RGD:9068941
G CAV1 caveolin 1 JBrowse link 7 108,497,125 108,533,090 RGD:9068941
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit JBrowse link 11 3,543,450 3,552,036 RGD:9068941
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 15 10,525,535 10,667,227 RGD:9068941
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit JBrowse link 4 34,654,043 34,675,984 RGD:9068941
G CNKSR3 CNKSR family member 3 JBrowse link 6 152,221,458 152,326,885 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 17 27,522,647 27,530,767 RGD:9068941
G CSK C-terminal Src kinase JBrowse link 15 53,724,814 53,745,710 RGD:9068941
G DAB2 DAB adaptor protein 2 JBrowse link 5 70,951,198 71,004,836 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 92,696,798 92,912,425 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 3 194,386,263 194,648,015 RGD:9068941
G DMD dystrophin JBrowse link X 23,728,650 26,338,849 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 5 168,121,536 168,124,671 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 197,293,039 197,333,828 RGD:9068941
G DUSP26 dual specificity phosphatase 26 JBrowse link 8 32,906,182 32,915,015 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 17 13,618,860 13,631,743 RGD:9068941
G DUSP4 dual specificity phosphatase 4 JBrowse link 8 28,623,777 28,641,432 RGD:9068941
G DUSP6 dual specificity phosphatase 6 JBrowse link 12 86,875,289 86,879,731 RGD:9068941
G EIF3A eukaryotic translation initiation factor 3 subunit A JBrowse link 10 115,608,394 115,654,586 RGD:9068941
G EMILIN1 elastin microfibril interfacer 1 JBrowse link 2A 27,077,551 27,085,437 RGD:9068941
G EPHB2 EPH receptor B2 JBrowse link 1 21,895,961 22,107,649 RGD:9068941
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 1 6,771,619 6,786,217 RGD:9068941
G EZR ezrin JBrowse link 6 156,656,146 156,709,986 RGD:9068941
G FBLN1 fibulin 1 JBrowse link 22 26,390,379 26,488,737 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 62,942,756 62,945,701 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 12 99,986,887 100,066,773 RGD:9068941
G ITGB1BP1 integrin subunit beta 1 binding protein 1 JBrowse link 2A 9,396,553 9,413,408 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 9 78,634,545 78,639,447 RGD:9068941
G LIF LIF interleukin 6 family cytokine JBrowse link 22 11,276,576 11,282,972 RGD:9068941
G LMO3 LIM domain only 3 JBrowse link 12 16,544,474 16,605,925 RGD:9068941
G LOC100967334 G-protein coupled estrogen receptor 1 JBrowse link 7 1,245,873 1,251,915 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 52,318,497 52,455,741 RGD:9068941
G NDRG2 NDRG family member 2 JBrowse link 14 1,831,764 1,840,819 RGD:9068941
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 19 50,735,124 50,765,556 RGD:9068941
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 11 274,904 281,590 RGD:9068941
G PHB prohibitin JBrowse link 17 8,189,555 8,200,491 RGD:9068941
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 18 56,084,851 56,338,551 RGD:9068941
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 19 9,389,829 9,404,099 RGD:9068941
G PSCA prostate stem cell antigen JBrowse link 8 139,384,002 139,394,993 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 84,587,841 84,689,043 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 46,854,918 46,929,509 RGD:9068941
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 18 1,440,837 1,538,501 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 174,246,389 174,364,893 RGD:9068941
G PTPRR protein tyrosine phosphatase receptor type R JBrowse link 12 68,148,200 68,430,618 RGD:9068941
G RANBP9 RAN binding protein 9 JBrowse link 6 13,466,063 13,556,303 RGD:9068941
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 102,698,970 102,861,482 RGD:9068941
G RGS14 regulator of G protein signaling 14 JBrowse link 5 172,659,323 172,674,084 RGD:9068941
G RPS6KA6 ribosomal protein S6 kinase A6 JBrowse link X 73,131,457 73,261,906 RGD:9068941
G SEMA6A semaphorin 6A JBrowse link 5 111,793,272 111,924,937 RGD:9068941
G SIRPA signal regulatory protein alpha JBrowse link 20 2,006,994 2,052,894 RGD:9068941
G SIRT3 sirtuin 3 JBrowse link 11 210,052 233,969 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 17 68,694,468 68,715,157 RGD:9068941
G SMAD4 SMAD family member 4 JBrowse link 18 44,402,112 44,456,779 RGD:9068941
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 15 17,182,976 17,286,566 RGD:9068941
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 2A 65,380,608 65,503,139 RGD:9068941
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 19 35,482,436 35,490,745 RGD:9068941
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 4 115,570,788 115,578,824 RGD:9068941
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 13 61,569,658 61,574,817 RGD:9068941
G SYNJ2BP synaptojanin 2 binding protein JBrowse link 14 50,958,861 51,009,395 RGD:9068941
G TBC1D10C TBC1 domain family member 10C JBrowse link 11 62,762,075 62,768,569 RGD:9068941
G TIMP3 TIMP metallopeptidase inhibitor 3 JBrowse link 22 13,811,297 13,872,799 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 9 88,827,495 88,840,458 RGD:9068941
G TNIP1 TNFAIP3 interacting protein 1 JBrowse link 5 146,457,347 146,514,515 RGD:9068941
G VRK3 VRK serine/threonine kinase 3 JBrowse link 19 46,988,994 47,037,962 RGD:9068941
G WNK2 WNK lysine deficient protein kinase 2 JBrowse link 9 64,307,620 64,444,141 RGD:9068941
G XBP1 X-box binding protein 1 JBrowse link 22 9,863,479 9,869,491 RGD:9068941
negative regulation of ERK5 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 17 31,729,429 31,736,216 RGD:9068941
negative regulation of hippo signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AJUBA ajuba LIM protein JBrowse link 14 3,791,309 3,802,763 RGD:9068941
G DLG5 discs large MAGUK scaffold protein 5 JBrowse link 10 74,311,249 74,447,312 RGD:9068941
G LIMD1 LIM domains containing 1 JBrowse link 3 45,500,413 45,587,850 RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 6 35,586,847 35,683,041 RGD:9068941
G MARK3 microtubule affinity regulating kinase 3 JBrowse link 14 84,012,076 84,130,136 RGD:9068941
G VGLL4 vestigial like family member 4 JBrowse link 3 11,489,805 11,654,507 RGD:9068941
G WTIP WT1 interacting protein JBrowse link 19 31,436,223 31,461,262 RGD:9068941
G WWC1 WW and C2 domain containing 1 JBrowse link 5 163,654,833 163,835,006 RGD:9068941
G WWC2 WW and C2 domain containing 2 JBrowse link 4 175,280,079 175,495,156 RGD:9068941
G WWC3 WWC family member 3 JBrowse link X 2,645,114 2,774,764 RGD:9068941
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 1 6,722,260 6,745,915 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 1 19,583,330 19,601,248 RGD:9068941
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENO1 enolase 1 JBrowse link 1 7,619,490 7,637,558 RGD:9068941
G HYOU1 hypoxia up-regulated 1 JBrowse link 11 113,882,418 113,895,438 RGD:9068941
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 45,337,117 45,438,826 RGD:9068941
G NOL3 nucleolar protein 3 JBrowse link 16 47,516,156 47,521,441 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 1 19,583,330 19,601,248 RGD:9068941
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 12 38,986,844 39,010,307 RGD:9068941
negative regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 101,834,189 102,005,811 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 183,876,051 183,889,723 RGD:9068941
G ASH1L ASH1 like histone lysine methyltransferase JBrowse link 1 130,679,868 130,906,918 RGD:9068941
G CACTIN cactin, spliceosome C complex subunit JBrowse link 19 2,636,129 2,652,332 RGD:9068941
G CASP8 caspase 8 JBrowse link 2B 88,490,611 88,542,132 RGD:9068941
G CCDC22 coiled-coil domain containing 22 JBrowse link X 41,535,439 41,550,547 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 92,696,798 92,912,425 RGD:9068941
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 16 3,351,825 3,381,914 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 6 149,507,599 149,918,523 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 62,942,756 62,945,701 RGD:9068941
G HDAC1 histone deacetylase 1 JBrowse link 1 31,578,373 31,619,970 RGD:9068941
G LOC100969375 caspase recruitment domain-containing protein 8 JBrowse link 19 45,204,735 45,256,481 RGD:9068941
G MAPKBP1 mitogen-activated protein kinase binding protein 1 JBrowse link 15 20,713,859 20,768,224 RGD:9068941
G NFKBID NFKB inhibitor delta JBrowse link 19 32,805,772 32,817,778 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 16 2,463,940 2,487,961 RGD:9068941
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 19 50,735,124 50,765,556 RGD:9068941
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 11 274,904 281,590 RGD:9068941
G NLRX1 NLR family member X1 JBrowse link 11 114,007,415 114,022,712 RGD:9068941
G NR1D1 nuclear receptor subfamily 1 group D member 1 JBrowse link 17 17,188,390 17,196,315 RGD:9068941
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 98,052,778 98,144,085 RGD:9068941
G OLFM4 olfactomedin 4 JBrowse link 13 34,066,155 34,089,468 RGD:9068941
G OPTN optineurin JBrowse link 10 13,104,335 13,142,725 RGD:9068941
G OTUD7B OTU deubiquitinase 7B JBrowse link 1 125,282,599 125,355,441 RGD:9068941
G PER1 period circadian regulator 1 JBrowse link 17 43,502,080 43,518,098 RGD:9068941
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A JBrowse link 14 40,853,227 40,906,044 RGD:9068941
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B JBrowse link 2A 44,254,168 44,325,132 RGD:9068941
G PYCARD PYD and CARD domain containing JBrowse link 16 23,764,386 23,765,732 RGD:9068941
G RHOA ras homolog family member A JBrowse link 3 49,282,009 49,339,887 RGD:9068941
G RHOH ras homolog family member H JBrowse link 4 34,517,487 34,569,934 RGD:9068941
G RIOK3 RIO kinase 3 JBrowse link 18 16,703,893 16,734,160 RGD:9068941
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 6 2,893,802 2,943,162 RGD:9068941
G RORA RAR related orphan receptor A JBrowse link 15 39,461,553 40,200,118 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G STAT1 signal transducer and activator of transcription 1 JBrowse link 2B 78,270,642 78,316,074 RGD:9068941
G TANK TRAF family member associated NFKB activator JBrowse link 2B 48,426,036 48,525,265 RGD:9068941
G TLE1 TLE family member 1, transcriptional corepressor JBrowse link 9 43,150,356 43,258,551 RGD:9068941
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 6 135,617,465 135,634,085 RGD:9068941
G TNIP1 TNFAIP3 interacting protein 1 JBrowse link 5 146,457,347 146,514,515 RGD:9068941
G TNIP3 TNFAIP3 interacting protein 3 JBrowse link 4 113,343,082 113,428,022 RGD:9068941
G TRIM39 tripartite motif containing 39 JBrowse link 6 30,104,381 30,121,649 RGD:9068941
G TRIM59 tripartite motif containing 59 JBrowse link 3 157,458,982 157,471,521 RGD:9068941
G USP10 ubiquitin specific peptidase 10 JBrowse link 16 65,367,463 65,447,549 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 36,743,341 36,753,261 RGD:9068941
G ZMYND11 zinc finger MYND-type containing 11 JBrowse link 10 139,879 264,711 RGD:9068941
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRPA signal regulatory protein alpha JBrowse link 20 2,006,994 2,052,894 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2 BCL2 apoptosis regulator JBrowse link 18 56,481,212 56,679,012 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 20 27,955,688 28,015,950 RGD:9068941
G BCL2L10 BCL2 like 10 JBrowse link 15 31,049,509 31,057,273 RGD:9068941
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 33,780,381 33,796,829 RGD:9068941
G FIGNL1 fidgetin like 1 JBrowse link 7 51,080,052 51,093,694 RGD:9068941
G G2E3 G2/M-phase specific E3 ubiquitin protein ligase JBrowse link 14 11,338,212 11,398,545 RGD:9068941
G GCG glucagon JBrowse link 2B 49,436,379 49,446,559 RGD:9068941
G HDAC1 histone deacetylase 1 JBrowse link 1 31,578,373 31,619,970 RGD:9068941
G HDAC2 histone deacetylase 2 JBrowse link 6 111,731,139 111,761,826 RGD:9068941
G HELLS helicase, lymphoid specific JBrowse link 10 91,282,330 91,344,156 RGD:9068941
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 16 37,210,170 37,221,961 RGD:9068941
G IVNS1ABP influenza virus NS1A binding protein JBrowse link 1 160,822,327 160,843,022 RGD:9068941
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 11 45,839,754 45,860,615 RGD:9068941
G MMP9 matrix metallopeptidase 9 JBrowse link 20 42,346,305 42,354,018 RGD:9068941
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 19 18,954,214 18,966,634 RGD:9068941
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 JBrowse link 11 47,528,680 47,534,206 RGD:9068941
G NOC2L NOC2 like nucleolar associated transcriptional repressor RGD:9068941
G NOL3 nucleolar protein 3 JBrowse link 16 47,516,156 47,521,441 RGD:9068941
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 3 190,890,242 190,995,133 RGD:9068941
G PARL presenilin associated rhomboid like JBrowse link 3 180,862,434 180,921,197 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 1 19,583,330 19,601,248 RGD:9068941
G PLAUR plasminogen activator, urokinase receptor JBrowse link 19 40,588,100 40,616,479 RGD:9068941
G PPIF peptidylprolyl isomerase F JBrowse link 10 75,860,197 75,868,098 RGD:9068941
G RTKN2 rhotekin 2 JBrowse link 10 58,707,821 58,793,899 RGD:9068941
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 33,667,614 33,727,126 RGD:9068941
G URI1 URI1 prefoldin like chaperone JBrowse link 19 26,865,190 26,939,510 RGD:9068941
G VDAC2 voltage dependent anion channel 2 JBrowse link 10 71,739,395 71,763,835 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMC10 armadillo repeat containing 10 JBrowse link 7 95,049,105 95,073,466 RGD:9068941
G CEP63 centrosomal protein 63 JBrowse link 3 131,532,450 131,609,240 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 66,322,340 66,357,010 RGD:9068941
G MDM4 MDM4 regulator of p53 JBrowse link 1 180,117,364 180,151,144 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
G PTTG1IP PTTG1 interacting protein JBrowse link 21 31,143,600 31,169,231 RGD:9068941
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 8 98,854,101 98,890,365 RGD:9068941
G RRN3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 16 13,664,478 13,700,942 RGD:9068941
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 1 119,224,304 119,267,986 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACKR3 atypical chemokine receptor 3 JBrowse link 2B 123,795,664 123,810,067 RGD:9068941
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,944,259 26,009,317 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 20 27,955,688 28,015,950 RGD:9068941
G BID BH3 interacting domain death agonist JBrowse link 22 1,164,787 1,205,051 RGD:9068941
G CCAR2 cell cycle and apoptosis regulator 2 JBrowse link 8 21,854,803 21,870,556 RGD:9068941
G CDKN2D cyclin dependent kinase inhibitor 2D JBrowse link 19 10,118,302 10,120,957 RGD:9068941
G CLU clusterin JBrowse link 8 26,867,973 26,884,838 RGD:9068941
G CXCL12 C-X-C motif chemokine ligand 12 JBrowse link 10 41,296,975 41,384,864 RGD:9068941
G DDIAS DNA damage induced apoptosis suppressor JBrowse link 11 77,967,057 77,999,829 RGD:9068941
G SFRP2 secreted frizzled related protein 2 JBrowse link 4 146,123,075 146,131,543 RGD:9068941
G SNAI1 snail family transcriptional repressor 1 JBrowse link 20 46,321,075 46,328,865 RGD:9068941
G SNAI2 snail family transcriptional repressor 2 JBrowse link 8 45,341,857 45,345,544 RGD:9068941
G TMEM161A transmembrane protein 161A JBrowse link 19 18,557,799 18,576,722 RGD:9068941
G TPT1 tumor protein, translationally-controlled 1 JBrowse link 13 26,504,747 26,509,160 RGD:9068941
G TRIM32 tripartite motif containing 32 JBrowse link 9 87,819,723 87,838,684 RGD:9068941
G USP47 ubiquitin specific peptidase 47 JBrowse link 11 12,009,770 12,127,425 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,944,259 26,009,317 RGD:9068941
G BCL2L12 BCL2 like 12 JBrowse link 19 46,679,749 46,688,539 RGD:9068941
G CD44 CD44 molecule (Indian blood group) JBrowse link 11 35,110,732 35,258,238 RGD:9068941
G CD74 CD74 molecule JBrowse link 5 145,825,635 145,836,916 RGD:9068941
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 15 22,732,742 22,737,522 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 1 22,205,624 22,269,571 RGD:9068941
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 2B 47,004,211 47,059,901 RGD:9068941
G MIF macrophage migration inhibitory factor JBrowse link 22 4,646,986 4,647,831 RGD:9068941
G MUC1 mucin 1, cell surface associated JBrowse link 1 130,533,508 130,537,866 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 12 118,025,599 118,028,045 RGD:9068941
G ZNF385A zinc finger protein 385A JBrowse link 12 34,353,975 34,376,172 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 13 12,412,826 12,438,563 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 1 19,583,330 19,601,248 RGD:9068941
G TRAP1 TNF receptor associated protein 1 JBrowse link 16 2,578,483 2,637,996 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 1 131,282,514 131,326,535 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 14 76,832,833 76,873,860 RGD:9068941
G EPO erythropoietin JBrowse link 7 92,747,671 92,750,886 RGD:9068941
G PTGER2 prostaglandin E receptor 2 JBrowse link 14 32,910,755 32,926,138 RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 162,205,534 162,214,130 RGD:9068941
G YBX3 Y-box binding protein 3 JBrowse link 12 10,728,049 10,752,267 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BDKRB2 bradykinin receptor B2 JBrowse link 14 76,832,833 76,873,860 RGD:9068941
negative regulation of JNK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIDA axin interactor, dorsalization associated JBrowse link 1 198,341,375 198,385,682 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 85,417,229 85,444,722 RGD:9068941
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 39,395,550 39,417,063 RGD:9068941
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 16 31,004,393 31,064,546 RGD:9068941
G DACT1 dishevelled binding antagonist of beta catenin 1 JBrowse link 14 39,231,910 39,242,353 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 197,293,039 197,333,828 RGD:9068941
G DUSP19 dual specificity phosphatase 19 JBrowse link 2B 70,347,712 70,371,852 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 17 13,618,860 13,631,743 RGD:9068941
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 38,462,521 38,478,882 RGD:9068941
G FKTN fukutin JBrowse link 9 76,723,071 76,821,611 RGD:9068941
G GPS2 G protein pathway suppressor 2 JBrowse link 17 7,346,766 7,349,682 RGD:9068941
G HDAC3 histone deacetylase 3 JBrowse link 5 136,981,790 136,997,786 RGD:9068941
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 20 30,690,172 30,840,504 RGD:9068941
G KLHL31 kelch like family member 31 JBrowse link 6 53,201,483 53,351,320 RGD:9068941
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 11 45,839,754 45,860,615 RGD:9068941
G MARVELD3 MARVEL domain containing 3 JBrowse link 16 53,369,080 53,385,031 RGD:9068941
G MECOM MDS1 and EVI1 complex locus JBrowse link 3 166,099,530 166,677,739 RGD:9068941
G MEN1 menin 1 JBrowse link 11 60,159,009 60,166,222 RGD:9068941
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 34,934,452 35,121,195 RGD:9068941
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 JBrowse link 17 2,584,349 2,676,928 RGD:9068941
G PER1 period circadian regulator 1 JBrowse link 17 43,502,080 43,518,098 RGD:9068941
G SFRP4 secreted frizzled related protein 4 JBrowse link 7 38,542,105 38,553,008 RGD:9068941
G SH3RF2 SH3 domain containing ring finger 2 JBrowse link 5 141,386,060 141,530,993 RGD:9068941
G SIRPA signal regulatory protein alpha JBrowse link 20 2,006,994 2,052,894 RGD:9068941
G TAOK3 TAO kinase 3 JBrowse link 12 115,730,619 115,954,149 RGD:9068941
G ZMYND11 zinc finger MYND-type containing 11 JBrowse link 10 139,879 264,711 RGD:9068941
negative regulation of JUN kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIDA axin interactor, dorsalization associated JBrowse link 1 198,341,375 198,385,682 RGD:9068941
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 9 32,800,077 32,814,745 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 197,293,039 197,333,828 RGD:9068941
G DUSP19 dual specificity phosphatase 19 JBrowse link 2B 70,347,712 70,371,852 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 62,942,756 62,945,701 RGD:9068941
G HIPK3 homeodomain interacting protein kinase 3 JBrowse link 11 33,230,731 33,330,617 RGD:9068941
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 11 45,839,754 45,860,615 RGD:9068941
G NPPA natriuretic peptide A JBrowse link 1 10,608,025 10,610,287 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 88,685,736 88,743,164 RGD:9068941
G SFRP1 secreted frizzled related protein 1 JBrowse link 8 40,507,027 40,555,053 RGD:9068941
G SFRP2 secreted frizzled related protein 2 JBrowse link 4 146,123,075 146,131,543 RGD:9068941
G SFRP5 secreted frizzled related protein 5 JBrowse link 10 94,383,269 94,389,053 RGD:9068941
G TP73 tumor protein p73 JBrowse link 1 2,323,399 2,405,295 RGD:9068941
negative regulation of MAP kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 183,876,051 183,889,723 RGD:9068941
G AGT angiotensinogen JBrowse link 1 206,252,141 206,263,830 RGD:9068941
G APOE apolipoprotein E JBrowse link 19 41,853,669 41,857,252 RGD:9068941
G BMP4 bone morphogenetic protein 4 JBrowse link 14 34,542,132 34,549,286 RGD:9068941
G BMP7 bone morphogenetic protein 7 JBrowse link 20 53,509,484 53,606,889 RGD:9068941
G CAV1 caveolin 1 JBrowse link 7 108,497,125 108,533,090 RGD:9068941
G CAV3 caveolin 3 JBrowse link 3 8,684,829 8,697,731 RGD:9068941
G CBLC Cbl proto-oncogene C JBrowse link 19 41,726,272 41,748,829 RGD:9068941
G CD300A CD300a molecule JBrowse link 17 68,403,647 68,426,285 RGD:9068941
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 JBrowse link 17 9,556,313 9,567,099 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 92,696,798 92,912,425 RGD:9068941
G DEFB114 defensin beta 114 JBrowse link 6 49,527,541 49,531,451 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 5 168,121,536 168,124,671 RGD:9068941
G DUSP7 dual specificity phosphatase 7 JBrowse link 3 51,990,115 51,997,627 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 116,943,205 117,215,001 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 62,942,756 62,945,701 RGD:9068941
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 39,936,630 39,961,519 RGD:9068941
G HYAL2 hyaluronidase 2 JBrowse link 3 50,243,926 50,248,972 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 89,216,313 89,223,358 RGD:9068941
G INPP5K inositol polyphosphate-5-phosphatase K JBrowse link 17 1,477,511 1,499,765 RGD:9068941
G INPPL1 inositol polyphosphate phosphatase like 1 JBrowse link 11 67,302,066 67,317,785 RGD:9068941
G IRAK3 interleukin 1 receptor associated kinase 3 JBrowse link 12 22,661,613 22,721,203 RGD:9068941
G KNG1 kininogen 1 JBrowse link 3 183,751,598 183,778,655 RGD:9068941
G LOC100973655 protein fem-1 homolog A JBrowse link 21 468,156 495,596 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 52,318,497 52,455,741 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 17 31,729,429 31,736,216 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 17 25,425,081 25,703,689 RGD:9068941
G NUP62 nucleoporin 62 JBrowse link 19 46,919,731 46,942,318 RGD:9068941
G PAQR3 progestin and adipoQ receptor family member 3 JBrowse link 4 45,255,403 45,279,319 RGD:9068941
G PRKCD protein kinase C delta JBrowse link 3 53,104,137 53,135,588 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 46,854,918 46,929,509 RGD:9068941
G PTPN5 protein tyrosine phosphatase non-receptor type 5 JBrowse link 11 18,758,285 18,822,845 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 12 7,075,879 7,093,041 RGD:9068941
G PTPRJ protein tyrosine phosphatase receptor type J JBrowse link 11 47,941,134 48,130,538 RGD:9068941
G RGS14 regulator of G protein signaling 14 JBrowse link 5 172,659,323 172,674,084 RGD:9068941
G RGS2 regulator of G protein signaling 2 JBrowse link 1 168,273,112 168,276,348 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 12 108,977,344 109,024,029 RGD:9068941
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 11 6,521,812 6,526,349 RGD:9068941
G SORL1 sortilin related receptor 1 JBrowse link 11 116,297,014 116,477,399 RGD:9068941
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 4 115,570,788 115,578,824 RGD:9068941
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 13 61,569,658 61,574,817 RGD:9068941
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 5 137,667,280 137,683,578 RGD:9068941
G STK38 serine/threonine kinase 38 JBrowse link 6 36,056,585 36,110,531 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 4 35,580,755 35,592,314 RGD:9068941
negative regulation of MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APC APC regulator of WNT signaling pathway JBrowse link 5 108,070,697 108,208,273 RGD:9068941
G ASH1L ASH1 like histone lysine methyltransferase JBrowse link 1 130,679,868 130,906,918 RGD:9068941
G CAV1 caveolin 1 JBrowse link 7 108,497,125 108,533,090 RGD:9068941
G CAV3 caveolin 3 JBrowse link 3 8,684,829 8,697,731 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 3 49,396,180 49,464,689 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 5 168,121,536 168,124,671 RGD:9068941
G DUSP16 dual specificity phosphatase 16 JBrowse link 12 12,497,185 12,585,591 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 17 13,618,860 13,631,743 RGD:9068941
G EFNA1 ephrin A1 JBrowse link 1 130,475,128 130,482,531 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 77,332,926 77,648,474 RGD:9068941
G LEMD2 LEM domain nuclear envelope protein 2 JBrowse link 6 33,344,372 33,363,143 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 17 25,425,081 25,703,689 RGD:9068941
G NF2 neurofibromin 2 JBrowse link 22 10,648,022 10,738,167 RGD:9068941
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 11 274,904 281,590 RGD:9068941
G P2RX7 purinergic receptor P2X 7 JBrowse link 12 118,731,761 118,786,039 RGD:9068941
G PEBP1 phosphatidylethanolamine binding protein 1 JBrowse link 12 115,716,953 115,726,412 RGD:9068941
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 19 17,632,265 17,649,664 RGD:9068941
G PPEF2 protein phosphatase with EF-hand domain 2 JBrowse link 4 48,308,761 48,345,861 RGD:9068941
G PRDM15 PR/SET domain 15 JBrowse link 21 28,122,173 28,202,837 RGD:9068941
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 97,182,090 97,189,523 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 12 7,075,879 7,093,041 RGD:9068941
G RNF149 ring finger protein 149 RGD:9068941
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 15 17,182,976 17,286,566 RGD:9068941
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1QBP complement C1q binding protein JBrowse link 17 5,481,114 5,487,482 RGD:9068941
G DHX58 DExH-box helicase 58 JBrowse link 17 15,203,216 15,214,559 RGD:9068941
G RIOK3 RIO kinase 3 JBrowse link 18 16,703,893 16,734,160 RGD:9068941
G TKFC triokinase and FMN cyclase JBrowse link 11 56,633,046 56,648,276 RGD:9068941
negative regulation of NIK/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADGRG3 adhesion G protein-coupled receptor G3 JBrowse link 16 37,945,248 37,966,293 RGD:9068941
G ADIPOR1 adiponectin receptor 1 JBrowse link 1 178,542,496 178,560,055 RGD:9068941
G C1QTNF3 C1q and TNF related 3 JBrowse link 5 76,292,679 76,325,064 RGD:9068941
G CAPN1 calpain 1 JBrowse link 11 60,545,837 60,576,631 RGD:9068941
G CCN3 cellular communication network factor 3 JBrowse link 8 116,105,935 116,114,241 RGD:9068941
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 16 31,004,393 31,064,546 RGD:9068941
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 33,780,381 33,796,829 RGD:9068941
G FBXW11 F-box and WD repeat domain containing 11 JBrowse link 5 167,207,643 167,354,730 RGD:9068941
G HDAC7 histone deacetylase 7 JBrowse link 12 40,913,301 40,950,542 RGD:9068941
G LITAF lipopolysaccharide induced TNF factor JBrowse link 16 10,488,738 10,527,843 RGD:9068941
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 11 73,128,457 73,140,344 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 16 2,463,940 2,487,961 RGD:9068941
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 19 50,735,124 50,765,556 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 223,052,307 223,084,736 RGD:9068941
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A JBrowse link 14 40,853,227 40,906,044 RGD:9068941
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B JBrowse link 2A 44,254,168 44,325,132 RGD:9068941
G PYDC2 pyrin domain containing 2 JBrowse link 3 188,753,168 188,753,477 RGD:9068941
G RASSF2 Ras association domain family member 2 JBrowse link 20 4,804,802 4,845,633 RGD:9068941
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 61,012,839 61,022,225 RGD:9068941
G TMSB4X thymosin beta 4 X-linked JBrowse link X 5,587,242 5,589,417 RGD:9068941
G TSPAN6 tetraspanin 6 JBrowse link X 89,840,067 89,848,114 RGD:9068941
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats JBrowse link 15 49,607,308 49,711,188 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 36,743,341 36,753,261 RGD:9068941
negative regulation of nitric oxide mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 1 179,231,712 179,348,759 RGD:9068941
G SPINK1 serine peptidase inhibitor Kazal type 1 JBrowse link 5 143,273,137 143,287,745 RGD:9068941
G THBS1 thrombospondin 1 JBrowse link 15 18,521,802 18,538,172 RGD:9068941
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 9 32,800,077 32,814,745 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 6,722,260 6,745,915 RGD:9068941
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 6 135,617,465 135,634,085 RGD:9068941
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERBIN erbb2 interacting protein JBrowse link 5 47,929,305 48,081,381 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 88,685,736 88,743,164 RGD:9068941
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 6 135,617,465 135,634,085 RGD:9068941
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAG5 BAG cochaperone 5 JBrowse link 14 84,182,879 84,189,180 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 3 49,280,038 49,281,455 RGD:9068941
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 7 67,716,021 67,717,762 RGD:9068941
G LOC100978332 pantetheinase JBrowse link 6 130,459,268 130,491,167 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 17 31,729,429 31,736,216 RGD:9068941
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2B 64,509,446 64,544,600 RGD:9068941
G NME5 NME/NM23 family member 5 JBrowse link 5 133,493,930 133,517,906 RGD:9068941
G NOL3 nucleolar protein 3 JBrowse link 16 47,516,156 47,521,441 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 6 157,562,814 157,610,155 RGD:9068941
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 42,295,691 42,348,478 RGD:9068941
G NONO non-POU domain containing octamer binding JBrowse link X 60,547,277 60,564,845 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 6,722,260 6,745,915 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
negative regulation of p38MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 16 31,004,393 31,064,546 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 3 194,386,263 194,648,015 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 5 168,121,536 168,124,671 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 197,293,039 197,333,828 RGD:9068941
G EZR ezrin JBrowse link 6 156,656,146 156,709,986 RGD:9068941
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 13 12,412,826 12,438,563 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 88,685,736 88,743,164 RGD:9068941
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,215,215 26,227,261 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 17 27,522,647 27,530,767 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 92,696,798 92,912,425 RGD:9068941
G INPP5E inositol polyphosphate-5-phosphatase E JBrowse link 9 107,502,838 107,516,325 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 9 78,634,545 78,639,447 RGD:9068941
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 34,934,452 35,121,195 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 16 2,463,940 2,487,961 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 44,739,739 44,751,303 RGD:9068941
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 1 203,605,558 203,781,491 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 22 12,305,518 12,316,434 RGD:9068941
G SERPINE2 serpin family E member 2 JBrowse link 2B 111,221,317 111,285,491 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 17 68,694,468 68,715,157 RGD:9068941
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 16 664,310 676,640 RGD:9068941
G STAMBP STAM binding protein JBrowse link 2A 73,900,128 73,936,571 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 7 19,761,041 19,765,665 RGD:9068941
negative regulation of protein kinase B signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BANK1 B cell scaffold protein with ankyrin repeats 1 JBrowse link 4 94,216,751 94,507,965 RGD:9068941
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,215,215 26,227,261 RGD:9068941
G CAVIN3 caveolae associated protein 3 JBrowse link 11 6,451,364 6,453,206 RGD:9068941
G CIB1 calcium and integrin binding 1 JBrowse link 15 68,919,377 68,923,213 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 17 27,522,647 27,530,767 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 3 49,396,180 49,464,689 RGD:9068941
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 31,406,332 31,410,293 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 3 194,386,263 194,648,015 RGD:9068941
G DRD2 dopamine receptor D2 JBrowse link 11 108,289,838 108,357,174 RGD:9068941
G DRD3 dopamine receptor D3 JBrowse link 3 111,265,834 111,317,176 RGD:9068941
G EPHA2 EPH receptor A2 JBrowse link 1 15,259,915 15,292,983 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G HYAL2 hyaluronidase 2 JBrowse link 3 50,243,926 50,248,972 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 77,332,926 77,648,474 RGD:9068941
G INPP5K inositol polyphosphate-5-phosphatase K JBrowse link 17 1,477,511 1,499,765 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 9 78,634,545 78,639,447 RGD:9068941
G LEMD2 LEM domain nuclear envelope protein 2 JBrowse link 6 33,344,372 33,363,143 RGD:9068941
G LMBRD1 LMBR1 domain containing 1 JBrowse link 6 67,515,861 67,638,039 RGD:9068941
G LOC100967334 G-protein coupled estrogen receptor 1 JBrowse link 7 1,245,873 1,251,915 RGD:9068941
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 7 69,943,704 71,395,176 RGD:9068941
G MMP3 matrix metallopeptidase 3 JBrowse link 11 97,776,729 97,784,549 RGD:9068941
G MSTN myostatin JBrowse link 2B 77,364,927 77,452,426 RGD:9068941
G MTM1 myotubularin 1 JBrowse link X 140,218,742 140,323,495 RGD:9068941
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 1 19,454,792 19,463,527 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 44,739,739 44,751,303 RGD:9068941
G OTUD3 OTU deubiquitinase 3 JBrowse link 1 18,836,697 18,867,568 RGD:9068941
G PDCD6 programmed cell death 6 JBrowse link 5 250,025 291,055 RGD:9068941
G PHLDA3 pleckstrin homology like domain family A member 3 JBrowse link 1 177,063,775 177,067,714 RGD:9068941
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 18 56,084,851 56,338,551 RGD:9068941
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 6 51,166,516 51,635,057 RGD:9068941
G PLEKHA1 pleckstrin homology domain containing A1 JBrowse link 10 118,942,896 119,001,185 RGD:9068941
G POU5F1 POU class 5 homeobox 1 JBrowse link 6 30,910,421 30,916,465 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 84,587,841 84,689,043 RGD:9068941
G PTPRJ protein tyrosine phosphatase receptor type J JBrowse link 11 47,941,134 48,130,538 RGD:9068941
G RACK1 receptor for activated C kinase 1 JBrowse link 5 176,462,991 176,470,153 RGD:9068941
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 102,698,970 102,861,482 RGD:9068941
G SFRP5 secreted frizzled related protein 5 JBrowse link 10 94,383,269 94,389,053 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 12 108,977,344 109,024,029 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 17 68,694,468 68,715,157 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
G XDH xanthine dehydrogenase JBrowse link 2A 31,356,011 31,435,111 RGD:9068941
negative regulation of protein kinase C signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGKD diacylglycerol kinase delta JBrowse link 2B 120,582,278 120,701,165 RGD:9068941
G DGKG diacylglycerol kinase gamma JBrowse link 3 183,164,835 183,392,282 RGD:9068941
G GPD1L glycerol-3-phosphate dehydrogenase 1 like JBrowse link 3 32,026,586 32,088,512 RGD:9068941
G MYADM myeloid associated differentiation marker JBrowse link 19 50,807,615 50,817,196 RGD:9068941
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 18 56,084,851 56,338,551 RGD:9068941
negative regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 5 137,014,286 137,042,786 RGD:9068941
G ARHGAP24 Rho GTPase activating protein 24 JBrowse link 4 77,788,074 78,316,357 RGD:9068941
G ARHGAP44 Rho GTPase activating protein 44 JBrowse link 17 38,657,824 38,859,591 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 17 25,425,081 25,703,689 RGD:9068941
G STMN3 stathmin 3 RGD:9068941
negative regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DAB2IP DAB2 interacting protein JBrowse link 9 92,696,798 92,912,425 RGD:9068941
G DGKZ diacylglycerol kinase zeta JBrowse link 11 46,291,592 46,339,127 RGD:9068941
G EPHB2 EPH receptor B2 JBrowse link 1 21,895,961 22,107,649 RGD:9068941
G FBP1 fructose-bisphosphatase 1 JBrowse link 9 65,695,082 65,731,628 RGD:9068941
G LOC100993573 rab5 GDP/GTP exchange factor JBrowse link 7 59,268,053 59,344,555 RGD:9068941
G LZTR1 leucine zipper like transcription regulator 1 JBrowse link 22 3,206,019 3,223,050 RGD:9068941
G MAPKAP1 MAPK associated protein 1 JBrowse link 9 96,561,157 96,825,478 RGD:9068941
G MFN2 mitofusin 2 JBrowse link 1 10,729,933 10,764,865 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 17 25,425,081 25,703,689 RGD:9068941
G NUP62 nucleoporin 62 JBrowse link 19 46,919,731 46,942,318 RGD:9068941
G PPP2CB protein phosphatase 2 catalytic subunit beta JBrowse link 8 30,099,605 30,126,917 RGD:9068941
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 102,698,970 102,861,482 RGD:9068941
G RASAL3 RAS protein activator like 3 JBrowse link 19 14,982,964 14,995,889 RGD:9068941
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 4 115,570,788 115,578,824 RGD:9068941
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 13 61,569,658 61,574,817 RGD:9068941
G STAMBP STAM binding protein JBrowse link 2A 73,900,128 73,936,571 RGD:9068941
G SYNGAP1 synaptic Ras GTPase activating protein 1 JBrowse link 6 32,999,408 33,033,067 RGD:9068941
G TGFB2 transforming growth factor beta 2 JBrowse link 1 193,907,398 194,005,800 RGD:9068941
G TIMP2 TIMP metallopeptidase inhibitor 2 JBrowse link 17 72,928,692 73,001,892 RGD:9068941
G TNK1 tyrosine kinase non receptor 1 JBrowse link 17 7,403,403 7,423,942 RGD:9068941
G TRIM67 tripartite motif containing 67 JBrowse link 1 206,710,490 206,770,111 RGD:9068941
negative regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 1 154,586,423 154,711,621 RGD:9068941
G ADRA1A adrenoceptor alpha 1A JBrowse link 8 25,947,996 26,138,022 RGD:9068941
G ADRA1B adrenoceptor alpha 1B JBrowse link 5 155,307,148 155,363,785 RGD:9068941
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 5 137,014,286 137,042,786 RGD:9068941
G ARHGAP35 Rho GTPase activating protein 35 JBrowse link 19 43,850,692 43,994,487 RGD:9068941
G ARHGAP42 Rho GTPase activating protein 42 JBrowse link 11 95,655,874 95,962,003 RGD:9068941
G BCL6 BCL6 transcription repressor JBrowse link 3 184,748,135 184,772,375 RGD:9068941
G CCDC125 coiled-coil domain containing 125 JBrowse link 5 44,667,688 44,717,872 RGD:9068941
G CUL3 cullin 3 JBrowse link 2B 111,714,533 111,827,080 RGD:9068941
G DLC1 DLC1 Rho GTPase activating protein JBrowse link 8 12,282,190 12,809,770 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G HEG1 heart development protein with EGF like domains 1 JBrowse link 3 122,091,832 122,204,436 RGD:9068941
G ITGA3 integrin subunit alpha 3 JBrowse link 17 44,145,974 44,181,343 RGD:9068941
G ITGB1 integrin subunit beta 1 JBrowse link 10 33,023,573 33,081,384 RGD:9068941
G KANK1 KN motif and ankyrin repeat domains 1 JBrowse link 9 550,713 556,230 RGD:9068941
G KCTD13 potassium channel tetramerization domain containing 13 RGD:9068941
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 7 108,646,278 108,772,238 RGD:9068941
G MYOC myocilin JBrowse link 1 147,128,541 147,146,227 RGD:9068941
G RASIP1 Ras interacting protein 1 JBrowse link 19 45,720,179 45,740,131 RGD:9068941
G RIPOR1 RHO family interacting cell polarization regulator 1 JBrowse link 16 47,872,769 47,890,776 RGD:9068941
G RIPOR2 RHO family interacting cell polarization regulator 2 JBrowse link 6 24,642,239 24,768,074 RGD:9068941
G SCAI suppressor of cancer cell invasion JBrowse link 9 96,063,149 96,264,502 RGD:9068941
G STMN1 stathmin 1 JBrowse link 1 25,159,241 25,165,535 RGD:9068941
G TNFAIP1 TNF alpha induced protein 1 JBrowse link 17 28,427,448 28,438,826 RGD:9068941
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1QBP complement C1q binding protein JBrowse link 17 5,481,114 5,487,482 RGD:9068941
G DHX58 DExH-box helicase 58 JBrowse link 17 15,203,216 15,214,559 RGD:9068941
G GPATCH3 G-patch domain containing 3 JBrowse link 1 26,153,078 26,163,181 RGD:9068941
G NLRX1 NLR family member X1 JBrowse link 11 114,007,415 114,022,712 RGD:9068941
G NPLOC4 NPL4 homolog, ubiquitin recognition factor JBrowse link 17 76,012,756 76,092,901 RGD:9068941
G RNF125 ring finger protein 125 JBrowse link 18 25,227,353 25,297,186 RGD:9068941
G SEC14L1 SEC14 like lipid binding 1 JBrowse link 17 71,221,870 71,297,142 RGD:9068941
G UFD1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 22 2,209,590 2,238,449 RGD:9068941
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALM1 calmodulin 1 JBrowse link 14 71,015,099 71,026,322 RGD:9068941
G CALM2 calmodulin 2 JBrowse link 2A 47,274,722 47,290,861 RGD:9068941
G CALM3 calmodulin 3 JBrowse link 19 43,593,069 43,602,550 RGD:9068941
G CASQ2 calsequestrin 2 JBrowse link 1 86,795,392 86,864,196 RGD:9068941
G CLIC2 chloride intracellular channel 2 JBrowse link X 144,742,839 144,851,524 RGD:9068941
G FKBP1A FKBP prolyl isomerase 1A JBrowse link 20 1,519,330 1,548,473 RGD:9068941
G FKBP1B FKBP prolyl isomerase 1B JBrowse link 2A 24,047,287 24,065,765 RGD:9068941
G GSTM2 glutathione S-transferase mu 2 JBrowse link 1 112,043,201 112,050,810 RGD:9068941
G GSTO1 glutathione S-transferase omega 1 JBrowse link 10 100,853,682 100,866,892 RGD:9068941
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 4 80,295,243 80,365,271 RGD:9068941
G SRI sorcin JBrowse link 7 80,199,719 80,214,733 RGD:9068941
negative regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 15 22,732,742 22,737,522 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 66,322,340 66,357,010 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 44,739,739 44,751,303 RGD:9068941
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 17 21,696,808 21,779,878 RGD:9068941
G RNF34 ring finger protein 34 JBrowse link 12 118,998,436 119,022,823 RGD:9068941
G SENP2 SUMO specific peptidase 2 JBrowse link 3 182,606,922 182,655,518 RGD:9068941
negative regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGAP12 Rho GTPase activating protein 12 JBrowse link 10 31,932,294 32,061,450 RGD:9068941
G ARHGAP25 Rho GTPase activating protein 25 JBrowse link 2A 68,775,637 68,867,870 RGD:9068941
G CD2AP CD2 associated protein JBrowse link 6 47,065,284 47,210,746 RGD:9068941
G CGNL1 cingulin like 1 JBrowse link 15 36,344,222 36,518,235 RGD:9068941
G CYRIB CYFIP related Rac1 interactor B JBrowse link 8 126,478,020 126,653,936 RGD:9068941
G LOC100968722 pyridoxal phosphate phosphatase JBrowse link 22 18,552,737 18,585,014 RGD:9068941
G SLIT2 slit guidance ligand 2 JBrowse link 4 14,654,448 15,023,708 RGD:9068941
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 197,293,039 197,333,828 RGD:9068941
G FOXM1 forkhead box M1 JBrowse link 12 2,978,400 2,999,077 RGD:9068941
G FOXO1 forkhead box O1 JBrowse link 13 21,763,729 21,874,279 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 62,942,756 62,945,701 RGD:9068941
G IGBP1 immunoglobulin binding protein 1 JBrowse link X 59,401,426 59,434,363 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 124,387,561 124,393,551 RGD:9068941
G PBK PDZ binding kinase JBrowse link 8 27,084,789 27,112,986 RGD:9068941
G QARS1 glutaminyl-tRNA synthetase 1 JBrowse link 3 49,020,310 49,029,443 RGD:9068941
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1S1 AKT1 substrate 1 JBrowse link 19 46,882,073 46,890,404 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,436,580 13,547,135 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 17 27,522,647 27,530,767 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 10 68,796,712 68,798,840 RGD:9068941
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 22 12,774,147 12,929,261 RGD:9068941
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 8 116,563,935 116,743,843 RGD:9068941
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 6 143,179,097 143,525,223 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 5 127,070,906 127,219,548 RGD:9068941
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 39,118,330 39,130,768 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 116,943,205 117,215,001 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 42,295,691 42,348,478 RGD:9068941
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 12 109,416,610 109,471,729 RGD:9068941
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 15 58,402,688 58,445,461 RGD:9068941
G MTM1 myotubularin 1 JBrowse link X 140,218,742 140,323,495 RGD:9068941
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 3 50,273,611 50,277,175 RGD:9068941
G NPRL3 NPR3 like, GATOR1 complex subunit RGD:9068941
G PDCD6 programmed cell death 6 JBrowse link 5 250,025 291,055 RGD:9068941
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 5 69,581,748 69,620,721 RGD:9068941
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 1 55,928,577 55,998,628 RGD:9068941
G SH3BP4 SH3 domain binding protein 4 JBrowse link 2B 122,179,431 122,284,430 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G TBC1D7 TBC1 domain family member 7 JBrowse link 6 13,150,677 13,174,661 RGD:9068941
G TMEM127 transmembrane protein 127 JBrowse link 2A 103,049,655 103,065,116 RGD:9068941
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 19 3,658,205 3,674,237 RGD:9068941
G TSC1 TSC complex subunit 1 JBrowse link 9 104,007,708 104,060,938 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 15 21,899,611 22,064,606 RGD:9068941
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 6 42,150,409 42,282,486 RGD:9068941
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 11 103,109,979 103,256,405 RGD:9068941
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 7 104,786,390 104,905,357 RGD:9068941
G C12H12orf66 chromosome 12 C12orf66 homolog JBrowse link 12 24,691,658 24,721,618 RGD:9068941
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 22 11,321,259 11,325,787 RGD:9068941
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 RGD:9068941
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 22 12,774,147 12,929,261 RGD:9068941
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 12 2,933,227 2,980,509 RGD:9068941
G KPTN kaptin, actin binding protein JBrowse link 19 44,467,344 44,478,150 RGD:9068941
G RNF152 ring finger protein 152 JBrowse link 18 55,180,955 55,264,164 RGD:9068941
G SESN1 sestrin 1 JBrowse link 6 106,789,911 106,896,382 RGD:9068941
G SESN2 sestrin 2 JBrowse link 1 27,518,248 27,541,264 RGD:9068941
G SESN3 sestrin 3 JBrowse link 11 90,184,571 90,249,825 RGD:9068941
G SPAAR small regulatory polypeptide of amino acid response JBrowse link 9 35,760,064 35,762,224 RGD:9068941
G STK11 serine/threonine kinase 11 RGD:9068941
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 1 42,691,292 42,754,046 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TSPAN6 tetraspanin 6 JBrowse link X 89,840,067 89,848,114 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    cellular process 11599
      signal transduction 3789
        negative regulation of signal transduction 1149
          negative regulation of intracellular signal transduction 507
            negative regulation of I-kappaB kinase/NF-kappaB signaling + 45
            negative regulation of MAPK cascade + 168
            negative regulation of NIK/NF-kappaB signaling 23
            negative regulation of TOR signaling + 43
            negative regulation of cAMP-mediated signaling + 29
            negative regulation of cGMP-mediated signaling 6
            negative regulation of calcium-mediated signaling + 32
            negative regulation of hippo signaling 10
            negative regulation of intrinsic apoptotic signaling pathway + 98
            negative regulation of mitotic spindle assembly checkpoint signaling 0
            negative regulation of nitric oxide mediated signal transduction 3
            negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
            negative regulation of phosphatidylinositol 3-kinase signaling 16
            negative regulation of phosphorelay signal transduction system + 0
            negative regulation of protein kinase B signaling 42
            negative regulation of protein kinase C signaling 5
            negative regulation of protein kinase D signaling 0
            negative regulation of signal transduction by p53 class mediator + 33
            negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint 0
            negative regulation of small GTPase mediated signal transduction + 56
            negative regulation of stress-activated protein kinase signaling cascade + 45
            negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 12490
    biological regulation 9100
      regulation of biological process 8627
        regulation of cellular process 8158
          signal transduction 3789
            regulation of signal transduction 2587
              negative regulation of signal transduction 1149
                negative regulation of intracellular signal transduction 507
                  negative regulation of I-kappaB kinase/NF-kappaB signaling + 45
                  negative regulation of MAPK cascade + 168
                  negative regulation of NIK/NF-kappaB signaling 23
                  negative regulation of TOR signaling + 43
                  negative regulation of cAMP-mediated signaling + 29
                  negative regulation of cGMP-mediated signaling 6
                  negative regulation of calcium-mediated signaling + 32
                  negative regulation of hippo signaling 10
                  negative regulation of intrinsic apoptotic signaling pathway + 98
                  negative regulation of mitotic spindle assembly checkpoint signaling 0
                  negative regulation of nitric oxide mediated signal transduction 3
                  negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
                  negative regulation of phosphatidylinositol 3-kinase signaling 16
                  negative regulation of phosphorelay signal transduction system + 0
                  negative regulation of protein kinase B signaling 42
                  negative regulation of protein kinase C signaling 5
                  negative regulation of protein kinase D signaling 0
                  negative regulation of signal transduction by p53 class mediator + 33
                  negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint 0
                  negative regulation of small GTPase mediated signal transduction + 56
                  negative regulation of stress-activated protein kinase signaling cascade + 45
                  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.