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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intracellular signal transduction
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Accession:GO:1902532 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
Synonyms:exact_synonym: down regulation of intracellular signal transduction;   down regulation of intracellular signaling chain;   downregulation of intracellular signal transduction;   downregulation of intracellular signaling chain;   negative regulation of intracellular protein kinase cascade;   negative regulation of intracellular signaling cascade;   negative regulation of intracellular signaling chain
 narrow_synonym: down regulation of intracellular signal transduction pathway;   downregulation of intracellular signal transduction pathway;   downregulation of intracellular signaling cascade;   downregulation of signal transmission via intracellular cascade;   inhibition of intracellular signal transduction;   inhibition of intracellular signal transduction pathway;   inhibition of intracellular signaling cascade;   inhibition of intracellular signaling chain;   inhibition of signal transmission via intracellular cascade;   negative regulation of intracellular signal transduction pathway;   negative regulation of signal transmission via intracellular cascade
 related_synonym: down regulation of intracellular signaling pathway;   down regulation of signal transduction via intracellular signaling cascade;   down-regulation of intracellular signaling cascade;   down-regulation of signal transmission via intracellular cascade;   downregulation of intracellular signaling pathway;   downregulation of signal transduction via intracellular signaling cascade;   inhibition of intracellular signaling pathway;   inhibition of signal transduction via intracellular signaling cascade;   negative regulation of intracellular signaling pathway;   negative regulation of signal transduction via intracellular signaling cascade
 alt_id: GO:0010741


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negative regulation of intracellular signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDIT4 DNA damage inducible transcript 4 JBrowse link 4 22,916,718 22,918,893 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 29 7,367,617 7,448,862 RGD:9068941
inactivation of MAPK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:13508589
G DUSP1 dual specificity phosphatase 1 JBrowse link 4 39,588,833 39,591,065 RGD:13508589
G DUSP10 dual specificity phosphatase 10 JBrowse link 38 16,196,354 16,233,640 RGD:13508589
G DUSP14 dual specificity phosphatase 14 JBrowse link 9 37,253,305 37,277,320 RGD:13508589
G DUSP16 dual specificity phosphatase 16 JBrowse link 27 33,728,209 33,831,258 RGD:13508589
G DUSP19 dual specificity phosphatase 19 JBrowse link 36 26,095,436 26,111,700 RGD:9068941
G DUSP2 dual specificity phosphatase 2 JBrowse link 17 34,586,635 34,589,076 RGD:13508589
G DUSP21 dual specificity phosphatase 21 JBrowse link X 38,721,877 38,722,808 RGD:13508589
G DUSP3 dual specificity phosphatase 3 JBrowse link 9 19,518,302 19,531,000 RGD:13508589
G DUSP4 dual specificity phosphatase 4 RGD:13508589
G DUSP5 dual specificity phosphatase 5 JBrowse link 28 21,829,891 21,844,590 RGD:13508589
G DUSP6 dual specificity phosphatase 6 JBrowse link 15 30,322,472 30,327,221 RGD:13508589
G DUSP7 dual specificity phosphatase 7 JBrowse link 20 37,676,077 37,682,003 RGD:13508589
G DUSP8 dual specificity phosphatase 8 JBrowse link 18 45,791,878 45,809,996 RGD:13508589
G DUSP9 dual specificity phosphatase 9 JBrowse link X 121,460,116 121,472,605 RGD:13508589
G LAX1 lymphocyte transmembrane adaptor 1 JBrowse link 38 429,062 438,069 RGD:13508589
G PRKCA protein kinase C alpha JBrowse link 9 13,638,106 13,879,571 RGD:9068941
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 1 114,619,478 114,626,082 RGD:13508589
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 30 5,594,327 5,716,082 RGD:13508589
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 10 64,764,275 64,815,937 RGD:13508589
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 1 114,604,265 114,614,764 RGD:13508589
inactivation of MAPKK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EPHB2 EPH receptor B2 JBrowse link 2 76,427,112 76,551,494 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARRDC3 arrestin domain containing 3 JBrowse link 3 17,691,631 17,705,507 RGD:13508589
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 38 321,246 420,262 RGD:13508589
G GNAI2 G protein subunit alpha i2 JBrowse link 20 39,075,085 39,094,697 RGD:9068941
G PDE4B phosphodiesterase 4B JBrowse link 5 44,063,145 44,606,070 RGD:9068941
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLP1 amyloid beta precursor like protein 1 JBrowse link 1 116,774,392 116,783,101 RGD:9068941
G GRK2 G protein-coupled receptor kinase 2 JBrowse link 18 50,148,566 50,167,422 RGD:9068941
G GRK5 G protein-coupled receptor kinase 5 JBrowse link 28 29,424,350 29,636,552 RGD:9068941
G MRAP melanocortin 2 receptor accessory protein JBrowse link 31 27,058,469 27,085,704 RGD:9068941
G MRAP2 melanocortin 2 receptor accessory protein 2 JBrowse link 12 44,323,932 44,373,170 RGD:13508589
G OPRL1 opioid related nociceptin receptor 1 JBrowse link 24 47,530,039 47,537,477 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 1 43,972,915 44,037,477 RGD:9068941
G PTGER3 prostaglandin E receptor 3 JBrowse link 6 74,932,789 74,986,573 RGD:9068941
negative regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GIT1 GIT ArfGAP 1 JBrowse link 9 43,676,707 43,686,566 RGD:9068941
negative regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTN3 actinin alpha 3 JBrowse link 18 50,787,353 50,801,036 RGD:13508589
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 38 321,246 420,262 RGD:13508589
G C3H15orf40 chromosome 3 C15orf40 homolog JBrowse link 3 54,788,092 54,793,197 RGD:13508589
G CHP1 calcineurin like EF-hand protein 1 JBrowse link 30 8,304,939 8,352,833 RGD:13508589
G CMYA5 cardiomyopathy associated 5 JBrowse link 3 27,181,502 27,271,718 RGD:9068941
G DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 JBrowse link 10 9,982,245 9,994,327 RGD:13508589
G FHL2 four and a half LIM domains 2 JBrowse link 10 37,997,912 38,065,633 RGD:13508589
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:13508589
G HOMER3 homer scaffold protein 3 JBrowse link 20 44,179,145 44,186,814 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 5 40,831,949 40,836,990 RGD:13508589
G MTOR mechanistic target of rapamycin kinase JBrowse link 2 84,818,893 84,939,283 RGD:13508589
G MYOZ1 myozenin 1 JBrowse link 4 24,158,532 24,165,416 RGD:13508589
G MYOZ2 myozenin 2 JBrowse link 32 38,088,505 38,132,265 RGD:13508589
G PRNP prion protein JBrowse link 24 16,845,224 16,862,319 RGD:9068941
G RCAN1 regulator of calcineurin 1 JBrowse link 31 29,908,046 30,002,412 RGD:9068941
G TBC1D10C TBC1 domain family member 10C JBrowse link 18 50,055,376 50,062,166 RGD:13508589
negative regulation of calcium-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD22 CD22 molecule JBrowse link 1 117,261,730 117,285,775 RGD:9068941
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 JBrowse link 20 12,746,171 13,065,256 RGD:13508589
G LOC484343 sialic acid-binding Ig-like lectin 10 JBrowse link 1 105,532,181 105,575,278 RGD:9068941
G SLA2 Src like adaptor 2 JBrowse link 24 25,396,187 25,426,789 RGD:13508589
negative regulation of CAMKK-AMPK signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGLN1 egl-9 family hypoxia inducible factor 1 JBrowse link 4 8,053,486 8,110,791 RGD:9068941
negative regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLNR apelin receptor JBrowse link 18 38,878,621 38,882,280 RGD:13508589
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme JBrowse link 20 57,960,506 57,967,388 RGD:13508589
G CRHR2 corticotropin releasing hormone receptor 2 JBrowse link 14 43,366,849 43,414,398 RGD:9068941
G CRTC3 CREB regulated transcription coactivator 3 JBrowse link 3 53,564,244 53,669,778 RGD:13508589
G LPAR1 lysophosphatidic acid receptor 1 JBrowse link 11 65,690,806 65,822,166 RGD:9068941
G MGRN1 mahogunin ring finger 1 JBrowse link 6 36,716,071 36,775,893 RGD:13508589
G NPY2R neuropeptide Y receptor Y2 JBrowse link 15 52,790,136 52,797,785 RGD:9068941
G NUCB2 nucleobindin 2 JBrowse link 21 39,868,756 39,918,724 RGD:9068941
G OPRL1 opioid related nociceptin receptor 1 JBrowse link 24 47,530,039 47,537,477 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 1 43,972,915 44,037,477 RGD:9068941
G PDE10A phosphodiesterase 10A JBrowse link 1 53,457,781 54,049,735 RGD:9068941
G PDE11A phosphodiesterase 11A JBrowse link 36 21,347,171 21,701,976 RGD:13508589
G PDE2A phosphodiesterase 2A JBrowse link 21 25,542,030 25,635,661 RGD:13508589
G PDE3A phosphodiesterase 3A JBrowse link 27 26,555,558 26,878,624 RGD:13508589
G PDE3B phosphodiesterase 3B JBrowse link 21 37,364,940 37,532,152 RGD:13508589
G PDE4D phosphodiesterase 4D JBrowse link 2 45,843,767 47,245,263 RGD:13508589
G RGS2 regulator of G protein signaling 2 JBrowse link 38 6,200,237 6,203,491 RGD:13508589
G RNF157 ring finger protein 157 JBrowse link 9 4,416,423 4,511,793 RGD:13508589
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 11 22,523,671 22,541,473 RGD:13508589
negative regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTNR1B melatonin receptor 1B JBrowse link 21 7,639,532 7,643,534 RGD:9068941
G PDE10A phosphodiesterase 10A JBrowse link 1 53,457,781 54,049,735 RGD:13508589
G PDE11A phosphodiesterase 11A JBrowse link 36 21,347,171 21,701,976 RGD:13508589
G PDE2A phosphodiesterase 2A JBrowse link 21 25,542,030 25,635,661 RGD:13508589
G PDZD3 PDZ domain containing 3 JBrowse link 5 14,687,868 14,692,474 RGD:13508589
G THBS1 thrombospondin 1 JBrowse link 30 6,770,212 6,786,875 RGD:13508589
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD44 CD44 molecule JBrowse link 18 32,735,493 32,826,483 RGD:9068941
G CD74 CD74 molecule JBrowse link 4 58,689,745 58,698,421 RGD:13508589
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link 31 32,564,970 32,655,232 RGD:13508589
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 7 5,816,839 5,826,194 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 2 76,313,742 76,375,716 RGD:9068941
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 36 5,481,449 5,533,139 RGD:13508589
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 81,625,288 81,632,175 RGD:13508589
G PTTG1IP PTTG1 interacting protein JBrowse link 31 38,494,608 38,513,997 RGD:9068941
G SENP2 SUMO specific peptidase 2 JBrowse link 34 18,325,373 18,357,152 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G SNAI1 snail family transcriptional repressor 1 JBrowse link 24 36,498,343 36,503,623 RGD:13508589
G SNAI2 snail family transcriptional repressor 2 JBrowse link 29 1,154,132 1,156,653 RGD:13508589
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCBP4 poly(rC) binding protein 4 JBrowse link 20 37,748,854 37,759,072 RGD:9068941
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2L1 BCL2 like 1 JBrowse link 24 21,145,214 21,209,425 RGD:13508589
G CREB3 cAMP responsive element binding protein 3 JBrowse link 11 52,260,340 52,265,085 RGD:13508589
G CREB3L1 cAMP responsive element binding protein 3 like 1 JBrowse link 18 43,138,779 43,173,535 RGD:9068941
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 JBrowse link 13 37,512,129 37,514,303 RGD:13508589
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 2 59,388,492 59,400,028 RGD:13508589
G HSP70 heat shock protein 70 JBrowse link 12 1,285,282 1,287,670 RGD:9068941
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 122,232,052 122,253,499 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:13508589
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 23 52,068,123 52,154,410 RGD:13508589
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G PDX1 pancreatic and duodenal homeobox 1 JBrowse link 25 11,741,863 11,746,885 RGD:13508589
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 24 36,936,469 37,010,929 RGD:13508589
G SELENOS selenoprotein S JBrowse link 3 39,796,711 39,805,654 RGD:13508589
G SYVN1 synoviolin 1 JBrowse link 18 52,061,284 52,068,672 RGD:9068941
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 27 4,921,606 4,944,830 RGD:13508589
G TXNDC12 thioredoxin domain containing 12 JBrowse link 15 9,261,493 9,292,097 RGD:13508589
G WFS1 wolframin ER transmembrane glycoprotein JBrowse link 13 38,451,722 38,466,481 RGD:13508589
G XBP1 X-box binding protein 1 JBrowse link 26 22,162,675 22,168,149 RGD:9068941
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HYOU1 hypoxia up-regulated 1 JBrowse link 5 14,795,750 14,808,203 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
negative regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 53,118,462 53,262,092 RGD:13508589
G ACE2 angiotensin I converting enzyme 2 JBrowse link X 11,798,839 11,839,591 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:9068941
G ARRB1 arrestin beta 1 JBrowse link 21 23,261,020 23,304,448 RGD:9068941
G ATF3 activating transcription factor 3 JBrowse link 7 10,784,445 10,795,285 RGD:13508589
G C1QL4 complement C1q like 4 JBrowse link 27 5,278,347 5,281,827 RGD:13508589
G C23H3orf33 chromosome 23 C3orf33 homolog JBrowse link 23 49,485,250 49,504,331 RGD:13508589
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:9068941
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit JBrowse link 21 26,216,862 26,233,226 RGD:9068941
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 3 36,852,082 37,164,930 RGD:9068941
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit JBrowse link 3 72,190,431 72,204,092 RGD:9068941
G CNKSR3 CNKSR family member 3 JBrowse link 1 44,280,132 44,361,138 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 9 43,372,507 43,378,561 RGD:9068941
G CSK C-terminal Src kinase JBrowse link 30 37,851,269 37,870,382 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 60,725,887 60,918,242 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 33 30,016,323 30,253,180 RGD:9068941
G DMD dystrophin JBrowse link X 26,290,903 28,444,635 RGD:13508589
G DUSP1 dual specificity phosphatase 1 JBrowse link 4 39,588,833 39,591,065 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 38 16,196,354 16,233,640 RGD:13508589
G DUSP26 dual specificity phosphatase 26 JBrowse link 16 31,115,317 31,122,767 RGD:13508589
G DUSP3 dual specificity phosphatase 3 JBrowse link 9 19,518,302 19,531,000 RGD:13508589
G DUSP4 dual specificity phosphatase 4 RGD:13508589
G DUSP6 dual specificity phosphatase 6 JBrowse link 15 30,322,472 30,327,221 RGD:13508589
G DUSP9 dual specificity phosphatase 9 JBrowse link X 121,460,116 121,472,605 RGD:13508589
G EIF3A eukaryotic translation initiation factor 3 subunit A JBrowse link 28 29,290,668 29,326,851 RGD:9068941
G EMILIN1 elastin microfibril interfacer 1 JBrowse link 17 21,071,502 21,078,888 RGD:13508589
G EPHB2 EPH receptor B2 JBrowse link 2 76,427,112 76,551,494 RGD:9068941
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 5 61,621,964 61,636,152 RGD:9068941
G EZR ezrin JBrowse link 1 48,160,206 48,210,036 RGD:13508589
G FBLN1 fibulin 1 JBrowse link 10 20,498,097 20,564,776 RGD:9068941
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G GBP1 guanylate binding protein 1 JBrowse link 6 59,378,069 59,393,388 RGD:13508589
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 6 15,792,072 15,796,922 RGD:13508589
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 15 41,203,320 41,275,964 RGD:9068941
G ITGB1BP1 integrin subunit beta 1 binding protein 1 JBrowse link 17 6,524,602 6,537,321 RGD:13508589
G KLF4 Kruppel like factor 4 JBrowse link 11 62,881,840 62,886,676 RGD:9068941
G LIF LIF interleukin 6 family cytokine JBrowse link 26 23,400,226 23,418,538 RGD:13508589
G LMO3 LIM domain only 3 JBrowse link 27 30,150,311 30,208,286 RGD:9068941
G LOC100855640 butyrophilin subfamily 2 member A2 JBrowse link 35 24,251,221 24,265,040 RGD:13508589
G LOC100855742 NACHT, LRR and PYD domains-containing protein 12-like JBrowse link 1 103,571,756 103,605,692 RGD:9068941
G LOC100856420 ankyrin repeat domain-containing protein 26-like JBrowse link 2 6,703,880 6,765,327 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 29 7,367,617 7,448,862 RGD:9068941
G NDRG2 NDRG family member 2 JBrowse link 15 18,106,651 18,115,026 RGD:13508589
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 18 25,433,481 25,440,703 RGD:13508589
G PHB prohibitin JBrowse link 9 25,525,711 25,536,722 RGD:13508589
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 1 14,027,741 14,234,229 RGD:9068941
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 20 51,156,887 51,168,131 RGD:13508589
G PSCA prostate stem cell antigen JBrowse link 13 36,773,434 36,776,740 RGD:13508589
G PTEN phosphatase and tensin homolog JBrowse link 26 37,853,148 37,913,176 RGD:13508589
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 24 36,936,469 37,010,929 RGD:13508589
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 7 78,160,564 78,252,382 RGD:13508589
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 7 4,155,876 4,282,151 RGD:9068941
G PTPRR protein tyrosine phosphatase receptor type R JBrowse link 10 12,385,121 12,618,438 RGD:13508589
G RANBP9 RAN binding protein 9 JBrowse link 35 13,063,689 13,157,228 RGD:13508589
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 52,429,204 52,566,775 RGD:9068941
G RGS14 regulator of G protein signaling 14 JBrowse link 4 35,984,970 35,999,386 RGD:9068941
G RPS6KA6 ribosomal protein S6 kinase A6 JBrowse link X 64,915,871 65,111,095 RGD:9068941
G SEMA6A semaphorin 6A JBrowse link 11 6,117,063 6,245,443 RGD:9068941
G SIRPA signal regulatory protein alpha JBrowse link 24 19,094,930 19,136,655 RGD:9068941
G SIRT3 sirtuin 3 JBrowse link 18 25,369,183 25,388,126 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 9 5,661,792 5,679,783 RGD:13508589
G SMAD4 SMAD family member 4 JBrowse link 1 23,875,989 23,930,027 RGD:13508589
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 30 5,594,327 5,716,082 RGD:9068941
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 10 64,764,275 64,815,937 RGD:9068941
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 1 114,604,265 114,614,764 RGD:9068941
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 19 16,969,869 16,976,573 RGD:13508589
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 22 33,366,139 33,371,102 RGD:13508589
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 2 37,199,890 37,213,710 RGD:13508589
G SYNJ2BP synaptojanin 2 binding protein JBrowse link 8 44,044,526 44,079,002 RGD:13508589
G TBC1D10C TBC1 domain family member 10C JBrowse link 18 50,055,376 50,062,166 RGD:13508589
G TIMP3 TIMP metallopeptidase inhibitor 3 JBrowse link 10 30,627,154 30,681,520 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 11 71,356,390 71,367,166 RGD:13508589
G TNIP1 TNFAIP3 interacting protein 1 JBrowse link 4 58,150,734 58,200,158 RGD:13508589
G VRK3 VRK serine/threonine kinase 3 JBrowse link 1 106,564,151 106,601,321 RGD:13508589
G WNK2 WNK lysine deficient protein kinase 2 JBrowse link 1 98,433,897 98,533,427 RGD:9068941
G XBP1 X-box binding protein 1 JBrowse link 26 22,162,675 22,168,149 RGD:9068941
negative regulation of ERK5 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 5 40,831,949 40,836,990 RGD:9068941
negative regulation of hippo signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AJUBA ajuba LIM protein JBrowse link 8 3,272,408 3,302,179 RGD:13508589
G DLG5 discs large MAGUK scaffold protein 5 JBrowse link 4 27,687,223 27,780,007 RGD:9068941
G LIMD1 LIM domains containing 1 JBrowse link 20 42,797,316 42,867,292 RGD:13508589
G MAP2K3 mitogen-activated protein kinase kinase 3 JBrowse link 5 42,732,751 42,762,420 RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 12 5,145,647 5,221,558 RGD:9068941
G MARK3 microtubule affinity regulating kinase 3 JBrowse link 8 71,148,263 71,269,717 RGD:9068941
G VGLL4 vestigial like family member 4 JBrowse link 20 6,751,951 6,915,650 RGD:13508589
G WTIP WT1 interacting protein JBrowse link 1 117,802,933 117,835,770 RGD:9068941
G WWC1 WW and C2 domain containing 1 JBrowse link 4 43,279,788 43,431,503 RGD:13508589
G WWC2 WW and C2 domain containing 2 JBrowse link 16 47,014,151 47,185,456 RGD:13508589
G WWC3 WWC family member 3 JBrowse link X 6,716,428 6,836,381 RGD:13508589
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:9068941
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENO1 enolase 1 JBrowse link 5 62,300,805 62,314,508 RGD:9068941
G HYOU1 hypoxia up-regulated 1 JBrowse link 5 14,795,750 14,808,203 RGD:13508589
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 30 30,683,192 30,760,479 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:9068941
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 27 4,921,606 4,944,830 RGD:13508589
negative regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 53,118,462 53,262,092 RGD:13508589
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:9068941
G ASH1L ASH1 like histone lysine methyltransferase JBrowse link 7 42,046,262 42,227,737 RGD:13508589
G CACTIN cactin, spliceosome C complex subunit JBrowse link 20 55,803,494 55,817,467 RGD:13508589
G CARD8 caspase recruitment domain family, member 8 JBrowse link 1 107,994,215 108,025,875 RGD:9068941
G CASP8 caspase 8 JBrowse link 37 10,362,071 10,402,108 RGD:13508589
G CCDC22 coiled-coil domain containing 22 JBrowse link X 42,329,320 42,343,270 RGD:13508589
G DAB2IP DAB2 interacting protein JBrowse link 9 60,725,887 60,918,242 RGD:9068941
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 6 36,921,941 36,967,718 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 1 42,081,952 42,368,544 RGD:13508589
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G HDAC1 histone deacetylase 1 JBrowse link 2 68,901,339 68,936,473 RGD:13508589
G IL1RL1 interleukin 1 receptor like 1 JBrowse link 10 40,658,191 40,732,097 RGD:9068941
G LOC100855742 NACHT, LRR and PYD domains-containing protein 12-like JBrowse link 1 103,571,756 103,605,692 RGD:13508589
G LOC102154748 E3 ubiquitin-protein ligase TRIM39 JBrowse link 12 317,149 330,907 RGD:9068941
G LOC102157101 NACHT, LRR and PYD domains-containing protein 3 JBrowse link X 81,470,922 81,513,201 RGD:13508589
G MAPKBP1 mitogen-activated protein kinase binding protein 1 JBrowse link 30 8,807,584 8,857,693 RGD:13508589
G NFKBID NFKB inhibitor delta JBrowse link 1 116,763,371 116,770,683 RGD:13508589
G NLRC3 NLR family CARD domain containing 3 JBrowse link 6 37,668,654 37,707,387 RGD:13508589
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 18 25,433,481 25,440,703 RGD:13508589
G NLRX1 NLR family member X1 JBrowse link 5 14,692,621 14,705,214 RGD:13508589
G NR1D1 nuclear receptor subfamily 1 group D member 1 JBrowse link 9 22,461,556 22,469,243 RGD:13508589
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 15 39,497,313 39,608,120 RGD:13508589
G OLFM4 olfactomedin 4 JBrowse link 22 10,053,494 10,075,759 RGD:9068941
G OPTN optineurin JBrowse link 2 23,356,471 23,390,569 RGD:13508589
G OTUD7A OTU deubiquitinase 7A JBrowse link 3 37,348,167 37,548,357 RGD:13508589
G OTUD7B OTU deubiquitinase 7B JBrowse link 17 59,225,640 59,280,875 RGD:13508589
G PER1 period circadian regulator 1 JBrowse link 5 32,957,517 32,972,368 RGD:9068941
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A JBrowse link 8 35,336,055 35,384,249 RGD:13508589
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B JBrowse link 10 46,590,110 46,680,792 RGD:13508589
G PPM1N protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) JBrowse link 1 110,067,163 110,071,274 RGD:13508589
G PYCARD PYD and CARD domain containing JBrowse link 6 17,049,352 17,051,348 RGD:13508589
G RHOA ras homolog family member A JBrowse link 20 39,824,552 39,888,089 RGD:9068941
G RHOH ras homolog family member H JBrowse link 3 72,272,446 72,277,015 RGD:13508589
G RIOK3 RIO kinase 3 JBrowse link 7 64,835,810 64,860,464 RGD:13508589
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 35 3,367,796 3,407,631 RGD:13508589
G RORA RAR related orphan receptor A JBrowse link 30 25,315,974 26,026,708 RGD:13508589
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G STAT1 signal transducer and activator of transcription 1 JBrowse link 37 1,513,438 1,549,837 RGD:9068941
G TANK TRAF family member associated NFKB activator JBrowse link 36 6,732,507 6,826,762 RGD:13508589
G TLE1 TLE family member 1, transcriptional corepressor JBrowse link 1 77,554,718 77,639,608 RGD:13508589
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 1 30,247,432 30,262,992 RGD:13508589
G TNIP1 TNFAIP3 interacting protein 1 JBrowse link 4 58,150,734 58,200,158 RGD:13508589
G TNIP3 TNFAIP3 interacting protein 3 JBrowse link 19 18,857,719 18,960,760 RGD:13508589
G TRIM59 tripartite motif containing 59 JBrowse link 34 26,495,628 26,509,445 RGD:13508589
G TYROBP transmembrane immune signaling adaptor TYROBP JBrowse link 1 116,757,271 116,760,453 RGD:13508589
G USP10 ubiquitin specific peptidase 10 JBrowse link 5 67,736,215 67,774,756 RGD:13508589
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 15 4,972,369 4,984,218 RGD:13508589
G ZMYND11 zinc finger MYND-type containing 11 JBrowse link 2 34,492,283 34,614,152 RGD:9068941
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRPA signal regulatory protein alpha JBrowse link 24 19,094,930 19,136,655 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:13508589
G BCL2 BCL2 apoptosis regulator JBrowse link 1 13,733,849 13,900,653 RGD:13508589
G BCL2L1 BCL2 like 1 JBrowse link 24 21,145,214 21,209,425 RGD:13508589
G BCL2L10 BCL2 like 10 JBrowse link 30 17,824,030 17,828,115 RGD:9068941
G BCL2L2 BCL2 like 2 JBrowse link 8 3,569,335 3,573,922 RGD:13508589
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 35,759,367 35,789,759 RGD:9068941
G FIGNL1 fidgetin like 1 JBrowse link 18 1,788,063 1,792,900 RGD:13508589
G G2E3 G2/M-phase specific E3 ubiquitin protein ligase JBrowse link 8 9,914,276 9,968,798 RGD:9068941
G GCG glucagon JBrowse link 36 7,544,637 7,554,171 RGD:9068941
G HDAC1 histone deacetylase 1 JBrowse link 2 68,901,339 68,936,473 RGD:13508589
G HDAC2 histone deacetylase 2 JBrowse link 12 70,053,822 70,083,491 RGD:9068941
G HELLS helicase, lymphoid specific JBrowse link 28 8,660,866 8,705,570 RGD:13508589
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 2 59,388,492 59,400,028 RGD:9068941
G IVNS1ABP influenza virus NS1A binding protein JBrowse link 7 18,430,970 18,444,573 RGD:13508589
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 18 43,517,186 43,522,603 RGD:9068941
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 17 59,759,605 59,763,111 RGD:13508589
G MMP9 matrix metallopeptidase 9 JBrowse link 24 33,274,260 33,281,116 RGD:13508589
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 20 43,721,568 43,730,607 RGD:13508589
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 JBrowse link 18 42,069,402 42,075,843 RGD:9068941
G NOC2L NOC2 like nucleolar associated transcriptional repressor JBrowse link 5 56,172,399 56,185,993 RGD:13508589
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 23 52,068,123 52,154,410 RGD:9068941
G PARL presenilin associated rhomboid like JBrowse link 34 16,790,049 16,837,557 RGD:13508589
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:9068941
G PLAUR plasminogen activator, urokinase receptor JBrowse link 1 111,476,804 111,490,876 RGD:13508589
G PPIF peptidylprolyl isomerase F JBrowse link 4 29,074,806 29,080,487 RGD:9068941
G RTKN2 rhotekin 2 JBrowse link 4 14,165,569 14,245,088 RGD:13508589
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 24 25,982,499 26,019,748 RGD:13508589
G URI1 URI1 prefoldin like chaperone JBrowse link 1 121,528,706 121,612,200 RGD:9068941
G VDAC2 voltage dependent anion channel 2 JBrowse link 4 25,449,926 25,462,147 RGD:13508589
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMC10 armadillo repeat containing 10 JBrowse link 18 16,994,583 17,020,417 RGD:9068941
G CEP63 centrosomal protein 63 JBrowse link 23 31,249,517 31,303,145 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G MDM4 MDM4 regulator of p53 JBrowse link 38 1,055,978 1,122,348 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
G PTTG1IP PTTG1 interacting protein JBrowse link 31 38,494,608 38,513,997 RGD:9068941
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 13 3,774,725 3,838,576 RGD:13508589
G RRN3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 6 28,478,770 28,507,722 RGD:13508589
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 6 61,439,414 61,471,414 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACKR3 atypical chemokine receptor 3 JBrowse link 25 47,327,921 47,339,632 RGD:13508589
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 24 21,145,214 21,209,425 RGD:13508589
G BID BH3 interacting domain death agonist JBrowse link 27 45,344,304 45,355,735 RGD:9068941
G CCAR2 cell cycle and apoptosis regulator 2 JBrowse link 25 34,660,026 34,674,129 RGD:13508589
G CDKN2D cyclin dependent kinase inhibitor 2D JBrowse link 20 50,607,382 50,609,929 RGD:9068941
G CLU clusterin JBrowse link 25 29,982,811 29,999,565 RGD:13508589
G CXCL12 C-X-C motif chemokine ligand 12 JBrowse link 28 2,895,916 2,903,543 RGD:9068941
G DDIAS DNA damage induced apoptosis suppressor JBrowse link 21 16,192,071 16,219,704 RGD:13508589
G SFRP2 secreted frizzled related protein 2 JBrowse link 15 51,541,197 51,548,765 RGD:13508589
G SNAI1 snail family transcriptional repressor 1 JBrowse link 24 36,498,343 36,503,623 RGD:13508589
G SNAI2 snail family transcriptional repressor 2 JBrowse link 29 1,154,132 1,156,653 RGD:13508589
G TMEM161A transmembrane protein 161A JBrowse link 20 44,021,722 44,037,985 RGD:9068941
G TPT1 tumor protein, translationally-controlled 1 JBrowse link 22 5,711,076 5,715,254 RGD:9068941
G TRIM32 tripartite motif containing 32 JBrowse link 11 70,453,130 70,465,030 RGD:13508589
G USP47 ubiquitin specific peptidase 47 JBrowse link 21 34,917,664 35,027,969 RGD:13508589
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:13508589
G BCL2L12 BCL2 like 12 JBrowse link 1 106,865,346 106,873,329 RGD:9068941
G CD44 CD44 molecule JBrowse link 18 32,735,493 32,826,483 RGD:9068941
G CD74 CD74 molecule JBrowse link 4 58,689,745 58,698,421 RGD:13508589
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 30 10,514,633 10,517,963 RGD:13508589
G KDM1A lysine demethylase 1A JBrowse link 2 76,313,742 76,375,716 RGD:9068941
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 36 5,481,449 5,533,139 RGD:13508589
G MUC1 mucin 1, cell surface associated JBrowse link 7 42,338,939 42,344,690 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 26 16,349,513 16,352,805 RGD:9068941
G ZNF385A zinc finger protein 385A JBrowse link 27 928,250 948,275 RGD:13508589
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 25 8,972,942 8,998,404 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:9068941
G TRAP1 TNF receptor associated protein 1 JBrowse link 6 37,544,929 37,596,789 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 7 41,835,322 41,850,488 RGD:13508589
G BDKRB2 bradykinin receptor B2 JBrowse link 8 64,974,588 65,005,682 RGD:9068941
G EPO erythropoietin JBrowse link 6 8,994,211 8,995,954 RGD:13508589
G PTGER2 prostaglandin E receptor 2 JBrowse link 8 28,523,318 28,536,936 RGD:13508589
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 7 19,668,079 19,674,903 RGD:13508589
G YBX3 Y-box binding protein 3 JBrowse link 27 35,043,756 35,066,230 RGD:13508589
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BDKRB2 bradykinin receptor B2 JBrowse link 8 64,974,588 65,005,682 RGD:13508589
negative regulation of JNK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIDA axin interactor, dorsalization associated JBrowse link 38 16,938,279 16,971,200 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:9068941
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 1 111,902,429 111,919,191 RGD:9068941
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 2 64,561,684 64,628,829 RGD:9068941
G DACT1 dishevelled binding antagonist of beta catenin 1 JBrowse link 8 33,950,016 33,959,671 RGD:13508589
G DUSP10 dual specificity phosphatase 10 JBrowse link 38 16,196,354 16,233,640 RGD:13508589
G DUSP19 dual specificity phosphatase 19 JBrowse link 36 26,095,436 26,111,700 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 9 19,518,302 19,531,000 RGD:13508589
G F2RL1 F2R like trypsin receptor 1 JBrowse link 3 29,801,119 29,810,006 RGD:13508589
G FKTN fukutin JBrowse link 11 61,394,002 61,462,056 RGD:9068941
G GPS2 G protein pathway suppressor 2 JBrowse link 5 32,273,169 32,275,915 RGD:13508589
G HDAC3 histone deacetylase 3 JBrowse link 2 36,583,283 36,598,121 RGD:13508589
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 24 23,476,619 23,630,574 RGD:13508589
G KLHL31 kelch like family member 31 JBrowse link 12 21,153,843 21,201,345 RGD:13508589
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 18 43,517,186 43,522,603 RGD:9068941
G MARVELD3 MARVEL domain containing 3 JBrowse link 5 77,412,353 77,421,032 RGD:13508589
G MECOM MDS1 and EVI1 complex locus JBrowse link 34 33,747,495 34,299,389 RGD:9068941
G MEN1 menin 1 JBrowse link 18 52,346,747 52,352,884 RGD:13508589
G NCOR1 nuclear receptor corepressor 1 JBrowse link 5 39,687,530 39,837,003 RGD:9068941
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 JBrowse link 9 46,648,057 46,731,259 RGD:13508589
G PER1 period circadian regulator 1 JBrowse link 5 32,957,517 32,972,368 RGD:9068941
G SFRP4 secreted frizzled related protein 4 JBrowse link 18 12,018,049 12,028,123 RGD:9068941
G SH3RF2 SH3 domain containing ring finger 2 JBrowse link 2 40,380,313 40,514,211 RGD:9068941
G SIRPA signal regulatory protein alpha JBrowse link 24 19,094,930 19,136,655 RGD:9068941
G TAOK3 TAO kinase 3 JBrowse link 26 14,534,083 14,712,779 RGD:13508589
G ZMYND11 zinc finger MYND-type containing 11 JBrowse link 2 34,492,283 34,614,152 RGD:9068941
negative regulation of JUN kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIDA axin interactor, dorsalization associated JBrowse link 38 16,938,279 16,971,200 RGD:13508589
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 11 50,156,089 50,168,379 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 38 16,196,354 16,233,640 RGD:13508589
G DUSP19 dual specificity phosphatase 19 JBrowse link 36 26,095,436 26,111,700 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G HIPK3 homeodomain interacting protein kinase 3 JBrowse link 18 34,305,208 34,397,593 RGD:13508589
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 18 43,517,186 43,522,603 RGD:9068941
G NPPA natriuretic peptide A JBrowse link 2 84,406,317 84,408,115 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 17 51,623,628 51,683,039 RGD:9068941
G SFRP1 secreted frizzled related protein 1 JBrowse link 16 24,262,451 24,306,162 RGD:9068941
G SFRP2 secreted frizzled related protein 2 JBrowse link 15 51,541,197 51,548,765 RGD:13508589
G SFRP5 secreted frizzled related protein 5 JBrowse link 28 10,994,180 10,999,552 RGD:9068941
G TP73 tumor protein p73 JBrowse link 5 58,194,385 58,241,159 RGD:9068941
negative regulation of MAP kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:9068941
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:13508589
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:9068941
G BMP4 bone morphogenetic protein 4 JBrowse link 8 29,997,563 30,254,307 RGD:13508589
G BMP7 bone morphogenetic protein 7 JBrowse link 24 42,203,183 42,294,105 RGD:13508589
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:9068941
G CAV3 caveolin 3 JBrowse link 20 9,384,901 9,398,055 RGD:13508589
G CBLC Cbl proto-oncogene C JBrowse link 1 110,590,548 110,606,775 RGD:13508589
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 JBrowse link 9 24,276,660 24,286,273 RGD:13508589
G DAB2IP DAB2 interacting protein JBrowse link 9 60,725,887 60,918,242 RGD:9068941
G DEFB114 defensin beta 114 JBrowse link 12 17,771,204 17,781,535 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 4 39,588,833 39,591,065 RGD:9068941
G DUSP7 dual specificity phosphatase 7 JBrowse link 20 37,676,077 37,682,003 RGD:9068941
G FEM1A fem-1 homolog A JBrowse link 20 54,971,654 54,975,236 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 7 42,317,704 42,322,285 RGD:13508589
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 3 30,970,037 30,988,987 RGD:13508589
G HYAL2 hyaluronidase 2 JBrowse link 20 39,029,426 39,034,451 RGD:13508589
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G INPP5K inositol polyphosphate-5-phosphatase K JBrowse link 9 45,660,445 45,680,407 RGD:13508589
G INPPL1 inositol polyphosphate phosphatase like 1 JBrowse link 21 25,900,308 25,914,527 RGD:9068941
G IRAK3 interleukin 1 receptor associated kinase 3 JBrowse link 10 8,683,541 8,730,757 RGD:13508589
G KNG1 kininogen 1 JBrowse link 34 19,288,629 19,318,096 RGD:9068941
G LOC483289 CMRF35-like molecule 8 JBrowse link 9 5,952,428 5,976,328 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 29 7,367,617 7,448,862 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 5 40,831,949 40,836,990 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 9 41,467,460 41,679,388 RGD:13508589
G NUP62 nucleoporin 62 JBrowse link 1 106,636,282 106,661,250 RGD:9068941
G PAQR3 progestin and adipoQ receptor family member 3 JBrowse link 32 3,292,034 3,316,914 RGD:13508589
G PRKCD protein kinase C delta JBrowse link 20 36,723,491 36,751,982 RGD:13508589
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 24 36,936,469 37,010,929 RGD:13508589
G PTPN5 protein tyrosine phosphatase non-receptor type 5 JBrowse link 21 41,097,563 41,154,247 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 27 38,084,976 38,101,552 RGD:9068941
G PTPRJ protein tyrosine phosphatase receptor type J JBrowse link 18 41,586,262 41,635,386 RGD:13508589
G RGS14 regulator of G protein signaling 14 JBrowse link 4 35,984,970 35,999,386 RGD:9068941
G RGS2 regulator of G protein signaling 2 JBrowse link 38 6,200,237 6,203,491 RGD:13508589
G SH2B3 SH2B adaptor protein 3 JBrowse link 26 9,033,851 9,073,095 RGD:13508589
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 21 29,714,418 29,719,035 RGD:13508589
G SORL1 sortilin related receptor 1 JBrowse link 5 12,493,750 12,650,530 RGD:13508589
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 19 16,969,869 16,976,573 RGD:13508589
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 22 33,366,139 33,371,102 RGD:13508589
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 2 37,199,890 37,213,710 RGD:13508589
G STK38 serine/threonine kinase 38 JBrowse link 12 5,594,090 5,636,581 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 3 71,396,694 71,430,395 RGD:9068941
negative regulation of MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APC APC regulator of WNT signaling pathway JBrowse link 3 252,052 380,506 RGD:9068941
G ASH1L ASH1 like histone lysine methyltransferase JBrowse link 7 42,046,262 42,227,737 RGD:13508589
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:9068941
G CAV3 caveolin 3 JBrowse link 20 9,384,901 9,398,055 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 20 39,707,672 39,779,094 RGD:13508589
G DUSP1 dual specificity phosphatase 1 JBrowse link 4 39,588,833 39,591,065 RGD:9068941
G DUSP16 dual specificity phosphatase 16 JBrowse link 27 33,728,209 33,831,258 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 9 19,518,302 19,531,000 RGD:9068941
G EFNA1 ephrin A1 JBrowse link 7 42,373,197 42,381,161 RGD:13508589
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
G LEMD2 LEM domain nuclear envelope protein 2 JBrowse link 12 3,114,175 3,131,779 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 9 41,467,460 41,679,388 RGD:9068941
G NF2 neurofibromin 2 JBrowse link 26 22,816,869 22,896,103 RGD:13508589
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 18 25,433,481 25,440,703 RGD:9068941
G P2RX7 purinergic receptor P2X 7 JBrowse link 26 7,928,863 7,983,956 RGD:13508589
G PEBP1 phosphatidylethanolamine binding protein 1 JBrowse link 26 14,522,124 14,526,370 RGD:13508589
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 20 44,826,037 44,838,449 RGD:9068941
G PPEF2 protein phosphatase with EF-hand domain 2 JBrowse link 32 443,495 467,929 RGD:9068941
G PRDM15 PR/SET domain 15 JBrowse link 31 36,220,532 36,285,752 RGD:13508589
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 81,625,288 81,632,175 RGD:13508589
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 27 38,084,976 38,101,552 RGD:9068941
G RNF149 ring finger protein 149 JBrowse link 10 41,621,529 41,648,263 RGD:9068941
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 30 5,594,327 5,716,082 RGD:9068941
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1QBP complement C1q binding protein JBrowse link 5 31,354,665 31,359,672 RGD:13508589
G DHX58 DExH-box helicase 58 JBrowse link 9 20,787,470 20,795,593 RGD:13508589
G RIOK3 RIO kinase 3 JBrowse link 7 64,835,810 64,860,464 RGD:13508589
G TKFC triokinase and FMN cyclase JBrowse link 18 55,051,068 55,064,571 RGD:13508589
negative regulation of NIK/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADGRG3 adhesion G protein-coupled receptor G3 JBrowse link 2 58,780,800 58,805,593 RGD:13508589
G ADIPOR1 adiponectin receptor 1 JBrowse link 7 240,035 254,287 RGD:9068941
G C1QTNF3 C1q and TNF related 3 JBrowse link 4 73,787,706 73,817,410 RGD:9068941
G CAPN1 calpain 1 JBrowse link 18 51,983,266 52,010,831 RGD:9068941
G CCN3 cellular communication network factor 3 JBrowse link 13 18,507,586 18,515,755 RGD:13508589
G CPNE1 copine 1 JBrowse link 24 24,554,636 24,589,748 RGD:9068941
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 2 64,561,684 64,628,829 RGD:9068941
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 35,759,367 35,789,759 RGD:9068941
G FBXW11 F-box and WD repeat domain containing 11 JBrowse link 4 40,238,695 40,363,445 RGD:9068941
G HDAC7 histone deacetylase 7 JBrowse link 27 6,941,287 6,968,370 RGD:9068941
G LITAF lipopolysaccharide induced TNF factor JBrowse link 6 31,229,153 31,259,670 RGD:13508589
G LOC100683370 thymosin beta-4 JBrowse link 1 21,127,694 21,128,346 RGD:9068941
G LOC100855742 NACHT, LRR and PYD domains-containing protein 12-like JBrowse link 1 103,571,756 103,605,692 RGD:9068941
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 21 20,748,452 20,758,236 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 6 37,668,654 37,707,387 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 8 251,776 313,290 RGD:13508589
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A JBrowse link 8 35,336,055 35,384,249 RGD:13508589
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B JBrowse link 10 46,590,110 46,680,792 RGD:9068941
G RASSF2 Ras association domain family member 2 JBrowse link 24 16,736,786 16,779,910 RGD:9068941
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 18 51,550,003 51,558,861 RGD:13508589
G TSPAN6 tetraspanin 6 JBrowse link X 74,499,684 74,510,079 RGD:9068941
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats JBrowse link 30 34,376,072 34,467,278 RGD:13508589
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 15 4,972,369 4,984,218 RGD:13508589
negative regulation of nitric oxide mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 38 321,246 420,262 RGD:13508589
G SPINK1 serine peptidase inhibitor Kazal type 1 JBrowse link 2 42,112,015 42,120,738 RGD:9068941
G THBS1 thrombospondin 1 JBrowse link 30 6,770,212 6,786,875 RGD:13508589
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 11 50,156,089 50,168,379 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 1 30,247,432 30,262,992 RGD:13508589
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERBIN erbb2 interacting protein JBrowse link 2 51,613,344 51,730,868 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 17 51,623,628 51,683,039 RGD:13508589
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 1 30,247,432 30,262,992 RGD:13508589
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAG5 BAG cochaperone 5 JBrowse link 8 71,318,730 71,324,743 RGD:13508589
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:13508589
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 6 7,487,164 7,488,576 RGD:13508589
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 5 40,831,949 40,836,990 RGD:13508589
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 36 20,989,205 21,087,044 RGD:13508589
G NME5 NME/NM23 family member 5 JBrowse link 11 25,772,162 25,792,856 RGD:13508589
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 48,943,472 48,955,158 RGD:9068941
G VNN1 vanin 1 JBrowse link 1 25,678,039 25,704,579 RGD:13508589
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 8 36,614,045 36,656,692 RGD:13508589
G NONO non-POU domain containing octamer binding JBrowse link X 55,618,032 55,632,237 RGD:13508589
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
negative regulation of p38MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 2 64,561,684 64,628,829 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 33 30,016,323 30,253,180 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 4 39,588,833 39,591,065 RGD:13508589
G DUSP10 dual specificity phosphatase 10 JBrowse link 38 16,196,354 16,233,640 RGD:13508589
G EZR ezrin JBrowse link 1 48,160,206 48,210,036 RGD:13508589
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 25 8,972,942 8,998,404 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 17 51,623,628 51,683,039 RGD:13508589
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CRYBA1 crystallin beta A1 JBrowse link 9 43,372,507 43,378,561 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 60,725,887 60,918,242 RGD:9068941
G INPP5E inositol polyphosphate-5-phosphatase E JBrowse link 9 49,061,014 49,071,474 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 11 62,881,840 62,886,676 RGD:9068941
G LOC100855640 butyrophilin subfamily 2 member A2 JBrowse link 35 24,251,221 24,265,040 RGD:13508589
G NCOR1 nuclear receptor corepressor 1 JBrowse link 5 39,687,530 39,837,003 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 6 37,668,654 37,707,387 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 1 108,307,039 108,315,732 RGD:13508589
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 14 664,404 782,376 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 26 24,243,195 24,255,335 RGD:13508589
G SERPINE2 serpin family E member 2 JBrowse link 37 29,699,551 29,750,151 RGD:13508589
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 9 5,661,792 5,679,783 RGD:13508589
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 6 38,905,070 38,915,028 RGD:9068941
G STAMBP STAM binding protein JBrowse link 17 49,194,810 49,221,017 RGD:13508589
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:9068941
negative regulation of protein kinase B signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BANK1 B cell scaffold protein with ankyrin repeats 1 JBrowse link 32 23,322,654 23,603,233 RGD:13508589
G CAVIN3 caveolae associated protein 3 JBrowse link 21 29,661,235 29,663,393 RGD:9068941
G CIB1 calcium and integrin binding 1 JBrowse link 3 53,184,713 53,209,195 RGD:13508589
G CRYBA1 crystallin beta A1 JBrowse link 9 43,372,507 43,378,561 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 20 39,707,672 39,779,094 RGD:13508589
G DDIT3 DNA damage inducible transcript 3 JBrowse link 10 1,606,693 1,612,410 RGD:13508589
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 33 30,016,323 30,253,180 RGD:9068941
G DRD2 dopamine receptor D2 JBrowse link 5 19,732,842 19,795,241 RGD:13508589
G DRD3 dopamine receptor D3 JBrowse link 33 18,369,362 18,414,465 RGD:13508589
G EPHA2 EPH receptor A2 JBrowse link 2 81,534,130 81,561,722 RGD:13508589
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 6 15,792,072 15,796,922 RGD:13508589
G HYAL2 hyaluronidase 2 JBrowse link 20 39,029,426 39,034,451 RGD:13508589
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
G INPP5K inositol polyphosphate-5-phosphatase K JBrowse link 9 45,660,445 45,680,407 RGD:13508589
G KLF4 Kruppel like factor 4 JBrowse link 11 62,881,840 62,886,676 RGD:9068941
G LEMD2 LEM domain nuclear envelope protein 2 JBrowse link 12 3,114,175 3,131,779 RGD:9068941
G LMBRD1 LMBR1 domain containing 1 JBrowse link 12 32,274,056 32,383,737 RGD:9068941
G LOC100855640 butyrophilin subfamily 2 member A2 JBrowse link 35 24,251,221 24,265,040 RGD:13508589
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 18 17,973,058 19,098,785 RGD:13508589
G MIR143 microRNA mir-143 JBrowse link 4 59,534,535 59,534,589 RGD:9068941
G MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) JBrowse link 5 28,949,631 28,957,915 RGD:9068941
G MSTN myostatin JBrowse link 37 729,172 734,255 RGD:13508589
G MTM1 myotubularin 1 JBrowse link X 118,820,644 118,917,166 RGD:13508589
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 2 78,394,013 78,402,032 RGD:13508589
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 1 108,307,039 108,315,732 RGD:13508589
G OTUD3 OTU deubiquitinase 3 JBrowse link 2 78,843,627 78,875,215 RGD:13508589
G PDCD6 programmed cell death 6 JBrowse link 34 11,909,657 11,929,850 RGD:9068941
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 1 14,027,741 14,234,229 RGD:13508589
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 12 19,280,866 19,744,669 RGD:13508589
G PLEKHA1 pleckstrin homology domain containing A1 JBrowse link 28 32,025,791 32,081,824 RGD:13508589
G POU5F1 POU class 5 homeobox 1 JBrowse link 12 860,702 866,099 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 26 37,853,148 37,913,176 RGD:13508589
G PTPRJ protein tyrosine phosphatase receptor type J JBrowse link 18 41,586,262 41,635,386 RGD:9068941
G RACK1 receptor for activated C kinase 1 JBrowse link 11 426,734 431,087 RGD:13508589
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 52,429,204 52,566,775 RGD:9068941
G SFRP5 secreted frizzled related protein 5 JBrowse link 28 10,994,180 10,999,552 RGD:13508589
G SH2B3 SH2B adaptor protein 3 JBrowse link 26 9,033,851 9,073,095 RGD:13508589
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 9 5,661,792 5,679,783 RGD:13508589
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:13508589
G XDH xanthine dehydrogenase JBrowse link 17 24,900,708 24,960,748 RGD:13508589
negative regulation of protein kinase C signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGKD diacylglycerol kinase delta JBrowse link 25 44,851,827 44,961,352 RGD:9068941
G DGKG diacylglycerol kinase gamma JBrowse link 34 18,810,201 19,016,037 RGD:9068941
G GPD1L glycerol-3-phosphate dehydrogenase 1 like JBrowse link 23 12,568,914 12,631,903 RGD:9068941
G LOC100855913 myeloid-associated differentiation marker JBrowse link 1 103,515,509 103,522,232 RGD:13508589
G MYADM myeloid associated differentiation marker JBrowse link 1 103,315,606 103,322,329 RGD:13508589
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 1 14,027,741 14,234,229 RGD:9068941
negative regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 2 36,614,799 36,639,281 RGD:9068941
G ARHGAP24 Rho GTPase activating protein 24 JBrowse link 32 8,838,567 9,574,712 RGD:13508589
G ARHGAP44 Rho GTPase activating protein 44 JBrowse link 5 36,790,059 36,957,932 RGD:13508589
G NF1 neurofibromin 1 JBrowse link 9 41,467,460 41,679,388 RGD:13508589
G STMN3 stathmin 3 JBrowse link 24 47,209,738 47,220,146 RGD:9068941
negative regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DAB2IP DAB2 interacting protein JBrowse link 9 60,725,887 60,918,242 RGD:9068941
G DGKZ diacylglycerol kinase zeta JBrowse link 18 43,088,169 43,103,820 RGD:9068941
G EPHB2 EPH receptor B2 JBrowse link 2 76,427,112 76,551,494 RGD:9068941
G FBP1 fructose-bisphosphatase 1 JBrowse link 1 72,099,886 72,125,266 RGD:13508589
G LZTR1 leucine zipper like transcription regulator 1 JBrowse link 26 30,501,793 30,519,698 RGD:13508589
G MAPKAP1 MAPK associated protein 1 JBrowse link 9 57,447,115 57,699,979 RGD:9068941
G MFN2 mitofusin 2 JBrowse link 2 84,284,719 84,310,715 RGD:13508589
G NF1 neurofibromin 1 JBrowse link 9 41,467,460 41,679,388 RGD:9068941
G NUP62 nucleoporin 62 JBrowse link 1 106,636,282 106,661,250 RGD:9068941
G PPP2CB protein phosphatase 2 catalytic subunit beta JBrowse link 16 33,532,703 33,567,011 RGD:9068941
G RABGEF1 RAB guanine nucleotide exchange factor 1 JBrowse link 6 1,064,694 1,159,906 RGD:9068941
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 52,429,204 52,566,775 RGD:9068941
G RASA1 RAS p21 protein activator 1 JBrowse link 3 21,068,182 21,177,288 RGD:13508589
G RASA2 RAS p21 protein activator 2 JBrowse link 23 37,298,422 37,509,234 RGD:13508589
G RASA3 RAS p21 protein activator 3 JBrowse link 22 61,093,762 61,202,209 RGD:13508589
G RASA4B RAS p21 protein activator 4B JBrowse link 6 7,683,101 7,705,994 RGD:13508589
G RASAL1 RAS protein activator like 1 JBrowse link 26 10,503,309 10,532,217 RGD:13508589
G RASAL3 RAS protein activator like 3 JBrowse link 20 46,733,072 46,743,657 RGD:13508589
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 19 16,969,869 16,976,573 RGD:13508589
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 22 33,366,139 33,371,102 RGD:13508589
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 2 37,199,890 37,213,710 RGD:13508589
G STAMBP STAM binding protein JBrowse link 17 49,194,810 49,221,017 RGD:13508589
G SYNGAP1 synaptic Ras GTPase activating protein 1 JBrowse link 12 2,829,274 2,862,888 RGD:13508589
G TGFB2 transforming growth factor beta 2 JBrowse link 38 13,430,832 13,511,655 RGD:9068941
G TIMP2 TIMP metallopeptidase inhibitor 2 JBrowse link 9 2,521,882 2,533,883 RGD:9068941
G TNK1 tyrosine kinase non receptor 1 JBrowse link 5 32,320,029 32,326,829 RGD:9068941
G TRIM67 tripartite motif containing 67 JBrowse link 4 8,211,013 8,259,907 RGD:9068941
negative regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 7 20,696,659 20,735,362 RGD:9068941
G ADRA1A adrenoceptor alpha 1A JBrowse link 25 30,690,959 30,801,484 RGD:9068941
G ADRA1B adrenoceptor alpha 1B JBrowse link 4 50,676,816 50,724,999 RGD:9068941
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 2 36,614,799 36,639,281 RGD:9068941
G ARHGAP35 Rho GTPase activating protein 35 JBrowse link 1 108,952,836 109,034,329 RGD:13508589
G ARHGAP42 Rho GTPase activating protein 42 JBrowse link 21 597,306 842,086 RGD:9068941
G BCL6 BCL6 transcription repressor JBrowse link 34 20,112,302 20,135,705 RGD:13508589
G CCDC125 coiled-coil domain containing 125 JBrowse link 2 54,353,523 54,383,867 RGD:13508589
G CUL3 cullin 3 JBrowse link 25 37,730,903 37,819,851 RGD:13508589
G DLC1 DLC1 Rho GTPase activating protein JBrowse link 16 36,531,754 36,943,033 RGD:13508589
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G HEG1 heart development protein with EGF like domains 1 JBrowse link 33 27,982,127 28,044,379 RGD:13508589
G ITGA3 integrin subunit alpha 3 JBrowse link 9 26,065,792 26,095,649 RGD:13508589
G ITGB1 integrin subunit beta 1 JBrowse link 2 3,728,472 3,757,696 RGD:13508589
G KANK1 KN motif and ankyrin repeat domains 1 JBrowse link 1 89,446,340 89,618,716 RGD:9068941
G KCTD10 potassium channel tetramerization domain containing 10 JBrowse link 26 17,592,157 17,625,384 RGD:13508589
G KCTD13 potassium channel tetramerization domain containing 13 JBrowse link 6 17,945,541 17,959,421 RGD:13508589
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 14 55,599,047 55,711,626 RGD:13508589
G MYOC myocilin JBrowse link 7 27,335,314 27,346,821 RGD:13508589
G RASIP1 Ras interacting protein 1 JBrowse link 1 107,583,169 107,597,683 RGD:13508589
G RIPOR1 RHO family interacting cell polarization regulator 1 JBrowse link 5 81,879,359 81,888,613 RGD:9068941
G RIPOR2 RHO family interacting cell polarization regulator 2 JBrowse link 35 22,823,053 23,041,765 RGD:13508589
G SCAI suppressor of cancer cell invasion JBrowse link 9 57,924,995 58,090,837 RGD:13508589
G STMN1 stathmin 1 JBrowse link 2 74,035,462 74,043,352 RGD:13508589
G TNFAIP1 TNF alpha induced protein 1 JBrowse link 9 42,588,009 42,597,961 RGD:13508589
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1QBP complement C1q binding protein JBrowse link 5 31,354,665 31,359,672 RGD:13508589
G DHX58 DExH-box helicase 58 JBrowse link 9 20,787,470 20,795,593 RGD:13508589
G GPATCH3 G-patch domain containing 3 JBrowse link 2 73,243,178 73,250,926 RGD:13508589
G NLRX1 NLR family member X1 JBrowse link 5 14,692,621 14,705,214 RGD:13508589
G NPLOC4 NPL4 homolog, ubiquitin recognition factor JBrowse link 9 538,087 604,898 RGD:13508589
G RNF125 ring finger protein 125 JBrowse link 7 57,570,779 57,607,485 RGD:13508589
G SEC14L1 SEC14 like lipid binding 1 JBrowse link 9 3,683,328 3,740,271 RGD:9068941
G UFD1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 26 29,739,062 29,763,315 RGD:13508589
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALM1 calmodulin 1 JBrowse link 8 61,398,231 61,408,874 RGD:9068941
G CALM2 calmodulin 2 JBrowse link 10 49,299,698 49,314,533 RGD:9068941
G CALM3 calmodulin 3 JBrowse link 1 109,284,729 109,294,491 RGD:9068941
G CASQ2 calsequestrin 2 JBrowse link 17 53,233,966 53,299,093 RGD:13508589
G CLIC2 chloride intracellular channel 2 JBrowse link X 123,268,867 123,291,467 RGD:13508589
G FKBP1A FKBP prolyl isomerase 1A JBrowse link 24 19,618,581 19,643,685 RGD:9068941
G FKBP1B FKBP prolyl isomerase 1B JBrowse link 17 18,534,295 18,544,973 RGD:13508589
G GSTO1 glutathione S-transferase omega 1 JBrowse link 28 16,569,421 16,579,239 RGD:13508589
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 32 11,383,441 11,437,603 RGD:13508589
G SRI sorcin JBrowse link 14 14,257,375 14,274,816 RGD:9068941
negative regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 30 10,514,633 10,517,963 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 1 108,307,039 108,315,732 RGD:13508589
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 9 38,271,419 38,346,103 RGD:9068941
G RNF34 ring finger protein 34 JBrowse link 26 7,746,460 7,767,967 RGD:13508589
G SENP2 SUMO specific peptidase 2 JBrowse link 34 18,325,373 18,357,152 RGD:9068941
negative regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGAP12 Rho GTPase activating protein 12 JBrowse link 2 14,959,556 15,114,710 RGD:13508589
G ARHGAP25 Rho GTPase activating protein 25 JBrowse link 10 67,597,527 67,687,721 RGD:9068941
G CD2AP CD2 associated protein JBrowse link 12 15,538,215 15,683,619 RGD:13508589
G CGNL1 cingulin like 1 JBrowse link 30 22,529,971 22,715,776 RGD:13508589
G CYRIB CYFIP related Rac1 interactor B JBrowse link 13 26,942,036 27,056,547 RGD:13508589
G SH3BP1 SH3 domain binding protein 1 JBrowse link 10 26,953,993 26,966,417 RGD:9068941
G SLIT2 slit guidance ligand 2 JBrowse link 3 88,964,707 89,311,817 RGD:9068941
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP10 dual specificity phosphatase 10 JBrowse link 38 16,196,354 16,233,640 RGD:9068941
G FOXM1 forkhead box M1 JBrowse link 27 41,894,605 41,905,656 RGD:13508589
G FOXO1 forkhead box O1 JBrowse link 25 603,433 706,961 RGD:13508589
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G IGBP1 immunoglobulin binding protein 1 JBrowse link X 54,558,515 54,612,029 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 13 25,200,772 25,205,309 RGD:13508589
G PBK PDZ binding kinase JBrowse link 25 29,751,805 29,781,806 RGD:13508589
G QARS1 glutaminyl-tRNA synthetase 1 JBrowse link 20 40,077,856 40,085,100 RGD:13508589
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1S1 AKT1 substrate 1 JBrowse link 1 106,686,349 106,694,854 RGD:13508589
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 21 36,254,235 36,323,915 RGD:13508589
G CRYBA1 crystallin beta A1 JBrowse link 9 43,372,507 43,378,561 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 4 22,916,718 22,918,893 RGD:13508589
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 26 24,629,369 24,754,728 RGD:13508589
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 13 18,859,526 18,993,464 RGD:13508589
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 1 36,835,775 36,977,653 RGD:9068941
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 11 19,979,294 20,134,341 RGD:13508589
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 1 112,129,116 112,138,714 RGD:13508589
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 8 36,614,045 36,656,692 RGD:13508589
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 26 9,380,551 9,420,564 RGD:13508589
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 3 57,735,935 57,770,369 RGD:13508589
G MTM1 myotubularin 1 JBrowse link X 118,820,644 118,917,166 RGD:13508589
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 20 39,005,699 39,009,183 RGD:13508589
G NPRL3 NPR3 like, GATOR1 complex subunit JBrowse link 6 40,351,757 40,394,599 RGD:13508589
G PDCD6 programmed cell death 6 JBrowse link 34 11,909,657 11,929,850 RGD:9068941
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 4 68,579,061 68,614,548 RGD:9068941
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 52,809,792 52,855,072 RGD:13508589
G SH3BP4 SH3 domain binding protein 4 JBrowse link 25 46,049,631 46,133,065 RGD:13508589
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G TBC1D7 TBC1 domain family member 7 JBrowse link 35 12,765,953 12,789,393 RGD:13508589
G TMEM127 transmembrane protein 127 JBrowse link 17 34,512,753 34,527,208 RGD:13508589
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 20 55,098,121 55,111,228 RGD:13508589
G TSC1 TSC complex subunit 1 JBrowse link 9 51,409,307 51,459,546 RGD:13508589
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:13508589
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 30 9,869,769 10,006,994 RGD:13508589
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 12 11,167,286 11,296,817 RGD:13508589
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 5 24,180,129 24,297,207 RGD:13508589
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 14 52,363,629 52,456,440 RGD:13508589
G C10H12orf66 chromosome 10 C12orf66 homolog JBrowse link 10 6,977,602 6,998,204 RGD:13508589
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 26 23,439,472 23,443,950 RGD:13508589
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 6 5,565,723 5,602,799 RGD:13508589
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 26 24,629,369 24,754,728 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 11 19,979,294 20,134,341 RGD:13508589
G FNIP2 folliculin interacting protein 2 JBrowse link 15 55,871,782 55,962,676 RGD:13508589
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 27 41,933,741 41,944,464 RGD:13508589
G KPTN kaptin, actin binding protein JBrowse link 1 108,535,140 108,544,405 RGD:13508589
G LOC106559493 small regulatory polypeptide of amino acid response-like JBrowse link 11 52,424,607 52,427,288 RGD:9068941
G RNF152 ring finger protein 152 JBrowse link 1 14,914,508 15,001,843 RGD:13508589
G SESN1 sestrin 1 JBrowse link 12 65,958,995 66,057,369 RGD:13508589
G SESN2 sestrin 2 JBrowse link 2 72,151,464 72,168,861 RGD:13508589
G SESN3 sestrin 3 JBrowse link 21 5,827,957 5,899,540 RGD:13508589
G STK11 serine/threonine kinase 11 JBrowse link 20 57,558,966 57,579,163 RGD:13508589
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 15 16,729,068 16,780,549 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:9068941
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TSPAN6 tetraspanin 6 JBrowse link X 74,499,684 74,510,079 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16042
    cellular process 15297
      signal transduction 5381
        negative regulation of signal transduction 1189
          negative regulation of intracellular signal transduction 525
            negative regulation of I-kappaB kinase/NF-kappaB signaling + 50
            negative regulation of MAPK cascade + 173
            negative regulation of NIK/NF-kappaB signaling 23
            negative regulation of TOR signaling + 44
            negative regulation of cAMP-mediated signaling + 29
            negative regulation of cGMP-mediated signaling 6
            negative regulation of calcium-mediated signaling + 31
            negative regulation of hippo signaling 11
            negative regulation of intrinsic apoptotic signaling pathway + 100
            negative regulation of mitotic spindle assembly checkpoint signaling 0
            negative regulation of nitric oxide mediated signal transduction 3
            negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
            negative regulation of phosphatidylinositol 3-kinase signaling 15
            negative regulation of phosphorelay signal transduction system + 0
            negative regulation of protein kinase B signaling 42
            negative regulation of protein kinase C signaling 6
            negative regulation of protein kinase D signaling 0
            negative regulation of signal transduction by p53 class mediator + 31
            negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint 0
            negative regulation of small GTPase mediated signal transduction + 63
            negative regulation of stress-activated protein kinase signaling cascade + 45
            negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 16042
    biological regulation 11411
      regulation of biological process 10830
        regulation of cellular process 10368
          signal transduction 5381
            regulation of signal transduction 2795
              negative regulation of signal transduction 1189
                negative regulation of intracellular signal transduction 525
                  negative regulation of I-kappaB kinase/NF-kappaB signaling + 50
                  negative regulation of MAPK cascade + 173
                  negative regulation of NIK/NF-kappaB signaling 23
                  negative regulation of TOR signaling + 44
                  negative regulation of cAMP-mediated signaling + 29
                  negative regulation of cGMP-mediated signaling 6
                  negative regulation of calcium-mediated signaling + 31
                  negative regulation of hippo signaling 11
                  negative regulation of intrinsic apoptotic signaling pathway + 100
                  negative regulation of mitotic spindle assembly checkpoint signaling 0
                  negative regulation of nitric oxide mediated signal transduction 3
                  negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
                  negative regulation of phosphatidylinositol 3-kinase signaling 15
                  negative regulation of phosphorelay signal transduction system + 0
                  negative regulation of protein kinase B signaling 42
                  negative regulation of protein kinase C signaling 6
                  negative regulation of protein kinase D signaling 0
                  negative regulation of signal transduction by p53 class mediator + 31
                  negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint 0
                  negative regulation of small GTPase mediated signal transduction + 63
                  negative regulation of stress-activated protein kinase signaling cascade + 45
                  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.