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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intracellular signal transduction
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Accession:GO:1902532 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
Synonyms:exact_synonym: down regulation of intracellular signal transduction;   down regulation of intracellular signaling chain;   downregulation of intracellular signal transduction;   downregulation of intracellular signaling chain;   negative regulation of intracellular protein kinase cascade;   negative regulation of intracellular signaling cascade;   negative regulation of intracellular signaling chain
 narrow_synonym: down regulation of intracellular signal transduction pathway;   downregulation of intracellular signal transduction pathway;   downregulation of intracellular signaling cascade;   downregulation of signal transmission via intracellular cascade;   inhibition of intracellular signal transduction;   inhibition of intracellular signal transduction pathway;   inhibition of intracellular signaling cascade;   inhibition of intracellular signaling chain;   inhibition of signal transmission via intracellular cascade;   negative regulation of intracellular signal transduction pathway;   negative regulation of signal transmission via intracellular cascade
 related_synonym: down regulation of intracellular signaling pathway;   down regulation of signal transduction via intracellular signaling cascade;   down-regulation of intracellular signaling cascade;   down-regulation of signal transmission via intracellular cascade;   downregulation of intracellular signaling pathway;   downregulation of signal transduction via intracellular signaling cascade;   inhibition of intracellular signaling pathway;   inhibition of signal transduction via intracellular signaling cascade;   negative regulation of intracellular signaling pathway;   negative regulation of signal transduction via intracellular signaling cascade
 alt_id: GO:0010741


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negative regulation of intracellular signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDIT4 DNA damage inducible transcript 4 JBrowse link 14 75,117,708 75,119,907 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 4 75,793,273 75,903,710 RGD:9068941
inactivation of MAPK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:14298760
G DUSP1 dual specificity phosphatase 1 JBrowse link 16 51,457,924 51,461,095 RGD:14298760
G DUSP10 dual specificity phosphatase 10 JBrowse link 10 10,866,446 10,905,852 RGD:14298760
G DUSP14 dual specificity phosphatase 14 JBrowse link 12 38,941,052 38,978,568 RGD:14298760
G DUSP16 dual specificity phosphatase 16 JBrowse link 5 59,869,902 59,961,839 RGD:14298760
G DUSP18 dual specificity phosphatase 18 JBrowse link 14 47,534,152 47,550,953 RGD:14298760
G DUSP19 dual specificity phosphatase 19 JBrowse link 15 88,549,250 88,574,978 RGD:9068941
G DUSP2 dual specificity phosphatase 2 JBrowse link 3 47,052,443 47,054,816 RGD:14298760
G DUSP21 dual specificity phosphatase 21 JBrowse link X 39,929,707 39,930,539 RGD:14298760
G DUSP3 dual specificity phosphatase 3 JBrowse link 12 19,336,308 19,349,739 RGD:14298760
G DUSP4 dual specificity phosphatase 4 JBrowse link 15 55,491,084 55,508,460 RGD:14298760
G DUSP5 dual specificity phosphatase 5 JBrowse link 14 120,906,340 120,919,398 RGD:14298760
G DUSP6 dual specificity phosphatase 6 JBrowse link 5 93,303,058 93,307,510 RGD:14298760
G DUSP8 dual specificity phosphatase 8 JBrowse link 2 1,006,589 1,022,444 RGD:14298760
G DUSP9 dual specificity phosphatase 9 JBrowse link X 124,404,852 124,414,246 RGD:14298760
G LAX1 lymphocyte transmembrane adaptor 1 JBrowse link 9 64,460,548 64,473,232 RGD:14298760
G POC1A POC1 centriolar protein A JBrowse link 13 34,227,884 34,308,099 RGD:14298760
G PRKCA protein kinase C alpha JBrowse link 12 12,882,287 13,268,647 RGD:9068941
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 1 132,903,103 133,016,725 RGD:14298760
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 3 76,527,646 76,649,652 RGD:14298760
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 6 47,302,211 47,312,034 RGD:14298760
inactivation of MAPKK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EPHB2 EPH receptor B2 JBrowse link 6 80,649,098 80,849,979 RGD:14298760
G IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:14298760
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARRDC3 arrestin domain containing 3 JBrowse link 2 98,430,451 98,444,835 RGD:14298760
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 9 64,336,354 64,445,669 RGD:14298760
G GNAI2 G protein subunit alpha i2 JBrowse link 13 32,705,326 32,733,804 RGD:9068941
G PDE4B phosphodiesterase 4B JBrowse link 6 146,167,262 146,720,105 RGD:9068941
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLP1 amyloid beta precursor like protein 1 JBrowse link 6 45,285,698 45,295,355 RGD:14298760
G GRK2 G protein-coupled receptor kinase 2 JBrowse link 2 5,209,435 5,227,543 RGD:9068941
G GRK5 G protein-coupled receptor kinase 5 JBrowse link 14 129,113,933 129,351,135 RGD:9068941
G MRAP melanocortin 2 receptor accessory protein JBrowse link 13 195,950,949 195,973,501 RGD:9068941
G MRAP2 melanocortin 2 receptor accessory protein 2 JBrowse link 1 53,248,311 53,318,111 RGD:14298760
G OPRL1 opioid related nociceptin receptor 1 JBrowse link 17 62,905,700 62,913,018 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 1 12,634,125 12,702,295 RGD:9068941
G PTGER3 prostaglandin E receptor 3 JBrowse link 6 141,958,955 142,160,437 RGD:9068941
negative regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GIT1 GIT ArfGAP 1 JBrowse link 12 45,768,172 45,783,652 RGD:9068941
negative regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTN3 actinin alpha 3 JBrowse link 2 5,860,386 5,873,779 RGD:9068941
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 9 64,336,354 64,445,669 RGD:14298760
G CHP1 calcineurin like EF-hand protein 1 JBrowse link 1 130,073,919 130,112,461 RGD:14298760
G CMYA5 cardiomyopathy associated 5 JBrowse link 2 88,391,104 88,506,336 RGD:9068941
G DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 JBrowse link 5 32,047,614 32,064,231 RGD:14298760
G FHL2 four and a half LIM domains 2 JBrowse link 3 49,389,900 49,448,459 RGD:14298760
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G HOMER2 homer scaffold protein 2 JBrowse link 7 52,001,253 52,104,426 RGD:14298760
G HOMER3 homer scaffold protein 3 JBrowse link 2 58,913,949 58,922,474 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 12 60,144,138 60,148,743 RGD:14298760
G MTOR mechanistic target of rapamycin kinase JBrowse link 6 71,286,989 71,412,913 RGD:14298760
G MYOZ1 myozenin 1 JBrowse link 14 76,445,109 76,453,014 RGD:14298760
G MYOZ2 myozenin 2 JBrowse link 8 104,578,942 104,609,367 RGD:14298760
G PRNP prion protein JBrowse link 17 13,694,195 13,705,126 RGD:14298760
G RCAN1 regulator of calcineurin 1 JBrowse link 13 198,106,256 198,205,727 RGD:9068941
G TBC1D10C TBC1 domain family member 10C JBrowse link 2 5,112,462 5,118,829 RGD:14298760
negative regulation of calcium-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD22 CD22 molecule JBrowse link 6 44,820,593 44,834,392 RGD:9068941
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 JBrowse link 13 61,068,131 61,398,918 RGD:9068941
G LOC100513863 sialic acid-binding Ig-like lectin 10 JBrowse link 6 58,466,741 58,474,972 RGD:14298760
G SLA2 Src like adaptor 2 JBrowse link 17 39,875,625 39,904,838 RGD:9068941
negative regulation of CAMKK-AMPK signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGLN1 egl-9 family hypoxia inducible factor 1 JBrowse link 14 59,113,527 59,168,421 RGD:9068941
negative regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLNR apelin receptor RGD:14298760
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme JBrowse link 2 77,761,587 77,768,332 RGD:14298760
G CRHR2 corticotropin releasing hormone receptor 2 JBrowse link 18 42,251,755 42,296,457 RGD:9068941
G CRTC3 CREB regulated transcription coactivator 3 JBrowse link 7 53,146,317 53,255,985 RGD:14298760
G LPAR1 lysophosphatidic acid receptor 1 JBrowse link 1 251,811,583 251,979,828 RGD:9068941
G MGRN1 mahogunin ring finger 1 JBrowse link 3 37,694,798 37,748,106 RGD:14298760
G NPY2R neuropeptide Y receptor Y2 JBrowse link 8 74,039,959 74,048,398 RGD:9068941
G NUCB2 nucleobindin 2 JBrowse link 2 41,782,594 41,829,829 RGD:9068941
G OPRL1 opioid related nociceptin receptor 1 JBrowse link 17 62,905,700 62,913,018 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 1 12,634,125 12,702,295 RGD:14298760
G PDE10A phosphodiesterase 10A JBrowse link 1 3,120,418 3,394,236 RGD:9068941
G PDE11A phosphodiesterase 11A JBrowse link 15 83,366,082 83,784,266 RGD:14298760
G PDE2A phosphodiesterase 2A JBrowse link 9 7,136,637 7,227,966 RGD:14298760
G PDE3A phosphodiesterase 3A JBrowse link 5 52,413,503 52,737,771 RGD:14298760
G PDE3B phosphodiesterase 3B JBrowse link 2 44,416,934 44,614,075 RGD:9068941
G PDE4D phosphodiesterase 4D JBrowse link 16 37,897,300 39,406,534 RGD:14298760
G RGS2 regulator of G protein signaling 2 JBrowse link 10 936,836 940,083 RGD:14298760
G RNF157 ring finger protein 157 JBrowse link 12 5,225,978 5,306,197 RGD:14298760
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 2 136,652,764 136,667,213 RGD:14298760
negative regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTNR1B melatonin receptor 1B JBrowse link 9 25,556,756 25,557,792 RGD:9068941
G PDE10A phosphodiesterase 10A JBrowse link 1 3,120,418 3,394,236 RGD:14298760
G PDE11A phosphodiesterase 11A JBrowse link 15 83,366,082 83,784,266 RGD:14298760
G PDE2A phosphodiesterase 2A JBrowse link 9 7,136,637 7,227,966 RGD:14298760
G PDZD3 PDZ domain containing 3 JBrowse link 9 46,401,377 46,409,804 RGD:14298760
G THBS1 thrombospondin 1 JBrowse link 1 131,728,781 131,746,098 RGD:14298760
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD44 CD44 molecule JBrowse link 2 25,788,699 25,884,209 RGD:14298760
G CD74 CD74 molecule JBrowse link 2 151,402,210 151,409,924 RGD:14298760
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link 13 201,008,506 201,159,946 RGD:14298760
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 9 67,268,600 67,279,617 RGD:14298760
G KDM1A lysine demethylase 1A JBrowse link 6 80,903,407 80,971,875 RGD:14298760
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 15 66,649,363 66,699,647 RGD:14298760
G MDM2 MDM2 proto-oncogene JBrowse link 5 33,105,717 33,137,602 RGD:14298760
G MIF macrophage migration inhibitory factor JBrowse link 14 49,840,303 49,841,063 RGD:14298760
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 88,540,261 88,548,593 RGD:14298760
G PTTG1IP PTTG1 interacting protein JBrowse link 13 207,493,656 207,507,089 RGD:14298760
G SENP2 SUMO specific peptidase 2 JBrowse link 13 123,429,915 123,469,913 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G SNAI1 snail family transcriptional repressor 1 JBrowse link 17 51,546,446 51,552,498 RGD:14298760
G SNAI2 snail family transcriptional repressor 2 JBrowse link 4 79,264,880 79,268,475 RGD:14298760
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 9 88,286,911 88,290,131 RGD:9068941
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCBP4 poly(rC) binding protein 4 JBrowse link 13 34,090,015 34,099,959 RGD:9068941
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:14298760
G CREB3 cAMP responsive element binding protein 3 JBrowse link 1 236,450,573 236,456,381 RGD:14298760
G CREB3L1 cAMP responsive element binding protein 3 like 1 JBrowse link 2 16,186,206 16,220,948 RGD:9068941
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 JBrowse link 4 682,823 686,144 RGD:14298760
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 6 18,901,171 18,913,427 RGD:14298760
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 125,035,575 125,056,445 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 5 71,800,337 71,945,828 RGD:14298760
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 13 130,624,771 130,718,345 RGD:14298760
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
G PDX1 pancreatic and duodenal homeobox 1 JBrowse link 11 5,303,609 5,309,063 RGD:14298760
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 17 52,017,100 52,086,747 RGD:14298760
G SELENOS selenoprotein S JBrowse link 1 139,829,002 139,836,923 RGD:14298760
G SYVN1 synoviolin 1 JBrowse link 2 7,059,444 7,066,617 RGD:14298760
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 5 15,674,028 15,692,944 RGD:14298760
G TXNDC12 thioredoxin domain containing 12 JBrowse link 6 160,136,744 160,168,225 RGD:14298760
G WFS1 wolframin ER transmembrane glycoprotein JBrowse link 8 4,362,678 4,405,185 RGD:14298760
G XBP1 X-box binding protein 1 JBrowse link 14 46,011,239 46,016,526 RGD:14298760
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HYOU1 hypoxia up-regulated 1 JBrowse link 9 46,264,929 46,277,056 RGD:14298760
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:14298760
negative regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:14298760
G ACE2 angiotensin I converting enzyme 2 JBrowse link X 12,099,849 12,152,204 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 13 124,633,906 124,646,237 RGD:14298760
G ARRB1 arrestin beta 1 JBrowse link 9 9,516,944 9,597,446 RGD:9068941
G ATF3 activating transcription factor 3 JBrowse link 9 130,772,259 130,829,678 RGD:14298760
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 7 20,954,229 20,968,390 RGD:14298760
G C13H3orf33 chromosome 13 C3orf33 homolog JBrowse link 13 95,658,531 95,673,882 RGD:9068941
G C1QL4 complement C1q like 4 JBrowse link 5 15,308,307 15,311,734 RGD:14298760
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 JBrowse link 6 78,730,204 78,734,232 RGD:9068941
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:9068941
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit JBrowse link 9 6,427,832 6,431,881 RGD:9068941
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 142,803,697 142,937,124 RGD:9068941
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit JBrowse link 8 31,430,933 31,456,385 RGD:9068941
G CNKSR3 CNKSR family member 3 JBrowse link 1 12,297,740 12,396,946 RGD:14298760
G COPS3 COP9 signalosome subunit 3 JBrowse link 12 61,000,562 61,023,920 RGD:14298760
G CRYBA1 crystallin beta A1 JBrowse link 12 45,466,051 45,473,110 RGD:9068941
G CSK C-terminal Src kinase JBrowse link 7 58,736,473 58,755,034 RGD:9068941
G DAB2 DAB adaptor protein 2 JBrowse link 16 24,590,638 24,776,937 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:14298760
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 13 132,819,931 133,084,880 RGD:14298760
G DMD dystrophin JBrowse link X 27,028,223 29,650,728 RGD:9068941
G DUSP1 dual specificity phosphatase 1 JBrowse link 16 51,457,924 51,461,095 RGD:9068941
G DUSP10 dual specificity phosphatase 10 JBrowse link 10 10,866,446 10,905,852 RGD:14298760
G DUSP26 dual specificity phosphatase 26 RGD:14298760
G DUSP3 dual specificity phosphatase 3 JBrowse link 12 19,336,308 19,349,739 RGD:14298760
G DUSP4 dual specificity phosphatase 4 JBrowse link 15 55,491,084 55,508,460 RGD:14298760
G DUSP6 dual specificity phosphatase 6 JBrowse link 5 93,303,058 93,307,510 RGD:14298760
G DUSP9 dual specificity phosphatase 9 JBrowse link X 124,404,852 124,414,246 RGD:14298760
G EIF3A eukaryotic translation initiation factor 3 subunit A JBrowse link 14 128,967,645 129,007,168 RGD:9068941
G EMILIN1 elastin microfibril interfacer 1 JBrowse link 3 112,031,910 112,039,928 RGD:9068941
G EPHB2 EPH receptor B2 JBrowse link 6 80,649,098 80,849,979 RGD:14298760
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 6 68,667,651 68,682,629 RGD:9068941
G EZR ezrin JBrowse link 1 8,403,362 8,452,750 RGD:14298760
G FBLN1 fibulin 1 JBrowse link 5 3,839,498 3,927,178 RGD:14298760
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 3 711,427 715,982 RGD:14298760
G IGF1 insulin like growth factor 1 JBrowse link 5 81,762,027 81,909,253 RGD:9068941
G ITGB1BP1 integrin subunit beta 1 binding protein 1 JBrowse link 3 126,905,779 126,921,961 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 1 248,604,817 248,609,574 RGD:9068941
G LIF LIF interleukin 6 family cytokine JBrowse link 14 47,221,540 47,239,513 RGD:14298760
G LMO3 LIM domain only 3 JBrowse link 5 56,056,885 56,118,813 RGD:9068941
G LOC100516390 ankyrin repeat domain-containing protein 26 JBrowse link 10 48,694,806 48,795,783 RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 4 75,793,273 75,903,710 RGD:14298760
G NDRG2 NDRG family member 2 JBrowse link 7 78,111,736 78,121,216 RGD:14298760
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 6 56,402,617 56,425,038 RGD:14298760
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 2 90,001 97,441 RGD:9068941
G PHB prohibitin JBrowse link 12 25,596,520 25,609,693 RGD:14298760
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 1 158,642,810 158,863,643 RGD:9068941
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 2 68,715,898 68,729,471 RGD:14298760
G PSCA prostate stem cell antigen JBrowse link 4 1,479,872 1,484,245 RGD:14298760
G PTEN phosphatase and tensin homolog JBrowse link 14 99,929,590 100,021,619 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 17 52,017,100 52,086,747 RGD:14298760
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 6 96,769,862 96,847,136 RGD:14298760
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 10 21,482,984 21,601,627 RGD:14298760
G PTPRR protein tyrosine phosphatase receptor type R JBrowse link 5 34,794,970 35,048,550 RGD:9068941
G RANBP9 RAN binding protein 9 JBrowse link 7 9,976,094 10,057,757 RGD:14298760
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 1 271,494,243 271,624,609 RGD:14298760
G RGS14 regulator of G protein signaling 14 JBrowse link 2 80,574,411 80,589,998 RGD:9068941
G RPS6KA6 ribosomal protein S6 kinase A6 JBrowse link X 67,234,684 67,415,114 RGD:9068941
G SEMA6A semaphorin 6A JBrowse link 2 120,560,095 120,687,597 RGD:9068941
G SIRPA signal regulatory protein alpha JBrowse link 17 33,566,270 33,611,375 RGD:9068941
G SIRT3 sirtuin 3 JBrowse link 2 38,465 55,074 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 12 6,466,138 6,483,539 RGD:14298760
G SMAD4 SMAD family member 4 JBrowse link 1 100,521,843 100,633,501 RGD:14298760
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 1 132,903,103 133,016,725 RGD:14298760
G SPRED2 sprouty related EVH1 domain containing 2 JBrowse link 3 76,527,646 76,649,652 RGD:9068941
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 6 47,302,211 47,312,034 RGD:9068941
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 8 100,449,476 100,863,780 RGD:14298760
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 11 52,153,695 52,158,766 RGD:14298760
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 2 143,877,334 143,891,280 RGD:14298760
G SYNJ2BP synaptojanin 2 binding protein JBrowse link 7 93,906,182 93,974,336 RGD:14298760
G TBC1D10C TBC1 domain family member 10C JBrowse link 2 5,112,462 5,118,829 RGD:14298760
G TIMP3 TIMP metallopeptidase inhibitor 3 JBrowse link 5 12,185,816 12,242,599 RGD:14298760
G TLR4 toll like receptor 4 JBrowse link 1 258,044,610 258,054,641 RGD:9068941
G TNIP1 TNFAIP3 interacting protein 1 JBrowse link 16 71,926,038 71,979,969 RGD:14298760
G VRK3 VRK serine/threonine kinase 3 JBrowse link 6 54,973,734 55,041,607 RGD:14298760
G WNK2 WNK lysine deficient protein kinase 2 JBrowse link 3 42,711,388 42,837,650 RGD:14298760
G XBP1 X-box binding protein 1 JBrowse link 14 46,011,239 46,016,526 RGD:9068941
negative regulation of ERK5 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 12 60,144,138 60,148,743 RGD:9068941
negative regulation of hippo signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AJUBA ajuba LIM protein JBrowse link 7 76,063,009 76,072,884 RGD:14298760
G DLG5 discs large MAGUK scaffold protein 5 JBrowse link 14 80,249,693 80,377,496 RGD:9068941
G LIMD1 LIM domains containing 1 JBrowse link 13 28,730,192 28,811,584 RGD:14298760
G MAP2K3 mitogen-activated protein kinase kinase 3 JBrowse link 12 61,396,337 61,417,333 RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 7 31,791,398 31,861,544 RGD:9068941
G MARK3 microtubule affinity regulating kinase 3 RGD:14298760
G VGLL4 vestigial like family member 4 JBrowse link 13 67,698,082 67,873,119 RGD:9068941
G WTIP WT1 interacting protein JBrowse link 6 44,150,875 44,178,378 RGD:14298760
G WWC1 WW and C2 domain containing 1 JBrowse link 16 55,418,391 55,595,202 RGD:9068941
G WWC2 WW and C2 domain containing 2 JBrowse link 15 44,615,731 44,802,717 RGD:14298760
G WWC3 WWC family member 3 JBrowse link X 6,815,648 6,930,939 RGD:14298760
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:14298760
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENO1 enolase 1 JBrowse link 6 69,385,879 69,401,664 RGD:9068941
G HYOU1 hypoxia up-regulated 1 JBrowse link 9 46,264,929 46,277,056 RGD:14298760
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 1 164,381,892 164,469,313 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:14298760
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 5 15,674,028 15,692,944 RGD:14298760
negative regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:14298760
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 13 124,633,906 124,646,237 RGD:14298760
G ASH1L ASH1 like histone lysine methyltransferase JBrowse link 4 94,297,532 94,484,994 RGD:14298760
G CACTIN cactin, spliceosome C complex subunit JBrowse link 2 75,049,250 75,065,990 RGD:14298760
G CASP8 caspase 8 JBrowse link 15 104,923,659 104,948,470 RGD:14298760
G CCDC22 coiled-coil domain containing 22 JBrowse link X 43,285,232 43,303,865 RGD:14298760
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:14298760
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 3 37,883,233 37,919,141 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 1 14,217,032 14,604,906 RGD:14298760
G HDAC1 histone deacetylase 1 JBrowse link 6 88,749,611 88,785,220 RGD:14298760
G IL1RL1 interleukin 1 receptor like 1 JBrowse link 3 51,868,549 51,902,454 RGD:9068941
G LOC100522011 apoptosis-associated speck-like protein containing a CARD JBrowse link 3 17,305,921 17,307,521 RGD:14298760
G LOC100524475 transducin-like enhancer protein 1 JBrowse link 1 234,278,168 234,370,655 RGD:14298760
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G MAPKBP1 mitogen-activated protein kinase binding protein 1 JBrowse link 1 129,533,535 129,589,084 RGD:14298760
G NFKBID NFKB inhibitor delta JBrowse link 6 45,298,289 45,307,471 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 3 38,673,590 38,719,188 RGD:14298760
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 6 56,402,617 56,425,038 RGD:14298760
G NLRP12L NACHT, LRR and PYD domains-containing protein 3 JBrowse link X 88,403,475 88,466,669 RGD:14298760
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 2 90,001 97,441 RGD:9068941
G NLRX1 NLR family member X1 JBrowse link 9 46,384,373 46,400,752 RGD:14298760
G NR1D1 nuclear receptor subfamily 1 group D member 1 JBrowse link 12 22,263,549 22,274,131 RGD:14298760
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 5 83,607,222 83,732,668 RGD:14298760
G OLFM4 olfactomedin 4 JBrowse link 11 26,252,948 26,375,531 RGD:9068941
G OPTN optineurin JBrowse link 10 48,532,029 48,582,952 RGD:9068941
G OTUD7A OTU deubiquitinase 7A JBrowse link 1 143,109,177 143,426,305 RGD:14298760
G OTUD7B OTU deubiquitinase 7B JBrowse link 4 99,054,426 99,111,649 RGD:14298760
G PER1 period circadian regulator 1 JBrowse link 12 53,361,863 53,376,723 RGD:9068941
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A JBrowse link 1 189,248,974 189,296,147 RGD:14298760
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B JBrowse link 3 96,237,660 96,317,278 RGD:14298760
G PPM1N protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) JBrowse link 6 51,865,061 51,871,146 RGD:14298760
G RHOA ras homolog family member A JBrowse link 13 31,918,484 31,991,207 RGD:14298760
G RHOH ras homolog family member H JBrowse link 8 31,321,005 31,372,366 RGD:14298760
G RIOK3 RIO kinase 3 JBrowse link 6 108,338,986 108,363,872 RGD:14298760
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 7 1,841,143 1,880,705 RGD:14298760
G RORA RAR related orphan receptor A JBrowse link 1 110,719,004 111,482,807 RGD:14298760
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G STAT1 signal transducer and activator of transcription 1 JBrowse link 15 95,593,201 95,646,324 RGD:14298760
G TANK TRAF family member associated NFKB activator JBrowse link 15 67,970,972 68,048,681 RGD:9068941
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 1 26,474,158 26,489,771 RGD:14298760
G TNIP1 TNFAIP3 interacting protein 1 JBrowse link 16 71,926,038 71,979,969 RGD:14298760
G TNIP3 TNFAIP3 interacting protein 3 JBrowse link 8 102,892,427 102,990,902 RGD:14298760
G TRIM39 tripartite motif containing 39 JBrowse link 7 23,047,048 23,062,974 RGD:14298760
G TRIM59 tripartite motif containing 59 JBrowse link 13 100,118,824 100,133,117 RGD:14298760
G USP10 ubiquitin specific peptidase 10 JBrowse link 6 3,977,235 4,043,539 RGD:14298760
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 6 93,541,334 93,551,200 RGD:14298760
G ZMYND11 zinc finger MYND-type containing 11 JBrowse link 10 69,159,456 69,295,640 RGD:14298760
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRPA signal regulatory protein alpha JBrowse link 17 33,566,270 33,611,375 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2 BCL2 apoptosis regulator JBrowse link 1 158,337,403 158,518,214 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:14298760
G BCL2L10 BCL2 like 10 JBrowse link 1 119,594,004 119,607,709 RGD:14298760
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 36,988,031 37,005,496 RGD:14298760
G FIGNL1 fidgetin like 1 JBrowse link 9 136,484,217 136,488,262 RGD:14298760
G G2E3 G2/M-phase specific E3 ubiquitin protein ligase JBrowse link 7 68,854,410 68,917,070 RGD:9068941
G GCG glucagon JBrowse link 15 68,800,557 68,810,268 RGD:9068941
G HDAC1 histone deacetylase 1 JBrowse link 6 88,749,611 88,785,220 RGD:14298760
G HDAC2 histone deacetylase 2 JBrowse link 1 79,867,713 79,901,597 RGD:9068941
G HELLS helicase, lymphoid specific JBrowse link 14 105,923,727 105,967,003 RGD:14298760
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 6 18,901,171 18,913,427 RGD:9068941
G IVNS1ABP influenza virus NS1A binding protein JBrowse link 9 126,459,542 126,480,126 RGD:14298760
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 2 16,562,687 16,584,763 RGD:14298760
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 4 98,562,092 98,567,014 RGD:14298760
G MMP9 matrix metallopeptidase 9 JBrowse link 17 48,179,690 48,186,782 RGD:14298760
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 2 58,401,542 58,410,414 RGD:14298760
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 JBrowse link 2 15,031,147 15,036,880 RGD:14298760
G NOC2L NOC2 like nucleolar associated transcriptional repressor JBrowse link 6 63,307,703 63,320,799 RGD:14298760
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 13 130,624,771 130,718,345 RGD:9068941
G PARL presenilin associated rhomboid like JBrowse link 13 121,758,734 121,813,679 RGD:14298760
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:9068941
G PLAUR plasminogen activator, urokinase receptor JBrowse link 6 50,489,773 50,505,453 RGD:14298760
G PPIF peptidylprolyl isomerase F JBrowse link 14 81,674,671 81,681,977 RGD:14298760
G RTKN2 rhotekin 2 JBrowse link 14 65,686,718 65,861,385 RGD:14298760
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 17 40,470,970 40,524,862 RGD:14298760
G URI1 URI1 prefoldin like chaperone JBrowse link 6 40,043,320 40,110,540 RGD:14298760
G VDAC2 voltage dependent anion channel 2 JBrowse link 14 77,767,165 77,782,327 RGD:14298760
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMC10 armadillo repeat containing 10 JBrowse link 9 103,179,754 103,210,658 RGD:9068941
G CEP63 centrosomal protein 63 JBrowse link 13 75,605,622 75,707,087 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 5 33,105,717 33,137,602 RGD:14298760
G MDM4 MDM4 regulator of p53 JBrowse link 9 65,175,488 65,219,747 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:14298760
G PTTG1IP PTTG1 interacting protein JBrowse link 13 207,493,656 207,507,089 RGD:14298760
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 4 34,823,869 34,859,777 RGD:14298760
G RRN3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 3 7,537,131 7,571,990 RGD:14298760
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 4 129,361,596 129,395,790 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACKR3 atypical chemokine receptor 3 JBrowse link 15 136,370,457 136,382,559 RGD:14298760
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 12 42,874,705 42,920,438 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:14298760
G BID BH3 interacting domain death agonist JBrowse link 5 69,849,007 69,874,647 RGD:14298760
G CCAR2 cell cycle and apoptosis regulator 2 JBrowse link 14 6,860,052 6,874,334 RGD:14298760
G CDKN2D cyclin dependent kinase inhibitor 2D JBrowse link 2 69,337,428 69,339,998 RGD:14298760
G CLU clusterin JBrowse link 14 11,336,585 11,352,569 RGD:14298760
G CXCL12 C-X-C motif chemokine ligand 12 JBrowse link 14 91,516,383 91,543,857 RGD:9068941
G DDIAS DNA damage induced apoptosis suppressor JBrowse link 9 17,077,884 17,097,597 RGD:14298760
G SFRP2 secreted frizzled related protein 2 JBrowse link 8 75,337,311 75,345,926 RGD:9068941
G SNAI1 snail family transcriptional repressor 1 JBrowse link 17 51,546,446 51,552,498 RGD:14298760
G SNAI2 snail family transcriptional repressor 2 JBrowse link 4 79,264,880 79,268,475 RGD:14298760
G TMEM161A transmembrane protein 161A JBrowse link 2 58,728,738 58,744,939 RGD:14298760
G TPT1 tumor protein, translationally-controlled 1 JBrowse link 11 21,929,294 21,932,905 RGD:9068941
G TRIM32 tripartite motif containing 32 JBrowse link 1 257,051,421 257,066,911 RGD:14298760
G USP47 ubiquitin specific peptidase 47 JBrowse link 2 47,449,162 47,583,893 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 12 42,874,705 42,920,438 RGD:14298760
G BCL2L12 BCL2 like 12 JBrowse link 6 54,706,453 54,715,127 RGD:14298760
G CD44 CD44 molecule JBrowse link 2 25,788,699 25,884,209 RGD:14298760
G CD74 CD74 molecule JBrowse link 2 151,402,210 151,409,924 RGD:14298760
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 1 127,781,357 127,784,803 RGD:14298760
G KDM1A lysine demethylase 1A JBrowse link 6 80,903,407 80,971,875 RGD:14298760
G MARCHF7 membrane associated ring-CH-type finger 7 JBrowse link 15 66,649,363 66,699,647 RGD:14298760
G MIF macrophage migration inhibitory factor JBrowse link 14 49,840,303 49,841,063 RGD:14298760
G MUC1 mucin 1, cell surface associated JBrowse link 4 94,626,317 94,631,194 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 14 40,411,957 40,415,500 RGD:9068941
G ZNF385A zinc finger protein 385A JBrowse link 5 19,560,317 19,583,254 RGD:14298760
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 11 7,733,874 7,759,528 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:9068941
G TRAP1 TNF receptor associated protein 1 JBrowse link 3 38,536,710 38,595,273 RGD:9068941
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 4 94,026,391 94,082,206 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 7 117,438,622 117,472,005 RGD:9068941
G EPO erythropoietin JBrowse link 3 8,620,508 8,622,936 RGD:14298760
G PTGER2 prostaglandin E receptor 2 JBrowse link 1 181,993,961 182,009,959 RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 9 127,850,164 127,858,866 RGD:14298760
G YBX3 Y-box binding protein 3 JBrowse link 5 61,337,868 61,361,269 RGD:14298760
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BDKRB2 bradykinin receptor B2 JBrowse link 7 117,438,622 117,472,005 RGD:14298760
negative regulation of JNK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIDA axin interactor, dorsalization associated JBrowse link 10 11,430,758 11,466,849 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 RGD:9068941
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 6 49,437,308 49,460,614 RGD:9068941
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 6 34,058,091 34,121,939 RGD:14298760
G DACT1 dishevelled binding antagonist of beta catenin 1 JBrowse link 1 187,719,391 187,729,568 RGD:14298760
G DUSP10 dual specificity phosphatase 10 JBrowse link 10 10,866,446 10,905,852 RGD:14298760
G DUSP19 dual specificity phosphatase 19 JBrowse link 15 88,549,250 88,574,978 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 12 19,336,308 19,349,739 RGD:14298760
G F2RL1 F2R like trypsin receptor 1 JBrowse link 2 85,732,082 85,747,552 RGD:14298760
G FKTN fukutin JBrowse link 1 246,852,387 246,916,650 RGD:9068941
G GPS2 G protein pathway suppressor 2 JBrowse link 12 52,664,869 52,667,643 RGD:14298760
G HDAC3 histone deacetylase 3 JBrowse link 2 143,273,188 143,287,421 RGD:14298760
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 17 37,810,113 37,918,963 RGD:9068941
G KLHL31 kelch like family member 31 JBrowse link 7 27,088,393 27,106,104 RGD:14298760
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 2 16,562,687 16,584,763 RGD:9068941
G MARVELD3 MARVEL domain containing 3 JBrowse link 6 14,616,508 14,630,798 RGD:14298760
G MECOM MDS1 and EVI1 complex locus JBrowse link 13 107,753,207 108,336,136 RGD:14298760
G MEN1 menin 1 JBrowse link 2 7,358,130 7,364,952 RGD:14298760
G NCOR1 nuclear receptor corepressor 1 JBrowse link 12 59,256,868 59,392,564 RGD:9068941
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 JBrowse link 12 48,567,329 48,735,836 RGD:14298760
G PER1 period circadian regulator 1 JBrowse link 12 53,361,863 53,376,723 RGD:9068941
G SFRP4 secreted frizzled related protein 4 JBrowse link 9 108,404,314 108,414,335 RGD:9068941
G SH3RF2 SH3 domain containing ring finger 2 JBrowse link 2 147,290,322 147,413,151 RGD:9068941
G SIRPA signal regulatory protein alpha JBrowse link 17 33,566,270 33,611,375 RGD:9068941
G TAOK3 TAO kinase 3 JBrowse link 14 34,322,016 34,514,234 RGD:14298760
G ZMYND11 zinc finger MYND-type containing 11 JBrowse link 10 69,159,456 69,295,640 RGD:14298760
negative regulation of JUN kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIDA axin interactor, dorsalization associated JBrowse link 10 11,430,758 11,466,849 RGD:14298760
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 10 33,432,529 33,445,556 RGD:14298760
G DUSP10 dual specificity phosphatase 10 JBrowse link 10 10,866,446 10,905,852 RGD:14298760
G DUSP19 dual specificity phosphatase 19 JBrowse link 15 88,549,250 88,574,978 RGD:9068941
G HIPK3 homeodomain interacting protein kinase 3 JBrowse link 2 27,580,125 27,685,926 RGD:14298760
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 2 16,562,687 16,584,763 RGD:9068941
G NPPA natriuretic peptide A JBrowse link 6 71,919,557 71,921,345 RGD:14298760
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 4 106,692,102 106,758,101 RGD:9068941
G SFRP1 secreted frizzled related protein 1 JBrowse link 17 10,436,414 10,489,773 RGD:14298760
G SFRP2 secreted frizzled related protein 2 JBrowse link 8 75,337,311 75,345,926 RGD:14298760
G SFRP5 secreted frizzled related protein 5 JBrowse link 14 109,120,382 109,125,655 RGD:9068941
G TP73 tumor protein p73 JBrowse link 6 65,169,770 65,228,997 RGD:9068941
negative regulation of MAP kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 13 124,633,906 124,646,237 RGD:14298760
G AGT angiotensinogen JBrowse link 14 59,643,030 59,656,835 RGD:14298760
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:14298760
G BMP4 bone morphogenetic protein 4 JBrowse link 1 183,415,989 183,422,888 RGD:14298760
G BMP7 bone morphogenetic protein 7 JBrowse link 17 57,567,770 57,676,516 RGD:9068941
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:9068941
G CAV3 caveolin 3 JBrowse link 13 65,117,868 65,130,886 RGD:14298760
G CBLC Cbl proto-oncogene C JBrowse link 6 51,274,717 51,292,546 RGD:14298760
G CD300A CD300a molecule JBrowse link 12 6,665,578 6,681,329 RGD:9068941
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 JBrowse link 12 24,224,262 24,234,468 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:14298760
G DEFB114 defensin beta 114 JBrowse link 7 43,982,219 43,993,156 RGD:14298760
G DUSP1 dual specificity phosphatase 1 JBrowse link 16 51,457,924 51,461,095 RGD:9068941
G DUSP7 dual specificity phosphatase 7 JBrowse link 13 34,199,404 34,210,621 RGD:9068941
G FEM1A fem-1 homolog A JBrowse link 2 74,041,391 74,045,123 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 4 94,583,905 94,606,689 RGD:14298760
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 84,380,245 84,401,117 RGD:14298760
G HYAL2 hyaluronidase 2 JBrowse link 13 32,805,220 32,813,684 RGD:14298760
G INPP5K inositol polyphosphate-5-phosphatase K JBrowse link 12 47,717,898 47,738,540 RGD:14298760
G INPPL1 inositol polyphosphate phosphatase like 1 JBrowse link 9 6,793,971 6,807,286 RGD:9068941
G IRAK3 interleukin 1 receptor associated kinase 3 JBrowse link 5 30,524,704 30,601,067 RGD:14298760
G KNG1 kininogen 1 JBrowse link 13 124,521,276 124,557,384 RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 4 75,793,273 75,903,710 RGD:14298760
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 12 60,144,138 60,148,743 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 12 43,487,098 43,754,205 RGD:14298760
G NUP62 nucleoporin 62 JBrowse link 6 54,921,627 54,945,705 RGD:14298760
G PAQR3 progestin and adipoQ receptor family member 3 JBrowse link 8 138,646,626 138,670,166 RGD:14298760
G PRKCD protein kinase C delta JBrowse link 13 35,290,835 35,323,245 RGD:14298760
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 17 52,017,100 52,086,747 RGD:14298760
G PTPN5 protein tyrosine phosphatase non-receptor type 5 JBrowse link 2 40,458,865 40,521,470 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 5 63,762,109 63,779,086 RGD:14298760
G PTPRJ protein tyrosine phosphatase receptor type J JBrowse link 2 14,548,489 14,724,823 RGD:14298760
G RGS14 regulator of G protein signaling 14 JBrowse link 2 80,574,411 80,589,998 RGD:14298760
G RGS2 regulator of G protein signaling 2 JBrowse link 10 936,836 940,083 RGD:14298760
G SH2B3 SH2B adaptor protein 3 JBrowse link 14 32,623,286 32,664,606 RGD:14298760
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 9 3,324,091 3,328,493 RGD:14298760
G SORL1 sortilin related receptor 1 JBrowse link 9 48,435,350 48,653,670 RGD:14298760
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 8 100,449,476 100,863,780 RGD:14298760
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 11 52,153,695 52,158,766 RGD:14298760
G SPRY3 sprouty RTK signaling antagonist 3 JBrowse link X 125,744,643 125,764,342 RGD:14298760
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 2 143,877,334 143,891,280 RGD:14298760
G STK38 serine/threonine kinase 38 JBrowse link 7 32,206,532 32,253,673 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 8 32,353,766 32,367,288 RGD:14298760
negative regulation of MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APC APC regulator of WNT signaling pathway JBrowse link 2 116,913,354 116,985,303 RGD:9068941
G ASH1L ASH1 like histone lysine methyltransferase JBrowse link 4 94,297,532 94,484,994 RGD:14298760
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:9068941
G CAV3 caveolin 3 JBrowse link 13 65,117,868 65,130,886 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 13 32,028,019 32,092,450 RGD:14298760
G DUSP1 dual specificity phosphatase 1 JBrowse link 16 51,457,924 51,461,095 RGD:9068941
G DUSP16 dual specificity phosphatase 16 JBrowse link 5 59,869,902 59,961,839 RGD:9068941
G DUSP3 dual specificity phosphatase 3 JBrowse link 12 19,336,308 19,349,739 RGD:9068941
G EFNA1 ephrin A1 JBrowse link 4 94,666,457 94,673,442 RGD:14298760
G IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:9068941
G LEMD2 LEM domain nuclear envelope protein 2 JBrowse link 7 29,980,394 29,997,077 RGD:14298760
G NF1 neurofibromin 1 JBrowse link 12 43,487,098 43,754,205 RGD:9068941
G NF2 neurofibromin 2 JBrowse link 14 46,653,869 46,726,421 RGD:14298760
G NLRP6 NLR family pyrin domain containing 6 JBrowse link 2 90,001 97,441 RGD:9068941
G P2RX7 purinergic receptor P2X 7 JBrowse link 14 31,415,188 31,476,502 RGD:14298760
G PEBP1 phosphatidylethanolamine binding protein 1 JBrowse link 14 34,523,901 34,530,238 RGD:14298760
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 2 59,637,363 59,652,075 RGD:9068941
G PPEF2 protein phosphatase with EF-hand domain 2 JBrowse link 8 71,519,873 71,555,977 RGD:14298760
G PRDM15 PR/SET domain 15 JBrowse link 13 205,174,356 205,241,562 RGD:9068941
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 88,540,261 88,548,593 RGD:14298760
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 5 63,762,109 63,779,086 RGD:9068941
G RNF149 ring finger protein 149 JBrowse link 3 53,032,432 53,067,354 RGD:14298760
G SPRED1 sprouty related EVH1 domain containing 1 JBrowse link 1 132,903,103 133,016,725 RGD:9068941
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1QBP complement C1q binding protein JBrowse link 12 51,548,361 51,553,076 RGD:9068941
G DHX58 DExH-box helicase 58 JBrowse link 12 20,647,698 20,656,691 RGD:14298760
G RIOK3 RIO kinase 3 JBrowse link 6 108,338,986 108,363,872 RGD:14298760
G TKFC triokinase and FMN cyclase JBrowse link 2 10,158,183 10,171,452 RGD:14298760
negative regulation of NIK/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADGRG3 adhesion G protein-coupled receptor G3 JBrowse link 6 19,573,080 19,599,082 RGD:14298760
G ADIPOR1 adiponectin receptor 1 JBrowse link 10 24,907,491 24,923,540 RGD:9068941
G C1QTNF3 C1q and TNF related 3 JBrowse link 16 20,032,973 20,059,905 RGD:9068941
G CAPN1 calpain 1 JBrowse link 2 6,997,513 7,024,410 RGD:9068941
G CCN3 cellular communication network factor 3 JBrowse link 4 19,505,698 19,514,481 RGD:14298760
G CPNE1 copine 1 JBrowse link 17 38,956,489 38,997,189 RGD:9068941
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 6 34,058,091 34,121,939 RGD:14298760
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 36,988,031 37,005,496 RGD:14298760
G FBXW11 F-box and WD repeat domain containing 11 JBrowse link 16 52,212,401 52,337,893 RGD:14298760
G HDAC7 histone deacetylase 7 JBrowse link 5 78,150,554 78,186,051 RGD:9068941
G LITAF lipopolysaccharide induced TNF factor JBrowse link 3 31,482,605 31,576,211 RGD:14298760
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 9 12,486,488 12,492,507 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 3 38,673,590 38,719,188 RGD:14298760
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 6 56,402,617 56,425,038 RGD:14298760
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 2 56,892,241 56,977,412 RGD:14298760
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A JBrowse link 1 189,248,974 189,296,147 RGD:14298760
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B JBrowse link 3 96,237,660 96,317,278 RGD:9068941
G RASSF2 Ras association domain family member 2 JBrowse link 17 13,773,289 13,822,729 RGD:14298760
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 2 6,594,869 6,602,684 RGD:14298760
G TMSB4X thymosin beta 4 X-linked JBrowse link X 9,649,516 9,651,662 RGD:9068941
G TSPAN6 tetraspanin 6 JBrowse link X 82,323,634 82,328,919 RGD:9068941
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats JBrowse link 1 168,353,655 168,453,175 RGD:14298760
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 6 93,541,334 93,551,200 RGD:14298760
negative regulation of nitric oxide mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 9 64,336,354 64,445,669 RGD:14298760
G SPINK1 serine peptidase inhibitor Kazal type 1 JBrowse link 2 149,072,652 149,079,529 RGD:14298760
G THBS1 thrombospondin 1 JBrowse link 1 131,728,781 131,746,098 RGD:14298760
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 10 33,432,529 33,445,556 RGD:14298760
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 1 26,474,158 26,489,771 RGD:14298760
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERBIN erbb2 interacting protein JBrowse link 16 44,415,106 44,533,353 RGD:14298760
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 4 106,692,102 106,758,101 RGD:14298760
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 1 26,474,158 26,489,771 RGD:14298760
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAG5 BAG cochaperone 5 RGD:14298760
G GPX1 glutathione peroxidase 1 JBrowse link 13 31,916,269 31,917,337 RGD:14298760
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 3 10,038,074 10,039,441 RGD:9068941
G MAPK7 mitogen-activated protein kinase 7 JBrowse link 12 60,144,138 60,148,743 RGD:14298760
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 15 82,967,485 83,146,185 RGD:9068941
G NME5 NME/NM23 family member 5 JBrowse link 2 140,132,871 140,168,655 RGD:14298760
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G SOD2 superoxide dismutase 2 JBrowse link 1 7,679,352 7,689,564 RGD:9068941
G VNN1 vanin 1 JBrowse link 1 31,003,338 31,023,731 RGD:14298760
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 1 190,625,436 190,673,926 RGD:14298760
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:14298760
negative regulation of p38MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYLD CYLD lysine 63 deubiquitinase JBrowse link 6 34,058,091 34,121,939 RGD:14298760
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 13 132,819,931 133,084,880 RGD:14298760
G DUSP1 dual specificity phosphatase 1 JBrowse link 16 51,457,924 51,461,095 RGD:14298760
G DUSP10 dual specificity phosphatase 10 JBrowse link 10 10,866,446 10,905,852 RGD:14298760
G EZR ezrin JBrowse link 1 8,403,362 8,452,750 RGD:14298760
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 11 7,733,874 7,759,528 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 4 106,692,102 106,758,101 RGD:14298760
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 7 20,954,229 20,968,390 RGD:14298760
G CRYBA1 crystallin beta A1 JBrowse link 12 45,466,051 45,473,110 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:14298760
G INPP5E inositol polyphosphate-5-phosphatase E RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 1 248,604,817 248,609,574 RGD:9068941
G NCOR1 nuclear receptor corepressor 1 JBrowse link 12 59,256,868 59,392,564 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 3 38,673,590 38,719,188 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 6 53,443,453 53,451,707 RGD:14298760
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 2 51,317,538 51,534,246 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 14 48,040,848 48,051,660 RGD:14298760
G SERPINE2 serpin family E member 2 JBrowse link 15 125,748,383 125,777,788 RGD:14298760
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 12 6,466,138 6,483,539 RGD:14298760
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 3 39,942,366 39,952,824 RGD:9068941
G STAMBP STAM binding protein JBrowse link 3 69,156,012 69,188,256 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:9068941
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 9 88,286,911 88,290,131 RGD:9068941
negative regulation of protein kinase B signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BANK1 B cell scaffold protein with ankyrin repeats 1 JBrowse link 8 118,814,352 119,114,973 RGD:14298760
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 7 20,954,229 20,968,390 RGD:14298760
G CAVIN3 caveolae associated protein 3 JBrowse link 9 3,378,144 3,379,851 RGD:9068941
G CIB1 calcium and integrin binding 1 JBrowse link 7 55,794,834 55,798,666 RGD:14298760
G COPS3 COP9 signalosome subunit 3 JBrowse link 12 61,000,562 61,023,920 RGD:14298760
G CRYBA1 crystallin beta A1 JBrowse link 12 45,466,051 45,473,110 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 13 32,028,019 32,092,450 RGD:14298760
G DDIT3 DNA damage inducible transcript 3 JBrowse link 5 22,785,441 22,789,867 RGD:14298760
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 13 132,819,931 133,084,880 RGD:14298760
G DRD2 dopamine receptor D2 JBrowse link 9 41,068,618 41,135,262 RGD:14298760
G DRD3 dopamine receptor D3 JBrowse link 13 145,769,294 145,817,997 RGD:14298760
G EPHA2 EPH receptor A2 JBrowse link 6 75,251,465 75,279,364 RGD:14298760
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 3 711,427 715,982 RGD:14298760
G HYAL2 hyaluronidase 2 JBrowse link 13 32,805,220 32,813,684 RGD:14298760
G IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:9068941
G INPP5K inositol polyphosphate-5-phosphatase K JBrowse link 12 47,717,898 47,738,540 RGD:14298760
G KLF4 Kruppel like factor 4 JBrowse link 1 248,604,817 248,609,574 RGD:9068941
G LEMD2 LEM domain nuclear envelope protein 2 JBrowse link 7 29,980,394 29,997,077 RGD:14298760
G LMBRD1 LMBR1 domain containing 1 JBrowse link 1 49,869,184 49,977,984 RGD:9068941
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 9 100,846,693 102,171,199 RGD:14298760
G MIR143 microRNA mir-143 JBrowse link 2 150,578,738 150,578,817 RGD:9068941
G MMP3 matrix metallopeptidase 3 JBrowse link 9 33,446,969 33,453,995 RGD:9068941
G MSTN myostatin JBrowse link 15 94,623,526 94,628,440 RGD:14298760
G MTM1 myotubularin 1 JBrowse link X 122,286,904 122,379,302 RGD:14298760
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 6 78,747,687 78,758,821 RGD:14298760
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 6 53,443,453 53,451,707 RGD:14298760
G OTUD3 OTU deubiquitinase 3 JBrowse link 6 78,241,604 78,273,544 RGD:14298760
G PDCD6 programmed cell death 6 JBrowse link 16 79,818,960 79,832,272 RGD:9068941
G PHLDA3 pleckstrin homology like domain family A member 3 JBrowse link 10 23,824,181 23,827,428 RGD:9068941
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 1 158,642,810 158,863,643 RGD:14298760
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 7 45,447,354 45,925,141 RGD:14298760
G PLEKHA1 pleckstrin homology domain containing A1 JBrowse link 14 131,960,932 132,016,664 RGD:14298760
G POU5F1 POU class 5 homeobox 1 JBrowse link 7 23,564,654 23,570,691 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 14 99,929,590 100,021,619 RGD:9068941
G PTPRJ protein tyrosine phosphatase receptor type J JBrowse link 2 14,548,489 14,724,823 RGD:14298760
G RACK1 receptor for activated C kinase 1 JBrowse link 2 57,280,192 57,284,846 RGD:14298760
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 1 271,494,243 271,624,609 RGD:14298760
G SFRP5 secreted frizzled related protein 5 JBrowse link 14 109,120,382 109,125,655 RGD:14298760
G SH2B3 SH2B adaptor protein 3 JBrowse link 14 32,623,286 32,664,606 RGD:14298760
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G SLA-8 MHC class I antigen 8 JBrowse link 7 23,622,352 23,625,818 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 12 6,466,138 6,483,539 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:9068941
G XDH xanthine dehydrogenase JBrowse link 3 107,987,060 108,052,043 RGD:14298760
negative regulation of protein kinase C signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGKD diacylglycerol kinase delta JBrowse link 15 133,749,349 133,867,804 RGD:9068941
G DGKG diacylglycerol kinase gamma JBrowse link 13 123,956,294 124,182,966 RGD:9068941
G GPD1L glycerol-3-phosphate dehydrogenase 1 like JBrowse link 13 18,126,471 18,176,669 RGD:9068941
G MYADM myeloid associated differentiation marker JBrowse link 6 56,236,306 56,278,577 RGD:9068941
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 1 158,642,810 158,863,643 RGD:9068941
negative regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 2 143,304,076 143,327,588 RGD:9068941
G ARHGAP24 Rho GTPase activating protein 24 JBrowse link 8 132,761,967 133,506,065 RGD:14298760
G ARHGAP44 Rho GTPase activating protein 44 JBrowse link 12 57,049,900 57,206,706 RGD:14298760
G NF1 neurofibromin 1 JBrowse link 12 43,487,098 43,754,205 RGD:14298760
G STMN3 stathmin 3 JBrowse link 17 62,600,450 62,609,851 RGD:9068941
negative regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:9068941
G DGKZ diacylglycerol kinase zeta JBrowse link 2 16,134,046 16,176,043 RGD:9068941
G EPHB2 EPH receptor B2 JBrowse link 6 80,649,098 80,849,979 RGD:14298760
G FBP1 fructose-bisphosphatase 1 JBrowse link 10 27,588,609 27,622,225 RGD:14298760
G LZTR1 leucine zipper like transcription regulator 1 JBrowse link 14 50,576,413 50,590,397 RGD:14298760
G MAPKAP1 MAPK associated protein 1 JBrowse link 1 266,096,192 266,346,384 RGD:14298760
G MFN2 mitofusin 2 JBrowse link 6 72,026,512 72,056,439 RGD:14298760
G NF1 neurofibromin 1 JBrowse link 12 43,487,098 43,754,205 RGD:9068941
G NUP62 nucleoporin 62 JBrowse link 6 54,921,627 54,945,705 RGD:14298760
G PPP2CB protein phosphatase 2 catalytic subunit beta JBrowse link 15 54,295,786 54,325,220 RGD:9068941
G RABGEF1 RAB guanine nucleotide exchange factor 1 JBrowse link 3 16,308,112 16,376,604 RGD:9068941
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 1 271,494,243 271,624,609 RGD:14298760
G RASA1 RAS p21 protein activator 1 JBrowse link 2 94,879,615 94,992,725 RGD:14298760
G RASA2 RAS p21 protein activator 2 JBrowse link 13 82,230,138 82,352,759 RGD:14298760
G RASA3 RAS p21 protein activator 3 JBrowse link 11 78,951,017 79,027,991 RGD:14298760
G RASA4B RAS p21 protein activator 4B JBrowse link 3 9,816,576 9,846,340 RGD:14298760
G RASAL1 RAS protein activator like 1 JBrowse link 14 38,598,901 38,633,190 RGD:14298760
G RASAL3 RAS protein activator like 3 JBrowse link 2 62,142,368 62,153,812 RGD:14298760
G SPRY1 sprouty RTK signaling antagonist 1 JBrowse link 8 100,449,476 100,863,780 RGD:14298760
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 11 52,153,695 52,158,766 RGD:14298760
G SPRY3 sprouty RTK signaling antagonist 3 JBrowse link X 125,744,643 125,764,342 RGD:14298760
G SPRY4 sprouty RTK signaling antagonist 4 JBrowse link 2 143,877,334 143,891,280 RGD:14298760
G STAMBP STAM binding protein JBrowse link 3 69,156,012 69,188,256 RGD:14298760
G SYNGAP1 synaptic Ras GTPase activating protein 1 JBrowse link 7 29,723,745 29,752,351 RGD:14298760
G TGFB2 transforming growth factor beta 2 JBrowse link 10 8,306,136 8,435,307 RGD:9068941
G TIMP2 TIMP metallopeptidase inhibitor 2 JBrowse link 12 3,254,794 3,300,835 RGD:9068941
G TNK1 tyrosine kinase non receptor 1 JBrowse link 12 52,711,133 52,719,101 RGD:14298760
G TRIM67 tripartite motif containing 67 JBrowse link 14 59,260,070 59,303,244 RGD:14298760
negative regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 9 120,888,891 120,984,724 RGD:9068941
G ADRA1A adrenoceptor alpha 1A JBrowse link 14 10,623,391 10,733,378 RGD:9068941
G ADRA1B adrenoceptor alpha 1B JBrowse link 16 63,550,123 64,010,838 RGD:9068941
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 2 143,304,076 143,327,588 RGD:9068941
G ARHGAP35 Rho GTPase activating protein 35 JBrowse link 6 52,711,463 52,841,295 RGD:14298760
G ARHGAP42 Rho GTPase activating protein 42 JBrowse link 9 31,720,586 31,999,730 RGD:14298760
G BCL6 BCL6 transcription repressor JBrowse link 13 125,377,247 125,401,328 RGD:14298760
G CCDC125 coiled-coil domain containing 125 JBrowse link 16 47,442,080 47,478,589 RGD:14298760
G COPS3 COP9 signalosome subunit 3 JBrowse link 12 61,000,562 61,023,920 RGD:14298760
G CUL3 cullin 3 JBrowse link 15 126,191,605 126,287,148 RGD:14298760
G DLC1 DLC1 Rho GTPase activating protein JBrowse link 17 1,169,709 1,637,171 RGD:14298760
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G HEG1 heart development protein with EGF like domains 1 JBrowse link 13 135,268,566 135,358,673 RGD:9068941
G ITGA3 integrin subunit alpha 3 JBrowse link 12 26,234,769 26,269,327 RGD:14298760
G ITGB1 integrin subunit beta 1 JBrowse link 10 56,078,393 56,130,608 RGD:14298760
G KANK1 KN motif and ankyrin repeat domains 1 JBrowse link 1 221,015,042 221,218,875 RGD:14298760
G KCTD10 potassium channel tetramerization domain containing 10 JBrowse link 14 41,442,628 41,470,215 RGD:14298760
G KCTD13 potassium channel tetramerization domain containing 13 JBrowse link 3 18,124,628 18,141,589 RGD:14298760
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 18 29,426,044 29,541,526 RGD:14298760
G MYOC myocilin JBrowse link 9 114,087,370 114,098,765 RGD:14298760
G RASIP1 Ras interacting protein 1 JBrowse link 6 54,058,748 54,072,415 RGD:14298760
G RIPOR1 RHO family interacting cell polarization regulator 1 JBrowse link 6 28,156,508 28,183,640 RGD:9068941
G RIPOR2 RHO family interacting cell polarization regulator 2 JBrowse link 7 19,609,358 19,842,345 RGD:14298760
G SCAI suppressor of cancer cell invasion JBrowse link 1 265,710,644 265,867,099 RGD:14298760
G STMN1 stathmin 1 JBrowse link 6 83,356,404 83,362,546 RGD:9068941
G TNFAIP1 TNF alpha induced protein 1 JBrowse link 12 44,616,840 44,626,330 RGD:14298760
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1QBP complement C1q binding protein JBrowse link 12 51,548,361 51,553,076 RGD:9068941
G DHX58 DExH-box helicase 58 JBrowse link 12 20,647,698 20,656,691 RGD:14298760
G GPATCH3 G-patch domain containing 3 JBrowse link 6 84,200,727 84,218,710 RGD:14298760
G NLRX1 NLR family member X1 JBrowse link 9 46,384,373 46,400,752 RGD:14298760
G NPLOC4 NPL4 homolog, ubiquitin recognition factor JBrowse link 12 1,251,377 1,285,668 RGD:14298760
G RNF125 ring finger protein 125 JBrowse link 6 115,857,697 115,905,550 RGD:9068941
G SEC14L1 SEC14 like lipid binding 1 JBrowse link 12 4,439,045 4,489,078 RGD:14298760
G UFD1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 14 51,113,858 51,132,820 RGD:14298760
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALM1 calmodulin 1 JBrowse link 7 112,160,823 112,171,754 RGD:9068941
G CALM2 calmodulin 2 JBrowse link 3 93,371,765 93,386,378 RGD:9068941
G CALM3 calmodulin 3 JBrowse link 6 52,506,979 52,516,704 RGD:9068941
G CASQ2 calsequestrin 2 JBrowse link 4 104,918,204 104,984,019 RGD:14298760
G CLIC2 chloride intracellular channel 2 JBrowse link X 125,546,451 125,560,059 RGD:14298760
G FKBP1A FKBP prolyl isomerase 1A JBrowse link 17 33,910,047 33,935,212 RGD:9068941
G FKBP1B FKBP prolyl isomerase 1B JBrowse link 3 114,623,529 114,636,200 RGD:14298760
G GSTO1 glutathione S-transferase omega 1 JBrowse link 14 115,206,434 115,216,624 RGD:9068941
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 8 131,002,973 131,058,932 RGD:14298760
G SRI sorcin JBrowse link 9 68,492,235 68,515,247 RGD:14298760
negative regulation of signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ELL3 elongation factor for RNA polymerase II 3 JBrowse link 1 127,781,357 127,784,803 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 5 33,105,717 33,137,602 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 6 53,443,453 53,451,707 RGD:14298760
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 12 40,075,259 40,151,034 RGD:9068941
G RNF34 ring finger protein 34 JBrowse link 14 31,202,030 31,229,529 RGD:14298760
G SENP2 SUMO specific peptidase 2 JBrowse link 13 123,429,915 123,469,913 RGD:9068941
negative regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGAP12 Rho GTPase activating protein 12 JBrowse link 10 42,458,115 42,577,351 RGD:14298760
G ARHGAP25 Rho GTPase activating protein 25 JBrowse link 3 73,556,561 73,649,997 RGD:14298760
G CD2AP CD2 associated protein JBrowse link 7 42,218,016 42,332,523 RGD:9068941
G CGNL1 cingulin like 1 JBrowse link 1 114,424,148 114,628,331 RGD:14298760
G CYRIB CYFIP related Rac1 interactor B JBrowse link 4 10,476,137 10,643,395 RGD:9068941
G SH3BP1 SH3 domain binding protein 1 JBrowse link 5 10,172,303 10,187,883 RGD:9068941
G SLIT2 slit guidance ligand 2 JBrowse link 8 14,758,426 15,149,515 RGD:14298760
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP10 dual specificity phosphatase 10 JBrowse link 10 10,866,446 10,905,852 RGD:9068941
G FOXM1 forkhead box M1 JBrowse link 5 67,246,219 67,263,215 RGD:14298760
G FOXO1 forkhead box O1 JBrowse link 11 15,317,222 15,410,059 RGD:14298760
G IGBP1 immunoglobulin binding protein 1 JBrowse link X 56,173,773 56,206,121 RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 4 12,455,141 12,460,360 RGD:14298760
G PBK PDZ binding kinase JBrowse link 14 11,543,657 11,577,286 RGD:14298760
G QARS1 glutaminyl-tRNA synthetase 1 JBrowse link 13 31,715,686 31,723,200 RGD:14298760
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1S1 AKT1 substrate 1 JBrowse link 6 54,881,581 54,890,917 RGD:14298760
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 2 45,895,637 46,025,174 RGD:14298760
G COPS3 COP9 signalosome subunit 3 JBrowse link 12 61,000,562 61,023,920 RGD:14298760
G CRYBA1 crystallin beta A1 JBrowse link 12 45,466,051 45,473,110 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 14 75,117,708 75,119,907 RGD:14298760
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 48,421,788 48,523,530 RGD:14298760
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 4 18,969,509 19,180,131 RGD:14298760
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 1 19,806,363 19,893,350 RGD:9068941
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 2 133,958,112 134,093,408 RGD:9068941
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 6 49,690,319 49,700,735 RGD:14298760
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 1 190,625,436 190,673,926 RGD:14298760
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 14 39,852,537 39,885,898 RGD:9068941
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 7 48,501,067 48,539,300 RGD:14298760
G MTM1 myotubularin 1 JBrowse link X 122,286,904 122,379,302 RGD:14298760
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 13 32,830,895 32,834,205 RGD:9068941
G NPRL3 NPR3 like, GATOR1 complex subunit JBrowse link 3 41,478,465 41,540,719 RGD:14298760
G PDCD6 programmed cell death 6 JBrowse link 16 79,818,960 79,832,272 RGD:9068941
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 16 25,745,902 25,783,524 RGD:14298760
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 6 155,683,392 155,754,283 RGD:14298760
G SH3BP4 SH3 domain binding protein 4 JBrowse link 15 135,003,501 135,094,801 RGD:14298760
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G TBC1D7 TBC1 domain family member 7 JBrowse link 7 9,685,273 9,708,781 RGD:14298760
G TMEM127 transmembrane protein 127 JBrowse link 3 46,966,858 47,017,659 RGD:14298760
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 2 74,203,753 74,220,811 RGD:14298760
G TSC1 TSC complex subunit 1 JBrowse link 1 272,636,530 272,685,948 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:14298760
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 1 128,319,311 128,474,330 RGD:14298760
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 7 37,655,808 37,785,301 RGD:14298760
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 9 36,620,656 36,759,555 RGD:14298760
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 18 32,798,278 32,900,769 RGD:14298760
G C5H12orf66 chromosome 5 C12orf66 homolog JBrowse link 5 28,656,227 28,679,095 RGD:14298760
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 14 47,261,905 47,266,729 RGD:14298760
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 3 11,956,289 12,039,913 RGD:9068941
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 48,421,788 48,523,530 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 2 133,958,112 134,093,408 RGD:14298760
G FNIP2 folliculin interacting protein 2 JBrowse link 8 47,702,877 47,838,541 RGD:14298760
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 5 67,292,901 67,306,208 RGD:9068941
G KPTN kaptin, actin binding protein JBrowse link 6 53,238,650 53,246,458 RGD:14298760
G RNF152 ring finger protein 152 JBrowse link 1 159,529,879 159,606,031 RGD:14298760
G SESN1 sestrin 1 JBrowse link 1 75,056,731 75,170,374 RGD:14298760
G SESN2 sestrin 2 JBrowse link 6 85,321,982 85,348,044 RGD:14298760
G SESN3 sestrin 3 JBrowse link 9 27,207,239 27,279,205 RGD:14298760
G STK11 serine/threonine kinase 11 JBrowse link 2 77,229,888 77,249,322 RGD:14298760
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 6 167,811,589 167,861,321 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:9068941
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TSPAN6 tetraspanin 6 JBrowse link X 82,323,634 82,328,919 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    cellular process 15624
      signal transduction 5871
        negative regulation of signal transduction 1190
          negative regulation of intracellular signal transduction 526
            negative regulation of I-kappaB kinase/NF-kappaB signaling + 48
            negative regulation of MAPK cascade + 177
            negative regulation of NIK/NF-kappaB signaling 23
            negative regulation of TOR signaling + 44
            negative regulation of cAMP-mediated signaling + 29
            negative regulation of cGMP-mediated signaling 6
            negative regulation of calcium-mediated signaling + 31
            negative regulation of hippo signaling 11
            negative regulation of intrinsic apoptotic signaling pathway + 97
            negative regulation of mitotic spindle assembly checkpoint signaling 0
            negative regulation of nitric oxide mediated signal transduction 3
            negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
            negative regulation of phosphatidylinositol 3-kinase signaling 16
            negative regulation of phosphorelay signal transduction system + 0
            negative regulation of protein kinase B signaling 45
            negative regulation of protein kinase C signaling 5
            negative regulation of protein kinase D signaling 0
            negative regulation of signal transduction by p53 class mediator + 33
            negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint 0
            negative regulation of small GTPase mediated signal transduction + 65
            negative regulation of stress-activated protein kinase signaling cascade + 45
            negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 16411
    biological regulation 11882
      regulation of biological process 11314
        regulation of cellular process 10867
          signal transduction 5871
            regulation of signal transduction 2820
              negative regulation of signal transduction 1190
                negative regulation of intracellular signal transduction 526
                  negative regulation of I-kappaB kinase/NF-kappaB signaling + 48
                  negative regulation of MAPK cascade + 177
                  negative regulation of NIK/NF-kappaB signaling 23
                  negative regulation of TOR signaling + 44
                  negative regulation of cAMP-mediated signaling + 29
                  negative regulation of cGMP-mediated signaling 6
                  negative regulation of calcium-mediated signaling + 31
                  negative regulation of hippo signaling 11
                  negative regulation of intrinsic apoptotic signaling pathway + 97
                  negative regulation of mitotic spindle assembly checkpoint signaling 0
                  negative regulation of nitric oxide mediated signal transduction 3
                  negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
                  negative regulation of phosphatidylinositol 3-kinase signaling 16
                  negative regulation of phosphorelay signal transduction system + 0
                  negative regulation of protein kinase B signaling 45
                  negative regulation of protein kinase C signaling 5
                  negative regulation of protein kinase D signaling 0
                  negative regulation of signal transduction by p53 class mediator + 33
                  negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint 0
                  negative regulation of small GTPase mediated signal transduction + 65
                  negative regulation of stress-activated protein kinase signaling cascade + 45
                  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.