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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of activation of Janus kinase activity
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Accession:GO:1902569 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity.
Synonyms:narrow_synonym: down regulation of activation of JAK1 kinase activity;   down regulation of activation of JAK1 protein;   down regulation of activation of JAK2 kinase activity;   down regulation of activation of JAK2 protein;   down regulation of tyrosine phosphorylation of JAK1 protein;   downregulation of activation of JAK1 kinase activity;   downregulation of activation of JAK1 protein;   downregulation of activation of JAK2 kinase activity;   downregulation of tyrosine phosphorylation of JAK1 protein;   inhibition of activation of JAK1 kinase activity;   inhibition of activation of JAK1 protein;   inhibition of activation of JAK2 kinase activity;   inhibition of activation of JAK2 protein;   inhibition of tyrosine phosphorylation of JAK1 protein;   negative regulation of activation of JAK1 protein;   negative regulation of activation of JAK2 kinase activity;   negative regulation of activation of JAK2 protein;   negative regulation of tyrosine phosphorylation of JAK1 protein
 related_synonym: down regulation of tyrosine phosphorylation of JAK2 protein;   downregulation of tyrosine phosphorylation of JAK2 protein;   inhibition of tyrosine phosphorylation of JAK2 protein;   negative regulation of tyrosine phosphorylation of JAK2 protein


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negative regulation of activation of Janus kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1625011

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Term Annotations click to browse term
  biological_process 19332
    cellular process 17237
      signal transduction 6871
        regulation of signal transduction 2885
          regulation of receptor signaling pathway via STAT 163
            regulation of receptor signaling pathway via JAK-STAT 158
              regulation of activation of Janus kinase activity 8
                negative regulation of activation of Janus kinase activity 2
Path 2
Term Annotations click to browse term
  biological_process 19332
    biological regulation 13335
      regulation of biological process 12650
        regulation of metabolic process 6536
          regulation of cellular metabolic process 6024
            regulation of phosphorus metabolic process 1854
              regulation of phosphate metabolic process 1853
                regulation of phosphorylation 1656
                  regulation of kinase activity 868
                    regulation of protein kinase activity 758
                      positive regulation of protein kinase activity 502
                        activation of protein kinase activity 289
                          activation of Janus kinase activity 17
                            regulation of activation of Janus kinase activity 8
                              negative regulation of activation of Janus kinase activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.