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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of nuclear cell cycle DNA replication
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Accession:GO:1902576 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.
Synonyms:exact_synonym: down regulation of DNA replication involved in S phase;   down regulation of nuclear cell cycle DNA replication;   downregulation of DNA replication involved in S phase;   downregulation of nuclear cell cycle DNA replication;   negative regulation of DNA replication involved in S phase
 narrow_synonym: inhibition of DNA replication involved in S phase;   inhibition of nuclear cell cycle DNA replication
 related_synonym: down regulation of DNA replication during S phase;   downregulation of DNA replication during S phase;   inhibition of DNA replication during S phase;   negative regulation of DNA replication during S phase


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signal transduction involved in intra-S DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek2 checkpoint kinase 2 ISO (PMID:11298456) RGD PMID:11298456 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cell cycle process 1204
        negative regulation of cell cycle process 226
          negative regulation of nuclear cell cycle DNA replication 1
            negative regulation of initiation of premeiotic DNA replication 0
            negative regulation of mitotic cell cycle DNA replication + 1
            negative regulation of telomere maintenance via semi-conservative replication 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          macromolecule biosynthetic process 5161
            cellular macromolecule biosynthetic process 5074
              DNA replication 256
                DNA-dependent DNA replication 151
                  cell cycle DNA replication 42
                    nuclear DNA replication 37
                      regulation of nuclear cell cycle DNA replication 14
                        negative regulation of nuclear cell cycle DNA replication 1
                          negative regulation of initiation of premeiotic DNA replication 0
                          negative regulation of mitotic cell cycle DNA replication + 1
                          negative regulation of telomere maintenance via semi-conservative replication 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.