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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cell cycle G1/S phase transition
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Accession:GO:1902808 term browser browse the term
Definition:Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
Synonyms:exact_synonym: up regulation of cell cycle G1/S phase transition;   upregulation of cell cycle G1/S phase transition
 narrow_synonym: activation of cell cycle G1/S phase transition


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positive regulation of cell cycle G1/S phase transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 ISO
IEA
ISS
(PMID:15923622)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15923622 GO_REF:0000024, GO_REF:0000107 NCBI chr13:60,403,771...60,496,511
Ensembl chr13:60,403,771...60,496,511
JBrowse link
G Crnn cornulin ISO
IBA
(PMID:30009832)
PMID:21873635
RGD PMID:30009832, PMID:21873635 RGD:13792537 NCBI chr 2:193,427,097...193,432,070
Ensembl chr 2:193,429,176...193,431,487
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (PMID:18713946) RGD PMID:18713946 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fam83d family with sequence similarity 83, member D ISO
IBA
(PMID:25646692)
PMID:21873635
RGD PMID:25646692, PMID:21873635 RGD:13792537 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Gli1 GLI family zinc finger 1 ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO
ISS
(PMID:15923622)
GO_REF:0000024
RGD
UniProt
PMID:15923622 GO_REF:0000024 NCBI chr 1:85,362,421...85,367,999
Ensembl chr 1:85,362,268...85,368,031
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 ISO
IBA
(PMID:19039327)
PMID:21873635
RGD PMID:19039327, PMID:21873635 RGD:13792537 NCBI chr 1:198,448,790...198,451,078
Ensembl chr 1:198,449,040...198,450,688
JBrowse link
G Phb2 prohibitin 2 ISO (PMID:23548868) RGD PMID:23548868 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Stxbp4 syntaxin binding protein 4 ISO (PMID:19451233) RGD PMID:19451233 NCBI chr10:78,005,745...78,168,641
Ensembl chr10:78,009,338...78,168,609
JBrowse link
G Tp63 tumor protein p63 ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO
IEA
(PMID:18483258)
GO_REF:0000107
RGD
Ensembl
PMID:18483258 GO_REF:0000107 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEA
ISO
GO_REF:0000107
RNAcentral:URS00003A19A3_9606 (PMID:28890348)
Ensembl
RGD
PMID:28890348 GO_REF:0000107 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Aif1 allograft inflammatory factor 1 ISS
ISO
GO_REF:0000024
(PMID:11557666), (PMID:15117732), (PMID:19745784)
UniProt
RGD
PMID:11557666, PMID:15117732, PMID:19745784 GO_REF:0000024 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:18483258) RGD PMID:18483258 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ankrd17 ankyrin repeat domain 17 ISO (PMID:19150984) RGD PMID:19150984 NCBI chr14:19,291,025...19,431,521
Ensembl chr14:19,318,565...19,431,515
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B IMP RGD PMID:11162633 RGD:633716 NCBI chr 5:62,070,709...62,094,633
Ensembl chr 5:62,071,346...62,094,633
JBrowse link
G Anxa1 annexin A1 ISO
IBA
MGI:MGI:2449710 (MGI:MGI:2661244|PMID:12553880)
PMID:21873635
RGD PMID:12553880, PMID:21873635 MGI:MGI:2661244, RGD:13792537 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IMP RGD PMID:12730053 RGD:2315680 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Ccnd1 cyclin D1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 ISO
IBA
(PMID:24130168)
PMID:21873635
RGD PMID:24130168, PMID:21873635 RGD:13792537 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Cdc45 cell division cycle 45 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Crebbp CREB binding protein IMP RGD PMID:18496732 RGD:2316124 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Cul4a cullin 4A ISO (MGI:MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:MGI:3820325 NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654
JBrowse link
G Cul4b cullin 4B ISO (MGI:MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:MGI:3820325 NCBI chr  X:124,831,391...124,870,329
Ensembl chr  X:124,832,628...124,870,329
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA RGD PMID:14742689 RGD:2306669 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:20837705) RGD PMID:20837705 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Egfr epidermal growth factor receptor ISO (PMID:18483258) RGD PMID:18483258 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 ISO (PMID:18426977) RGD PMID:18426977 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Fgf10 fibroblast growth factor 10 ISO (PMID:17188682) RGD PMID:17188682 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Hyal1 hyaluronidase 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21829529)
Ensembl
UniProt
RGD
PMID:21829529 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:116,332,834...116,337,522
Ensembl chr 8:116,332,796...116,335,435
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IDA RGD PMID:18230363 RGD:7242757 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kmt2e lysine methyltransferase 2E ISO (PMID:23629655) RGD PMID:23629655 NCBI chr 4:8,187,751...8,255,578
Ensembl chr 4:8,187,751...8,255,514
JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator ISO (MGI:MGI:5461251|PMID:23154982) RGD PMID:23154982 MGI:MGI:5461251 NCBI chr 2:231,866,888...231,882,002
Ensembl chr 2:231,867,135...231,881,939
JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated ISO (PMID:16914750) RGD PMID:16914750 NCBI chr 5:144,106,339...144,108,703
Ensembl chr 5:144,106,802...144,108,708
JBrowse link
G Lsm11 LSM11, U7 small nuclear RNA associated ISO (PMID:16914750) RGD PMID:16914750 NCBI chr10:31,023,561...31,041,700
Ensembl chr10:31,028,697...31,041,626
JBrowse link
G Mepce methylphosphate capping enzyme ISO (MGI:MGI:5461251|PMID:23154982) RGD PMID:23154982 MGI:MGI:5461251 NCBI chr12:21,721,246...21,725,965
Ensembl chr12:21,721,837...21,725,435
JBrowse link
G Plcb1 phospholipase C beta 1 ISO
ISS
(MGI:MGI:4942262|PMID:10913438)
GO_REF:0000024
RGD
BHF-UCL
PMID:10913438 GO_REF:0000024, MGI:MGI:4942262 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Plrg1 pleiotropic regulator 1 ISO MGI:MGI:3848230 (MGI:MGI:3847829|PMID:19307306) RGD PMID:19307306 MGI:MGI:3847829 NCBI chr 2:182,040,338...182,056,669
Ensembl chr 2:182,040,318...182,056,673
JBrowse link
G Rdx radixin ISO (MGI:MGI:5645204|PMID:21047789) RGD PMID:21047789 MGI:MGI:5645204 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G Rgcc regulator of cell cycle ISO (PMID:19162005) RGD PMID:19162005 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Rpl17 ribosomal protein L17 IMP RGD PMID:23065385 RGD:11035308 NCBI chr18:70,969,733...70,972,839
Ensembl chr18:70,970,596...70,975,494
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 ISO (PMID:18426977) RGD PMID:18426977 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691
JBrowse link
G Tert telomerase reverse transcriptase IMP RGD PMID:24376652 RGD:11038675 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfdp1 transcription factor Dp-1 ISO (PMID:17062573) RGD PMID:17062573 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 ISO UniProtKB:P38936 (PMID:21628527) RGD PMID:21628527 NCBI chr15:7,402,210...7,928,320
Ensembl chr15:7,871,497...7,927,939
JBrowse link
traversing start control point of mitotic cell cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mdm2 MDM2 proto-oncogene ISO (MGI:MGI:2661697|PMID:10906133) RGD PMID:10906133 MGI:MGI:2661697 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mtbp MDM2 binding protein ISO
IBA
(MGI:MGI:2661697|PMID:10906133)
PMID:21873635
RGD PMID:10906133, PMID:21873635 MGI:MGI:2661697, RGD:13792537 NCBI chr 7:95,309,928...95,392,418
Ensembl chr 7:95,309,928...95,387,680
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cell cycle process 1210
        cell cycle phase transition 431
          cell cycle G1/S phase transition 204
            positive regulation of cell cycle G1/S phase transition 48
              positive regulation of G1/S transition of mitotic cell cycle + 38
Path 2
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of biological process 13075
        regulation of cellular process 12561
          regulation of cell cycle 1021
            regulation of cell cycle process 623
              positive regulation of cell cycle process 275
                positive regulation of cell cycle phase transition 102
                  positive regulation of cell cycle G1/S phase transition 48
                    positive regulation of G1/S transition of mitotic cell cycle + 38
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.