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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic DNA replication
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Accession:GO:1902969 term browser browse the term
Definition:Any nuclear DNA replication that is involved in a mitotic cell cycle.
Synonyms:exact_synonym: DNA replication involved in S phase involved in mitotic cell cycle;   mitotic cell cycle DNA replication;   mitotic nuclear cell cycle DNA replication
 related_synonym: DNA replication during S phase involved in mitotic cell cycle;   nuclear cell cycle DNA replication involved in mitotic cell cycle


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mitotic DNA replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm6 minichromosome maintenance complex component 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
DNA strand elongation involved in mitotic DNA replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins1 GINS complex subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:146,695,366...146,716,787
Ensembl chr 3:146,695,344...146,716,816
JBrowse link
mitotic DNA replication initiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm2 minichromosome maintenance complex component 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:8,973,861...9,039,616
Ensembl chr 5:8,978,010...9,038,594
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
mitotic DNA replication preinitiation complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
mitotic DNA replication termination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtfdc1 replication termination factor 2 domain containing 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:170,443,895...170,473,456
Ensembl chr 3:170,443,855...170,473,456
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO
IEA
(PMID:21076401)
GO_REF:0000107
RGD
Ensembl
PMID:21076401 GO_REF:0000107 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Rad51 RAD51 recombinase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
Okazaki fragment processing involved in mitotic DNA replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig1 DNA ligase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:75,356,212...75,394,757
Ensembl chr 1:75,356,220...75,394,758
JBrowse link
G LOC100911727 DNA ligase 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:75,224,143...75,264,441
Ensembl chr 1:75,233,703...75,264,293
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 ISO
IEA
(MGI:MGI:79015|PMID:2161540)
GO_REF:0000107
RGD
Ensembl
PMID:2161540 GO_REF:0000107, MGI:MGI:79015 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 ISO MGI:MGI:2180033 (MGI:MGI:3583382|PMID:15980864) RGD PMID:15980864 MGI:MGI:3583382 NCBI chr 5:139,982,404...140,015,541
Ensembl chr 5:139,983,680...140,015,541
JBrowse link
signal transduction involved in intra-S DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek2 checkpoint kinase 2 ISO (PMID:11298456) RGD PMID:11298456 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell cycle process 1210
        mitotic cell cycle process 694
          mitotic DNA replication 16
            DNA strand elongation involved in mitotic DNA replication + 1
            DNA synthesis involved in mitotic DNA replication 0
            Okazaki fragment processing involved in mitotic DNA replication 2
            mitotic DNA replication DNA duplex unwinding 0
            mitotic DNA replication DNA ligation 0
            mitotic DNA replication initiation + 5
            mitotic DNA replication maintenance of fidelity + 2
            mitotic DNA replication preinitiation complex assembly 1
            mitotic DNA replication termination 1
            mitotic DNA-dependent DNA replication 0
            mitotic pre-replicative complex assembly 0
            negative regulation of mitotic cell cycle DNA replication + 1
            positive regulation of mitotic cell cycle DNA replication + 1
            regulation of mitotic cell cycle DNA replication + 3
            removal of RNA primer involved in mitotic DNA replication 0
            synthesis of RNA primer involved in mitotic DNA replication 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          macromolecule biosynthetic process 5159
            cellular macromolecule biosynthetic process 5074
              DNA replication 257
                DNA-dependent DNA replication 154
                  cell cycle DNA replication 42
                    nuclear DNA replication 37
                      mitotic DNA replication 16
                        DNA strand elongation involved in mitotic DNA replication + 1
                        DNA synthesis involved in mitotic DNA replication 0
                        Okazaki fragment processing involved in mitotic DNA replication 2
                        mitotic DNA replication DNA duplex unwinding 0
                        mitotic DNA replication DNA ligation 0
                        mitotic DNA replication initiation + 5
                        mitotic DNA replication maintenance of fidelity + 2
                        mitotic DNA replication preinitiation complex assembly 1
                        mitotic DNA replication termination 1
                        mitotic DNA-dependent DNA replication 0
                        mitotic pre-replicative complex assembly 0
                        negative regulation of mitotic cell cycle DNA replication + 1
                        positive regulation of mitotic cell cycle DNA replication + 1
                        regulation of mitotic cell cycle DNA replication + 3
                        removal of RNA primer involved in mitotic DNA replication 0
                        synthesis of RNA primer involved in mitotic DNA replication 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.