Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of proteolysis involved in cellular protein catabolic process
go back to main search page
Accession:GO:1903051 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
Comment:Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).
Synonyms:exact_synonym: down regulation of peptidolysis involved in cellular protein catabolic process;   down regulation of peptidolysis involved in cellular protein catabolism;   down regulation of proteolysis involved in cellular protein catabolic process;   downregulation of peptidolysis involved in cellular protein catabolic process;   downregulation of peptidolysis involved in cellular protein catabolism;   downregulation of proteolysis involved in cellular protein catabolic process;   negative regulation of peptidolysis involved in cellular protein catabolic process;   negative regulation of peptidolysis involved in cellular protein catabolism
 narrow_synonym: inhibition of peptidolysis involved in cellular protein catabolic process;   inhibition of peptidolysis involved in cellular protein catabolism;   inhibition of proteolysis involved in cellular protein catabolic process
 related_synonym: down regulation of peptidolysis during cellular protein catabolic process;   down regulation of peptidolysis during cellular protein catabolism;   down regulation of proteolysis during cellular protein catabolic process;   down regulation of proteolysis during cellular protein catabolism;   downregulation of peptidolysis during cellular protein catabolic process;   downregulation of peptidolysis during cellular protein catabolism;   downregulation of proteolysis during cellular protein catabolic process;   downregulation of proteolysis during cellular protein catabolism;   inhibition of peptidolysis during cellular protein catabolic process;   inhibition of peptidolysis during cellular protein catabolism;   inhibition of proteolysis during cellular protein catabolic process;   inhibition of proteolysis during cellular protein catabolism;   negative regulation of peptidolysis during cellular protein catabolic process;   negative regulation of peptidolysis during cellular protein catabolism;   negative regulation of proteolysis during cellular protein catabolic process;   negative regulation of proteolysis during cellular protein catabolism


show annotations for term's descendants           Sort by:
 
negative regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (PMID:25217637)
(MGI:5468878|PMID:23277542)
ParkinsonsUK-UCL
MGI
PMID:23277542, PMID:25217637 MGI:5468878 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G EFNA1 ephrin A1 ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 1:130,475,128...130,482,531
Ensembl chr 1:134,083,855...134,091,228
JBrowse link
G EPHA4 EPH receptor A4 ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790
JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440
JBrowse link
G SVIP small VCP interacting protein ISO (PMID:17872946) UniProtKB PMID:17872946 NCBI chr11:22,828,321...22,837,536
Ensembl chr11:22,735,361...22,744,558
JBrowse link
G USP14 ubiquitin specific peptidase 14 ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chr18:14,104,754...14,158,402
Ensembl chr18:17,745,733...17,797,070
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 ISO (MGI:3813160|PMID:18606867) UniProt PMID:18606867 MGI:3813160 NCBI chr11:72,653,721...72,673,698
Ensembl chr11:76,295,778...76,315,292
JBrowse link
G UBXN1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404
JBrowse link
G USP25 ubiquitin specific peptidase 25 ISO (PMID:22590560) ParkinsonsUK-UCL PMID:22590560 NCBI chr21:2,468,993...2,618,200
Ensembl chr21:15,724,729...15,982,182
JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase ISO (PMID:8175643) CAFA PMID:8175643 NCBI chr 9:84,488,339...84,503,360
Ensembl chr 9:112,859,171...112,873,784
JBrowse link
G F8A1 coagulation factor VIII associated 1 ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:144,366,123...144,367,842 JBrowse link
G F8A2 coagulation factor VIII associated 2 ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:144,851,466...144,853,185 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 ISO (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr16:56,135,482...56,147,046
Ensembl chr16:75,483,459...75,495,019
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO PMID:17517623
(MGI:6148636|PMID:17517623)
ARUK-UCL PMID:17517623 MGI:6148636, RGD:13514081 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872
JBrowse link
G LAMP3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr 3:180,152,363...180,193,223
Ensembl chr 3:188,324,660...188,363,268
JBrowse link
G LOC100988585 transmembrane protein 220 ISO (MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:5643882 NCBI chr17:40,923,397...40,973,382
Ensembl chr17:45,703,642...45,720,520
Ensembl chr17:45,703,642...45,720,520
JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chr2B:47,004,211...47,059,901
Ensembl chr2B:164,377,605...164,432,907
JBrowse link
G OPHN1 oligophrenin 1 ISO (MGI:5303043|PMID:21874017) UniProt PMID:21874017 MGI:5303043 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114
JBrowse link
G PRKCG protein kinase C gamma ISO (MGI:5467682|PMID:23185022) UniProt PMID:23185022 MGI:5467682 NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977
JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 ISO (PMID:29934401) UniProt PMID:29934401 NCBI chr16:37,430,698...37,464,089
Ensembl chr16:56,563,353...56,596,619
JBrowse link
G PSMF1 proteasome inhibitor subunit 1 ISO (PMID:10764772) UniProtKB PMID:10764772 NCBI chr20:1,275,662...1,325,410
Ensembl chr20:1,043,513...1,092,237
JBrowse link
G USP19 ubiquitin specific peptidase 19 ISO (MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:5614537 NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112
JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 ISO (PMID:24475098) ParkinsonsUK-UCL PMID:24475098 NCBI chr14:84,182,879...84,189,180
Ensembl chr14:103,997,524...103,998,927
JBrowse link
G BAG6 BAG cochaperone 6 ISO (MGI:3808636|PMID:18678708) UniProt PMID:18678708 MGI:3808636 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321
JBrowse link
G CAMLG calcium modulating ligand ISO (PMID:20553626) UniProt PMID:20553626 NCBI chr 5:130,138,644...130,144,540
Ensembl chr 5:136,282,910...136,295,382
JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 ISO (PMID:23398316) UniProtKB PMID:23398316 NCBI chr 8:21,854,803...21,870,556
Ensembl chr 8:18,794,027...18,808,571
JBrowse link
G CLEC16A C-type lectin domain containing 16A ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512
JBrowse link
G DDRGK1 DDRGK domain containing 1 ISO (PMID:28263186) UniProtKB PMID:28263186 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789
JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H ISO (PMID:32269044) FlyBase PMID:32269044 NCBI chr 8:113,320,059...113,440,769
Ensembl chr 8:115,863,490...115,973,872
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO (PMID:15313915) UniProtKB PMID:15313915 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 ISO (MGI:3807767|PMID:11546783) BHF-UCL PMID:11546783 MGI:3807767 NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO (PMID:24613385)
(PMID:16280321)
UniProtKB
MGI
PMID:16280321, PMID:24613385 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872
JBrowse link
G KLHL40 kelch like family member 40 ISO (MGI:5586592|PMID:24960163) MGI PMID:24960163 MGI:5586592 NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055
JBrowse link
G MAP1A microtubule associated protein 1A ISO (MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:5703671 NCBI chr15:22,472,641...22,493,293
Ensembl chr15:40,627,099...40,647,752
JBrowse link
G MTM1 myotubularin 1 ISO (MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:5510937 NCBI chr  X:140,218,742...140,323,495
Ensembl chr  X:150,174,758...150,255,381
JBrowse link
G N4BP1 NEDD4 binding protein 1 ISO (MGI:3829128|PMID:17592138) UniProt PMID:17592138 MGI:3829128 NCBI chr16:28,809,881...28,881,352
Ensembl chr16:47,698,353...47,769,755
JBrowse link
G NOP53 NOP53 ribosome biogenesis factor ISO (PMID:22522597) UniProtKB PMID:22522597 NCBI chr19:44,739,739...44,751,303 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO (PMID:26678539) UniProtKB PMID:26678539 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PANO1 proapoptotic nucleolar protein 1 ISO (PMID:22094112) UniProtKB PMID:22094112 NCBI chr11:814,040...816,633 JBrowse link
G PARK7 Parkinsonism associated deglycase ISO (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271
JBrowse link
G PBK PDZ binding kinase ISO (MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:5293269 NCBI chr 8:27,084,789...27,112,986
Ensembl chr 8:24,285,395...24,313,658
JBrowse link
G RPL11 ribosomal protein L11 ISO (MGI:5897550|PMID:21804542) UniProt PMID:21804542 MGI:5897550 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313
JBrowse link
G RYBP RING1 and YY1 binding protein ISO (PMID:27060496) UniProtKB PMID:27060496 NCBI chr 3:72,315,494...72,389,328
Ensembl chr 3:74,247,807...74,318,398
JBrowse link
G SDCBP syndecan binding protein ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833
JBrowse link
G SENP1 SUMO specific peptidase 1 ISO (MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:3818351 NCBI chr12:40,624,200...40,689,837
Ensembl chr12:41,507,348...41,558,969
JBrowse link
G SHH sonic hedgehog signaling molecule ISO (MGI:3624046|PMID:16611981) MGI PMID:16611981 MGI:3624046 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651
JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 ISO (MGI:5310666|PMID:22285184) MGI PMID:22285184 MGI:5310666 NCBI chr 3:47,487,948...47,683,623
Ensembl chr 3:48,590,221...48,781,248
JBrowse link
G TAF9 TATA-box binding protein associated factor 9 ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 5:44,630,503...44,635,760 JBrowse link
G TLK2 tousled like kinase 2 ISO (PMID:20016786) UniProtKB PMID:20016786 NCBI chr17:56,542,670...56,678,294
Ensembl chr17:61,689,998...61,830,394
JBrowse link
G TRIM39 tripartite motif containing 39 ISO (PMID:23213251) UniProt PMID:23213251 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 ISO (MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:6362140 NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928
JBrowse link
G UBXN1 UBX domain protein 1 ISO (PMID:20351172) UniProtKB PMID:20351172 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404
JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 ISO (PMID:23770237) UniProtKB PMID:23770237 NCBI chr 1:168,471,501...168,519,366
Ensembl chr 1:172,764,606...172,811,880
JBrowse link
G USP7 ubiquitin specific peptidase 7 ISO (PMID:26678539) UniProtKB PMID:26678539 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146
JBrowse link
G WAC WW domain containing adaptor with coiled-coil ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr10:28,685,294...28,777,176
Ensembl chr10:29,042,331...29,130,591
JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STYX serine/threonine/tyrosine interacting protein ISO (PMID:28007894) UniProtKB PMID:28007894 NCBI chr14:33,326,587...33,371,399
Ensembl chr14:51,610,523...51,651,096
JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A ISO (MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:4461099 NCBI chr 6:34,450,695...34,653,881
Ensembl chr 6:35,548,124...35,776,185
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (PMID:16173922), (PMID:18560357)
(MGI:5468878|PMID:23277542)
CAFA
MGI
PMID:16173922, PMID:18560357, PMID:23277542 MGI:5468878 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr20:689,494...752,092
Ensembl chr20:456,629...521,126
JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr16:38,426,399...38,466,575
Ensembl chr16:57,557,270...57,596,218
JBrowse link
G HFE homeostatic iron regulator ISO (PMID:24904118) BHF-UCL PMID:24904118 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 ISO (PMID:21628596) FlyBase PMID:21628596 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G PDCL3 phosducin like 3 ISO (PMID:23792958) MGI PMID:23792958
G PML PML nuclear body scaffold ISO (PMID:15195100) UniProtKB PMID:15195100 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G PSEN1 presenilin 1 ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
G QRICH2 glutamine rich 2 ISO (PMID:30683861)
(MGI:6277293|PMID:30683861)
UniProt PMID:30683861 MGI:6277293 NCBI chr17:70,222,033...70,256,747
Ensembl chr17:75,774,651...75,807,651
JBrowse link
G RPL11 ribosomal protein L11 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313
JBrowse link
G RPL23 ribosomal protein L23 ISO (PMID:15314173) CAFA PMID:15314173 NCBI chr17:18,417,964...18,421,708
Ensembl chr17:18,690,682...18,698,253
JBrowse link
G RPL5 ribosomal protein L5 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522
JBrowse link
G RPS7 ribosomal protein S7 ISO (PMID:17310983) CAFA PMID:17310983 NCBI chr2A:3,593,350...3,599,106 JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472
JBrowse link
G TAF1 TATA-box binding protein associated factor 1 ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323
JBrowse link
G TRIM39 tripartite motif containing 39 ISO (PMID:19100260) BHF-UCL PMID:19100260 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764
JBrowse link
G WNT1 Wnt family member 1 ISO (MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:3628833 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    metabolic process 7977
      primary metabolic process 7049
        protein metabolic process 4008
          proteolysis 1112
            negative regulation of proteolysis 225
              negative regulation of proteolysis involved in cellular protein catabolic process 70
                negative regulation of proteasomal protein catabolic process + 51
                negative regulation of proteolysis associated with antigen processing and presentation 0
                negative regulation of ubiquitin-dependent protein catabolic process + 54
Path 2
Term Annotations click to browse term
  biological_process 12566
    biological regulation 9172
      regulation of biological process 8675
        regulation of metabolic process 5279
          regulation of macromolecule metabolic process 4855
            regulation of protein metabolic process 2374
              regulation of protein catabolic process 363
                negative regulation of protein catabolic process 126
                  negative regulation of cellular protein catabolic process 83
                    negative regulation of proteolysis involved in cellular protein catabolic process 70
                      negative regulation of proteasomal protein catabolic process + 51
                      negative regulation of proteolysis associated with antigen processing and presentation 0
                      negative regulation of ubiquitin-dependent protein catabolic process + 54
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.