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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of proteolysis involved in cellular protein catabolic process
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Accession:GO:1903052 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
Comment:overexpression of cathepsin C propeptide significantly increased the degradation of of intestinal alkaline phosphatase (IAP)
Synonyms:exact_synonym: positive regulation of peptidolysis involved in cellular protein catabolic process;   positive regulation of peptidolysis involved in cellular protein catabolism;   up regulation of peptidolysis involved in cellular protein catabolic process;   up regulation of peptidolysis involved in cellular protein catabolism;   up regulation of proteolysis involved in cellular protein catabolic process;   upregulation of peptidolysis involved in cellular protein catabolic process;   upregulation of peptidolysis involved in cellular protein catabolism;   upregulation of proteolysis involved in cellular protein catabolic process
 narrow_synonym: activation of peptidolysis involved in cellular protein catabolic process;   activation of peptidolysis involved in cellular protein catabolism;   activation of proteolysis involved in cellular protein catabolic process
 related_synonym: activation of peptidolysis during cellular protein catabolic process;   activation of peptidolysis during cellular protein catabolism;   activation of proteolysis during cellular protein catabolic process;   activation of proteolysis during cellular protein catabolism;   positive regulation of peptidolysis during cellular protein catabolic process;   positive regulation of peptidolysis during cellular protein catabolism;   positive regulation of proteolysis during cellular protein catabolic process;   positive regulation of proteolysis during cellular protein catabolism;   up regulation of peptidolysis during cellular protein catabolic process;   up regulation of peptidolysis during cellular protein catabolism;   up regulation of proteolysis during cellular protein catabolic process;   up regulation of proteolysis during cellular protein catabolism;   upregulation of peptidolysis during cellular protein catabolic process;   upregulation of peptidolysis during cellular protein catabolism;   upregulation of proteolysis during cellular protein catabolic process;   upregulation of proteolysis during cellular protein catabolism


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positive regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Ctsc cathepsin C IDA PMID:18307834 ParkinsonsUK-UCL PMID:18307834 RGD:8661625 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Gba glucosylceramidase beta ISO (PMID:21700325)
(MGI:5141165|PMID:21700325)
RGD PMID:21700325 MGI:5141165 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Rgn regucalcin IDA RGD PMID:1513338 RGD:9590188 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613
JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcap31 B-cell receptor-associated protein 31 ISO UniProtKB:Q9BUN8 (PMID:18555783) RGD PMID:18555783 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
(PMID:24089527)
Ensembl
RGD
PMID:24089527 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 ISS
ISO
PMID:22045699
(PMID:18307982), (PMID:22045699)
RGD PMID:18307982, PMID:22045699, PMID:22045699 RGD:10047316 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23246001) RGD PMID:23246001 NCBI chr 7:11,521,949...11,538,691
Ensembl chr 7:11,521,998...11,539,319
JBrowse link
G Ubqln1 ubiquilin 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18307982)
Ensembl
UniProt
RGD
PMID:18307982 GO_REF:0000024, GO_REF:0000107 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
G Ubqln2 ubiquilin 2 ISO (PMID:18307982) RGD PMID:18307982 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 ISO (PMID:17000876) RGD PMID:17000876 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bag6 BAG cochaperone 6 ISO (PMID:24424410) RGD PMID:24424410 NCBI chr20:5,124,512...5,138,084
Ensembl chr20:5,125,349...5,138,084
JBrowse link
G Rnf185 ring finger protein 185 ISS
ISO
GO_REF:0000024
(PMID:27485036)
UniProt
RGD
PMID:27485036 GO_REF:0000024 NCBI chr14:83,648,400...83,685,273
Ensembl chr14:83,648,402...83,685,273
JBrowse link
G Rnft1 ring finger protein, transmembrane 1 ISO (PMID:27485036) RGD PMID:27485036 NCBI chr10:73,807,455...73,821,178
Ensembl chr10:73,809,157...73,817,982
JBrowse link
G Tmem259 transmembrane protein 259 IBA
ISO
PMID:21873635
(MGI:5648655|PMID:25977983)
RGD PMID:25977983, PMID:21873635 MGI:5648655, RGD:13792537 NCBI chr 7:12,771,239...12,777,901
Ensembl chr 7:12,771,227...12,779,862
JBrowse link
G Tmem67 transmembrane protein 67 IMP RGD PMID:19815549 RGD:8554391 NCBI chr 5:25,666,138...25,721,056
Ensembl chr 5:25,666,137...25,721,072
JBrowse link
G Usp13 ubiquitin specific peptidase 13 ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:119,197,153...119,317,507
Ensembl chr 2:119,197,239...119,317,500
JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag2 BAG cochaperone 2 ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118
JBrowse link
G Dab2ip DAB2 interacting protein IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20080667)
Ensembl
UniProt
RGD
PMID:20080667 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Ddrgk1 DDRGK domain containing 1 ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator ISO
IBA
(PMID:19416853)
PMID:21873635
RGD PMID:19416853, PMID:21873635 RGD:13792537 NCBI chr18:28,507,167...28,516,567
Ensembl chr18:28,506,934...28,516,209
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Fmr1 FMRP translational regulator 1 ISS
ISO
GO_REF:0000024
(MGI:5770038|PMID:24709664)
UniProt
RGD
PMID:24709664 GO_REF:0000024, MGI:5770038 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO (PMID:22180649) RGD PMID:22180649 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator ISO
ISS
(PMID:16300740)
GO_REF:0000024
RGD
UniProt
PMID:16300740 GO_REF:0000024 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Osbpl7 oxysterol binding protein-like 7 ISO (PMID:21669198) RGD PMID:21669198 NCBI chr10:84,986,330...85,003,947
Ensembl chr10:84,986,328...85,004,562
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:124,123,283...124,135,644
Ensembl chr 6:124,123,228...124,135,658
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581
JBrowse link
G Rnf40 ring finger protein 40 IDA RGD PMID:12121982 RGD:633892 NCBI chr 1:199,037,472...199,052,823
Ensembl chr 1:199,037,544...199,052,172
JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 ISO (PMID:21603654) RGD PMID:21603654 NCBI chr 7:40,171,957...40,217,056
Ensembl chr 7:40,171,963...40,217,056
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 ISO (MGI:6150565|PMID:29518356) RGD PMID:29518356 MGI:6150565 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
G Xbp1 X-box binding protein 1 ISO (MGI:4946566|PMID:21317886) RGD PMID:21317886 MGI:4946566 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:3589701|PMID:15937334) RGD PMID:15937334 MGI:3589701 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:27,473,477...27,597,206
Ensembl chr 4:27,473,477...27,597,206
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,166,359...64,268,555
Ensembl chr 8:64,166,360...64,268,555
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:117,387,004...117,446,085
Ensembl chr 8:117,387,010...117,446,019
JBrowse link
G Atg7 autophagy related 7 ISO MGI:2446434|MGI:3587769|MGI:3691571 (MGI:5465208|PMID:23152632) RGD PMID:23152632 MGI:5465208 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Aurka aurora kinase A IEA
ISO
GO_REF:0000107
(MGI:3697244|PMID:17060449)
Ensembl
RGD
PMID:17060449 GO_REF:0000107, MGI:3697244 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Axin1 axin 1 ISO (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833
G Bag2 BAG cochaperone 2 NOT ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118
JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 ISO UniProtKB:Q99496 (PMID:22302990) RGD PMID:22302990 NCBI chr 2:123,283,402...123,322,991
Ensembl chr 2:123,283,388...123,323,170
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 ISO (PMID:25974097) RGD PMID:25974097 NCBI chr19:55,438,409...55,510,652
Ensembl chr19:55,441,572...55,510,460
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains ISO (MGI:5310666|PMID:22285184) RGD PMID:22285184 MGI:5310666 NCBI chr12:52,562,594...52,596,162
Ensembl chr12:52,562,597...52,596,076
JBrowse link
G Clu clusterin IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:20068069)
Ensembl
UniProt
RGD
PMID:20068069, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cop1 COP1, E3 ubiquitin ligase ISO (PMID:19805145) RGD PMID:19805145 NCBI chr13:76,942,883...77,076,015
Ensembl chr13:76,942,928...77,075,723
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 IEA
ISO
GO_REF:0000107
(PMID:11955436), (PMID:19364825)
Ensembl
RGD
PMID:11955436, PMID:19364825 GO_REF:0000107 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
JBrowse link
G Csnk1d casein kinase 1, delta ISS
ISO
IBA
GO_REF:0000024
(MGI:3849793|PMID:19414593)
PMID:21873635
UniProt
RGD
PMID:19414593, PMID:21873635 GO_REF:0000024, MGI:3849793, RGD:13792537 NCBI chr10:110,147,786...110,182,413
Ensembl chr10:110,148,600...110,182,408
JBrowse link
G Csnk1e casein kinase 1, epsilon IBA
ISO
PMID:21873635
(MGI:3849793|PMID:19414593)
RGD PMID:19414593, PMID:21873635 MGI:3849793, RGD:13792537 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359
JBrowse link
G Dab2 DAB adaptor protein 2 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dda1 DET1 and DDB1 associated 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:19,877,873...19,885,501
Ensembl chr16:19,881,122...19,885,500
JBrowse link
G Ddrgk1 DDRGK domain containing 1 ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase ISO UniProtKB:Q8NHY2 (PMID:14739464) RGD PMID:14739464 NCBI chr 1:140,519,755...140,535,969
Ensembl chr 1:140,519,702...140,535,934
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 ISO
IBA
(PMID:15936278)
PMID:21873635
RGD PMID:15936278, PMID:21873635 RGD:13792537 NCBI chr 9:82,436,453...82,444,669
Ensembl chr 9:82,436,458...82,444,668
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Fbxo22 F-box protein 22 IBA
ISO
PMID:21873635
(MGI:3840749|PMID:19319192)
RGD PMID:19319192, PMID:21873635 MGI:3840749, RGD:13792537 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Gba glucosylceramidase beta ISO (MGI:5501380|PMID:23707074) RGD PMID:23707074 MGI:5501380 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO MGI:2387010 (MGI:3695876|PMID:17189825) RGD PMID:17189825 MGI:3695876 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO (PMID:25897075) RGD PMID:25897075 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEA
ISO
GO_REF:0000107
MGI:1924375|MGI:3039600 (MGI:5437589|PMID:22660580)
(PMID:19364825), (PMID:25897075)
Ensembl
RGD
PMID:19364825, PMID:22660580, PMID:25897075 GO_REF:0000107, MGI:5437589 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO
IBA
(PMID:24613385)
PMID:21873635
RGD PMID:24613385, PMID:21873635 RGD:13792537 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO
IBA
(PMID:24613385)
PMID:21873635
RGD PMID:24613385, PMID:21873635 RGD:13792537 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 ISO (PMID:16831871) RGD PMID:16831871 NCBI chr 1:72,732,418...72,756,087
Ensembl chr 1:72,732,668...72,756,082
JBrowse link
G Il33 interleukin 33 IEA
ISO
GO_REF:0000107
MGI:1861437|MGI:3039600 (MGI:5437589|PMID:22660580)
Ensembl
RGD
PMID:22660580 GO_REF:0000107, MGI:5437589 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Klhl40 kelch-like family member 40 ISO (MGI:5700633|PMID:25940086) RGD PMID:25940086 MGI:5700633 NCBI chr 8:130,416,265...130,421,871
Ensembl chr 8:130,416,355...130,421,871
JBrowse link
G LOC108348108 heat shock 70 kDa protein 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:2,699,707...2,701,856
Ensembl chr20:4,877,324...4,879,779
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (MGI:4454597|PMID:20457918) RGD PMID:20457918 MGI:4454597 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO (PMID:11278372) RGD PMID:11278372 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 1:32,054,390...32,085,416
Ensembl chr 1:32,058,044...32,084,877
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)
RGD PMID:21804542, PMID:25818168, PMID:27323397 MGI:5897550 NCBI chr 1:77,836,522...77,843,991
Ensembl chr 1:77,836,196...77,844,189
JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 ISO (PMID:16707496) RGD PMID:16707496 NCBI chr 4:6,950,870...6,981,400
Ensembl chr 4:6,951,478...6,978,073
JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 ISS
ISO
GO_REF:0000024
(PMID:27588481)
UniProt
RGD
PMID:27588481 GO_REF:0000024 NCBI chr 1:242,372,458...242,373,764
Ensembl chr 1:242,372,458...242,373,764
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 ISO (MGI:5487503|PMID:22406621) RGD PMID:22406621 MGI:5487503 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Plk1 polo-like kinase 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19473992)
Ensembl
UniProt
RGD
PMID:19473992 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 ISO
IEA
(PMID:17030191)
GO_REF:0000107
RGD
Ensembl
PMID:17030191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IBA
ISO
PMID:21873635
(MGI:5543313|PMID:23858059)
RGD PMID:23858059, PMID:21873635 MGI:5543313, RGD:13792537 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Psen1 presenilin 1 ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psen2 presenilin 2 ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 ISO
IEA
ISS
(PMID:16023600)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16023600 GO_REF:0000024, GO_REF:0000107 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO
ISS
(PMID:19785988)
GO_REF:0000024
RGD
UniProt
PMID:19785988 GO_REF:0000024 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein ISO (PMID:26296656) RGD PMID:26296656 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rbx1 ring-box 1 ISO UniProtKB:Q7L5Y6 (PMID:14739464) RGD PMID:14739464 NCBI chr 7:122,700,849...122,710,907
Ensembl chr 7:122,700,854...122,709,935
JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 ISO (PMID:19483087) RGD PMID:19483087 NCBI chr14:17,615,968...17,631,715
Ensembl chr14:17,615,968...17,631,714
JBrowse link
G Rnf14 ring finger protein 14 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:31,443,424...31,468,641
Ensembl chr18:31,444,472...31,468,640
JBrowse link
G Rnf144a ring finger protein 144A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:45,509,895...45,629,233
Ensembl chr 6:45,509,787...45,629,168
JBrowse link
G Rnf144b ring finger protein 144B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:17,817,122...17,947,777
Ensembl chr17:17,817,100...17,947,777
JBrowse link
G Rnf180 ring finger protein 180 IBA
ISO
PMID:21873635
(MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250)
RGD PMID:18363970, PMID:23926250, PMID:21873635 MGI:3819024, MGI:5505713, RGD:13792537 NCBI chr 2:35,718,100...35,892,578
Ensembl chr 2:35,718,889...35,870,578
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:75,058,758...75,098,331
Ensembl chr 7:75,058,758...75,098,331
JBrowse link
G Rnf19b ring finger protein 19B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:147,246,032...147,270,892
Ensembl chr 5:147,246,037...147,270,957
JBrowse link
G Rnf217 ring finger protein 217 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:28,301,960...28,391,582
Ensembl chr 1:28,301,922...28,390,837
JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 IMP
ISO
PMID:22128169
(PMID:22128169)
RGD PMID:22128169, PMID:22128169 RGD:13673844 NCBI chr18:36,371,041...36,471,020
Ensembl chr18:36,371,041...36,471,015
JBrowse link
G Sirt2 sirtuin 2 ISS
ISO
GO_REF:0000024
(MGI:5574427|PMID:24681946)
UniProt
RGD
PMID:24681946 GO_REF:0000024, MGI:5574427 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Smad7 SMAD family member 7 ISO
IEA
(PMID:11278251)
GO_REF:0000107
RGD
Ensembl
PMID:11278251 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Socs5 suppressor of cytokine signaling 5 ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 ISO (PMID:11146632) RGD PMID:11146632 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 ISO (PMID:18408734) RGD PMID:18408734 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 ISO (PMID:18408734) RGD PMID:18408734 NCBI chr10:104,085,401...104,097,983
Ensembl chr10:104,086,002...104,097,812
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 ISO (PMID:15053879) RGD PMID:15053879 NCBI chr  X:71,412,291...71,486,456
Ensembl chr  X:71,412,289...71,485,085
JBrowse link
G Trib1 tribbles pseudokinase 1 IBA
ISO
PMID:21873635
(MGI:4457446|PMID:20410507)
RGD PMID:20410507, PMID:21873635 MGI:4457446, RGD:13792537 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Trib2 tribbles pseudokinase 2 IBA
ISO
PMID:21873635
(MGI:4457446|PMID:20410507)
RGD PMID:20410507, PMID:21873635 MGI:4457446, RGD:13792537 NCBI chr 6:41,016,722...41,040,972
Ensembl chr 6:41,016,730...41,039,437
JBrowse link
G Trib3 tribbles pseudokinase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 IMP RGD PMID:12750002 RGD:1299567 NCBI chr11:89,557,273...89,591,175
Ensembl chr11:89,557,273...89,591,175
JBrowse link
G Usp5 ubiquitin specific peptidase 5 ISO (PMID:19098288) RGD PMID:19098288 NCBI chr 4:157,332,735...157,347,803
Ensembl chr 4:157,332,740...157,347,803
JBrowse link
G Vcp valosin-containing protein ISO (PMID:9452483) RGD PMID:9452483 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Zer1 zyg-11 related, cell cycle regulator ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 3:8,662,579...8,690,486
Ensembl chr 3:8,662,579...8,690,305
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A ISO MGI:3664591 (MGI:3663213|PMID:16973439) RGD PMID:16973439 MGI:3663213 NCBI chr12:17,252,093...17,263,477
Ensembl chr12:17,252,093...17,263,477
JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 5:127,844,062...127,878,792
Ensembl chr 5:127,847,129...127,878,792
JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 ISO
ISS
(PMID:20889502)
GO_REF:0000024
RGD
UniProt
PMID:20889502 GO_REF:0000024 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Sirt2 sirtuin 2 IEA
ISO
ISS
GO_REF:0000107
(PMID:24681946)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24681946 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
positive regulation of transcription factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw8 F-box and WD repeat domain containing 8 ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr12:44,046,204...44,138,138
Ensembl chr12:44,046,217...44,138,138
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA
ISO
GO_REF:0000107
(MGI:6148490|PMID:29153991)
Ensembl
RGD
PMID:29153991 GO_REF:0000107, MGI:6148490 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Sirt6 sirtuin 6 ISO (PMID:27457971) RGD PMID:27457971 NCBI chr 7:10,937,622...10,943,048
Ensembl chr 7:10,937,599...10,943,063
JBrowse link
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agbl4 ATP/GTP binding protein-like 4 ISO MGI:5788002 (MGI:6149282|PMID:29593216) RGD PMID:29593216 MGI:6149282 NCBI chr 5:130,742,297...131,656,581
NCBI chr 5:130,286,393...130,305,884
Ensembl chr 5:131,380,297...131,455,211
Ensembl chr 5:131,380,297...131,455,211
JBrowse link
G Agtpbp1 ATP/GTP binding protein 1 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:5,510,009...5,614,416
Ensembl chr17:5,511,385...5,614,435
JBrowse link
G Axin1 axin 1 IDA
ISO
PMID:10228155
(MGI:3628833|PMID:16601693)
RGD PMID:16601693, PMID:10228155 MGI:3628833, RGD:8553327
G Ccdc22 coiled-coil domain containing 22 ISO
IBA
(PMID:23563313)
PMID:21873635
RGD PMID:23563313, PMID:21873635 RGD:13792537 NCBI chr  X:15,742,978...15,754,925
Ensembl chr  X:15,742,978...15,754,925
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 NOT ISO
ISS
(PMID:16173922)
GO_REF:0000024
RGD
UniProt
PMID:16173922 GO_REF:0000024 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832
JBrowse link
G Clu clusterin ISO
IBA
ISS
(PMID:20068069)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20068069, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Disc1 DISC1 scaffold protein ISO (MGI:4837265|PMID:20880836) RGD PMID:20880836 MGI:4837265 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Egf epidermal growth factor ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Fbxo22 F-box protein 22 ISO (MGI:3840749|PMID:19319192) RGD PMID:19319192 MGI:3840749 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISS
ISO
GO_REF:0000024
(MGI:6282935|PMID:27238018)
(PMID:20208556), (PMID:27238018)
UniProt
RGD
PMID:20208556, PMID:27238018 GO_REF:0000024, MGI:6282935 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 ISO (MGI:3803048|PMID:18619870) RGD PMID:18619870 MGI:3803048 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719
JBrowse link
G Pten phosphatase and tensin homolog ISO (PMID:21241890) RGD PMID:21241890 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptk2 protein tyrosine kinase 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:5306293|PMID:18206965)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18206965 GO_REF:0000024, GO_REF:0000107, MGI:5306293 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISS
ISO
GO_REF:0000024
(MGI:4453113|PMID:19880522)
UniProt
RGD
PMID:19880522 GO_REF:0000024, MGI:4453113 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Rnf139 ring finger protein 139 ISO (PMID:25239945) RGD PMID:25239945 NCBI chr 7:98,770,840...98,782,025
Ensembl chr 7:98,770,840...98,782,025
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO (PMID:21454619) RGD PMID:21454619 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 ISO (MGI:3813414|PMID:18644859) RGD PMID:18644859 MGI:3813414 NCBI chr20:11,726,488...11,737,050
Ensembl chr20:11,726,497...11,737,050
JBrowse link
G Trim67 tripartite motif-containing 67 ISO (MGI:5427306|PMID:22337885) RGD PMID:22337885 MGI:5427306 NCBI chr19:57,554,665...57,593,401
Ensembl chr19:57,556,694...57,592,722
JBrowse link
G Vcp valosin-containing protein IMP RGD PMID:16103111 RGD:1599730 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      primary metabolic process 10900
        protein metabolic process 6221
          proteolysis 1893
            positive regulation of proteolysis 376
              positive regulation of proteolysis involved in cellular protein catabolic process 126
                positive regulation of proteasomal protein catabolic process + 109
                positive regulation of proteolysis associated with antigen processing and presentation 0
                positive regulation of ubiquitin-dependent protein catabolic process + 103
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of metabolic process 6993
          regulation of macromolecule metabolic process 6498
            regulation of protein metabolic process 2956
              regulation of protein catabolic process 398
                positive regulation of protein catabolic process 225
                  positive regulation of cellular protein catabolic process 148
                    positive regulation of proteolysis involved in cellular protein catabolic process 126
                      positive regulation of proteasomal protein catabolic process + 109
                      positive regulation of proteolysis associated with antigen processing and presentation 0
                      positive regulation of ubiquitin-dependent protein catabolic process + 103
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.