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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of CENP-A containing nucleosome assembly
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Accession:GO:1903098 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
Synonyms:exact_synonym: down regulation of CENP-A containing nucleosome assembly at centromere;   down regulation of DNA replication-independent nucleosome assembly at centromere;   down regulation of centromere-specific histone exchange;   down regulation of centromere-specific nucleosome assembly;   down regulation of centromeric DNA replication-independent nucleosome assembly;   downregulation of CENP-A containing nucleosome assembly at centromere;   downregulation of DNA replication-independent nucleosome assembly at centromere;   downregulation of centromere-specific histone exchange;   downregulation of centromere-specific nucleosome assembly;   downregulation of centromeric DNA replication-independent nucleosome assembly;   negative regulation of DNA replication-independent nucleosome assembly at centromere;   negative regulation of centromere-specific histone exchange;   negative regulation of centromere-specific nucleosome assembly;   negative regulation of centromeric DNA replication-independent nucleosome assembly
 narrow_synonym: inhibition of CENP-A containing nucleosome assembly at centromere;   inhibition of DNA replication-independent nucleosome assembly at centromere;   inhibition of centromere-specific histone exchange;   inhibition of centromere-specific nucleosome assembly;   inhibition of centromeric DNA replication-independent nucleosome assembly
 related_synonym: down regulation of CENP-A deposition;   down regulation of CENP-A loading;   down regulation of CenH3-containing nucleosome assembly at centromere;   down regulation of centromere specific nucleosome exchange;   downregulation of CENP-A deposition;   downregulation of CENP-A loading;   downregulation of CenH3-containing nucleosome assembly at centromere;   downregulation of centromere specific nucleosome exchange;   inhibition of CENP-A deposition;   inhibition of CENP-A loading;   inhibition of CenH3-containing nucleosome assembly at centromere;   inhibition of centromere specific nucleosome exchange;   negative regulation of CENP-A deposition;   negative regulation of CENP-A loading;   negative regulation of CenH3-containing nucleosome assembly at centromere;   negative regulation of centromere specific nucleosome exchange


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Term Annotations click to browse term
  biological_process 12564
    negative regulation of biological process 4828
      negative regulation of cellular process 4407
        negative regulation of cellular component organization 685
          negative regulation of protein-containing complex assembly 118
            negative regulation of CENP-A containing nucleosome assembly 0
Path 2
Term Annotations click to browse term
  biological_process 12564
    cellular process 11665
      cellular component organization or biogenesis 5013
        cellular component organization 4933
          organelle organization 3053
            chromosome organization 878
              chromatin organization 557
                chromatin assembly or disassembly 116
                  chromatin assembly 97
                    nucleosome assembly 46
                      DNA replication-independent nucleosome assembly 19
                        CENP-A containing nucleosome assembly 2
                          regulation of CENP-A containing nucleosome assembly 0
                            negative regulation of CENP-A containing nucleosome assembly 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.