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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of calcium ion transmembrane transport
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Accession:GO:1903170 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.
Comment:human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol
Synonyms:exact_synonym: down regulation of calcium ion membrane transport;   down regulation of calcium ion transmembrane transport;   down regulation of transmembrane calcium transport;   downregulation of calcium ion membrane transport;   downregulation of calcium ion transmembrane transport;   downregulation of transmembrane calcium transport;   negative regulation of calcium ion membrane transport;   negative regulation of transmembrane calcium transport
 narrow_synonym: inhibition of calcium ion membrane transport;   inhibition of calcium ion transmembrane transport;   inhibition of transmembrane calcium transport


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negative regulation of calcium ion transmembrane transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:625678
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
G Cbarp CACN subunit beta associated regulatory protein JBrowse link 7 12,433,422 12,441,048 RGD:1624291
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043333
negative regulation of ATPase-coupled calcium transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC691807 hypothetical protein LOC691807 JBrowse link 2 227,095,487 227,097,247 RGD:1600115
RGD:1624291
G Mrln myoregulin JBrowse link 20 19,703,628 19,720,596 RGD:1624291
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
RGD:1600115
G Sln sarcolipin JBrowse link 8 58,431,407 58,435,654 RGD:1600115
RGD:1624291
G Smim6 small integral membrane protein 6 JBrowse link 10 104,461,510 104,470,238 RGD:1624291
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
negative regulation of calcium ion export across plasma membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:1624291
RGD:1600115
negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
G Sestd1 SEC14 and spectrin domain containing 1 JBrowse link 3 64,037,814 64,134,973 RGD:1624291
RGD:1600115
negative regulation of calcium ion transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:8554004
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:1624291
RGD:1600115
negative regulation of calcium:sodium antiporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dysf dysferlin JBrowse link 4 115,700,942 115,901,873 RGD:1624291
RGD:1600115
G Rem1 RRAD and GEM like GTPase 1 JBrowse link 3 148,108,500 148,116,992 RGD:1600115
G Rem2 RRAD and GEM like GTPase 2 JBrowse link 15 33,121,273 33,125,752 RGD:1600115
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 19 561,696 564,929 RGD:1600115
negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcrl5 Fc receptor-like 5 JBrowse link 2 186,776,466 186,797,900 RGD:1624291
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
G Ntsr1 neurotensin receptor 1 JBrowse link 3 175,982,313 176,046,345 RGD:727385
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:7206836
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:731229
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:731229
G Trdn triadin JBrowse link 1 25,403,390 25,787,664 RGD:7327230
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1600115
RGD:1624291
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:1624291
RGD:1600115
RGD:2314601
G Clic2 chloride intracellular channel 2 JBrowse link 20 295,338 310,363 RGD:1624291
RGD:1600115
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1624291
RGD:1600115
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115
negative regulation of store-operated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1600115
RGD:1624291
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cabp1 calcium binding protein 1 JBrowse link 12 47,185,449 47,209,785 RGD:7207144
G Cacna1f calcium voltage-gated channel subunit alpha1 F JBrowse link X 15,712,709 15,741,135 RGD:1624291
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:13514097
G Cbarp CACN subunit beta associated regulatory protein JBrowse link 7 12,433,422 12,441,048 RGD:10047103
RGD:13792537
RGD:1624291
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:1624291
RGD:1600115
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:8554169
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:1624291
RGD:1600115
G Fmr1 fragile X mental retardation 1 JBrowse link X 154,684,924 154,722,369 RGD:11059581
G Gnb5 G protein subunit beta 5 JBrowse link 8 82,248,951 82,286,493 RGD:1600115
RGD:1624291
G Gpr35 G protein-coupled receptor 35 JBrowse link 9 100,129,428 100,141,269 RGD:1624291
RGD:1600115
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835002

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17967
    negative regulation of biological process 5383
      negative regulation of transport 574
        negative regulation of ion transport 185
          negative regulation of calcium ion transport 74
            negative regulation of calcium ion transmembrane transport 47
              negative regulation of calcium import into the mitochondrion 0
              negative regulation of calcium ion export across plasma membrane 1
              negative regulation of calcium ion import across plasma membrane 0
              negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 2
              negative regulation of calcium ion transmembrane transporter activity + 37
              negative regulation of release of sequestered calcium ion into cytosol + 17
Path 2
Term Annotations click to browse term
  biological_process 17967
    localization 6025
      establishment of localization 4624
        transport 4483
          ion transport 1710
            cation transport 1219
              divalent inorganic cation transport 501
                divalent metal ion transport 496
                  calcium ion transport 450
                    regulation of calcium ion transport 289
                      negative regulation of calcium ion transport 74
                        negative regulation of calcium ion transmembrane transport 47
                          negative regulation of calcium import into the mitochondrion 0
                          negative regulation of calcium ion export across plasma membrane 1
                          negative regulation of calcium ion import across plasma membrane 0
                          negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 2
                          negative regulation of calcium ion transmembrane transporter activity + 37
                          negative regulation of release of sequestered calcium ion into cytosol + 17
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.