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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein maturation
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Accession:GO:1903318 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.
Synonyms:exact_synonym: down regulation of protein maturation;   downregulation of protein maturation
 narrow_synonym: inhibition of protein maturation


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inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:1624291
RGD:1600115
RGD:13792537
G Cst7 cystatin F JBrowse link 3 146,363,913 146,373,365 RGD:1624291
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047164
RGD:10047212
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l12 BCL2 like 12 JBrowse link 1 100,984,550 100,993,269 RGD:1624291
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:13792537
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:13792537
G Birc7 baculoviral IAP repeat-containing 7 JBrowse link 3 176,438,335 176,443,864 RGD:13792537
G Fcmr Fc fragment of IgM receptor JBrowse link 13 47,602,701 47,617,065 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of plasminogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpb2 carboxypeptidase B2 JBrowse link 15 57,290,849 57,339,762 RGD:7243115
G Ctsz cathepsin Z JBrowse link 3 172,527,107 172,537,877 RGD:1624291
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:1600115
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:1624291
RGD:1600115
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
negative regulation of protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp4 acid phosphatase 4 JBrowse link 1 100,226,311 100,234,536 RGD:1624291
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:1624291
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 JBrowse link 3 111,160,205 111,163,425 RGD:1624291
RGD:1600115
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:11566024
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
G Glg1 golgi glycoprotein 1 JBrowse link 19 42,983,879 43,088,074 RGD:1624291
RGD:1600115
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:1624291
RGD:1600115
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like JBrowse link 1 169,720,247 169,721,788 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:2317364
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:9999170
G Snx12 sorting nexin 12 JBrowse link X 70,989,822 71,127,330 RGD:1624291
G Tmem59 transmembrane protein 59 JBrowse link 5 126,783,061 126,804,177 RGD:1624291
G Tmem98 transmembrane protein 98 JBrowse link 10 68,173,380 68,184,289 RGD:1600115
RGD:1624291
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:9586053
zymogen inhibition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    negative regulation of biological process 5553
      negative regulation of metabolic process 3059
        negative regulation of macromolecule metabolic process 2780
          negative regulation of gene expression 1848
            negative regulation of protein maturation 32
              negative regulation of N-terminal peptidyl-lysine acetylation 0
              negative regulation of N-terminal peptidyl-methionine acetylation 0
              negative regulation of protein processing + 32
Path 2
Term Annotations click to browse term
  biological_process 19334
    metabolic process 11555
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          gene expression 5525
            regulation of gene expression 4228
              negative regulation of gene expression 1848
                negative regulation of protein maturation 32
                  negative regulation of N-terminal peptidyl-lysine acetylation 0
                  negative regulation of N-terminal peptidyl-methionine acetylation 0
                  negative regulation of protein processing + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.