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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of reactive oxygen species biosynthetic process
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Accession:GO:1903426 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.
Synonyms:exact_synonym: regulation of reactive oxygen species anabolism;   regulation of reactive oxygen species biosynthesis;   regulation of reactive oxygen species formation;   regulation of reactive oxygen species synthesis
 related_synonym: regulation of ROS formation;   regulation of ROS generation;   regulation of reactive oxygen species generation


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regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:1624291
RGD:1600115
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Ccn6 cellular communication network factor 6 JBrowse link 20 44,237,491 44,255,064 RGD:1624291
G LOC100909612 mitochondrial brown fat uncoupling protein 1-like JBrowse link 19 29,395,702 29,400,389 RGD:1600115
G Slc25a33 solute carrier family 25 member 33 JBrowse link 5 166,701,463 166,726,794 RGD:1624291
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
G Ucp1 uncoupling protein 1 JBrowse link 19 24,456,976 24,464,808 RGD:11541111
RGD:1624291
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctns cystinosin, lysosomal cystine transporter JBrowse link 10 59,749,250 59,772,475 RGD:12910938
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:7349317
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:13601987
G Mpv17l MPV17 mitochondrial inner membrane protein like JBrowse link 10 3,321,488 3,359,219 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694322
negative regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 8 23,142,733 23,149,067 RGD:1624291
RGD:1600115
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:633683
G Epor erythropoietin receptor JBrowse link 8 22,969,737 22,974,468 RGD:11041656
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:2303775
G Gla galactosidase, alpha JBrowse link X 105,405,915 105,417,331 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1598631
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:2317291
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1600115
RGD:1624291
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
RGD:1600115
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:1624291
RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590175
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1600115
RGD:1624291
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:1624291
RGD:1600115
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317158
G Wdr35 WD repeat domain 35 JBrowse link 6 34,094,291 34,152,048 RGD:11553926
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
negative regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcd1 ATP binding cassette subfamily D member 1 JBrowse link X 157,073,860 157,095,652 RGD:1624291
RGD:1600115
G Abcd2 ATP binding cassette subfamily D member 2 JBrowse link 7 132,294,564 132,343,169 RGD:1624291
RGD:1600115
G Atp5mc1 ATP synthase membrane subunit c locus 1 JBrowse link 10 83,895,941 83,898,640 RGD:13800744
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:11341712
G Coa8 cytochrome c oxidase assembly factor 8 JBrowse link 6
6
136,185,772
136,279,476
136,210,936
136,304,317
RGD:1624291
RGD:1600115
G Ctns cystinosin, lysosomal cystine transporter JBrowse link 10 59,749,250 59,772,475 RGD:12910938
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 JBrowse link 8 85,838,594 85,841,816 RGD:10401126
G Hbp1 HMG-box transcription factor 1 JBrowse link 6 51,231,479 51,257,699 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:10402548
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910717
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 1 162,369,801 162,376,024 RGD:11040458
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413842
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9585767
G Slc30a10 solute carrier family 30, member 10 JBrowse link 13 103,396,295 103,406,759 RGD:1624291
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Duoxa1 dual oxidase maturation factor 1 JBrowse link 3 114,241,057 114,251,720 RGD:1624291
G Duoxa2 dual oxidase maturation factor 2 JBrowse link 3 114,236,718 114,240,086 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910740
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:13506652
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:27095884
G Zfp13 zinc finger protein 13 JBrowse link 10 12,908,643 12,916,784 RGD:1624291
positive regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8548892
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:1624291
RGD:13792537
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:2313017
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:2313325
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9586000
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:727432
RGD:13792537
RGD:1624291
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 20 5,049,260 5,052,573 RGD:13792537
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:9685181
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:727463
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:1624291
RGD:1600115
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:1600239
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306941
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
RGD:1600115
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1600239
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641934
G Klf2 Kruppel-like factor 2 JBrowse link 16 19,223,087 19,225,037 RGD:1624291
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:1624291
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like JBrowse link 20 3,242,236 3,253,995 RGD:1624291
G LOC103692716 heat shock protein HSP 90-alpha JBrowse link 6 135,044,833 135,050,417 RGD:1600115
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304240
G Mir29b1 microRNA 29b-1 JBrowse link 4 58,344,310 58,344,390 RGD:13702880
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
RGD:13792525
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10041012
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135054
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:10041069
G Ptx3 pentraxin 3 JBrowse link 2 158,097,843 158,103,653 RGD:1624291
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 JBrowse link 20 1,814,661 1,833,033 RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:11535100
RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10042970
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1600115
RGD:1624291
G Tlr5 toll-like receptor 5 JBrowse link 13 101,364,784 101,385,764 RGD:1643119
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:2317115
G Ulbp1 UL16 binding protein 1 JBrowse link 1 1,181,301 1,200,526 RGD:1624291
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgrb1 adhesion G protein-coupled receptor B1 JBrowse link 7 115,766,484 115,828,514 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Clcn3 chloride voltage-gated channel 3 JBrowse link 16 32,448,821 32,520,649 RGD:1624291
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:1624291
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:10402204
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:12910994
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:9681442
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:10402792
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910740
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:9590189
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Rab27a RAB27A, member RAS oncogene family JBrowse link 8 79,722,334 79,776,228 RGD:1624291
G Slc5a3 solute carrier family 5 member 3 JBrowse link 11 32,229,366 32,231,812 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:634667
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:1600115
RGD:1624291
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1624291
G Gchfr GTP cyclohydrolase I feedback regulator JBrowse link 3 110,975,923 110,979,957 RGD:728623
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:13792550
G Nos1ap nitric oxide synthase 1 adaptor protein JBrowse link 13 88,653,123 88,943,976 RGD:8553554
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:13792550
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:13792550

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      biosynthetic process 5984
        reactive oxygen species biosynthetic process 134
          regulation of reactive oxygen species biosynthetic process 115
            negative regulation of reactive oxygen species biosynthetic process + 40
            positive regulation of reactive oxygen species biosynthetic process + 66
            regulation of hydrogen peroxide biosynthetic process + 11
            regulation of nitric oxide biosynthetic process + 75
Path 2
Term Annotations click to browse term
  biological_process 19678
    biological regulation 13599
      regulation of biological process 12921
        regulation of cellular process 12405
          regulation of cellular metabolic process 6112
            regulation of reactive oxygen species metabolic process 218
              regulation of reactive oxygen species biosynthetic process 115
                negative regulation of reactive oxygen species biosynthetic process + 40
                positive regulation of reactive oxygen species biosynthetic process + 66
                regulation of hydrogen peroxide biosynthetic process + 11
                regulation of nitric oxide biosynthetic process + 75
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.