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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TORC1 signaling
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Accession:GO:1903432 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TORC1 signaling.
Synonyms:exact_synonym: regulation of TORC1 signal transduction


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regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9orf72 C9orf72-SMCR8 complex subunit ISO (MGI:MGI:5811684|PMID:27875531)
(PMID:27559131)
UniProtKB PMID:27559131, PMID:27875531 MGI:MGI:5811684 NCBI chr 9:27,395,054...27,422,282
Ensembl chr 9:28,001,813...28,022,066
JBrowse link
G DGKQ diacylglycerol kinase theta ISO (PMID:23767959) ParkinsonsUK-UCL PMID:23767959 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724
JBrowse link
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 ISO (PMID:23415227) UniProtKB PMID:23415227 NCBI chr 1:182,237,556...182,255,984
Ensembl chr 1:186,517,041...186,530,272
JBrowse link
G RRAGC Ras related GTP binding C ISO (PMID:27222292) UniProtKB PMID:27222292 NCBI chr 1:38,110,578...38,132,179
Ensembl chr 1:39,456,768...39,478,244
JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit ISO (PMID:27559131) UniProtKB PMID:27559131 NCBI chr17:32,858,205...32,871,132
Ensembl chr17:37,884,037...37,896,972
JBrowse link
negative regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALG13 ALG13 UDP-N-acetylglucosaminyltransferase subunit ISO (MGI:MGI:6306805|PMID:30872163) MGI PMID:30872163 MGI:MGI:6306805 NCBI chr  X:100,794,882...100,874,083
Ensembl chr  X:111,253,717...111,332,534
JBrowse link
G ATM ATM serine/threonine kinase ISO (PMID:23878245)
(MGI:MGI:5509101|PMID:23878245)
ParkinsonsUK-UCL PMID:23878245 MGI:MGI:5509101 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G BMT2 base methyltransferase of 25S rRNA 2 homolog ISO (PMID:29123071) UniProtKB PMID:29123071 NCBI chr 7:104,786,390...104,905,357
Ensembl chr 7:117,488,026...117,607,033
JBrowse link
G C12H12orf66 chromosome 12 C12orf66 homolog ISO (PMID:28199306) UniProtKB PMID:28199306 NCBI chr12:24,691,658...24,721,618
Ensembl chr12:25,174,580...25,219,830
JBrowse link
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 ISO (PMID:26972053) UniProtKB PMID:26972053 NCBI chr22:11,321,259...11,325,787
Ensembl chr22:29,123,198...29,127,736
JBrowse link
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 ISO (PMID:26972053) UniProtKB PMID:26972053 Ensembl chr 7:82,068,521...82,075,387 JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit ISO (PMID:25457612), (PMID:29769719) UniProtKB PMID:25457612, PMID:29769719 NCBI chr22:12,774,147...12,929,261 JBrowse link
G FNIP1 folliculin interacting protein 1 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chr 5:127,070,906...127,219,548
Ensembl chr 5:133,235,501...133,384,218
JBrowse link
G FNIP2 folliculin interacting protein 2 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chr 4:151,086,854...151,224,192
Ensembl chr 4:162,896,805...163,032,167
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 ISO (PMID:28199306) UniProtKB PMID:28199306 NCBI chr12:2,933,227...2,980,509
Ensembl chr12:2,865,297...2,877,555
JBrowse link
G KPTN kaptin, actin binding protein ISO (PMID:28199306) UniProtKB PMID:28199306 NCBI chr19:44,467,344...44,478,150
Ensembl chr19:53,122,663...53,131,805
JBrowse link
G RNF152 ring finger protein 152 ISO (MGI:MGI:5644195|PMID:25936802)
(PMID:25936802)
UniProtKB PMID:25936802 MGI:MGI:5644195 NCBI chr18:55,180,955...55,264,164
Ensembl chr18:58,507,684...58,508,295
JBrowse link
G SESN1 sestrin 1 ISO (MGI:MGI:5604284|PMID:25259925)
(PMID:18692468), (PMID:25263562)
UniProtKB PMID:18692468, PMID:25259925, PMID:25263562 MGI:MGI:5604284 NCBI chr 6:106,789,911...106,896,382
Ensembl chr 6:110,839,631...110,946,276
JBrowse link
G SESN2 sestrin 2 ISO (PMID:18692468), (PMID:24947615), (PMID:25263562), (PMID:25457612), (PMID:26449471), (PMID:26586190), (PMID:26612684)
(MGI:MGI:5604284|PMID:25259925), (MGI:MGI:5688277|PMID:24947615)
UniProtKB PMID:18692468, PMID:24947615, PMID:25259925, PMID:25263562, PMID:25457612, PMID:26449471, PMID:26586190, PMID:26612684 MGI:MGI:5604284, MGI:MGI:5688277 NCBI chr 1:27,518,248...27,541,264
Ensembl chr 1:28,555,072...28,577,931
JBrowse link
G SESN3 sestrin 3 ISO (MGI:MGI:5604284|PMID:25259925)
(PMID:25263562)
UniProtKB PMID:25259925, PMID:25263562 MGI:MGI:5604284 NCBI chr11:90,184,571...90,249,825
Ensembl chr11:93,714,916...93,773,679
JBrowse link
G SPAAR small regulatory polypeptide of amino acid response ISO (PMID:28024296)
(MGI:MGI:5822922|PMID:28024296)
UniProtKB PMID:28024296 MGI:MGI:5822922 NCBI chr 9:35,760,064...35,762,224
Ensembl chr 9:36,563,148...36,563,420
JBrowse link
G STK11 serine/threonine kinase 11 ISO (PMID:23878245) ParkinsonsUK-UCL PMID:23878245 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G SZT2 SZT2 subunit of KICSTOR complex ISO (MGI:MGI:5883356|PMID:28199306), (MGI:MGI:5897504|PMID:28199315)
(PMID:28199306), (PMID:28199315)
UniProtKB PMID:28199306, PMID:28199315 MGI:MGI:5883356, MGI:MGI:5897504 NCBI chr 1:42,691,292...42,754,046
Ensembl chr 1:44,068,998...44,129,456
JBrowse link
G TSC2 TSC complex subunit 2 ISO (MGI:MGI:5509101|PMID:23878245) ParkinsonsUK-UCL PMID:23878245 MGI:MGI:5509101 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
positive regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A ISO (PMID:28223137) UniProtKB PMID:28223137 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512
JBrowse link
G GPR137B G protein-coupled receptor 137B ISO (PMID:31036939) UniProt PMID:31036939 NCBI chr 1:211,709,507...211,775,846
Ensembl chr 1:216,696,105...216,778,370
JBrowse link
G KLHL22 kelch like family member 22 ISO (PMID:29769719)
(MGI:MGI:6162296|PMID:29769719)
UniProtKB PMID:29769719 MGI:MGI:6162296 Ensembl chr22:19,122,875...19,174,842 JBrowse link
G LARS1 leucyl-tRNA synthetase 1 ISO (PMID:22424946) CAFA PMID:22424946 NCBI chr 5:141,562,798...141,631,388
Ensembl chr 5:147,578,042...147,646,834
JBrowse link
G PIH1D1 PIH1 domain containing 1 ISO (PMID:24036451) UniProtKB PMID:24036451 NCBI chr19:46,459,855...46,465,882
Ensembl chr19:55,381,803...55,387,664
JBrowse link
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 ISO (PMID:29644770)
(MGI:MGI:6304515|PMID:29644770)
UniProt PMID:29644770 MGI:MGI:6304515 NCBI chr14:1,332,403...1,336,157
Ensembl chr14:19,384,634...19,388,140
JBrowse link
G RRAGA Ras related GTP binding A ISO (PMID:25936802) UniProtKB PMID:25936802 NCBI chr 9:18,868,781...18,870,356
Ensembl chr 9:19,362,599...19,363,540
JBrowse link
G RRAGB Ras related GTP binding B ISO (PMID:22424946) CAFA PMID:22424946 NCBI chr  X:48,003,566...48,042,285
Ensembl chr  X:56,155,662...56,194,335
JBrowse link
G RRAGD Ras related GTP binding D ISO (PMID:22424946) CAFA PMID:22424946 NCBI chr 6:87,237,442...87,285,579
Ensembl chr 6:90,511,250...90,558,822
JBrowse link
G SEH1L SEH1 like nucleoporin ISO (PMID:25457612) UniProtKB PMID:25457612 NCBI chr18:1,342,928...1,379,719
Ensembl chr18:16,464,446...16,500,693
JBrowse link
G SIK3 SIK family kinase 3 ISO (PMID:30232230) UniProt PMID:30232230 NCBI chr11:111,680,884...111,932,424
Ensembl chr11:115,613,478...115,730,158
JBrowse link
G TELO2 telomere maintenance 2 ISO (PMID:24036451) UniProtKB PMID:24036451 NCBI chr16:112,856...130,175
Ensembl chr16:1,548,212...1,566,337
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    cellular process 11625
      signal transduction 3809
        intracellular signal transduction 2043
          TOR signaling 116
            regulation of TOR signaling 98
              regulation of TORC1 signaling 36
                negative regulation of TORC1 signaling 19
                positive regulation of TORC1 signaling 12
Path 2
Term Annotations click to browse term
  biological_process 12529
    biological regulation 9138
      regulation of biological process 8652
        regulation of cellular process 8181
          signal transduction 3809
            intracellular signal transduction 2043
              TOR signaling 116
                regulation of TOR signaling 98
                  regulation of TORC1 signaling 36
                    negative regulation of TORC1 signaling 19
                    positive regulation of TORC1 signaling 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.