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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TORC1 signaling
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Accession:GO:1903432 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TORC1 signaling.
Synonyms:exact_synonym: regulation of TORC1 signal transduction


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regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9orf72 C9orf72-SMCR8 complex subunit ISO (PMID:27559131)
(MGI:MGI:5811684|PMID:27875531)
UniProtKB PMID:27559131, PMID:27875531 MGI:MGI:5811684 NCBI chrNW_004955472:7,299,092...7,337,591 JBrowse link
G Dgkq diacylglycerol kinase theta ISO (PMID:23767959) ParkinsonsUK-UCL PMID:23767959 NCBI chrNW_004955514:452,548...475,240 JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 ISO (PMID:23415227) UniProtKB PMID:23415227 NCBI chrNW_004955406:42,190,043...42,199,323 JBrowse link
G Rragc Ras related GTP binding C ISO (PMID:27222292) UniProtKB PMID:27222292 NCBI chrNW_004955452:16,469,426...16,486,336 JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit ISO (PMID:27559131) UniProtKB PMID:27559131 NCBI chrNW_004955478:11,002,174...11,015,123 JBrowse link
negative regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg13 ALG13 UDP-N-acetylglucosaminyltransferase subunit ISO (MGI:MGI:6306805|PMID:30872163) MGI PMID:30872163 MGI:MGI:6306805 NCBI chrNW_004955490:4,069,866...4,140,494 JBrowse link
G Atm ATM serine/threonine kinase ISO (PMID:23878245)
(MGI:MGI:5509101|PMID:23878245)
ParkinsonsUK-UCL PMID:23878245 MGI:MGI:5509101 NCBI chrNW_004955412:10,422,753...10,531,406 JBrowse link
G Bmt2 base methyltransferase of 25S rRNA 2 homolog ISO (PMID:29123071) UniProtKB PMID:29123071 NCBI chrNW_004955432:19,046,121...19,107,178 JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 ISO (PMID:26972053) UniProtKB PMID:26972053 NCBI chrNW_004955455:4,530,842...4,535,358 JBrowse link
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 ISO (PMID:26972053) UniProtKB PMID:26972053 NCBI chrNW_004955456:13,242,401...13,282,469 JBrowse link
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit ISO (PMID:25457612), (PMID:29769719) UniProtKB PMID:25457612, PMID:29769719 NCBI chrNW_004955455:5,881,631...6,005,514 JBrowse link
G Fnip1 folliculin interacting protein 1 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chrNW_004955408:3,117,258...3,238,223 JBrowse link
G Fnip2 folliculin interacting protein 2 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chrNW_004955471:12,329,686...12,444,782 JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 ISO (PMID:28199306) UniProtKB PMID:28199306 NCBI chrNW_004955429:18,356,642...18,372,928 JBrowse link
G Kptn kaptin, actin binding protein ISO (PMID:28199306) UniProtKB PMID:28199306 NCBI chrNW_004955574:1,321,356...1,329,132 JBrowse link
G LOC102008505 chromosome unknown open reading frame, human C12orf66 ISO (PMID:28199306) UniProtKB PMID:28199306 NCBI chrNW_004955458:11,027,550...11,048,563 JBrowse link
G Rnf152 ring finger protein 152 ISO (PMID:25936802)
(MGI:MGI:5644195|PMID:25936802)
UniProtKB PMID:25936802 MGI:MGI:5644195 NCBI chrNW_004955402:45,774,565...45,846,649 JBrowse link
G Sesn1 sestrin 1 ISO (PMID:18692468), (PMID:25263562)
(MGI:MGI:5604284|PMID:25259925)
UniProtKB PMID:18692468, PMID:25259925, PMID:25263562 MGI:MGI:5604284 NCBI chrNW_004955411:34,033,986...34,051,171 JBrowse link
G Sesn2 sestrin 2 ISO (MGI:MGI:5604284|PMID:25259925), (MGI:MGI:5688277|PMID:24947615)
(PMID:18692468), (PMID:24947615), (PMID:25263562), (PMID:25457612), (PMID:26449471), (PMID:26586190), (PMID:26612684)
UniProtKB PMID:18692468, PMID:24947615, PMID:25259925, PMID:25263562, PMID:25457612, PMID:26449471, PMID:26586190, PMID:26612684 MGI:MGI:5604284, MGI:MGI:5688277 NCBI chrNW_004955452:7,392,644...7,417,204 JBrowse link
G Sesn3 sestrin 3 ISO (PMID:25263562)
(MGI:MGI:5604284|PMID:25259925)
UniProtKB PMID:25259925, PMID:25263562 MGI:MGI:5604284 NCBI chrNW_004955412:100,335...125,395 JBrowse link
G Stk11 serine/threonine kinase 11 ISO (PMID:23878245) ParkinsonsUK-UCL PMID:23878245 NCBI chrNW_004955495:6,678,195...6,699,408 JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex ISO (MGI:MGI:5883356|PMID:28199306), (MGI:MGI:5897504|PMID:28199315)
(PMID:28199306), (PMID:28199315)
UniProtKB PMID:28199306, PMID:28199315 MGI:MGI:5883356, MGI:MGI:5897504 NCBI chrNW_004955537:2,968,839...3,017,863 JBrowse link
G Tsc2 TSC complex subunit 2 ISO (MGI:MGI:5509101|PMID:23878245) ParkinsonsUK-UCL PMID:23878245 MGI:MGI:5509101 NCBI chrNW_004955442:15,178,356...15,216,978 JBrowse link
positive regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A ISO (PMID:28223137) UniProtKB PMID:28223137 NCBI chrNW_004955442:7,369,616...7,584,052 JBrowse link
G Gpr137b G protein-coupled receptor 137B ISO (PMID:31036939) UniProt PMID:31036939 NCBI chrNW_004955492:3,916,536...3,952,330 JBrowse link
G Klhl22 kelch like family member 22 ISO (MGI:MGI:6162296|PMID:29769719)
(PMID:29769719)
UniProtKB PMID:29769719 MGI:MGI:6162296 NCBI chrNW_004955442:19,010,971...19,051,300 JBrowse link
G Lars1 leucyl-tRNA synthetase 1 ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955415:7,923,292...7,983,757 JBrowse link
G Pih1d1 PIH1 domain containing 1 ISO (PMID:24036451) UniProtKB PMID:24036451 NCBI chrNW_004955559:1,390,823...1,395,550 JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 ISO (MGI:MGI:6304515|PMID:29644770)
(PMID:29644770)
UniProt PMID:29644770 MGI:MGI:6304515 NCBI chrNW_004955550:1,275,921...1,279,262 JBrowse link
G Rraga Ras related GTP binding A ISO (PMID:25936802) UniProtKB PMID:25936802 NCBI chrNW_004955434:21,509,528...21,510,885 JBrowse link
G Rragb Ras related GTP binding B ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955475:2,662,969...2,692,253 JBrowse link
G Rragd Ras related GTP binding D ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955411:16,111,931...16,155,662 JBrowse link
G Seh1l SEH1 like nucleoporin ISO (PMID:25457612) UniProtKB PMID:25457612 NCBI chrNW_004955402:679,109...698,624 JBrowse link
G Sik3 SIK family kinase 3 ISO (PMID:30232230) UniProt PMID:30232230 NCBI chrNW_004955412:18,177,175...18,280,687 JBrowse link
G Telo2 telomere maintenance 2 ISO (PMID:24036451) UniProtKB PMID:24036451 NCBI chrNW_004955442:15,719,082...15,733,527 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11862
    cellular process 11059
      signal transduction 3673
        intracellular signal transduction 1974
          TOR signaling 117
            regulation of TOR signaling 99
              regulation of TORC1 signaling 35
                negative regulation of TORC1 signaling 18
                positive regulation of TORC1 signaling 12
Path 2
Term Annotations click to browse term
  biological_process 11862
    biological regulation 8697
      regulation of biological process 8250
        regulation of cellular process 7832
          signal transduction 3673
            intracellular signal transduction 1974
              TOR signaling 117
                regulation of TOR signaling 99
                  regulation of TORC1 signaling 35
                    negative regulation of TORC1 signaling 18
                    positive regulation of TORC1 signaling 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.